NZ715111A - Process for improved opioid synthesis - Google Patents

Process for improved opioid synthesis

Info

Publication number
NZ715111A
NZ715111A NZ715111A NZ71511113A NZ715111A NZ 715111 A NZ715111 A NZ 715111A NZ 715111 A NZ715111 A NZ 715111A NZ 71511113 A NZ71511113 A NZ 71511113A NZ 715111 A NZ715111 A NZ 715111A
Authority
NZ
New Zealand
Prior art keywords
compositions
compounds
apis
preparation
improved opioid
Prior art date
Application number
NZ715111A
Other languages
English (en)
Inventor
Keith Mccarthy
Joshua R Giguere
Stuart James Gebbie
Lonn S Rider
Original Assignee
Rhodes Technologies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhodes Technologies filed Critical Rhodes Technologies
Publication of NZ715111A publication Critical patent/NZ715111A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
NZ715111A 2012-07-16 2013-07-15 Process for improved opioid synthesis NZ715111A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261672265P 2012-07-16 2012-07-16
US201361762657P 2013-02-08 2013-02-08
NZ628695A NZ628695A (en) 2012-07-16 2013-07-15 Process for improved opioid synthesis

Publications (1)

Publication Number Publication Date
NZ715111A true NZ715111A (en) 2016-12-23

Family

ID=48916126

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ715111A NZ715111A (en) 2012-07-16 2013-07-15 Process for improved opioid synthesis
NZ628695A NZ628695A (en) 2012-07-16 2013-07-15 Process for improved opioid synthesis

Family Applications After (1)

Application Number Title Priority Date Filing Date
NZ628695A NZ628695A (en) 2012-07-16 2013-07-15 Process for improved opioid synthesis

Country Status (21)

Country Link
US (4) US20150259355A1 (forum.php)
EP (1) EP2877473B1 (forum.php)
JP (1) JP6236446B2 (forum.php)
KR (1) KR101946104B1 (forum.php)
CN (1) CN104507947B (forum.php)
AR (1) AR091779A1 (forum.php)
AU (2) AU2013291723B2 (forum.php)
BR (1) BR112015000867A2 (forum.php)
CA (1) CA2879268C (forum.php)
CO (1) CO7180189A2 (forum.php)
EA (1) EA029925B1 (forum.php)
ES (1) ES2638178T3 (forum.php)
IL (1) IL236711B (forum.php)
IN (1) IN2015DN01164A (forum.php)
MX (1) MX362186B (forum.php)
NZ (2) NZ715111A (forum.php)
PH (1) PH12015500088A1 (forum.php)
SG (1) SG11201407986QA (forum.php)
TW (2) TWI588147B (forum.php)
UA (1) UA117226C2 (forum.php)
WO (1) WO2014013311A1 (forum.php)

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WO2014013311A1 (en) 2012-07-16 2014-01-23 Rhodes Technologies Process for improved opioid synthesis
UA117225C2 (uk) * 2012-07-16 2018-07-10 Родес Текнолоджіс Спосіб покращеного синтезу опіоїду
EP3083632A2 (en) 2013-12-18 2016-10-26 Cody Laboratories, Inc. Sysnthesis of oxycodone hydrochloride
US9062062B1 (en) 2013-12-18 2015-06-23 Cody Laboratories, Inc. Synthesis of oxycodone hydrochloride
US10227354B2 (en) 2013-12-18 2019-03-12 Cody Laboratories, Inc. Conversion of oxycodone base to oxycodone hydrochloride
US8846923B1 (en) 2013-12-18 2014-09-30 Cody Laboratories, Inc. Preparation of 14-hydroxycodeinone sulfate
JP2017502991A (ja) 2014-01-15 2017-01-26 ローズ テクノロジーズ 改良されたオキシコドン合成のための方法
ES2672795T3 (es) 2014-01-15 2018-06-18 Rhodes Technologies Proceso para la síntesis mejorada de oximorfona
US20160052932A1 (en) * 2014-08-25 2016-02-25 Johnson Matthey Public Limited Company Processes for Making Opioids Including 14-Hydroxycodeinone and 14-hydroxymorphinone
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KR102120720B1 (ko) * 2018-07-16 2020-06-10 연성정밀화학(주) 날푸라핀 함유 구강붕해정
CN114573508B (zh) * 2020-12-01 2024-07-23 绍兴赜军生物医药科技有限公司 羟考酮类化合物、其中间体及制备方法
US11247999B1 (en) 2021-07-02 2022-02-15 Joseph DeGraw Facile conversion of morphine to normorphine
CN114276358B (zh) * 2022-01-07 2023-09-12 北京华素制药股份有限公司 羟考酮盐酸盐的多晶型物及其制备方法和用途

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EP3083632A2 (en) 2013-12-18 2016-10-26 Cody Laboratories, Inc. Sysnthesis of oxycodone hydrochloride
US10227354B2 (en) 2013-12-18 2019-03-12 Cody Laboratories, Inc. Conversion of oxycodone base to oxycodone hydrochloride
ES2672795T3 (es) 2014-01-15 2018-06-18 Rhodes Technologies Proceso para la síntesis mejorada de oximorfona
JP2017502991A (ja) 2014-01-15 2017-01-26 ローズ テクノロジーズ 改良されたオキシコドン合成のための方法

Also Published As

Publication number Publication date
TW201416368A (zh) 2014-05-01
ES2638178T3 (es) 2017-10-19
EP2877473A1 (en) 2015-06-03
CN104507947A (zh) 2015-04-08
IN2015DN01164A (forum.php) 2015-06-26
CO7180189A2 (es) 2015-02-09
AR091779A1 (es) 2015-02-25
BR112015000867A2 (pt) 2019-10-15
PH12015500088B1 (en) 2015-03-02
US20150259355A1 (en) 2015-09-17
AU2013291723B2 (en) 2016-07-28
CA2879268C (en) 2018-05-08
WO2014013311A1 (en) 2014-01-23
IL236711A0 (en) 2015-02-26
JP6236446B2 (ja) 2017-11-22
EP2877473B1 (en) 2017-06-14
HK1210171A1 (en) 2016-04-15
KR101946104B1 (ko) 2019-02-08
CN104507947B (zh) 2017-06-27
US10202396B2 (en) 2019-02-12
SG11201407986QA (en) 2015-02-27
TW201639855A (zh) 2016-11-16
EA201590221A1 (ru) 2016-05-31
CA2879268A1 (en) 2014-01-23
US20180111946A1 (en) 2018-04-26
EA029925B1 (ru) 2018-05-31
US20190308986A1 (en) 2019-10-10
NZ628695A (en) 2016-02-26
KR20150029753A (ko) 2015-03-18
AU2016204929A1 (en) 2016-08-04
UA117226C2 (uk) 2018-07-10
MX362186B (es) 2019-01-08
AU2013291723A1 (en) 2014-12-18
PH12015500088A1 (en) 2015-03-02
IL236711B (en) 2018-04-30
TWI588147B (zh) 2017-06-21
US20210094964A1 (en) 2021-04-01
US11390627B2 (en) 2022-07-19
JP2015524406A (ja) 2015-08-24
MX2015000880A (es) 2016-09-07

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