PE13999A1 - Composiciones farmaceuticas estabilizadas a base de quinupristina y de dalfopristina y su preparacion - Google Patents

Composiciones farmaceuticas estabilizadas a base de quinupristina y de dalfopristina y su preparacion

Info

Publication number
PE13999A1
PE13999A1 PE1997001017A PE00101797A PE13999A1 PE 13999 A1 PE13999 A1 PE 13999A1 PE 1997001017 A PE1997001017 A PE 1997001017A PE 00101797 A PE00101797 A PE 00101797A PE 13999 A1 PE13999 A1 PE 13999A1
Authority
PE
Peru
Prior art keywords
dalphopristine
quinupristine
preparation
composition
pharmaceutical compositions
Prior art date
Application number
PE1997001017A
Other languages
English (en)
Inventor
Paul Bounine Jean
Conrath Guillaume
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of PE13999A1 publication Critical patent/PE13999A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08Peptides having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

CARACTERIZADAS PORQUE COMPRENDEN: DE 5 mg/ml A 250 mg/ml DE LA ASOCIACION QUINUPRISTINA/DALFOPRISTINA; UNA CANTIDAD AL MENOS ESTEQUIOMETRICA DE ACIDO METANOSULFONICO o HCl; Y OPCIONALMENTE PUEDEN COMPRENDER UN AGENTE ISOTONIZANTE Y/O OTROS ADYUVANTES; EN DONDE EL pH DE LA COMPOSICION ESTA EN EL RANGO DE 3,5 A 5. TAMBIEN SE REFIERE AL PROCEDIMIENTO DE PREPARACION DE DICHA COMPOSICION, QUE COMPRENDE: DISOLVER SIMULTANEA O SUCESIVAMENTE LA QUINUPRISTINA Y A CONTINUACION LA DALFOPRISTINA EN AGUA ACIDIFICADA CON ACIDO METANOSULFONICO o CON HCl, Y A CONTINUACION AJUSTAR EL pH DE 3,5 A 5; FINALMENTE, LA SOLUCION OBTENIDA SE LIOFILIZA Y/O SE CONGELA. LA COMPOSICION ESTABILIZADA, LIOFILIZADA O CONGELADA PRESENTA COMO VENTAJA ESTABILIDAD FISICOQUIMICA OPTIMA QUE PERMITE SU ALMACENAMIENTO Y POR LO TANTO, COMERCIALIZACION, SIENDO UTIL COMO ANTIBACTERIANO PRINCIPALMENTE SOBRE LOS GERMENES RESISTENTES A LA VANCOMICINA
PE1997001017A 1996-11-19 1997-11-13 Composiciones farmaceuticas estabilizadas a base de quinupristina y de dalfopristina y su preparacion PE13999A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9614062A FR2755857B1 (fr) 1996-11-19 1996-11-19 Compositions pharmaceutiques stabilisees, a base de quinupristine et de dalfopristine et leur preparation

Publications (1)

Publication Number Publication Date
PE13999A1 true PE13999A1 (es) 1999-05-05

Family

ID=9497744

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1997001017A PE13999A1 (es) 1996-11-19 1997-11-13 Composiciones farmaceuticas estabilizadas a base de quinupristina y de dalfopristina y su preparacion

Country Status (45)

