BR9307580A - Compostos processo para a preparação dos mesmos composições farmacêuticas uso de um composto e processo de tratamento de um mamífero que inclui o ser humano - Google Patents

Compostos processo para a preparação dos mesmos composições farmacêuticas uso de um composto e processo de tratamento de um mamífero que inclui o ser humano

Info

Publication number
BR9307580A
BR9307580A BR9307580A BR9307580A BR9307580A BR 9307580 A BR9307580 A BR 9307580A BR 9307580 A BR9307580 A BR 9307580A BR 9307580 A BR9307580 A BR 9307580A BR 9307580 A BR9307580 A BR 9307580A
Authority
BR
Brazil
Prior art keywords
4alkyl
pct
optionally substituted
halogen
phenyl
Prior art date
Application number
BR9307580A
Other languages
English (en)
Inventor
Duncan Robert Armour
Philip Charles Box
Pritom Shah
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of BR9307580A publication Critical patent/BR9307580A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BR9307580A 1992-12-05 1993-12-02 Compostos processo para a preparação dos mesmos composições farmacêuticas uso de um composto e processo de tratamento de um mamífero que inclui o ser humano BR9307580A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929225492A GB9225492D0 (en) 1992-12-05 1992-12-05 Amine derivatives
PCT/EP1993/003381 WO1994013648A1 (en) 1992-12-05 1993-12-02 1,4-benzodiazepine derivatives and their use as cck-modulators

Publications (1)

Publication Number Publication Date
BR9307580A true BR9307580A (pt) 1999-06-29

Family

ID=10726205

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9307580A BR9307580A (pt) 1992-12-05 1993-12-02 Compostos processo para a preparação dos mesmos composições farmacêuticas uso de um composto e processo de tratamento de um mamífero que inclui o ser humano

Country Status (29)

Country Link
US (1) US5569654A (pt)
EP (1) EP0672037B1 (pt)
JP (1) JPH08504200A (pt)
KR (1) KR950704270A (pt)
CN (1) CN1093085A (pt)
AT (1) ATE168102T1 (pt)
AU (1) AU688295B2 (pt)
BG (1) BG99696A (pt)
BR (1) BR9307580A (pt)
CA (1) CA2150461A1 (pt)
CZ (1) CZ138495A3 (pt)
DE (1) DE69319614D1 (pt)
EC (1) ECSP941085A (pt)
FI (1) FI952709A (pt)
GB (1) GB9225492D0 (pt)
HU (1) HUT71339A (pt)
IL (1) IL107869A (pt)
MX (1) MX9307654A (pt)
NO (1) NO952208L (pt)
NZ (1) NZ258874A (pt)
OA (1) OA10161A (pt)
PE (1) PE54294A1 (pt)
PL (1) PL309281A1 (pt)
RO (1) RO114446B1 (pt)
RU (1) RU95114528A (pt)
SK (1) SK74195A3 (pt)
TW (1) TW237450B (pt)
WO (1) WO1994013648A1 (pt)
ZA (1) ZA939068B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9314981D0 (en) * 1993-07-20 1993-09-01 Glaxo Spa Chemical compounds
US5428157A (en) * 1993-11-22 1995-06-27 Merck & Co., Inc. 3-acylaminobenzodiazepines
AU2446295A (en) * 1994-04-15 1995-11-10 Glaxo Inc. A method of inducing cholecystokinin agonist activity using 1,4-benzodiazepine compounds
US5807876A (en) * 1996-04-23 1998-09-15 Vertex Pharmaceuticals Incorporated Inhibitors of IMPDH enzyme
AUPO284396A0 (en) * 1996-10-08 1996-10-31 Fujisawa Pharmaceutical Co., Ltd. Benzodiazepine derivatives
US6194435B1 (en) 1996-10-11 2001-02-27 Cor Therapeutics, Inc. Lactams as selective factor Xa inhibitors
US6063794A (en) 1996-10-11 2000-05-16 Cor Therapeutics Inc. Selective factor Xa inhibitors
US6262047B1 (en) 1996-10-11 2001-07-17 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6369080B2 (en) 1996-10-11 2002-04-09 Cor Therapeutics, Inc. Selective factor Xa inhibitors
EP0975625A1 (en) 1997-04-14 2000-02-02 Cor Therapeutics, Inc. SELECTIVE FACTOR Xa INHIBITORS
CA2285659A1 (en) 1997-04-14 1998-10-22 Cor Therapeutics, Inc. Selective factor xa inhibitors
WO1998046626A1 (en) 1997-04-14 1998-10-22 Cor Therapeutics, Inc. SELECTIVE FACTOR Xa INHIBITORS
US6333321B1 (en) * 1997-08-11 2001-12-25 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6218382B1 (en) 1997-08-11 2001-04-17 Cor Therapeutics, Inc Selective factor Xa inhibitors
US6228854B1 (en) 1997-08-11 2001-05-08 Cor Therapeutics, Inc. Selective factor Xa inhibitors
US6100254A (en) * 1997-10-10 2000-08-08 Board Of Regents, The University Of Texas System Inhibitors of protein tyrosine kinases
DE60219005T2 (de) * 2001-05-25 2007-12-13 Cephalon, Inc. Modafinil umfassende feste pharmazeutische Formulierungen
US20080058424A1 (en) * 2002-05-23 2008-03-06 Cephalon, Inc. Novel pharmaceutical formulations of modafinil
US7229644B2 (en) * 2002-05-23 2007-06-12 Cephalon, Inc. Pharmaceutical formulations of modafinil
US20040116532A1 (en) 2002-09-13 2004-06-17 Craig Heacock Pharmaceutical formulations of modafinil
JP2008523071A (ja) * 2004-12-07 2008-07-03 ルーカス ファーマシューティカルズ, インコーポレイテッド Mapキナーゼの尿素インヒビター
EP1824843A2 (en) * 2004-12-07 2007-08-29 Locus Pharmaceuticals, Inc. Inhibitors of protein kinases
CA2635888A1 (en) * 2006-01-04 2007-07-19 Locus Pharmaceuticals, Inc. Inhibitors of protein kinases
GB201414116D0 (en) * 2014-08-08 2014-09-24 Trio Medicines Ltd Benzodiazepine derivatives

