PA8657001A1 - Compuestos de piridazinona - Google Patents

Compuestos de piridazinona

Info

Publication number
PA8657001A1
PA8657001A1 PA20058657001A PA8657001A PA8657001A1 PA 8657001 A1 PA8657001 A1 PA 8657001A1 PA 20058657001 A PA20058657001 A PA 20058657001A PA 8657001 A PA8657001 A PA 8657001A PA 8657001 A1 PA8657001 A1 PA 8657001A1
Authority
PA
Panama
Prior art keywords
compounds
piridazinona
piridazinoma
hepatitis
directed
Prior art date
Application number
PA20058657001A
Other languages
English (en)
Inventor
Stephen E Webber
Yuefen Zhou
Liansheng Li
Original Assignee
Anadys Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anadys Pharmaceuticals Inc filed Critical Anadys Pharmaceuticals Inc
Publication of PA8657001A1 publication Critical patent/PA8657001A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

LA INVENCION SE DIRIGE A COMPUESTOS DE PIRIDAZINOMA Y COMPOSICIONES FARMACEUTICAS QUE CONTIENEN TALES COMPUESTOS QUE SON UTILES EN EL TRATAMIENTO DE INFECCIONES POR VIRUS DE HEPATITIS C
PA20058657001A 2004-12-17 2005-12-19 Compuestos de piridazinona PA8657001A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63661604P 2004-12-17 2004-12-17

Publications (1)

Publication Number Publication Date
PA8657001A1 true PA8657001A1 (es) 2006-08-03

Family

ID=36588590

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20058657001A PA8657001A1 (es) 2004-12-17 2005-12-19 Compuestos de piridazinona

Country Status (21)

Country Link
US (1) US7425552B2 (es)
EP (1) EP1824847A2 (es)
JP (1) JP2008526687A (es)
KR (1) KR20070100743A (es)
CN (1) CN101137651A (es)
AP (1) AP2007004040A0 (es)
AR (1) AR054214A1 (es)
AU (1) AU2005316396A1 (es)
CA (1) CA2589527A1 (es)
CR (1) CR9204A (es)
EA (1) EA200701297A1 (es)
GT (1) GT200500373A (es)
IL (1) IL183510A0 (es)
MX (1) MX2007007264A (es)
NO (1) NO20073105L (es)
PA (1) PA8657001A1 (es)
PE (1) PE20060871A1 (es)
SV (1) SV2006002347A (es)
TW (1) TW200635596A (es)
UY (1) UY29266A1 (es)
WO (1) WO2006066079A2 (es)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2589527A1 (en) 2004-12-17 2006-06-22 Anadys Pharmaceuticals, Inc. Pyridazinone compounds
EA015252B1 (ru) 2005-05-10 2011-06-30 Интермьюн, Инк. Способ модуляции стресс-активированной протеинкиназной системы
US20080090814A1 (en) * 2006-06-22 2008-04-17 Anadys Pharmaceuticals, Inc. Pyridazinone compounds
EP2038286B1 (en) 2006-06-22 2017-03-08 Anadys Pharmaceuticals, Inc. Pyrro[1,2-b]pyridazinone compounds
WO2008073987A1 (en) * 2006-12-12 2008-06-19 Anadys Pharmaceuticals, Inc. Saturated fused [1,2-b] pyridazinone compounds
CL2007003587A1 (es) 2006-12-12 2008-07-04 Anadys Pharmaceuticals Inc Compuestos derivados de pirimidinas sustituidas; composicion farmaceutica que comprende a dichos compuestos y otro agente activo; y su uso para tratar o prevenir la infeccion de la hepatitis c.
US20080188466A1 (en) * 2006-12-21 2008-08-07 Anadys Pharmaceuticals, Inc. Pyridazinone compounds
US20080275032A1 (en) * 2006-12-29 2008-11-06 Yuefen Zhou Pyridazinone compounds
US20080227774A1 (en) * 2007-03-15 2008-09-18 Frank Ruebsam 5,5-disubstituted-indolizinone compounds
UA100120C2 (en) * 2007-04-03 2012-11-26 Анадис Фармасьютикалз, Инк. 5,6-dihydro-1h-pyridin-2-one compounds
ATE548044T1 (de) 2007-05-04 2012-03-15 Vertex Pharma Kombinationstherapie zur behandlung von hiv- infektionen
US20080292588A1 (en) * 2007-05-17 2008-11-27 Anadys Pharmaceuticals, Inc. 1-methyl-benzo[1,2,4]thiadiazine 1-oxide derivatives
ITMI20071012A1 (it) * 2007-05-18 2008-11-19 St Microelectronics Srl Dispositivo di memoria migliorato a veloce programmazione
US7834009B2 (en) * 2007-08-27 2010-11-16 Anadys Pharmaceuticals, Inc. 4-hydroxy-5,6-dihydro-1H-pyridin-2-one compounds
CN102099036B (zh) 2008-06-03 2015-05-27 英特芒尼公司 用于治疗炎性疾患和纤维化疾患的化合物和方法
TWI438206B (zh) * 2008-06-10 2014-05-21 Anadys Pharmaceuticals Inc 〔１，２，４〕噻二１，１二氧化物化合物
TWI480272B (zh) 2008-10-09 2015-04-11 Anadys Pharmaceuticals Inc 藉由５，６－二氫－１ｈ－吡啶－２－酮與一或多種其他抗病毒化合物的組合物抑制ｃ型肝炎病毒的方法
TW201026675A (en) * 2008-10-09 2010-07-16 Anadys Pharmaceuticals Inc 5,6-dihydro-1H-pyridin-2-one compounds
WO2010082050A1 (en) 2009-01-16 2010-07-22 Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. Macrocyclic and 7-aminoalkyl-substituted benzoxazocines for treatment of hepatitis c infections
WO2011045271A1 (de) 2009-10-15 2011-04-21 Bayer Cropscience Ag Herbizid wirksame heterocyclylsubstituierte pyridazinone
WO2011056647A1 (en) * 2009-10-28 2011-05-12 Anadys Pharmaceuticals, Inc. Deuterated 5,6-dihydro-1h-pyridin-2-one compounds
WO2011072370A1 (en) 2009-12-18 2011-06-23 Boehringer Ingelheim International Gmbh Hcv combination therapy
US20120321590A1 (en) 2011-04-06 2012-12-20 Anadys Pharmaceuticals, Inc. Bridged polycyclic compounds
AR092742A1 (es) 2012-10-02 2015-04-29 Intermune Inc Piridinonas antifibroticas
WO2014121417A1 (en) 2013-02-07 2014-08-14 Merck Sharp & Dohme Corp. Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
WO2014121416A1 (en) 2013-02-07 2014-08-14 Merck Sharp & Dohme Corp. Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
WO2014121418A1 (en) 2013-02-07 2014-08-14 Merck Sharp & Dohme Corp. Tetracyclic heterocycle compounds and methods of use thereof for the treatment of hepatitis c
CN110452216B (zh) 2014-04-02 2022-08-26 英特穆恩公司 抗纤维化吡啶酮类
UA126056C2 (uk) * 2014-04-29 2022-08-10 ЕфЕмСі КОРПОРЕЙШН Піридазинонові гербіциди
WO2017098952A1 (ja) * 2015-12-07 2017-06-15 Dic株式会社 重合性化合物の製造方法
CN105999097A (zh) * 2016-07-08 2016-10-12 王恩禄 一种治疗乙肝的中药组合物

