OA07586A - Acide 6,7-dihydro-5,8-diméthyl-9-floro-1-oxo-1H,5H-benzo (ij)quinolizine-2-carboxylique et ses dérivés et leur procédé de préparation. - Google Patents
Acide 6,7-dihydro-5,8-diméthyl-9-floro-1-oxo-1H,5H-benzo (ij)quinolizine-2-carboxylique et ses dérivés et leur procédé de préparation.Info
- Publication number
- OA07586A OA07586A OA58156A OA58156A OA07586A OA 07586 A OA07586 A OA 07586A OA 58156 A OA58156 A OA 58156A OA 58156 A OA58156 A OA 58156A OA 07586 A OA07586 A OA 07586A
- Authority
- OA
- OAPI
- Prior art keywords
- quinolizine
- benzo
- dihydro
- oxo
- dimethyl
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000002253 acid Substances 0.000 abstract 2
- -1 alkylaminoalkyl ester salts Chemical class 0.000 abstract 2
- 150000001263 acyl chlorides Chemical class 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 230000003389 potentiating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/441,245 US4472405A (en) | 1982-11-12 | 1982-11-12 | Antimicrobial 6,7-dihydro-5,8-dimethyl-9 fluoro-1-oxo-1H, 5H-benzo (ij) quinolizine-2-carboxylic acid and derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA07586A true OA07586A (fr) | 1985-03-31 |
Family
ID=23752110
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA58156A OA07586A (fr) | 1982-11-12 | 1983-11-10 | Acide 6,7-dihydro-5,8-diméthyl-9-floro-1-oxo-1H,5H-benzo (ij)quinolizine-2-carboxylique et ses dérivés et leur procédé de préparation. |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US4472405A (cs) |
| EP (1) | EP0109284B1 (cs) |
| JP (1) | JPH0826017B2 (cs) |
| KR (1) | KR890000864B1 (cs) |
| AT (1) | ATE39926T1 (cs) |
| AU (1) | AU568319B2 (cs) |
| CA (2) | CA1254568A (cs) |
| CS (1) | CS390391A3 (cs) |
| DE (1) | DE3378912D1 (cs) |
| EG (1) | EG16492A (cs) |
| ES (1) | ES527163A0 (cs) |
| FI (1) | FI73213C (cs) |
| GR (1) | GR79402B (cs) |
| IE (1) | IE56232B1 (cs) |
| IL (1) | IL70198A (cs) |
| IN (1) | IN161391B (cs) |
| MX (1) | MX7314E (cs) |
| NO (1) | NO160782C (cs) |
| NZ (1) | NZ206233A (cs) |
| OA (1) | OA07586A (cs) |
| PT (1) | PT77649B (cs) |
| ZA (1) | ZA838436B (cs) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3519926A1 (de) * | 1985-06-04 | 1986-12-04 | Bayer Ag | Indolinderivate, verfahren zu ihrer herstellung und diese indolinderivate enthaltende kosmetische lichtschutzmittel |
| US4898945A (en) * | 1986-01-22 | 1990-02-06 | Minnesota Mining And Manufacturing Company | Process for 6,7-dihydro-5,8-dimethyl-9-fluoro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acid |
| CA1302413C (en) * | 1986-01-22 | 1992-06-02 | Bruce E. Williams | Process for 6,7-dihydro-5,8-dimethyl-9-fluoro-1-oxo- 1h,5h-benzo[ij]quinolizine-2-carboxylic acid |
| GB9827865D0 (en) * | 1998-12-18 | 1999-02-10 | Woodcock Fiona | Medicament |
| DE10312346A1 (de) * | 2003-03-20 | 2004-09-30 | Bayer Healthcare Ag | Kontrolliertes Freisetzungssystem |
| DE10351448A1 (de) | 2003-11-04 | 2005-06-09 | Bayer Healthcare Ag | Geschmackstoffhaltige Arzneimittelformulierungen mit verbesserten pharmazeutischen Eigenschaften |
| DE102005055385A1 (de) * | 2004-12-09 | 2006-06-14 | Bayer Healthcare Ag | Arzneimittel zur hygienischen Applikation im Ohr |
| DE102006010643A1 (de) | 2006-03-08 | 2007-09-13 | Bayer Healthcare Aktiengesellschaft | Arzneimittel enthaltend Fluorchinolone |
| DE102006010642A1 (de) * | 2006-03-08 | 2007-09-27 | Bayer Healthcare Aktiengesellschaft | Arzneimittelformulierungen, enthaltend Fluorchinolone |
| DE102007026550A1 (de) | 2007-06-08 | 2008-12-11 | Bayer Healthcare Ag | Extrudate mit verbesserter Geschmacksmaskierung |
| DE102007055341A1 (de) | 2007-11-19 | 2009-05-20 | Bayer Animal Health Gmbh | Stabilisierung öliger Suspensionen enthaltend hydrophobe Kieselsäuren |
| ES2806256T3 (es) | 2010-10-12 | 2021-02-17 | Bayer Ip Gmbh | Productos masticables blandos no basados en almidón |
| UA118748C2 (uk) | 2012-12-19 | 2019-03-11 | Байєр Енімал Хелс Гмбх | Таблетки, що мають покращене сприйняття та хорошу стабільність при зберіганні |
