PA8516201A1 - Derivados de pirrol - Google Patents
Derivados de pirrolInfo
- Publication number
- PA8516201A1 PA8516201A1 PA20018516201A PA8516201A PA8516201A1 PA 8516201 A1 PA8516201 A1 PA 8516201A1 PA 20018516201 A PA20018516201 A PA 20018516201A PA 8516201 A PA8516201 A PA 8516201A PA 8516201 A1 PA8516201 A1 PA 8516201A1
- Authority
- PA
- Panama
- Prior art keywords
- rent
- hydrogen
- compounds
- arilo
- aryl
- Prior art date
Links
- KAESVJOAVNADME-UHFFFAOYSA-N Pyrrole Chemical class C=1C=CNC=1 KAESVJOAVNADME-UHFFFAOYSA-N 0.000 title abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical group [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 abstract 6
- 239000001257 hydrogen Substances 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 4
- -1 CARBOXYL Chemical class 0.000 abstract 3
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- XFXPMWWXUTWYJX-UHFFFAOYSA-N Cyanide Chemical class N#[C-] XFXPMWWXUTWYJX-UHFFFAOYSA-N 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
- 230000003612 virological effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Virology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0016453.3A GB0016453D0 (en) | 2000-07-04 | 2000-07-04 | Pyrrole derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PA8516201A1 true PA8516201A1 (es) | 2002-07-30 |
Family
ID=9895031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PA20018516201A PA8516201A1 (es) | 2000-07-04 | 2001-05-04 | Derivados de pirrol |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6737429B2 (enExample) |
| EP (1) | EP1301481A1 (enExample) |
| JP (1) | JP2004502674A (enExample) |
| KR (1) | KR100549884B1 (enExample) |
| CN (1) | CN1440385A (enExample) |
| AR (1) | AR028602A1 (enExample) |
| AU (2) | AU2001263874B2 (enExample) |
| BR (1) | BR0112241A (enExample) |
| CA (1) | CA2412270A1 (enExample) |
| EC (1) | ECSP014109A (enExample) |
| GB (1) | GB0016453D0 (enExample) |
| GT (1) | GT200100111A (enExample) |
| MX (1) | MXPA02012409A (enExample) |
| PA (1) | PA8516201A1 (enExample) |
| PE (1) | PE20020269A1 (enExample) |
| UY (1) | UY26720A1 (enExample) |
| WO (1) | WO2002002524A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1405849A1 (en) * | 2002-10-04 | 2004-04-07 | Corning Incorporated | Halogenated styrene compounds and low-absorption-loss polymers obtainable therefrom |
| US7569536B2 (en) * | 2003-12-26 | 2009-08-04 | Masatoshi Hagiwara | Method for controlling SR protein phosphorylation, and antiviral agents whose active ingredients comprise agents that control SR protein activity |
| KR101178747B1 (ko) | 2004-09-30 | 2012-09-03 | 다케다 야쿠힌 고교 가부시키가이샤 | 프로톤 펌프 저해제 |
| TW200628446A (en) * | 2004-12-14 | 2006-08-16 | Takeda Pharmaceuticals Co | Substituted pyrrole derivative |
| WO2006072833A1 (en) * | 2005-01-06 | 2006-07-13 | Pfizer Limited | Imidazole derivatives as enzyme reverse transcriptase modulators |
| PE20070540A1 (es) | 2005-08-30 | 2007-06-26 | Takeda Pharmaceutical | Derivados de pirrol como inhibidores de la secrecion acida |
| CA2665007A1 (en) * | 2006-10-06 | 2008-05-08 | Merck & Co., Inc. | Non-nucleoside reverse transcriptase inhibitors |
| CN101677977A (zh) * | 2006-11-10 | 2010-03-24 | 欣达克斯制药公司 | 用于治疗癌症的ERα+配体和组蛋白脱乙酰化酶抑制剂组合 |
| US8933105B2 (en) | 2007-02-28 | 2015-01-13 | Takeda Pharmaceutical Company Limited | Pyrrole compounds |
| WO2009015180A2 (en) * | 2007-07-23 | 2009-01-29 | Syndax Pharmaceuticals, Inc. | Novel compounds and methods of using them |
| SG185313A1 (en) * | 2007-10-16 | 2012-11-29 | Nikon Corp | Illumination optical system, exposure apparatus, and device manufacturing method |
| US20090131367A1 (en) * | 2007-11-19 | 2009-05-21 | The Regents Of The University Of Colorado | Combinations of HDAC Inhibitors and Proteasome Inhibitors |
