NZ741082A - C4-modified oleanolic acid derivatives for inhibition of il-17 and other uses - Google Patents

C4-modified oleanolic acid derivatives for inhibition of il-17 and other uses

Info

Publication number
NZ741082A
NZ741082A NZ741082A NZ74108216A NZ741082A NZ 741082 A NZ741082 A NZ 741082A NZ 741082 A NZ741082 A NZ 741082A NZ 74108216 A NZ74108216 A NZ 74108216A NZ 741082 A NZ741082 A NZ 741082A
Authority
NZ
New Zealand
Prior art keywords
acid derivatives
oleanolic acid
inhibition
obesity
disease
Prior art date
Application number
NZ741082A
Other languages
English (en)
Inventor
Xin Jiang
Melean Visnick
Bradley CAPRATHE
Chitase Lee
Gary Bolton
Martha Hotema
William Roark
Original Assignee
Reata Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reata Pharmaceuticals Inc filed Critical Reata Pharmaceuticals Inc
Publication of NZ741082A publication Critical patent/NZ741082A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyridine Compounds (AREA)
NZ741082A 2015-09-23 2016-09-23 C4-modified oleanolic acid derivatives for inhibition of il-17 and other uses NZ741082A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562222632P 2015-09-23 2015-09-23
PCT/US2016/053545 WO2017053868A1 (en) 2015-09-23 2016-09-23 C4-modified oleanolic acid derivatives for inhibition of il-17 and other uses

Publications (1)

Publication Number Publication Date
NZ741082A true NZ741082A (en) 2023-06-30

Family

ID=57137257

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ741082A NZ741082A (en) 2015-09-23 2016-09-23 C4-modified oleanolic acid derivatives for inhibition of il-17 and other uses

Country Status (14)

Country Link
US (2) US11584775B2 (enExample)
EP (1) EP3353190B1 (enExample)
JP (1) JP7074674B2 (enExample)
KR (1) KR102796889B1 (enExample)
CN (1) CN108290922B (enExample)
AU (1) AU2016326704B2 (enExample)
BR (1) BR112018005861B1 (enExample)
CA (1) CA2998681C (enExample)
EA (1) EA201890767A1 (enExample)
ES (1) ES2865163T3 (enExample)
IL (1) IL258185B (enExample)
MX (1) MX386256B (enExample)
NZ (1) NZ741082A (enExample)
WO (1) WO2017053868A1 (enExample)

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PL2892912T3 (pl) 2012-09-10 2019-10-31 Reata Pharmaceuticals Inc C17-alkanodiylowe i alkenodiylowe pochodne kwasu oleanolowego i sposoby ich zastosowania
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TWI649330B (zh) 2013-04-24 2019-02-01 艾伯維有限公司 甲基巴多索龍之２，２－二氟丙醯胺衍生物、其多晶形及其使用方法
EA201890767A1 (ru) 2015-09-23 2019-09-30 Рита Фармасьютикалз, Инк. C4-модифицированные производные олеаноловой кислоты для ингибирования il-17 и других применений
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CN108191944B (zh) * 2018-01-18 2020-12-11 华南师范大学 海洋微生物来源的二倍半萜AsperterpinolB衍生物及合成方法与糖酶应用
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CN109248168A (zh) * 2018-10-30 2019-01-22 武汉卫无忧生物科技有限公司 齐墩果酸在制备抗幽门螺杆菌的药物中的用途
TW202214648A (zh) 2019-01-07 2022-04-16 美商美國禮來大藥廠 Il-17a抑制劑
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Also Published As

Publication number Publication date
AU2016326704A1 (en) 2018-04-26
EA201890767A1 (ru) 2019-09-30
BR112018005861B1 (pt) 2022-11-22
WO2017053868A1 (en) 2017-03-30
CN108290922A (zh) 2018-07-17
EP3353190B1 (en) 2021-03-17
BR112018005861A2 (pt) 2018-10-16
US11584775B2 (en) 2023-02-21
IL258185A (en) 2018-05-31
CN108290922B (zh) 2021-12-07
US12545701B2 (en) 2026-02-10
KR20180061251A (ko) 2018-06-07
US20190153022A1 (en) 2019-05-23
HK1258095A1 (zh) 2019-11-01
MX2018003569A (es) 2018-11-29
KR102796889B1 (ko) 2025-04-17
US20230250130A1 (en) 2023-08-10
EP3353190A1 (en) 2018-08-01
JP7074674B2 (ja) 2022-05-24
AU2016326704B2 (en) 2021-01-28
ES2865163T3 (es) 2021-10-15
JP2018528275A (ja) 2018-09-27
CA2998681C (en) 2024-02-06
IL258185B (en) 2021-08-31
WO2017053868A8 (en) 2018-04-19
CA2998681A1 (en) 2017-03-30
MX386256B (es) 2025-03-18

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