OA10855A - Nouveaux taxoïdes leur préparation et les compositions pharmaceutiques qui les contiennent - Google Patents

Nouveaux taxoïdes leur préparation et les compositions pharmaceutiques qui les contiennent Download PDF

Info

Publication number
OA10855A
OA10855A OA9800161A OA9800161A OA10855A OA 10855 A OA10855 A OA 10855A OA 9800161 A OA9800161 A OA 9800161A OA 9800161 A OA9800161 A OA 9800161A OA 10855 A OA10855 A OA 10855A
Authority
OA
OAPI
Prior art keywords
carbon atoms
radical
general formula
radicals
atoms
Prior art date
Application number
OA9800161A
Other languages
English (en)
French (fr)
Inventor
Herve Bouchard
Jean-Dominique Bourzat
Alain Commercon
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of OA10855A publication Critical patent/OA10855A/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/04Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/041,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/061,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
OA9800161A 1996-03-06 1998-09-04 Nouveaux taxoïdes leur préparation et les compositions pharmaceutiques qui les contiennent OA10855A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9602804A FR2745814B1 (fr) 1996-03-06 1996-03-06 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
OA10855A true OA10855A (fr) 2003-02-05

Family

ID=9489910

Family Applications (1)

Application Number Title Priority Date Filing Date
OA9800161A OA10855A (fr) 1996-03-06 1998-09-04 Nouveaux taxoïdes leur préparation et les compositions pharmaceutiques qui les contiennent

Country Status (34)

Country Link
US (1) US6160135A (ru)
EP (1) EP0885208B1 (ru)
JP (1) JP2000506158A (ru)
KR (1) KR19990087398A (ru)
CN (1) CN1210525A (ru)
AP (1) AP1023A (ru)
AT (1) ATE204266T1 (ru)
AU (1) AU715228B2 (ru)
BG (1) BG63693B1 (ru)
BR (1) BR9707887A (ru)
CA (1) CA2248195A1 (ru)
CZ (1) CZ283498A3 (ru)
DE (1) DE69706146T2 (ru)
DK (1) DK0885208T3 (ru)
EA (1) EA001516B1 (ru)
EE (1) EE03611B1 (ru)
ES (1) ES2161446T3 (ru)
FR (1) FR2745814B1 (ru)
GE (1) GEP20012517B (ru)
GR (1) GR3036410T3 (ru)
HU (1) HUP9902425A3 (ru)
IL (1) IL125998A (ru)
IS (1) IS4809A (ru)
NO (1) NO983472D0 (ru)
NZ (1) NZ331040A (ru)
OA (1) OA10855A (ru)
PL (1) PL328691A1 (ru)
PT (1) PT885208E (ru)
SK (1) SK121598A3 (ru)
TR (1) TR199801732T2 (ru)
TW (1) TW474928B (ru)
WO (1) WO1997032869A1 (ru)
YU (1) YU38398A (ru)
ZA (1) ZA971746B (ru)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5973160A (en) 1992-12-23 1999-10-26 Poss; Michael A. Methods for the preparation of novel sidechain-bearing taxanes
US6372780B2 (en) 1995-03-27 2002-04-16 Aventis Pharma S.A. Methods of treating cell lines expressing multidrug resistance P-glycoprotein
MA23823A1 (fr) 1995-03-27 1996-10-01 Aventis Pharma Sa Nouveaux taxoides, leur preparation et les compositions qui les contiennent
KR100551945B1 (ko) * 1997-12-19 2006-02-20 가부시키가이샤 야쿠루트 혼샤 택산 유도체
EP1020188A1 (en) * 1999-01-13 2000-07-19 Aventis Pharma S.A. New use of taxoid derivatives
CO5280224A1 (es) * 2000-02-02 2003-05-30 Univ Florida State Res Found Taxanos sustituidos con ester en c7, utiles como agentes antitumorales y composiciones farmaceuticas que los contienen
JP2003522171A (ja) 2000-02-02 2003-07-22 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド 抗腫瘍剤としてのc10カーボネート置換タキサン
FR2859996B1 (fr) * 2003-09-19 2006-02-03 Aventis Pharma Sa Solvat acetonique du dimethoxy docetaxel et son procede de preparation
CN1960721A (zh) 2004-03-05 2007-05-09 佛罗里达州立大学研究基金有限公司 C7乳酰氧基取代的紫杉烷类
US20110118473A1 (en) * 2007-08-22 2011-05-19 6570763 Canada Inc. Process for converting 9-dihydro-13acetylbaccatin iii paclitaxel and docetaxel
FR2926551A1 (fr) * 2008-01-17 2009-07-24 Aventis Pharma Sa Formes cristallines du dimethoxy docetaxel et leurs procedes de preparation
BR112012011457A2 (pt) 2009-10-29 2016-05-03 Aventis Pharma Sa uso antitumoral de cabazitaxel.
CN104650012A (zh) * 2013-11-22 2015-05-27 天士力控股集团有限公司 一种紫杉烷类化合物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5136060A (en) * 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
WO1993002067A1 (fr) * 1991-07-17 1993-02-04 Nippon Steel Corporation Compose antitumoral nsc-lsc1 et son procede de production
CA2100808A1 (en) * 1992-10-01 1994-04-02 Vittorio Farina Deoxy paclitaxels
SG73401A1 (en) * 1993-03-22 2000-06-20 Univ Florida State Taxanes having alkoxy alkenoxy or aryloxy substituted side-chain and pharmaceutical compositions containing the same
FR2711369B1 (fr) * 1993-10-20 1995-11-17 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions qui les contiennent.
PL187579B1 (pl) * 1994-07-26 2004-08-31 Indena Spa Nowe półsyntetyczne taksany, sposób wytwarzania półsyntetycznych taksanów, nowe związki pośrednie, nowe półsyntetyczne seko-taksany, sposób wytwarzania półsyntetycznych seko-taksanów i przeciwnowotworowe kompozycje farmaceutyczne
US6201140B1 (en) * 1994-07-28 2001-03-13 Bristol-Myers Squibb Company 7-0-ethers of taxane derivatives