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5954047A (en) * 1997-10-17 1999-09-21 Systemic Pulmonary Development, Ltd. Methods and apparatus for delivering aerosolized medication
US20040034041A1 (en) 2000-05-10 2004-02-19 Dashyant Dhanak Novel anti-infectives
US20060003346A1 (en) 2000-08-11 2006-01-05 Ashok Amin Method for treating hepatitis
AR036081A1 (es) 2001-06-07 2004-08-11 Smithkline Beecham Corp Compuesto de 1,2-dihidroquinolina, su uso para preparar una composicion farmaceutica, metodos para prepararlo y compuestos del acido 2-aminobenzoico n-alquilado de utilidad como intermediarios en dichos metodos
WO2003059356A2 (en) 2001-10-30 2003-07-24 Smithkline Beecham Corporation Novel anti-infectives
US7601709B2 (en) 2003-02-07 2009-10-13 Enanta Pharmaceuticals, Inc. Macrocyclic hepatitis C serine protease inhibitors
US7439246B2 (en) 2004-06-28 2008-10-21 Bristol-Myers Squibb Company Fused heterocyclic kinase inhibitors
EP1786807B1 (en) 2004-08-23 2009-07-29 F.Hoffmann-La Roche Ag Heterocyclic antiviral compounds
CA2589527A1 (en) 2004-12-17 2006-06-22 Anadys Pharmaceuticals, Inc. Pyridazinone compounds
RU2007143049A (ru) 2005-04-21 2009-05-27 Ниппон Синяку Ко., Лтд. (Jp) Производное фталазинона и содержащая его фармацевтическая композиция
CN101189230A (zh) 2005-05-04 2008-05-28 弗·哈夫曼-拉罗切有限公司 抗病毒的杂环化合物
EP2038286B1 (en) 2006-06-22 2017-03-08 Anadys Pharmaceuticals, Inc. Pyrro[1,2-b]pyridazinone compounds

Also Published As

Publication number Publication date
KR20070100743A (ko) 2007-10-11
EA200701297A1 (ru) 2007-12-28
SV2006002347A (es) 2006-08-25
CN101137651A (zh) 2008-03-05
PE20060871A1 (es) 2006-09-04
AU2005316396A1 (en) 2006-06-22
NO20073105L (no) 2007-09-13
WO2006066079A3 (en) 2006-12-14
EP1824847A2 (en) 2007-08-29
GT200500373A (es) 2006-10-02
UY29266A1 (es) 2006-07-31
MX2007007264A (es) 2007-08-14
US7425552B2 (en) 2008-09-16
CA2589527A1 (en) 2006-06-22
AP2007004040A0 (en) 2007-06-30
US20060189602A1 (en) 2006-08-24
WO2006066079A2 (en) 2006-06-22
AR054214A1 (es) 2007-06-13
IL183510A0 (en) 2007-09-20
TW200635596A (en) 2006-10-16
JP2008526687A (ja) 2008-07-24
CR9204A (es) 2007-09-06

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