OA10161A - Amine derivatives - Google Patents

Amine derivatives Download PDF

Info

Publication number
OA10161A
OA10161A OA60669A OA60669A OA10161A OA 10161 A OA10161 A OA 10161A OA 60669 A OA60669 A OA 60669A OA 60669 A OA60669 A OA 60669A OA 10161 A OA10161 A OA 10161A
Authority
OA
OAPI
Prior art keywords
phenyl
formula
compounds
methyl
oxo
Prior art date
Application number
OA60669A
Other languages
English (en)
Inventor
Duncan Robert Armour
Philip Charles Box
Pritom Shah
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of OA10161A publication Critical patent/OA10161A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
OA60669A 1992-12-05 1995-05-30 Amine derivatives OA10161A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929225492A GB9225492D0 (en) 1992-12-05 1992-12-05 Amine derivatives

Publications (1)

Publication Number Publication Date
OA10161A true OA10161A (en) 1996-12-18

Family

ID=10726205

Family Applications (1)

Application Number Title Priority Date Filing Date
OA60669A OA10161A (en) 1992-12-05 1995-05-30 Amine derivatives

Country Status (29)

Country Link
US (1) US5569654A (ko)
EP (1) EP0672037B1 (ko)
JP (1) JPH08504200A (ko)
KR (1) KR950704270A (ko)
CN (1) CN1093085A (ko)
AT (1) ATE168102T1 (ko)
AU (1) AU688295B2 (ko)
BG (1) BG99696A (ko)
BR (1) BR9307580A (ko)
CA (1) CA2150461A1 (ko)
CZ (1) CZ138495A3 (ko)
DE (1) DE69319614D1 (ko)
EC (1) ECSP941085A (ko)
FI (1) FI952709A (ko)
GB (1) GB9225492D0 (ko)
HU (1) HUT71339A (ko)
IL (1) IL107869A (ko)
MX (1) MX9307654A (ko)
NO (1) NO952208L (ko)
NZ (1) NZ258874A (ko)
OA (1) OA10161A (ko)
PE (1) PE54294A1 (ko)
PL (1) PL309281A1 (ko)
RO (1) RO114446B1 (ko)
RU (1) RU95114528A (ko)
SK (1) SK74195A3 (ko)
TW (1) TW237450B (ko)
WO (1) WO1994013648A1 (ko)
ZA (1) ZA939068B (ko)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9314981D0 (en) * 1993-07-20 1993-09-01 Glaxo Spa Chemical compounds
US5428157A (en) * 1993-11-22 1995-06-27 Merck & Co., Inc. 3-acylaminobenzodiazepines
AU2446295A (en) * 1994-04-15 1995-11-10 Glaxo Inc. A method of inducing cholecystokinin agonist activity using 1,4-benzodiazepine compounds
US5807876A (en) * 1996-04-23 1998-09-15 Vertex Pharmaceuticals Incorporated Inhibitors of IMPDH enzyme
AUPO284396A0 (en) * 1996-10-08 1996-10-31 Fujisawa Pharmaceutical Co., Ltd. Benzodiazepine derivatives
US6369080B2 (en) 1996-10-11 2002-04-09 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6262047B1 (en) 1996-10-11 2001-07-17 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6194435B1 (en) 1996-10-11 2001-02-27 Cor Therapeutics, Inc. Lactams as selective factor Xa inhibitors
US6063794A (en) 1996-10-11 2000-05-16 Cor Therapeutics Inc. Selective factor Xa inhibitors
EP0977772A1 (en) 1997-04-14 2000-02-09 Cor Therapeutics, Inc. SELECTIVE FACTOR Xa INHIBITORS
US6211183B1 (en) 1997-04-14 2001-04-03 Cor Therapeutics, Inc. Selective factor Xa inhibitors
JP2002514214A (ja) 1997-04-14 2002-05-14 シーオーアール セラピューティクス インコーポレイテッド 選択的Xa因子阻害剤
US6218382B1 (en) 1997-08-11 2001-04-17 Cor Therapeutics, Inc Selective factor Xa inhibitors
US6333321B1 (en) * 1997-08-11 2001-12-25 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6228854B1 (en) 1997-08-11 2001-05-08 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6100254A (en) * 1997-10-10 2000-08-08 Board Of Regents, The University Of Texas System Inhibitors of protein tyrosine kinases
US20080058424A1 (en) * 2002-05-23 2008-03-06 Cephalon, Inc. Novel pharmaceutical formulations of modafinil
ES2281527T3 (es) * 2001-05-25 2007-10-01 Cephalon, Inc. Formulaciones farmaceuticas solidas que comprenden modafinilo.
US7229644B2 (en) * 2002-05-23 2007-06-12 Cephalon, Inc. Pharmaceutical formulations of modafinil
US20040116532A1 (en) * 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
CA2589271A1 (en) * 2004-12-07 2006-06-15 Locus Pharmaceuticals, Inc. Urea inhibitors of map kinases
EP1824843A2 (en) * 2004-12-07 2007-08-29 Locus Pharmaceuticals, Inc. Inhibitors of protein kinases
CA2635888A1 (en) * 2006-01-04 2007-07-19 Locus Pharmaceuticals, Inc. Inhibitors of protein kinases
GB201414116D0 (en) * 2014-08-08 2014-09-24 Trio Medicines Ltd Benzodiazepine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2032226A1 (en) * 1989-12-18 1991-06-19 Mark G. Bock Benzodiazepine analogs
CA2068355A1 (en) * 1991-05-14 1992-11-15 Mark S. Chambers Benzodiazephine derivatives, compositions containing them and their use in therapy
GB9201180D0 (en) * 1992-01-21 1992-03-11 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
NO952208L (no) 1995-08-02
CN1093085A (zh) 1994-10-05
FI952709A (fi) 1995-08-01
PE54294A1 (es) 1995-01-06
WO1994013648A1 (en) 1994-06-23
DE69319614D1 (de) 1998-08-13
ECSP941085A (es) 1994-12-15
US5569654A (en) 1996-10-29
NZ258874A (en) 1996-09-25
ZA939068B (en) 1994-08-09
IL107869A (en) 1998-10-30
EP0672037A1 (en) 1995-09-20
RO114446B1 (ro) 1999-04-30
MX9307654A (es) 1994-06-30
AU688295B2 (en) 1998-03-12
ATE168102T1 (de) 1998-07-15
TW237450B (ko) 1995-01-01
IL107869A0 (en) 1994-04-12
SK74195A3 (en) 1995-11-08
HUT71339A (en) 1995-11-28
RU95114528A (ru) 1997-06-10
JPH08504200A (ja) 1996-05-07
CZ138495A3 (en) 1995-12-13
FI952709A0 (fi) 1995-06-02
GB9225492D0 (en) 1993-01-27
KR950704270A (ko) 1995-11-17
NO952208D0 (no) 1995-06-02
BG99696A (bg) 1996-01-31
PL309281A1 (en) 1995-10-02
BR9307580A (pt) 1999-06-29
CA2150461A1 (en) 1994-06-23
AU5694894A (en) 1994-07-04
HU9501622D0 (en) 1995-08-28
EP0672037B1 (en) 1998-07-08

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