OA12513A - Novel composition and use. - Google Patents
Novel composition and use. Download PDFInfo
- Publication number
- OA12513A OA12513A OA1200200145A OA1200200145A OA12513A OA 12513 A OA12513 A OA 12513A OA 1200200145 A OA1200200145 A OA 1200200145A OA 1200200145 A OA1200200145 A OA 1200200145A OA 12513 A OA12513 A OA 12513A
- Authority
- OA
- OAPI
- Prior art keywords
- composition according
- thiazolidinedione
- carrier
- compound
- composition
- Prior art date
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- 239000000203 mixture Substances 0.000 title claims description 128
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- 150000001875 compounds Chemical class 0.000 claims abstract description 116
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Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
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- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
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- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
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- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
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- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
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- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9927119.9A GB9927119D0 (en) | 1999-11-16 | 1999-11-16 | Novel composition and use |
| GBGB9927120.7A GB9927120D0 (en) | 1999-11-16 | 1999-11-16 | Novel composition and use |
| GB0013236A GB0013236D0 (en) | 2000-05-31 | 2000-05-31 | Novel composition and use |
| GB0013240A GB0013240D0 (en) | 2000-05-31 | 2000-05-31 | Novel composition and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA12513A true OA12513A (en) | 2006-05-29 |
Family
ID=27447849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA1200200145A OA12513A (en) | 1999-11-16 | 2000-11-16 | Novel composition and use. |
Country Status (40)
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| EP (3) | EP1913945A3 (cs) |
| JP (2) | JP4865975B2 (cs) |
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| CN (1) | CN1222290C (cs) |
| AP (1) | AP1389A (cs) |
| AR (2) | AR030920A1 (cs) |
| AT (1) | ATE292466T1 (cs) |
| AU (3) | AU775654B2 (cs) |
| BG (1) | BG65616B1 (cs) |
| BR (1) | BR0015605A (cs) |
| CA (1) | CA2388846A1 (cs) |
| CO (1) | CO5300392A1 (cs) |
| CZ (1) | CZ302500B6 (cs) |
| DE (1) | DE60019329T2 (cs) |
| DK (1) | DK1231918T3 (cs) |
| DZ (1) | DZ3251A1 (cs) |
| EA (1) | EA004878B1 (cs) |
| ES (1) | ES2240199T3 (cs) |
| HK (1) | HK1049788B (cs) |
| HR (1) | HRP20020416B1 (cs) |
| HU (1) | HU229960B1 (cs) |
| IL (3) | IL149618A0 (cs) |
| MA (1) | MA25567A1 (cs) |
| ME (1) | ME00318B (cs) |
| MX (1) | MXPA02005005A (cs) |
| MY (1) | MY125516A (cs) |
| NO (1) | NO329926B1 (cs) |
| NZ (1) | NZ518946A (cs) |
| OA (1) | OA12513A (cs) |
| PE (1) | PE20011011A1 (cs) |
| PL (1) | PL200943B1 (cs) |
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| UA (1) | UA73150C2 (cs) |
| UY (1) | UY26439A1 (cs) |
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| CA2407713A1 (en) * | 2000-05-01 | 2001-11-08 | Aeropharm Technology, Inc. | A core formulation |
| CA2453782A1 (en) * | 2001-07-10 | 2003-01-23 | Kos Life Sciences, Inc. | Core formulation comprising troglitazone and a biguanide |
| GB0203296D0 (en) * | 2002-02-12 | 2002-03-27 | Glaxo Group Ltd | Novel composition |
| AU2002356419A1 (en) * | 2002-06-17 | 2003-12-31 | Themis Laboratories Private Limited | Multilayer tablets containing thiazolidinedione and biguanides and methods for producing them |
| CA2492722A1 (en) * | 2002-07-11 | 2004-01-22 | Takeda Pharmaceutical Company Limited | Production method of coated preparations |
| US8637512B2 (en) * | 2002-07-29 | 2014-01-28 | Glaxo Group Limited | Formulations and method of treatment |
| US7785627B2 (en) * | 2002-09-20 | 2010-08-31 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US8084058B2 (en) | 2002-09-20 | 2011-12-27 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| CA2499597C (en) * | 2002-09-20 | 2012-01-17 | Unchalee Kositprapa | Multistage formulation containing a biguanide and thiazolidindione derivatives |
| US9060941B2 (en) | 2002-09-20 | 2015-06-23 | Actavis, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| US7959946B2 (en) | 2002-09-20 | 2011-06-14 | Watson Pharmaceuticals, Inc. | Pharmaceutical formulation containing a biguanide and a thiazolidinedione derivative |
| UA80991C2 (en) * | 2002-10-07 | 2007-11-26 | Solid preparation containing an insulin resistance improving drug and an active ingredient useful as a remedy for diabetes | |
