FR2935001B1 - Emulsion fluorescente - Google Patents
Emulsion fluorescenteInfo
- Publication number
- FR2935001B1 FR2935001B1 FR0804601A FR0804601A FR2935001B1 FR 2935001 B1 FR2935001 B1 FR 2935001B1 FR 0804601 A FR0804601 A FR 0804601A FR 0804601 A FR0804601 A FR 0804601A FR 2935001 B1 FR2935001 B1 FR 2935001B1
- Authority
- FR
- France
- Prior art keywords
- oil phase
- lambda
- droplets
- label
- fluorescent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000000839 emulsion Substances 0.000 title abstract 4
- 239000012071 phase Substances 0.000 abstract 6
- 239000007850 fluorescent dye Substances 0.000 abstract 3
- 238000005538 encapsulation Methods 0.000 abstract 2
- 230000003287 optical effect Effects 0.000 abstract 2
- 239000004094 surface-active agent Substances 0.000 abstract 2
- 239000008346 aqueous phase Substances 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- 238000000799 fluorescence microscopy Methods 0.000 abstract 1
- 238000003384 imaging method Methods 0.000 abstract 1
- 238000002372 labelling Methods 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 230000005501 phase interface Effects 0.000 abstract 1
- 230000003381 solubilizing effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0063—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres
- A61K49/0069—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form
- A61K49/0076—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion
- A61K49/0078—Preparation for luminescence or biological staining characterised by a special physical or galenical form, e.g. emulsions, microspheres the agent being in a particular physical galenical form dispersion, suspension, e.g. particles in a liquid, colloid, emulsion microemulsion, nanoemulsion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0032—Methine dyes, e.g. cyanine dyes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/001—Preparation for luminescence or biological staining
- A61K49/0013—Luminescence
- A61K49/0017—Fluorescence in vivo
- A61K49/0019—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules
- A61K49/0021—Fluorescence in vivo characterised by the fluorescent group, e.g. oligomeric, polymeric or dendritic molecules the fluorescent group being a small organic molecule
- A61K49/0032—Methine dyes, e.g. cyanine dyes
- A61K49/0034—Indocyanine green, i.e. ICG, cardiogreen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/533—Production of labelled immunochemicals with fluorescent label
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0804601A FR2935001B1 (fr) | 2008-08-14 | 2008-08-14 | Emulsion fluorescente |
JP2011522565A JP2011530577A (ja) | 2008-08-14 | 2009-08-11 | 蛍光エマルジョン |
US13/058,984 US20110195029A1 (en) | 2008-08-14 | 2009-08-11 | Fluorescent emulsion |
CN200980139595.6A CN102170913A (zh) | 2008-08-14 | 2009-08-11 | 荧光乳液 |
EP09786223A EP2331144A1 (fr) | 2008-08-14 | 2009-08-11 | Émulsion fluorescente |
CA2733994A CA2733994A1 (fr) | 2008-08-14 | 2009-08-11 | Emulsion fluorescente |
PCT/IB2009/006766 WO2010018460A1 (fr) | 2008-08-14 | 2009-08-11 | Émulsion fluorescente |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0804601A FR2935001B1 (fr) | 2008-08-14 | 2008-08-14 | Emulsion fluorescente |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2935001A1 FR2935001A1 (fr) | 2010-02-19 |
FR2935001B1 true FR2935001B1 (fr) | 2011-12-30 |
Family
ID=40220167
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR0804601A Expired - Fee Related FR2935001B1 (fr) | 2008-08-14 | 2008-08-14 | Emulsion fluorescente |
Country Status (7)
Country | Link |
---|---|
US (1) | US20110195029A1 (fr) |
EP (1) | EP2331144A1 (fr) |
JP (1) | JP2011530577A (fr) |
CN (1) | CN102170913A (fr) |
CA (1) | CA2733994A1 (fr) |
