OA09982A - Derives heterocycliques leur procede de production et composition pharmaceutique les contenant - Google Patents
Derives heterocycliques leur procede de production et composition pharmaceutique les contenantInfo
- Publication number
- OA09982A OA09982A OA60222A OA60222A OA09982A OA 09982 A OA09982 A OA 09982A OA 60222 A OA60222 A OA 60222A OA 60222 A OA60222 A OA 60222A OA 09982 A OA09982 A OA 09982A
- Authority
- OA
- OAPI
- Prior art keywords
- pharmaceutical composition
- composition containing
- production process
- heterocyclic derivatives
- compounds
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Ophthalmology & Optometry (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919111759A GB9111759D0 (en) | 1991-05-31 | 1991-05-31 | Heterocyclic compounds |
GB919116309A GB9116309D0 (en) | 1991-07-29 | 1991-07-29 | Bicyclic derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
OA09982A true OA09982A (fr) | 1996-03-29 |
Family
ID=26298984
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
OA60222A OA09982A (fr) | 1991-05-31 | 1992-05-29 | Derives heterocycliques leur procede de production et composition pharmaceutique les contenant |
Country Status (21)
Country | Link |
---|---|
US (2) | US5217976A (fr) |
EP (1) | EP0516392B1 (fr) |
JP (1) | JPH05163271A (fr) |
KR (1) | KR920021545A (fr) |
CN (1) | CN1073174A (fr) |
AT (1) | ATE204873T1 (fr) |
AU (1) | AU1625192A (fr) |
CA (1) | CA2068946A1 (fr) |
CS (1) | CS161892A3 (fr) |
DE (1) | DE69232022D1 (fr) |
FI (1) | FI922481A (fr) |
GB (1) | GB2256196B (fr) |
HU (1) | HUT61303A (fr) |
IE (1) | IE921506A1 (fr) |
IL (1) | IL101860A0 (fr) |
NO (1) | NO922147L (fr) |
OA (1) | OA09982A (fr) |
PL (1) | PL294736A1 (fr) |
SI (1) | SI9200095A (fr) |
TW (1) | TW213914B (fr) |
YU (1) | YU56192A (fr) |
Families Citing this family (71)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH07505646A (ja) * | 1992-04-13 | 1995-06-22 | ゼネカ・リミテッド | 神経伝達速度の減損を伴う障害,特に糖尿病性ニューロパシーに対するアンギオテンシンiiアンタゴニスト |
GB9208116D0 (en) | 1992-04-13 | 1992-05-27 | Ici Plc | Therapeutic agents |
GB9211270D0 (en) * | 1992-05-28 | 1992-07-15 | Ici Plc | Nitrogen compounds |
EP0618207B1 (fr) * | 1993-03-24 | 1999-01-07 | American Home Products Corporation | Pyridopyrimidines substituées comme antihypertensives |
US5466692A (en) * | 1993-03-24 | 1995-11-14 | American Home Products Corporation | Substituted pyridopyrimidines and antihypertensives |
US5468867A (en) * | 1994-05-27 | 1995-11-21 | Syntex (U.S.A.) Inc. | Process for preparing1-butyl-2-[2'-(2H-tetrazol-5-yl)biphenyl-4-ylmethyl1-1H-indole-3-carboxylic acid |
US5412102A (en) * | 1994-05-27 | 1995-05-02 | Syntex (U.S.A.) Inc. | Processes for preparing 1-butyl-2-[2'-(2H-tetrazol-5-yl) biphenyl-4-ylmethyl]-1H-indole-3-carboxylic acid |
US5801183A (en) * | 1995-01-27 | 1998-09-01 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon | Aza and aza (N-oxy) analogs of glycine/NMDA receptor antagonists |
ZA985870B (en) * | 1997-07-15 | 1999-01-27 | Dainippon Pharmaceutical Co | 5-substituted-3-oxadiazolyl-1, 6-naphthyridin-2(1H)-one derivatives |
SE9903028D0 (sv) | 1999-08-27 | 1999-08-27 | Astra Ab | New use |
US6919351B2 (en) * | 2000-10-12 | 2005-07-19 | Merck & Co., Inc. | Aza-and polyaza-naphthalenyl-carboxamides useful as HIV integrase inhibitors |
AU1152702A (en) | 2000-10-12 | 2002-04-22 | Merck & Co Inc | Aza- and polyaza-naphthalenyl carboxamides useful as hiv integrase inhibitors |
ES2274913T3 (es) * | 2000-10-12 | 2007-06-01 | MERCK & CO., INC. | Aza y poliaza-naftalenil carboxamidas utiles como inhibidores de vih integrada. |
AR036256A1 (es) * | 2001-08-17 | 2004-08-25 | Merck & Co Inc | Sal sodica de un inhibidor de integrasa del vih, procesos para su preparacion, composiciones farmaceuticas que lo contienen y su uso para la manufactura de un medicamento |
BR0212864A (pt) | 2001-09-26 | 2004-08-17 | Bayer Pharmaceuticals Corp | Derivados de 1,6-naftiridina como antidiabéticos |
DE60315796T2 (de) * | 2002-01-17 | 2008-06-05 | Merck & Co., Inc. | Hydroxynaphthyridinoncarbonsäureamide, die sich als inhibitoren der hiv-integrase eignen |
US7323460B2 (en) * | 2002-03-15 | 2008-01-29 | Merck & Co., Inc. | N-(substituted benzyl)-8-hydroxy-1,6-naphthyridine-7-carboxamides useful as HIV integrase inhibitors |
NZ536504A (en) * | 2002-05-24 | 2008-04-30 | Millennium Pharm Inc | CCR9 inhibitors and methods of use thereof |
WO2004011429A1 (fr) * | 2002-07-26 | 2004-02-05 | Nihon Nohyaku Co., Ltd. | Nouveaux derives d'haloalkylsulfonanilide, herbicides et utilisation de ceux-ci |
JP2004107323A (ja) * | 2002-07-26 | 2004-04-08 | Nippon Nohyaku Co Ltd | 新規なハロアルキルスルホンアニリド誘導体及び除草剤並びにその使用方法 |
CA2498111A1 (fr) * | 2002-09-11 | 2004-03-25 | Merck & Co., Inc. | Composes de dihydroxypyridopyrazine-1,6-diones utiles en tant qu'inhibiteurs de l'integrase du vih |
US7399763B2 (en) * | 2002-09-11 | 2008-07-15 | Merck & Co., Inc. | 8-hydroxy-1-oxo-tetrahydropyrrolopyrazine compounds useful as HIV integrase inhibitors |
WO2005023183A2 (fr) * | 2003-08-28 | 2005-03-17 | Nitromed, Inc. | Composes diuretiques nitroses et nitrosyles, compositions et procedes d'utilisation correspondants |
CN1870896A (zh) * | 2003-10-20 | 2006-11-29 | 默克公司 | 用作hiv整合酶抑制剂的羟基吡啶并吡咯并吡嗪二酮化合物 |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
CA3089569C (fr) | 2007-06-04 | 2023-12-05 | Synergy Pharmaceuticals Inc. | Agonistes de guanylase cyclase utiles pour le traitement de troubles gastro-intestinaux, d'inflammation, de cancer et d'autres troubles |
EP2321341B1 (fr) | 2008-07-16 | 2017-02-22 | Synergy Pharmaceuticals Inc. | Agonistes de guanylate cyclase utiles pour le traitement de troubles gastro-intestinaux, inflammatoires, cancéreux et autres |
EP2387575B1 (fr) | 2009-01-15 | 2013-09-04 | Anvyl, LLC | Modulateurs allostériques des récepteurs nicotiniques de l'acétylcholine de type alpha7, leurs dérivés et leurs utilisations |
SI2448938T1 (sl) | 2009-06-29 | 2014-08-29 | Incyte Corporation Experimental Station | Pirimidinoni kot zaviralci pi3k |
WO2011031745A1 (fr) | 2009-09-09 | 2011-03-17 | Achaogen, Inc. | Analogues de fluoroquinolone antibactériens |
AR079529A1 (es) * | 2009-12-18 | 2012-02-01 | Incyte Corp | Derivados arilo y heteroarilo sustituidos y fundidos como inhibidores de la pi3k |
WO2011075643A1 (fr) | 2009-12-18 | 2011-06-23 | Incyte Corporation | Dérivés condensés d'hétéroaryles substitués à titre d'inhibiteurs de pi3k |
US9193721B2 (en) | 2010-04-14 | 2015-11-24 | Incyte Holdings Corporation | Fused derivatives as PI3Kδ inhibitors |
RU2438672C1 (ru) * | 2010-04-30 | 2012-01-10 | Общество с ограниченной ответственностью "Клевер Фарм" | Агент, проявляющий свойства активатора когнитивных функций (варианты) |
WO2011163195A1 (fr) | 2010-06-21 | 2011-12-29 | Incyte Corporation | Dérivés condensés de pyrrole en tant qu'inhibiteurs de pi3k |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
JP5961187B2 (ja) | 2010-12-20 | 2016-08-02 | インサイト・ホールディングス・コーポレイションIncyte Holdings Corporation | Pi3k阻害剤としてのn−(1−(置換フェニル)エチル)−9h−プリン−6−アミン |
US9108984B2 (en) | 2011-03-14 | 2015-08-18 | Incyte Corporation | Substituted diamino-pyrimidine and diamino-pyridine derivatives as PI3K inhibitors |
WO2012135009A1 (fr) | 2011-03-25 | 2012-10-04 | Incyte Corporation | Dérivés de pyrimidine-4,6-diamine en tant qu'inhibiteurs de pi3k |
CA2846652C (fr) | 2011-09-02 | 2019-11-05 | Incyte Corporation | Heterocyclylamines en tant qu'inhibiteurs de pi3k |
KR20140091022A (ko) | 2011-10-31 | 2014-07-18 | 제논 파마슈티칼스 인크. | 벤젠술폰아미드 화합물 및 치료제로서의 그의 용도 |
CN104093716B (zh) | 2011-10-31 | 2017-06-23 | 克赛农制药股份有限公司 | 联芳醚磺酰胺化合物及其作为治疗剂的用途 |
AR090548A1 (es) | 2012-04-02 | 2014-11-19 | Incyte Corp | Azaheterociclobencilaminas biciclicas como inhibidores de pi3k |
EA026393B1 (ru) * | 2012-05-22 | 2017-04-28 | Дженентек, Инк. | N-замещенные бензамиды и их применение в лечении боли |
CN104487427B (zh) * | 2012-06-25 | 2017-03-15 | 萨尼奥纳有限责任公司 | 四唑衍生物和它们作为钾通道调节剂的用途 |
WO2014008458A2 (fr) | 2012-07-06 | 2014-01-09 | Genentech, Inc. | Benzamides n-substitués et leurs procédés d'utilisation |
BR112015022488A2 (pt) | 2013-03-14 | 2017-07-18 | Genentech Inc | triazolopiridinas substituídas e métodos de uso das mesmas |
EP2970384A1 (fr) | 2013-03-15 | 2016-01-20 | Synergy Pharmaceuticals Inc. | Agonistes de la guanylate cyclase et leurs utilisations |
JP2016514670A (ja) | 2013-03-15 | 2016-05-23 | シナジー ファーマシューティカルズ インコーポレイテッド | 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト |
EP2970156B1 (fr) | 2013-03-15 | 2018-07-25 | Genentech, Inc. | Benzoxazoles substitués et leurs procédés d'utilisation |
RS65632B1 (sr) | 2013-06-05 | 2024-07-31 | Bausch Health Ireland Ltd | Ultra-prečišćeni agonisti guanilat-ciklaze c, postupak njihove pripreme i upotrebe |
CN104418853B (zh) * | 2013-08-28 | 2016-09-07 | 北大方正集团有限公司 | 取代的萘啶-2-酮化合物、制备方法、用途及药物组合物 |
EA201691085A1 (ru) | 2013-11-27 | 2017-02-28 | Дженентек, Инк. | Замещенные бензамиды и способы их применения |
US10065945B2 (en) | 2014-01-24 | 2018-09-04 | Merck Sharp & Dohme Corp. | Isoquinoline derivatives as MGAT2 inhibitors |
WO2015191677A1 (fr) | 2014-06-11 | 2015-12-17 | Incyte Corporation | Dérivés d'hétéroarylaminoalkylphényle bicycliques à titre d'inhibiteurs de pi3k |
CN106715418A (zh) | 2014-07-07 | 2017-05-24 | 基因泰克公司 | 治疗化合物及其使用方法 |
ES2905564T3 (es) | 2014-12-22 | 2022-04-11 | Us Health | Inhibidores mutantes de IDH1 útiles para tratar el cáncer |
ES2843522T3 (es) | 2015-02-27 | 2021-07-19 | Incyte Corp | Sales del inhibidor de PI3K y procesos para su preparación |
WO2016183060A1 (fr) | 2015-05-11 | 2016-11-17 | Incyte Corporation | Procédé de synthèse d'un inhibiteur de phospho-inositide 3-kinases |
WO2016183063A1 (fr) | 2015-05-11 | 2016-11-17 | Incyte Corporation | Formes cristallines d'un inhibiteur de pi3k |
CA2986045A1 (fr) | 2015-05-22 | 2016-12-01 | Genentech, Inc. | Benzamides substitues et leurs methodes d'utilisation |
CN108137477A (zh) | 2015-08-27 | 2018-06-08 | 基因泰克公司 | 治疗化合物及其使用方法 |
SG10202007787RA (en) | 2015-09-28 | 2020-09-29 | Genentech Inc | Therapeutic compounds and methods of use thereof |
MA43304A (fr) | 2015-11-25 | 2018-10-03 | Genentech Inc | Benzamides substitués utiles en tant que bloqueurs de canaux sodiques |
EP3854782A1 (fr) | 2016-03-30 | 2021-07-28 | Genentech, Inc. | Benzamides substitués et leurs procédés d'utilisation |
JOP20190086A1 (ar) | 2016-10-21 | 2019-04-18 | Novartis Ag | مشتقات نافثيريدينون جديدة واستخدامها في معالجة عدم انتظام ضربات القلب |
JP2020511511A (ja) | 2017-03-24 | 2020-04-16 | ジェネンテック, インコーポレイテッド | ナトリウムチャネル阻害剤としての4−ピペリジン−n−(ピリミジン−4−イル)クロマン−7−スルホンアミド誘導体 |
WO2019165290A1 (fr) | 2018-02-26 | 2019-08-29 | Genentech, Inc. | Composés de pyridine-sulfonamide et leur utilisation contre la douleur et les états associés |
CN111936494A (zh) | 2018-03-30 | 2020-11-13 | 豪夫迈·罗氏有限公司 | 作为钠通道抑制剂的取代的氢-吡啶并-吖嗪 |
CN111909170B (zh) * | 2020-09-11 | 2022-08-12 | 吉林奥来德光电材料股份有限公司 | 一种有机电致发光化合物、其制备方法以及包含该有机电致发光化合物的有机电致发光器件 |
EP4426434A1 (fr) | 2021-11-02 | 2024-09-11 | Flare Therapeutics, Inc. | Agonistes inverses de pparg et leurs utilisations |
Family Cites Families (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4920132A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
US4920130A (en) * | 1987-11-02 | 1990-04-24 | Rorer Pharamceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
US4920131A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
IL89029A (en) * | 1988-01-29 | 1993-01-31 | Lilly Co Eli | Fungicidal quinoline and cinnoline derivatives, compositions containing them, and fungicidal methods of using them |
GT198900008A (es) * | 1988-01-29 | 1990-07-17 | Derivados de quinolina, quinazolina y cinolina. | |
IE64514B1 (en) * | 1989-05-23 | 1995-08-09 | Zeneca Ltd | Azaindenes |
IL94390A (en) * | 1989-05-30 | 1996-03-31 | Merck & Co Inc | The 6-membered trans-nitrogen-containing heterocycles are compressed with imidazo and pharmaceutical preparations containing them |
CA2020073A1 (fr) * | 1989-07-03 | 1991-01-04 | Eric E. Allen | Quinazolinones substitues comme antagonistes de l'angiotensine ii |
EP0407342A3 (en) * | 1989-07-06 | 1991-07-10 | Ciba-Geigy Ag | Pyrimidine derivatives |
EP0412594B1 (fr) * | 1989-07-28 | 1996-01-03 | Merck & Co. Inc. | Triazolinones, triazolinethiones et triazolinimines substituées comme antagonistes d'angiotensine II |
BG92674A (bg) * | 1989-08-11 | 1993-12-24 | David Roberts | Метод за получаване на производни на хинолина |
EP0424317A3 (en) * | 1989-10-19 | 1991-09-25 | Ciba-Geigy Ag | Pyrimidines |
IE903911A1 (en) * | 1989-11-20 | 1991-05-22 | Ici Plc | Diazine derivatives |
EP0435827A3 (en) * | 1989-12-28 | 1991-11-13 | Ciba-Geigy Ag | Diaza compounds |
WO1991009598A1 (fr) * | 1990-01-05 | 1991-07-11 | Pfizer Inc. | Derives de l'azaoxindole |
CA2037630C (fr) * | 1990-03-07 | 2001-07-03 | Akira Morimoto | Composes heterocycliques renfermant de l'azote, methode de production et applications correspondantes |
PT97078B (pt) * | 1990-03-20 | 1997-07-31 | Sanofi Sa | Processo para a preparacao de derivados heterociclicos n-substituidos e de composicoes farmaceuticas que os contem |
EP0453210A3 (en) * | 1990-04-19 | 1993-01-13 | Imperial Chemical Industries Plc | Pyridine derivatives |
CA2051705A1 (fr) * | 1990-06-19 | 1991-12-20 | Kiyoaki Katano | Derives de la pyridine, antagonistes de l'angiotensine ii |
IL99246A0 (en) * | 1990-09-10 | 1992-07-15 | Abbott Lab | Angiotensin ii receptor antagonists and pharmaceutical compositions containing them |
IL100555A (en) * | 1991-02-07 | 2000-08-31 | Hoechst Marion Roussel Inc | N-substituted quinoline derivatives their preparation their use for the preparation of medicaments and the pharmaceutical compositions containing them |
IL100917A0 (en) * | 1991-02-16 | 1992-11-15 | Fisons Plc | Pyridinone and pyrimidinone derivatives,their preparation and pharmaceutical compositions containing them |
TW274551B (fr) * | 1991-04-16 | 1996-04-21 | Takeda Pharm Industry Co Ltd | |
US5149699A (en) * | 1991-10-24 | 1992-09-22 | American Home Products Corporation | Substituted pyridopyrimidines useful as antgiotensin II antagonists |
-
1992
- 1992-05-14 AU AU16251/92A patent/AU1625192A/en not_active Abandoned
- 1992-05-14 IL IL101860A patent/IL101860A0/xx unknown
- 1992-05-15 HU HU9201608A patent/HUT61303A/hu unknown
- 1992-05-19 CA CA002068946A patent/CA2068946A1/fr not_active Abandoned
- 1992-05-26 CS CS921618A patent/CS161892A3/cs unknown
- 1992-05-27 DE DE69232022T patent/DE69232022D1/de not_active Expired - Lifetime
- 1992-05-27 GB GB9211211A patent/GB2256196B/en not_active Revoked
- 1992-05-27 AT AT92304791T patent/ATE204873T1/de active
- 1992-05-27 EP EP92304791A patent/EP0516392B1/fr not_active Expired - Lifetime
- 1992-05-29 NO NO92922147A patent/NO922147L/no unknown
- 1992-05-29 FI FI922481A patent/FI922481A/fi not_active Application Discontinuation
- 1992-05-29 US US07/890,453 patent/US5217976A/en not_active Expired - Fee Related
- 1992-05-29 SI SI19929200095A patent/SI9200095A/sl unknown
- 1992-05-29 CN CN92104257A patent/CN1073174A/zh active Pending
- 1992-05-29 OA OA60222A patent/OA09982A/fr unknown
- 1992-05-29 PL PL29473692A patent/PL294736A1/xx unknown
- 1992-05-29 KR KR1019920009442A patent/KR920021545A/ko not_active Application Discontinuation
- 1992-05-29 YU YU56192A patent/YU56192A/sh unknown
- 1992-06-01 JP JP4140731A patent/JPH05163271A/ja active Pending
- 1992-06-12 TW TW081104601A patent/TW213914B/zh active
- 1992-07-01 IE IE150692A patent/IE921506A1/en not_active Application Discontinuation
-
1993
- 1993-04-02 US US08/042,321 patent/US5294620A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU1625192A (en) | 1992-12-03 |
FI922481A (fi) | 1992-12-01 |
TW213914B (fr) | 1993-10-01 |
EP0516392B1 (fr) | 2001-08-29 |
NO922147L (no) | 1992-12-01 |
US5294620A (en) | 1994-03-15 |
GB2256196A (en) | 1992-12-02 |
PL294736A1 (en) | 1993-05-31 |
CA2068946A1 (fr) | 1992-12-01 |
IE921506A1 (en) | 1992-12-02 |
FI922481A0 (fi) | 1992-05-29 |
DE69232022D1 (de) | 2001-10-04 |
JPH05163271A (ja) | 1993-06-29 |
CS161892A3 (en) | 1992-12-16 |
HU9201608D0 (en) | 1992-08-28 |
YU56192A (sh) | 1994-11-15 |
NO922147D0 (no) | 1992-05-29 |
KR920021545A (ko) | 1992-12-18 |
HUT61303A (en) | 1992-12-28 |
SI9200095A (en) | 1992-12-31 |
EP0516392A3 (en) | 1993-01-27 |
GB9211211D0 (en) | 1992-07-08 |
IL101860A0 (en) | 1992-12-30 |
EP0516392A2 (fr) | 1992-12-02 |
CN1073174A (zh) | 1993-06-16 |
GB2256196B (en) | 1995-05-10 |
US5217976A (en) | 1993-06-08 |
ATE204873T1 (de) | 2001-09-15 |
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