| UA105185C2 (uk) | 2008-08-27 | 2014-04-25 | Такеда Фармасьютікал Компані Лімітед | Піроли |
| GB0823001D0 (en) * | 2008-12-17 | 2009-01-28 | Syngenta Participations Ag | Thiophene,furan and pyrrole derivatives with plant growth regulating properties |
| CN101775011B (zh) * | 2009-01-13 | 2013-07-31 | 中国人民解放军军事医学科学院毒物药物研究所 | N-取代苯基-3-甲烯杂环芳烃-2,5-二甲基吡咯类化合物及其抗hiv/aids的应用 |
| US20230058961A1 (en) * | 2019-11-19 | 2023-02-23 | New York Blood Center, Inc. | Substituted heterocyclics with therapeutic activity in hiv |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3644631A (en) * | 1969-05-13 | 1972-02-22 | Endo Lab | Therapeutic methods utilizing aryl pyrrol-3-yl ketones |
| US4282242A (en) * | 1980-03-07 | 1981-08-04 | Pfizer Inc. | Antidiabetic pyrrolecarboxylic acids |
| US4347186A (en) * | 1980-10-20 | 1982-08-31 | Syntex (U.S.A.) Inc. | Process for preparing 5-aroyl 1,2-dihydro-3-H pyrrolo[1,2-a]pyrrole-1-carboxylic acids and novel intermediates therein |
| RU2130453C1 (ru) * | 1992-12-17 | 1999-05-20 | Пфайзер Инк. | Замещенные пиразолы, фармацевтическая композиция на их основе, способ лечения, промежуточный продукт |
| FI964893A7 (fi) * | 1994-06-06 | 1996-12-05 | Pfizer | Substituoituja pyratsoleja, jotka ovat aktiivisia kortikotropiinin vap auttamistekijän (CRF) antagonisteina |
| TW406075B (en) * | 1994-12-13 | 2000-09-21 | Upjohn Co | Alkyl substituted piperidinyl and piperazinyl anti-AIDS compounds |
| EP0912548A1 (en) * | 1996-07-11 | 1999-05-06 | Pfizer Inc. | Pyridylpyrrole compounds useful as interleukin- and tnf antagonists |
| DE19963174A1 (de) * | 1999-12-27 | 2001-07-12 | Gruenenthal Gmbh | Substituierte Pyrrol-Mannichbasen |
-
2000
- 2000-07-04 GB GBGB0016453.3A patent/GB0016453D0/en not_active Ceased
-
2001
- 2001-04-30 WO PCT/EP2001/004832 patent/WO2002002524A1/en not_active Ceased
- 2001-04-30 AU AU2001263874A patent/AU2001263874B2/en not_active Ceased
- 2001-04-30 JP JP2002507781A patent/JP2004502674A/ja active Pending
- 2001-04-30 AU AU6387401A patent/AU6387401A/xx active Pending
- 2001-04-30 EP EP01938137A patent/EP1301481A1/en not_active Withdrawn
- 2001-04-30 CA CA002412270A patent/CA2412270A1/en not_active Abandoned
- 2001-04-30 BR BR0112241-0A patent/BR0112241A/pt not_active IP Right Cessation
- 2001-04-30 KR KR1020037000138A patent/KR100549884B1/ko not_active Expired - Fee Related
- 2001-04-30 MX MXPA02012409A patent/MXPA02012409A/es active IP Right Grant
- 2001-04-30 CN CN01812290A patent/CN1440385A/zh active Pending
- 2001-05-04 PA PA20018516201A patent/PA8516201A1/es unknown
- 2001-05-18 UY UY26720A patent/UY26720A1/es not_active Application Discontinuation
- 2001-05-22 AR ARP010102414A patent/AR028602A1/es not_active Application Discontinuation
- 2001-05-25 PE PE2001000487A patent/PE20020269A1/es not_active Application Discontinuation
- 2001-06-12 GT GT200100111A patent/GT200100111A/es unknown
- 2001-06-13 US US09/880,534 patent/US6737429B2/en not_active Expired - Fee Related
- 2001-07-04 EC EC2001004109A patent/ECSP014109A/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR028602A1 (es) | 2003-05-14 |
| US20020032221A1 (en) | 2002-03-14 |
| AU6387401A (en) | 2002-01-14 |
| KR100549884B1 (ko) | 2006-02-06 |
| MXPA02012409A (es) | 2003-04-25 |
| GT200100111A (es) | 2002-03-18 |
| ECSP014109A (es) | 2002-02-25 |
| GB0016453D0 (en) | 2000-08-23 |
| BR0112241A (pt) | 2003-06-24 |
| EP1301481A1 (en) | 2003-04-16 |
| PE20020269A1 (es) | 2002-04-08 |
| CN1440385A (zh) | 2003-09-03 |
| JP2004502674A (ja) | 2004-01-29 |
| AU2001263874B2 (en) | 2006-10-19 |
| UY26720A1 (es) | 2001-11-30 |
| US6737429B2 (en) | 2004-05-18 |
| CA2412270A1 (en) | 2002-01-10 |
| WO2002002524A1 (en) | 2002-01-10 |
| KR20030014321A (ko) | 2003-02-15 |
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