FR (1) | FR2935001B1 (fr) |
WO (1) | WO2010018460A1 (fr) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2934955B1 (fr) | 2008-08-14 | 2011-07-08 | Commissariat Energie Atomique | Encapsulation d'agents therapeutiques lipophiles ou amphiphiles dans des nanoemulsions |
FR2934954B1 (fr) | 2008-08-14 | 2011-07-22 | Commissariat Energie Atomique | Emulsion fluorescente de vert d'indocyanine |
FR2934953B1 (fr) | 2008-08-14 | 2011-01-21 | Commissariat Energie Atomique | Nanoemulsions de nanocristaux |
US20140356293A1 (en) * | 2012-01-20 | 2014-12-04 | The Research Foundation of the State of University of New York | Fluorescent compositions with enhanced fluorescence and methods based thereon |
FR2991196B1 (fr) | 2012-05-29 | 2014-06-27 | Capsum | Nanoparticules ciblantes pour une application biologique |
CN104152138A (zh) * | 2014-06-26 | 2014-11-19 | 苏州科技学院 | 一种弱光频率上转换o/w型微乳液体系 |
CN109187450B (zh) * | 2018-08-01 | 2020-10-27 | 傅英 | 一种基于量子点的生物分子浓度检测方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4906100A (en) * | 1988-05-13 | 1990-03-06 | University Of Cincinnati | Method of detecting adriamycin (doxorubicin) or daunomycin in the environment |
GB2251381B (en) * | 1990-07-19 | 1995-01-25 | Charwell Pharma | Emulsified fluorescein diester diagnostic compositions |
US6540981B2 (en) * | 1997-12-04 | 2003-04-01 | Amersham Health As | Light imaging contrast agents |
ATE257014T1 (de) * | 1997-04-29 | 2004-01-15 | Amersham Health As | Lichtbilderzeugungskontrastmitteln |
US6123923A (en) * | 1997-12-18 | 2000-09-26 | Imarx Pharmaceutical Corp. | Optoacoustic contrast agents and methods for their use |
TW537894B (en) * | 1998-05-26 | 2003-06-21 | Novartis Ag | A spontaneously dispersible pharmaceutical composition comprising a piperidine substance P antagonist |
DE19852245A1 (de) * | 1998-11-12 | 2000-05-18 | Asat Ag Applied Science & Tech | 5-Aminolävulinsäure-Nanoemulsion |
JP2007501797A (ja) * | 2003-08-08 | 2007-02-01 | バーンズ−ジューイッシュ ホスピタル | 造影及び治療用エマルジョン粒子並びにその使用方法 |
EP1563851A1 (fr) * | 2004-02-17 | 2005-08-17 | Yissum Research Development Company of the Hebrew University of Jerusalem | Emulsions cationiques ciblées avec des anticorps pour la livraison de drogues |
US20050255044A1 (en) * | 2004-05-14 | 2005-11-17 | Lomnes Stephen J | Contrast agent for combined modality imaging and methods and systems thereof |
US20070148194A1 (en) * | 2005-11-29 | 2007-06-28 | Amiji Mansoor M | Novel nanoemulsion formulations |
WO2008102065A1 (fr) * | 2007-02-14 | 2008-08-28 | Commissariat A L'energie Atomique | Emulsions fluorescentes pour l'imagerie optique |
JP2010083860A (ja) * | 2008-02-29 | 2010-04-15 | Kyoto Univ | ポリマーナノ微粒子及び光分子イメージング用造影剤 |
-
2008
- 2008-08-14 FR FR0804601A patent/FR2935001B1/fr not_active Expired - Fee Related
-
2009
- 2009-08-11 WO PCT/IB2009/006766 patent/WO2010018460A1/fr active Application Filing
- 2009-08-11 EP EP09786223A patent/EP2331144A1/fr not_active Withdrawn
- 2009-08-11 CA CA2733994A patent/CA2733994A1/fr not_active Abandoned
- 2009-08-11 US US13/058,984 patent/US20110195029A1/en not_active Abandoned
- 2009-08-11 JP JP2011522565A patent/JP2011530577A/ja active Pending
- 2009-08-11 CN CN200980139595.6A patent/CN102170913A/zh active Pending
Also Published As
Publication number | Publication date |
---|---|
CN102170913A (zh) | 2011-08-31 |
JP2011530577A (ja) | 2011-12-22 |
US20110195029A1 (en) | 2011-08-11 |
FR2935001A1 (fr) | 2010-02-19 |
EP2331144A1 (fr) | 2011-06-15 |
CA2733994A1 (fr) | 2010-02-18 |
WO2010018460A1 (fr) | 2010-02-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PLFP | Fee payment |
Year of fee payment: 8 |
|
PLFP | Fee payment |
Year of fee payment: 9 |
|
ST | Notification of lapse |
Effective date: 20180430 |