| MD4291C1 (ro) * | 2013-12-27 | 2015-02-28 | Государственный Медицинский И Фармацевтический Университет "Nicolae Testemitanu" Республики Молдова | Preparat medicamentos pentru tratamentul otitelor |
| CN113853196B (zh) | 2019-05-24 | 2024-04-12 | 皮埃蒙特动物健康公司 | 长效可注射调配物和其用途 |
| WO2021046305A1 (en) * | 2019-09-06 | 2021-03-11 | Bayer Healthcare Llc | Palatable granular veterinary compositions |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA728444B (en) * | 1971-12-30 | 1973-10-31 | Riker Laboratories Inc | Substituted benzo(ij)quinolizine-2-carboxylic acids and derivatives thereof |
| BE793524A (fr) * | 1971-12-30 | 1973-06-29 | Riker Laboratories Inc | Acides benzoquinolizine-carboxyliques et leurs derives |
| JPS5630964A (en) * | 1979-08-22 | 1981-03-28 | Kyorin Pharmaceut Co Ltd | Novel substituted quinolinecarboxylic acid and its preparation |
| JPS5655388A (en) | 1979-10-11 | 1981-05-15 | Otsuka Pharmaceut Co Ltd | Benzo ij quinolidine-2-carboxylic acid derivative, and its preparation |
| US4301289A (en) * | 1980-02-19 | 1981-11-17 | Minnesota Mining And Manufacturing Company | Process for 6,7-dihydro-9-fluoro-5-methyl-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid |
| JPS59155381A (ja) * | 1983-02-22 | 1984-09-04 | Kyorin Pharmaceut Co Ltd | ベンゾキノリジンカルボン酸誘導体及びその製造法 |
-
1982
- 1982-11-12 US US06/441,245 patent/US4472405A/en not_active Expired - Lifetime
-
1983
- 1983-10-27 CA CA000439826A patent/CA1254568A/en not_active Expired
- 1983-11-09 NO NO834093A patent/NO160782C/no unknown
- 1983-11-10 OA OA58156A patent/OA07586A/xx unknown
- 1983-11-10 ES ES527163A patent/ES527163A0/es active Granted
- 1983-11-11 GR GR72947A patent/GR79402B/el unknown
- 1983-11-11 IN IN1382/CAL/83A patent/IN161391B/en unknown
- 1983-11-11 DE DE8383306908T patent/DE3378912D1/de not_active Expired
- 1983-11-11 NZ NZ206233A patent/NZ206233A/en unknown
- 1983-11-11 MX MX8310883U patent/MX7314E/es unknown
- 1983-11-11 IE IE2639/83A patent/IE56232B1/en not_active IP Right Cessation
- 1983-11-11 JP JP58212306A patent/JPH0826017B2/ja not_active Expired - Lifetime
- 1983-11-11 PT PT77649A patent/PT77649B/pt not_active IP Right Cessation
- 1983-11-11 AT AT83306908T patent/ATE39926T1/de not_active IP Right Cessation
- 1983-11-11 ZA ZA838436A patent/ZA838436B/xx unknown
- 1983-11-11 AU AU21181/83A patent/AU568319B2/en not_active Ceased
- 1983-11-11 IL IL70198A patent/IL70198A/xx not_active IP Right Cessation
- 1983-11-11 FI FI834147A patent/FI73213C/fi not_active IP Right Cessation
- 1983-11-11 EP EP83306908A patent/EP0109284B1/en not_active Expired
- 1983-11-12 KR KR1019830005376A patent/KR890000864B1/ko not_active Expired
- 1983-11-12 EG EG70383A patent/EG16492A/xx active
-
1988
- 1988-08-05 CA CA000574069A patent/CA1280755C/en not_active Expired - Fee Related
-
1991
- 1991-12-19 CS CS913903A patent/CS390391A3/cs unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FI834147A0 (fi) | 1983-11-11 |
| FI834147L (fi) | 1984-05-13 |
| IE56232B1 (en) | 1991-05-22 |
| ZA838436B (en) | 1985-06-26 |
| NO834093L (no) | 1984-05-14 |
| NO160782B (no) | 1989-02-20 |
| MX7314E (es) | 1988-05-11 |
| AU2118183A (en) | 1984-05-17 |
| EP0109284B1 (en) | 1989-01-11 |
| ES8504727A1 (es) | 1985-05-01 |
| PT77649B (en) | 1986-03-19 |
| DE3378912D1 (de) | 1989-02-16 |
| ES527163A0 (es) | 1985-05-01 |
| IL70198A (en) | 1988-11-15 |
| KR890000864B1 (ko) | 1989-04-11 |
| NZ206233A (en) | 1986-10-08 |
| CA1280755C (en) | 1991-02-26 |
| PT77649A (en) | 1983-12-01 |
| IE832639L (en) | 1984-05-12 |
| US4472405A (en) | 1984-09-18 |
| AU568319B2 (en) | 1987-12-24 |
| ATE39926T1 (de) | 1989-01-15 |
| EP0109284A1 (en) | 1984-05-23 |
| GR79402B (cs) | 1984-10-22 |
| CS390391A3 (en) | 1992-09-16 |
| EG16492A (en) | 1994-11-30 |
| FI73213B (fi) | 1987-05-29 |
| FI73213C (fi) | 1987-09-10 |
| JPS59112969A (ja) | 1984-06-29 |
| CA1254568A (en) | 1989-05-23 |
| IN161391B (cs) | 1987-11-28 |
| JPH0826017B2 (ja) | 1996-03-13 |
| NO160782C (no) | 1989-05-31 |
| IL70198A0 (en) | 1984-02-29 |
| KR840006659A (ko) | 1984-12-01 |
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