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2032226A1 (en) * 1989-12-18 1991-06-19 Mark G. Bock Benzodiazepine analogs
CA2068355A1 (en) * 1991-05-14 1992-11-15 Mark S. Chambers Benzodiazephine derivatives, compositions containing them and their use in therapy
GB9201180D0 (en) * 1992-01-21 1992-03-11 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
AU5694894A (en) 1994-07-04
NO952208L (no) 1995-08-02
US5569654A (en) 1996-10-29
IL107869A0 (en) 1994-04-12
SK74195A3 (en) 1995-11-08
IL107869A (en) 1998-10-30
RU95114528A (ru) 1997-06-10
TW237450B (pt) 1995-01-01
WO1994013648A1 (en) 1994-06-23
MX9307654A (es) 1994-06-30
HU9501622D0 (en) 1995-08-28
FI952709A0 (fi) 1995-06-02
EP0672037B1 (en) 1998-07-08
RO114446B1 (ro) 1999-04-30
BG99696A (bg) 1996-01-31
FI952709A (fi) 1995-08-01
GB9225492D0 (en) 1993-01-27
KR950704270A (ko) 1995-11-17
CZ138495A3 (en) 1995-12-13
HUT71339A (en) 1995-11-28
JPH08504200A (ja) 1996-05-07
PE54294A1 (es) 1995-01-06
ECSP941085A (es) 1994-12-15
NZ258874A (en) 1996-09-25
OA10161A (en) 1996-12-18
ATE168102T1 (de) 1998-07-15
DE69319614D1 (de) 1998-08-13
PL309281A1 (en) 1995-10-02
ZA939068B (en) 1994-08-09
EP0672037A1 (en) 1995-09-20
CA2150461A1 (en) 1994-06-23
NO952208D0 (no) 1995-06-02
AU688295B2 (en) 1998-03-12
CN1093085A (zh) 1994-10-05

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
FC Decision: refusal