Country Link
US (1) US5994338A (es)
EP (1) EP0949923B1 (es)
JP (1) JP4278115B2 (es)
KR (1) KR100530836B1 (es)
CN (1) CN1146417C (es)
AP (1) AP998A (es)
AR (1) AR008695A1 (es)
AT (1) ATE223217T1 (es)
AU (1) AU740291B2 (es)
BG (1) BG63621B1 (es)
BR (1) BR9713087A (es)
CA (1) CA2271095C (es)
CO (1) CO4910113A1 (es)
CZ (1) CZ299913B6 (es)
DE (1) DE69715247T2 (es)
DK (1) DK0949923T3 (es)
DZ (1) DZ2349A1 (es)
EA (1) EA002025B1 (es)
EE (1) EE03668B1 (es)
ES (1) ES2179375T3 (es)
FR (1) FR2755857B1 (es)
HK (1) HK1022832A1 (es)
HR (1) HRP970615B1 (es)
HU (1) HUP9904327A3 (es)
IL (2) IL129607A0 (es)
IN (1) IN187038B (es)
JO (1) JO1992B1 (es)
MA (1) MA26448A1 (es)
MY (1) MY123805A (es)
NO (1) NO992399D0 (es)
NZ (1) NZ334949A (es)
OA (1) OA11047A (es)
PE (1) PE13999A1 (es)
PL (1) PL190164B1 (es)
PT (1) PT949923E (es)
RS (1) RS49608B (es)
SA (1) SA97180645B1 (es)
SK (1) SK284311B6 (es)
TN (1) TNSN97184A1 (es)
TR (1) TR199901096T2 (es)
TW (1) TW474816B (es)
UA (1) UA59376C2 (es)
UY (1) UY24780A1 (es)
WO (1) WO1998022107A1 (es)
ZA (1) ZA9710435B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2772272B1 (fr) * 1997-12-16 2000-01-14 Rhone Poulenc Rorer Sa Compositions pharmaceutiques a base de dalfopristine et de quinupristine et leur preparation
HU230656B1 (hu) 1998-09-25 2017-06-28 Cubist Pharmaceuticals Llc Daptomicin alkalmazása
AU776782C (en) * 1999-03-03 2005-04-07 Eli Lilly And Company Echinocandin pharmaceutical formulations containing micelle-forming surfactants
TWI233805B (en) * 1999-07-01 2005-06-11 Fujisawa Pharmaceutical Co Stabilized pharmaceutical composition in lyophilized form as antifungal agent
US6119269A (en) * 1999-09-23 2000-09-19 Imler; Jack Fishing vest with removable storage container system
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
FR2812549B1 (fr) * 2000-08-03 2003-03-21 Aventis Pharma Sa Associations dalfopristine/quinupristine avec le cefpirome
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2549065B1 (fr) * 1983-07-13 1985-10-25 Rhone Poulenc Sante Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2576022B1 (fr) * 1985-01-11 1987-09-11 Rhone Poulenc Sante Nouveaux derives de la pristinamycine ii b, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2599036B1 (fr) * 1986-05-22 1988-09-09 Rhone Poulenc Sante Nouveaux derives de synergistines, leur preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
YU22499A (sh) 2002-03-18
ES2179375T3 (es) 2003-01-16
FR2755857B1 (fr) 1998-12-24
EE9900127A (et) 1999-12-15
CZ299913B6 (cs) 2008-12-29
EA199900479A1 (ru) 2000-02-28
HUP9904327A2 (hu) 2000-06-28
PL190164B1 (pl) 2005-11-30
EE03668B1 (et) 2002-04-15
KR100530836B1 (ko) 2005-11-23
PT949923E (pt) 2003-01-31
SA97180645B1 (ar) 2005-12-12
UA59376C2 (uk) 2003-09-15
HK1022832A1 (en) 2000-08-25
BG103412A (en) 2000-06-30
MA26448A1 (fr) 2004-12-20
HUP9904327A3 (en) 2002-03-28
HRP970615A2 (en) 1998-08-31
EA002025B1 (ru) 2001-12-24
UY24780A1 (es) 2001-08-27
CA2271095A1 (fr) 1998-05-28
IN187038B (es) 2001-12-29
AP998A (en) 2001-08-09
MY123805A (en) 2006-06-30
CN1233959A (zh) 1999-11-03
CN1146417C (zh) 2004-04-21
AU740291B2 (en) 2001-11-01
DK0949923T3 (da) 2002-12-23
BG63621B1 (bg) 2002-07-31
US5994338A (en) 1999-11-30
SK284311B6 (sk) 2005-01-03
WO1998022107A1 (fr) 1998-05-28
IL129607A (en) 2006-08-20
DE69715247T2 (de) 2003-04-30
TW474816B (en) 2002-02-01
AR008695A1 (es) 2000-02-09
NO992399L (no) 1999-05-19
EP0949923B1 (fr) 2002-09-04
DZ2349A1 (fr) 2002-12-28
JO1992B1 (en) 1999-05-15
HRP970615B1 (en) 2002-12-31
JP2001504475A (ja) 2001-04-03
CO4910113A1 (es) 2000-04-24
FR2755857A1 (fr) 1998-05-22
JP4278115B2 (ja) 2009-06-10
BR9713087A (pt) 2000-03-28
RS49608B (sr) 2007-06-04
SK66099A3 (en) 2000-01-18
NO992399D0 (no) 1999-05-19
KR20000053343A (ko) 2000-08-25
ATE223217T1 (de) 2002-09-15
NZ334949A (en) 2000-12-22
CZ174899A3 (cs) 1999-08-11
TNSN97184A1 (fr) 2005-03-15
IL129607A0 (en) 2000-02-29
OA11047A (fr) 2003-03-07
DE69715247D1 (de) 2002-10-10
ZA9710435B (en) 1998-06-10
CA2271095C (fr) 2004-08-03
TR199901096T2 (xx) 1999-07-21
AU5125698A (en) 1998-06-10
EP0949923A1 (fr) 1999-10-20

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Legal Events

Date Code Title Description
FG Grant, registration
FD Application declared void or lapsed