| KR101114808B1 (ko) | 2003-01-29 | 2012-02-15 | 다케다 야쿠힌 고교 가부시키가이샤 | 피복 제제의 제조법 |
| FR2858556B1 (fr) * | 2003-08-06 | 2006-03-10 | Galenix Innovations | Composition pharmaceutique solide dispersible et/ou orodispersible non pelliculee contenant au moins le principe actif metformine, et procede de preparation |
| EP1738754B1 (en) | 2004-04-14 | 2015-07-15 | Takeda Pharmaceutical Company Limited | Solid pharmaceutical preparation |
| WO2006011397A1 (ja) * | 2004-07-27 | 2006-02-02 | Kowa Company., Ltd. | 糖尿病の予防または治療のための薬剤 |
| KR20080007371A (ko) * | 2005-04-26 | 2008-01-18 | 다이닛본 스미토모 세이야꾸 가부시끼가이샤 | 비구아니드 화합물 함유 과립성 제제 |
| WO2007072992A2 (en) * | 2005-12-22 | 2007-06-28 | Takeda Pharmaceutical Company Limited | Solid preparation containing an insulin sensitizer |
| FR2896159B1 (fr) | 2006-01-13 | 2008-09-12 | Merck Sante Soc Par Actions Si | Combinaison de derives de triazine et d'agents sensibilisateurs a l'insuline. |
| JP4893750B2 (ja) | 2006-12-26 | 2012-03-07 | 富士通株式会社 | データ圧縮装置およびデータ復元装置 |
| ATE488227T1 (de) | 2007-02-01 | 2010-12-15 | Takeda Pharmaceutical | Feste zubereitung mit alogliptin und pioglitazon |
| JP5467870B2 (ja) | 2007-02-09 | 2014-04-09 | アルファファーム ピーティーワイ リミテッド | 異なる物理的形態の２種以上の有効医薬成分を含有する投薬形態 |
| TR200803177A2 (tr) * | 2008-05-06 | 2009-11-23 | Bi̇li̇m İlaç Sanayi̇ Ti̇caret A.Ş. | Antihiperglisemik etkili metformîn - pioglitazon formülasyonu. |
| US8846315B2 (en) | 2008-08-12 | 2014-09-30 | Zinfandel Pharmaceuticals, Inc. | Disease risk factors and methods of use |
| PL2324126T3 (pl) | 2008-08-12 | 2014-09-30 | Zinfandel Pharmaceuticals Inc | Sposób identyfikacji czynników ryzyka choroby Alzheimera |
| FR2951945B1 (fr) * | 2009-11-05 | 2013-08-09 | Sanofi Aventis | Composition pharmaceutique |
| BR112012011726A2 (pt) * | 2009-11-13 | 2020-05-19 | Bristol-Myers Squibb Company | comprimidos de duas camadas, seu uso, e suas combinações farmacêuticas |
| EP2441442A1 (en) | 2010-10-08 | 2012-04-18 | LEK Pharmaceuticals d.d. | A pharmaceutical composition comprising a thiazolidinedione |
| US11759441B2 (en) | 2011-01-07 | 2023-09-19 | Anji Pharmaceuticals Inc. | Biguanide compositions and methods of treating metabolic disorders |
| US9572784B2 (en) | 2011-01-07 | 2017-02-21 | Elcelyx Therapeutics, Inc. | Compositions comprising statins, biguanides and further agents for reducing cardiometabolic risk |
| US9480663B2 (en) | 2011-01-07 | 2016-11-01 | Elcelyx Therapeutics, Inc. | Biguanide compositions and methods of treating metabolic disorders |
| US8796338B2 (en) | 2011-01-07 | 2014-08-05 | Elcelyx Therapeutics, Inc | Biguanide compositions and methods of treating metabolic disorders |
| US11974971B2 (en) | 2011-01-07 | 2024-05-07 | Anji Pharmaceuticals Inc. | Compositions and methods for treating metabolic disorders |
| CA2823397C (en) | 2011-01-07 | 2020-03-10 | Elcelyx Therapeutics, Inc. | Chemosensory receptor ligand-based therapies |
| US9211263B2 (en) | 2012-01-06 | 2015-12-15 | Elcelyx Therapeutics, Inc. | Compositions and methods of treating metabolic disorders |
| SG191399A1 (en) | 2011-01-10 | 2013-08-30 | Zinfandel Pharmaceuticals Inc | Methods and drug products for treating alzheimer's disease |
| MX379226B (es) | 2012-01-06 | 2025-03-11 | Anji Pharma Us Llc | Composiciones y métodos para tratar trastornos metabólicos. |
| CN104254325A (zh) | 2012-01-06 | 2014-12-31 | 埃尔舍利克斯治疗公司 | 双胍组合物和治疗代谢性病症的方法 |
| CN108451923B (zh) * | 2018-05-31 | 2025-05-06 | 常州兰陵制药有限公司 | 盐酸二甲双胍速释胶囊及其制备方法 |
| JP2023528726A (ja) | 2020-04-01 | 2023-07-06 | ハンジョウ ジョンメイ フアドン ファーマシューティカル シーオー．，エルティーディー． | Ｇｌｐ１ｒアゴニスト遊離塩基の薬学的に許容される酸塩類およびその調製法 |
| JP2023528565A (ja) | 2020-04-01 | 2023-07-05 | ハンジョウ ジョンメイ フアドン ファーマシューティカル シーオー．，エルティーディー． | Ｇｌｐ－１受容体アゴニストの結晶形ａおよびその調製法 |
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| JPS4613596Y1 (cs) * | 1969-06-02 | 1971-05-14 | ||
| DE2347531A1 (de) * | 1973-09-21 | 1975-04-30 | Hoechst Ag | Arzneizubereitungen zur oralen diabetes-behandlung |
| DE3856378T2 (de) * | 1987-09-04 | 2000-05-11 | Beecham Group P.L.C., Brentford | Substituierte Thiazolidindionderivate |
| US4999226A (en) * | 1988-06-01 | 1991-03-12 | Merrell Dow Pharmaceuticals Inc. | Pharmaceutical compositions for piperidinoalkanol-ibuprofen combination |
| JPH0553521A (ja) | 1991-08-28 | 1993-03-05 | Mitsubishi Electric Corp | オートトラツキング型ｃｒｔデイスプレイモニタ |
| GB9218830D0 (en) * | 1992-09-05 | 1992-10-21 | Smithkline Beecham Plc | Novel compounds |
| IT1255522B (it) * | 1992-09-24 | 1995-11-09 | Ubaldo Conte | Compressa per impiego terapeutico atta a cedere una o piu' sostanze attive con differenti velocita' |
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2000
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