Also Published As

Publication number Publication date
PT885208E (pt) 2001-11-30
SK121598A3 (en) 1999-01-11
AU2030297A (en) 1997-09-22
WO1997032869A1 (fr) 1997-09-12
KR19990087398A (ko) 1999-12-27
GR3036410T3 (en) 2001-11-30
EE9800264A (et) 1999-02-15
EP0885208A1 (fr) 1998-12-23
NO983472L (no) 1998-07-28
HUP9902425A2 (hu) 2001-04-28
US6160135A (en) 2000-12-12
IS4809A (is) 1998-07-24
AP1023A (en) 2001-11-16
EA199800795A1 (ru) 1999-02-25
CZ283498A3 (cs) 1999-01-13
ATE204266T1 (de) 2001-09-15
AP9801335A0 (en) 1998-09-30
CA2248195A1 (fr) 1997-09-12
EP0885208B1 (fr) 2001-08-16
DE69706146D1 (de) 2001-09-20
TR199801732T2 (xx) 1998-12-21
NO983472D0 (no) 1998-07-28
FR2745814A1 (fr) 1997-09-12
DK0885208T3 (da) 2001-10-15
BR9707887A (pt) 1999-09-21
ZA971746B (en) 1997-09-16
GEP20012517B (en) 2001-08-27
EA001516B1 (ru) 2001-04-23
BG63693B1 (bg) 2002-09-30
AU715228B2 (en) 2000-01-20
TW474928B (en) 2002-02-01
IL125998A0 (en) 1999-04-11
NZ331040A (en) 2000-02-28
CN1210525A (zh) 1999-03-10
IL125998A (en) 2002-02-10
PL328691A1 (en) 1999-02-15
ES2161446T3 (es) 2001-12-01
DE69706146T2 (de) 2002-05-02
EE03611B1 (et) 2002-02-15
JP2000506158A (ja) 2000-05-23
BG102753A (en) 1999-09-30
YU38398A (sh) 1999-07-28
FR2745814B1 (fr) 1998-04-03
HUP9902425A3 (en) 2001-08-28

Similar Documents

Publication Publication Date Title
CA2214321C (fr) Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
CA2238884C (fr) Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
EP0820448B1 (fr) Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
EP0885208B1 (fr) Taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
EP0821680B1 (fr) Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
EP0788492B1 (fr) Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2721023A1 (fr) Nouveaux Taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
EP0874838B1 (fr) Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
CA2190659C (fr) Taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2732341A1 (fr) Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
CA2214320C (fr) Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2732340A1 (fr) Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
WO1995033739A1 (fr) Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
WO1994012485A1 (fr) Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent