OA10242A - Sels de céphème cristallins d'addition avec des acides procédés pour leur préparation médicaments les contenant et leur utilisation - Google Patents

Sels de céphème cristallins d'addition avec des acides procédés pour leur préparation médicaments les contenant et leur utilisation Download PDF

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Publication number
OA10242A
OA10242A OA60734A OA60734A OA10242A OA 10242 A OA10242 A OA 10242A OA 60734 A OA60734 A OA 60734A OA 60734 A OA60734 A OA 60734A OA 10242 A OA10242 A OA 10242A
Authority
OA
OAPI
Prior art keywords
acides
acide
formule
que
acid
Prior art date
Application number
OA60734A
Other languages
English (en)
French (fr)
Inventor
Rudolf Dr Lattrell
Walter Dr Duerckheimer
Peter Dr Schmid
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of OA10242A publication Critical patent/OA10242A/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/48—Methylene radicals, substituted by hetero rings
    • C07D501/56—Methylene radicals, substituted by hetero rings with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
OA60734A 1994-11-10 1995-11-10 Sels de céphème cristallins d'addition avec des acides procédés pour leur préparation médicaments les contenant et leur utilisation OA10242A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4440141A DE4440141A1 (de) 1994-11-10 1994-11-10 Neue kristalline Cephem-Säureadditionssalze und Verfahren zu ihrer Herstellung

Publications (1)

Publication Number Publication Date
OA10242A true OA10242A (fr) 1997-09-19

Family

ID=6532953

Family Applications (1)

Application Number Title Priority Date Filing Date
OA60734A OA10242A (fr) 1994-11-10 1995-11-10 Sels de céphème cristallins d'addition avec des acides procédés pour leur préparation médicaments les contenant et leur utilisation

Country Status (28)

Country Link
US (1) US5747484A (no)
EP (1) EP0711774B1 (no)
JP (1) JP3920939B2 (no)
KR (1) KR100449191B1 (no)
CN (1) CN1066452C (no)
AR (1) AR002246A1 (no)
AT (1) ATE213248T1 (no)
AU (1) AU707730B2 (no)
BR (1) BR9505132A (no)
CA (1) CA2162530C (no)
CZ (1) CZ290936B6 (no)
DE (2) DE4440141A1 (no)
DK (1) DK0711774T3 (no)
ES (1) ES2172549T3 (no)
FI (1) FI120263B (no)
HU (1) HU219475B (no)
IL (1) IL115914A (no)
MA (1) MA23709A1 (no)
NO (1) NO311891B1 (no)
NZ (1) NZ280424A (no)
OA (1) OA10242A (no)
PL (1) PL182806B1 (no)
PT (1) PT711774E (no)
RU (1) RU2161619C2 (no)
SK (1) SK282545B6 (no)
TR (1) TR199501392A2 (no)
TW (1) TW422847B (no)
ZA (1) ZA959510B (no)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0980350A4 (en) * 1997-04-29 2003-01-02 Univ New Mexico ASYMMETRICAL SYNTHESIS OF BENZOXAZINOES ON NEW INTERMEDIATE PRODUCTS
PL208585B1 (pl) * 2002-10-25 2011-05-31 Intervet Int Bv Kompozycja farmaceutyczna o przedłużonym uwalnianiu zawierająca cefquinom, sposób jej wytwarzania i zastosowanie cefquinomu
JP5322649B2 (ja) * 2005-10-29 2013-10-23 インターベツト・インターナシヨナル・ベー・ベー セフキノム組成物およびその使用方法
TWI400243B (zh) * 2009-07-20 2013-07-01 Intervet Int Bv 製造西喹諾（ｃｅｆｑｕｉｎｏｍｅ）粒子的方法
EP3616695B1 (en) 2011-09-09 2024-10-23 Merck Sharp & Dohme LLC Ceftolozane/tazobactam for treating intrapulmonary infections
WO2013049294A1 (en) * 2011-09-29 2013-04-04 Alere San Diego, Inc. 2-hydroxyhippuric acid analogs, and methods for their synthesis and use
US8809314B1 (en) 2012-09-07 2014-08-19 Cubist Pharmacueticals, Inc. Cephalosporin compound
US8476425B1 (en) 2012-09-27 2013-07-02 Cubist Pharmaceuticals, Inc. Tazobactam arginine compositions
AU2014227660B2 (en) 2013-03-15 2014-11-06 Merck Sharp & Dohme Llc Ceftolozane antibiotic compositions
US20140274997A1 (en) 2013-03-15 2014-09-18 Cubist Pharmaceuticals, Inc. Cephalosporin pharmaceutical compositions
US9872906B2 (en) 2013-03-15 2018-01-23 Merck Sharp & Dohme Corp. Ceftolozane antibiotic compositions
US10376496B2 (en) 2013-09-09 2019-08-13 Merck, Sharp & Dohme Corp. Treating infections with ceftolozane/tazobactam in subjects having impaired renal function
US8906898B1 (en) 2013-09-27 2014-12-09 Calixa Therapeutics, Inc. Solid forms of ceftolozane

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3118732A1 (de) * 1981-05-12 1982-12-02 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
DE3248281A1 (de) * 1982-12-28 1984-06-28 Hoechst Ag, 6230 Frankfurt Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE3316797A1 (de) * 1983-05-07 1984-11-08 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von cephemverbindungen
DE3706020A1 (de) * 1987-02-25 1988-09-08 Hoechst Ag Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
FI955382A0 (fi) 1995-11-08
ES2172549T3 (es) 2002-10-01
FI120263B (fi) 2009-08-31
SK139795A3 (en) 1996-06-05
HU219475B (hu) 2001-04-28
CZ293395A3 (en) 1996-05-15
US5747484A (en) 1998-05-05
NZ280424A (en) 1997-06-24
AU3772895A (en) 1996-05-16
JP3920939B2 (ja) 2007-05-30
DK0711774T3 (da) 2002-04-22
EP0711774A1 (de) 1996-05-15
PL182806B1 (pl) 2002-03-29
SK282545B6 (sk) 2002-10-08
HU9503213D0 (en) 1996-01-29
JPH08208662A (ja) 1996-08-13
NO311891B1 (no) 2002-02-11
IL115914A (en) 2002-08-14
FI955382A (fi) 1996-05-11
AR002246A1 (es) 1998-03-11
HUT74163A (en) 1996-11-28
CN1066452C (zh) 2001-05-30
CA2162530A1 (en) 1996-05-11
IL115914A0 (en) 1996-01-31
ZA959510B (en) 1996-05-28
CN1129220A (zh) 1996-08-21
RU2161619C2 (ru) 2001-01-10
DE59510048D1 (de) 2002-03-21
NO954511D0 (no) 1995-11-09
AU707730B2 (en) 1999-07-15
DE4440141A1 (de) 1996-05-15
EP0711774B1 (de) 2002-02-13
PL311326A1 (en) 1996-05-13
ATE213248T1 (de) 2002-02-15
CA2162530C (en) 2007-07-31
PT711774E (pt) 2002-07-31
KR100449191B1 (ko) 2006-01-12
MA23709A1 (fr) 1996-07-01
CZ290936B6 (cs) 2002-11-13
TW422847B (en) 2001-02-21
KR960017670A (ko) 1996-06-17
BR9505132A (pt) 1997-09-09
NO954511L (no) 1996-05-13
TR199501392A2 (tr) 1996-07-21

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