OA10165A - Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease - Google Patents

Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease Download PDF

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Publication number
OA10165A
OA10165A OA60674A OA60674A OA10165A OA 10165 A OA10165 A OA 10165A OA 60674 A OA60674 A OA 60674A OA 60674 A OA60674 A OA 60674A OA 10165 A OA10165 A OA 10165A
Authority
OA
OAPI
Prior art keywords
salen
metal complex
antioxidant
alkyls
group
Prior art date
Application number
OA60674A
Other languages
English (en)
Inventor
Bernard Malfroy-Camine
Michel Baudry
Original Assignee
Eukarion Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eukarion Inc filed Critical Eukarion Inc
Publication of OA10165A publication Critical patent/OA10165A/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/06Free radical scavengers or antioxidants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005Compounds without a metal-carbon linkage

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Neurosurgery (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Anti-Oxidant Or Stabilizer Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Fats And Perfumes (AREA)
OA60674A 1992-12-07 1995-06-06 Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease OA10165A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/987,474 US5403834A (en) 1992-12-07 1992-12-07 Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease

Publications (1)

Publication Number Publication Date
OA10165A true OA10165A (en) 1996-12-18

Family

ID=25533292

Family Applications (1)

Application Number Title Priority Date Filing Date
OA60674A OA10165A (en) 1992-12-07 1995-06-06 Synthetic catalytic free radical scavengers useful as antioxidants for prevention and therapy of disease

Country Status (20)

Country Link
US (2) US5403834A (sk)
EP (2) EP0746321B1 (sk)
JP (1) JP3502099B2 (sk)
KR (1) KR20040004386A (sk)
AT (1) ATE290867T1 (sk)
AU (1) AU697399B2 (sk)
CA (1) CA2150937C (sk)
CZ (1) CZ296288B6 (sk)
DE (1) DE69333775T2 (sk)
GB (2) GB2277873B (sk)
HU (1) HU225109B1 (sk)
LV (1) LV10924B (sk)
NO (1) NO319454B1 (sk)
NZ (1) NZ259200A (sk)
OA (1) OA10165A (sk)
PL (1) PL175446B1 (sk)
RU (1) RU2157213C2 (sk)
SK (1) SK74595A3 (sk)
UA (1) UA27949C2 (sk)
WO (1) WO1994013300A1 (sk)

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Also Published As

Publication number Publication date
JPH08504211A (ja) 1996-05-07
LV10924B (en) 1996-10-20
SK74595A3 (en) 1996-05-08
GB2277873B (en) 1997-05-14
GB9415050D0 (en) 1994-09-14
DE69333775T2 (de) 2006-04-06
NZ259200A (en) 1997-06-24
NO319454B1 (no) 2005-08-15
PL175446B1 (pl) 1998-12-31
EP0746321A1 (en) 1996-12-11
AU5741994A (en) 1994-07-04
NO952237D0 (no) 1995-06-06
JP3502099B2 (ja) 2004-03-02
LV10924A (lv) 1995-12-20
HUT72967A (en) 1996-06-28
US5827880A (en) 1998-10-27
GB2305107B (en) 1997-05-14
UA27949C2 (uk) 2000-10-16
US5403834A (en) 1995-04-04
HU225109B1 (en) 2006-06-28
WO1994013300A1 (en) 1994-06-23
ATE290867T1 (de) 2005-04-15
GB9621087D0 (en) 1996-11-27
CZ296288B6 (cs) 2006-02-15
GB2305107A (en) 1997-04-02
CA2150937A1 (en) 1994-06-23
EP0746321B1 (en) 2005-03-16
CZ144295A3 (en) 1996-10-16
KR20040004386A (ko) 2004-01-13
HU9501644D0 (en) 1995-08-28
PL309334A1 (en) 1995-10-02
EP0746321A4 (en) 2001-05-09
GB2277873A (en) 1994-11-16
AU697399B2 (en) 1998-10-08
EP1642583A2 (en) 2006-04-05
NO952237L (no) 1995-08-01
RU2157213C2 (ru) 2000-10-10
DE69333775D1 (de) 2005-04-21
CA2150937C (en) 2007-08-14

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