PA8733401A1 - Compuestos de pirro[1,2-b]piridazinona - Google Patents

Compuestos de pirro[1,2-b]piridazinona

Info

Publication number
PA8733401A1
PA8733401A1 PA20078733401A PA8733401A PA8733401A1 PA 8733401 A1 PA8733401 A1 PA 8733401A1 PA 20078733401 A PA20078733401 A PA 20078733401A PA 8733401 A PA8733401 A PA 8733401A PA 8733401 A1 PA8733401 A1 PA 8733401A1
Authority
PA
Panama
Prior art keywords
compounds
pirro
piridazinona
piridazinone
infections
Prior art date
Application number
PA20078733401A
Other languages
English (en)
Inventor
E Webber Stephen
Li Liansheng
Ruebsam Frank
T Tran Martin
E Murphy Douglas
Kucera David
Sun Zhongxiang
Viet Tran Chinh
Original Assignee
Anadys Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anadys Pharmaceuticals Inc filed Critical Anadys Pharmaceuticals Inc
Publication of PA8733401A1 publication Critical patent/PA8733401A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/541—Non-condensed thiazines containing further heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA INVENCIÓN ESTÁ DIRIGIDA A LOS COMPUESTOS DE PIRRO[1,2-b]PIRIDAZINONA Y A LAS COMPOSICIONES FARMACÉUTICAS QUE CONTIENEN TALES COMPUESTOS, QUE SON ÚTILES EN EL TRATAMIENTO DE INFECCIONES POR EL VIRUS DE LA HEPATITIS C.
PA20078733401A 2006-06-22 2007-06-22 Compuestos de pirro[1,2-b]piridazinona PA8733401A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US81557806P 2006-06-22 2006-06-22

Publications (1)

Publication Number Publication Date
PA8733401A1 true PA8733401A1 (es) 2008-11-19

Family

ID=38833773

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20078733401A PA8733401A1 (es) 2006-06-22 2007-06-22 Compuestos de pirro[1,2-b]piridazinona

Country Status (14)

Country Link
US (3) US7462611B2 (es)
EP (1) EP2038286B1 (es)
JP (2) JP5306194B2 (es)
KR (1) KR101384266B1 (es)
CN (2) CN101501039B (es)
AR (1) AR061581A1 (es)
BR (1) BRPI0713684A2 (es)
CA (1) CA2656000C (es)
IL (1) IL196106A0 (es)
MX (1) MX2008016519A (es)
NZ (1) NZ573875A (es)
PA (1) PA8733401A1 (es)
TW (1) TWI395749B (es)
WO (1) WO2007150001A1 (es)

Families Citing this family (18)

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AP2007004040A0 (en) 2004-12-17 2007-06-30 Anadys Pharmaceuticals Inc Pyridazinone compounds
WO2007150001A1 (en) * 2006-06-22 2007-12-27 Anadys Pharmaceuticals, Inc. Pyrro[1,2-b]pyridazinone compounds
UA100120C2 (en) * 2007-04-03 2012-11-26 Анадис Фармасьютикалз, Инк. 5,6-dihydro-1h-pyridin-2-one compounds
ES2381410T3 (es) 2007-05-04 2012-05-28 Vertex Pharmceuticals Incorporated Terapia de combinación paa el tratamiento de infecciones por VHC
ES2546213T3 (es) 2008-03-03 2015-09-21 Novartis Ag Compuestos y composiciones como moduladores de la actividad de TLR
AU2009241514A1 (en) * 2008-04-15 2009-11-05 Intermune, Inc. Novel inhibitors of hepatitis C virus replication
ES2435799T3 (es) 2008-10-09 2013-12-23 Anadys Pharmaceuticals, Inc. Un método de inhibición del virus de la hepatitis C mediante combinación de una 5,6-dihidro-1H-piridin-2-ona y de uno o más compuestos antivirales adicionales
EP2493476A4 (en) 2009-10-28 2013-06-19 Anadys Pharmaceuticals Inc DEUTERATED 5,6-DIHYDRO-1H-PYRIDINE-2-ON COMPOUNDS
CN102596201A (zh) 2009-10-30 2012-07-18 贝林格尔.英格海姆国际有限公司 包含BI201335、干扰素α和利巴韦林的HCV组合治疗的用药方案
TW201121968A (en) * 2009-11-09 2011-07-01 Intermune Inc Novel inhibitors of hepatitis C virus replication
KR20120116404A (ko) * 2009-12-18 2012-10-22 베링거 인겔하임 인터내셔날 게엠베하 Ｈｃｖ 병용 요법
US20120321590A1 (en) 2011-04-06 2012-12-20 Anadys Pharmaceuticals, Inc. Bridged polycyclic compounds
JP6010614B2 (ja) 2011-06-07 2016-10-19 アナディス ファーマシューティカルズ インク 血清尿酸を低下させるための［１，２，４］チアジアジン１，１−ジオキサイド化合物
KR102017867B1 (ko) 2011-06-23 2019-09-03 다이나믹 마이크로시스템즈 세미컨덕터 이큅먼트 게엠베하 반도체 클리너 시스템들 및 방법들
CN102796105B (zh) * 2012-08-15 2014-08-06 苏州施亚生物科技有限公司 2,5,6,7-四氢吡咯并[3,4-c]哒嗪-3-酮及其衍生物以及它们的合成方法
EA201591333A1 (ru) * 2013-01-14 2015-11-30 Ф. Хоффманн-Ля Рош Аг Новый способ получения метилового эфира n-(4-нитро-2-сульфамоилфенил)малонаминовой кислоты и метилового эфира n-(4-амино-2-сульфамоилфенил)малонаминовой кислоты
CN103553986B (zh) * 2013-11-19 2015-04-22 郑州西格玛化工有限公司 一种制备3,4-二氨基苯磺酰胺的方法
WO2021030278A1 (en) * 2019-08-12 2021-02-18 Aligos Therapeutics, Inc. Bicyclic compounds

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Also Published As

Publication number Publication date
US20090105473A1 (en) 2009-04-23
CA2656000A1 (en) 2007-12-27
MX2008016519A (es) 2009-01-30
KR20090063203A (ko) 2009-06-17
JP5306194B2 (ja) 2013-10-02
AU2007260827A1 (en) 2007-12-27
AR061581A1 (es) 2008-09-03
WO2007150001A1 (en) 2007-12-27
US7582754B2 (en) 2009-09-01
CN101501039A (zh) 2009-08-05
TWI395749B (zh) 2013-05-11
JP5670487B2 (ja) 2015-02-18
JP2009544575A (ja) 2009-12-17
CN101501039B (zh) 2012-02-22
NZ573875A (en) 2011-11-25
IL196106A0 (en) 2009-09-01
CA2656000C (en) 2016-09-06
EP2038286B1 (en) 2017-03-08
US20080031852A1 (en) 2008-02-07
JP2013136599A (ja) 2013-07-11
BRPI0713684A2 (pt) 2012-10-30
US7842838B2 (en) 2010-11-30
EP2038286A4 (en) 2010-05-12
EP2038286A1 (en) 2009-03-25
US7462611B2 (en) 2008-12-09
US20090312570A1 (en) 2009-12-17
CN102584649A (zh) 2012-07-18
KR101384266B1 (ko) 2014-04-24
TW200817405A (en) 2008-04-16
WO2007150001A8 (en) 2008-02-28

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