OA13338A - 3-cycloalkylaminopyrrolidine derivates as modulators of chemokine receptors. - Google Patents
3-cycloalkylaminopyrrolidine derivates as modulators of chemokine receptors. Download PDFInfo
- Publication number
- OA13338A OA13338A OA1200600195A OA1200600195A OA13338A OA 13338 A OA13338 A OA 13338A OA 1200600195 A OA1200600195 A OA 1200600195A OA 1200600195 A OA1200600195 A OA 1200600195A OA 13338 A OA13338 A OA 13338A
- Authority
- OA
- OAPI
- Prior art keywords
- amino
- trifluoromethyl
- mono
- pyrrolidin
- pyridin
- Prior art date
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D277/24—Radicals substituted by oxygen atoms
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- A61K31/4965—Non-condensed pyrazines
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- A61K31/50—Pyridazines; Hydrogenated pyridazines
- A61K31/501—Pyridazines; Hydrogenated pyridazines not condensed and containing further heterocyclic rings
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- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Obesity (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Child & Adolescent Psychology (AREA)
- Urology & Nephrology (AREA)
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Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US53127003P | 2003-12-18 | 2003-12-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
OA13338A true OA13338A (en) | 2007-04-13 |
Family
ID=34710216
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
OA1200600195A OA13338A (en) | 2003-12-18 | 2004-12-16 | 3-cycloalkylaminopyrrolidine derivates as modulators of chemokine receptors. |
Country Status (28)
Country | Link |
---|---|
US (5) | US7576089B2 (zh) |
EP (1) | EP1696919B1 (zh) |
JP (1) | JP4740151B2 (zh) |
KR (2) | KR20080052683A (zh) |
CN (2) | CN102344398B (zh) |
AP (1) | AP2439A (zh) |
AU (1) | AU2004305079B2 (zh) |
BR (1) | BRPI0417605B8 (zh) |
CA (1) | CA2550596C (zh) |
CR (1) | CR8455A (zh) |
DK (1) | DK1696919T3 (zh) |
EA (1) | EA013631B1 (zh) |
EC (1) | ECSP066615A (zh) |
ES (1) | ES2439894T3 (zh) |
GE (1) | GEP20084505B (zh) |
HK (1) | HK1166321A1 (zh) |
IL (1) | IL175953A (zh) |
IS (1) | IS2956B (zh) |
MA (1) | MA28391B1 (zh) |
MX (1) | MXPA06007000A (zh) |
NI (1) | NI200600136A (zh) |
NO (1) | NO336486B1 (zh) |
NZ (1) | NZ547316A (zh) |
OA (1) | OA13338A (zh) |
TN (1) | TNSN06188A1 (zh) |
UA (1) | UA82917C2 (zh) |
WO (1) | WO2005060665A2 (zh) |
ZA (1) | ZA200604875B (zh) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU230612B1 (hu) * | 2002-11-27 | 2017-04-28 | Incyte Corporation | Kemokin receptorokat módosító hatású 3-aminopirrolidin-származékok |
MXPA06011722A (es) * | 2004-04-13 | 2007-01-25 | Incyte Corp | Derivados de piperazinilpiperidina como antagonistas del receptor de quimiocina. |
GEP20084519B (en) | 2004-05-11 | 2008-10-27 | Incyte Corp | 3-(4-heteroarylcyclo-hexylamino) cyclopenta-necarboxamides as modulators of chemokine receptors |
EP1763351B9 (en) | 2004-06-28 | 2017-05-31 | Incyte Holdings Corporation | 3-aminocyclopentanecarboxamides as modulators of chemokine receptors |
JP4116671B2 (ja) | 2004-06-28 | 2008-07-09 | インサイト コーポレイション | ケモカイン受容体の調節剤としての3−アミノシクロペンタンカルボキサミド |
KR20080044360A (ko) * | 2004-07-30 | 2008-05-20 | 화이자 프로덕츠 인코포레이티드 | Ccr2 매개 질병 또는 장애의 치료방법 |
WO2006029173A2 (en) * | 2004-09-08 | 2006-03-16 | Boys Town National Research Hospital | Treatment of glomerular basement membrane disease involving matrix metalloproteinase-12 |
EP2269610A3 (en) | 2004-09-20 | 2011-03-09 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors |
MX2007003327A (es) | 2004-09-20 | 2007-06-05 | Xenon Pharmaceuticals Inc | Derivados heterociclicos, y su uso como mediadores de estearoil-coa desaturasa. |
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