UA117225C2 - Спосіб покращеного синтезу опіоїду - Google Patents

Спосіб покращеного синтезу опіоїду

Info

Publication number
UA117225C2
UA117225C2 UAA201501303A UAA201501303A UA117225C2 UA 117225 C2 UA117225 C2 UA 117225C2 UA A201501303 A UAA201501303 A UA A201501303A UA A201501303 A UAA201501303 A UA A201501303A UA 117225 C2 UA117225 C2 UA 117225C2
Authority
UA
Ukraine
Prior art keywords
compositions
compounds
apis
preparation
improved opioid
Prior art date
Application number
UAA201501303A
Other languages
English (en)
Inventor
Кейт МакКарті
Джошуа Р. Джіджуері
Стюарт Джеймс Джеббіе
Лонн С. Райдер
Original Assignee
Родес Текнолоджіс
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Родес Текнолоджіс filed Critical Родес Текнолоджіс
Publication of UA117225C2 publication Critical patent/UA117225C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Addiction (AREA)
  • Psychiatry (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Сполуки та композиції для застосування як вихідних матеріалів або проміжних матеріалів у виробництві опіоїдів, включаючи, наприклад, основу оксиморфону та/або сіль оксиморфону; способи одержання цих сполук та композицій; застосування цих сполук та композицій у виробництві АРІ та фармацевтичних дозованих форм; та застосування вказаних АРІ та фармацевтичних дозованих форм у лікуванні медичних станів.
UAA201501303A 2012-07-16 2013-07-15 Спосіб покращеного синтезу опіоїду UA117225C2 (uk)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261672260P 2012-07-16 2012-07-16
US201261741480P 2012-07-19 2012-07-19
US201361762637P 2013-02-08 2013-02-08
PCT/IB2013/001541 WO2014013313A1 (en) 2012-07-16 2013-07-15 Process for improved opioid synthesis

Publications (1)

Publication Number Publication Date
UA117225C2 true UA117225C2 (uk) 2018-07-10

Family

ID=48916127

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201501303A UA117225C2 (uk) 2012-07-16 2013-07-15 Спосіб покращеного синтезу опіоїду

Country Status (22)

Country Link
US (3) US10316042B2 (uk)
EP (1) EP2872516B1 (uk)
JP (1) JP6236447B2 (uk)
KR (1) KR101946103B1 (uk)
CN (1) CN104470928B (uk)
AR (1) AR092858A1 (uk)
AU (2) AU2013291725B2 (uk)
BR (1) BR112015000944A2 (uk)
CA (2) CA2974010A1 (uk)
CO (1) CO7180188A2 (uk)
EA (1) EA028092B1 (uk)
ES (1) ES2647949T3 (uk)
HK (1) HK1210170A1 (uk)
IL (1) IL236710B (uk)
IN (1) IN2015DN01165A (uk)
MX (1) MX363610B (uk)
NZ (1) NZ628699A (uk)
PH (1) PH12015500089A1 (uk)
SG (1) SG11201407988UA (uk)
TW (2) TWI643859B (uk)
UA (1) UA117225C2 (uk)
WO (1) WO2014013313A1 (uk)

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US10935314B2 (en) * 2019-03-21 2021-03-02 Evan Prout Heating values of cellulosic waste
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Also Published As

Publication number Publication date
CA2879270A1 (en) 2014-01-23
AU2013291725A1 (en) 2014-12-18
IL236710A0 (en) 2015-02-26
IN2015DN01165A (uk) 2015-06-26
JP6236447B2 (ja) 2017-11-22
PH12015500089B1 (en) 2015-03-02
TWI643859B (zh) 2018-12-11
EP2872516A1 (en) 2015-05-20
TW201641502A (zh) 2016-12-01
TW201416369A (zh) 2014-05-01
US20150315203A1 (en) 2015-11-05
IL236710B (en) 2018-04-30
KR101946103B1 (ko) 2019-02-08
EP2872516B1 (en) 2017-08-30
HK1210170A1 (en) 2016-04-15
EA201590222A1 (ru) 2015-05-29
MX363610B (es) 2019-03-28
JP2015524407A (ja) 2015-08-24
AU2016204926A1 (en) 2016-07-28
ES2647949T3 (es) 2017-12-27
US20230130617A1 (en) 2023-04-27
WO2014013313A1 (en) 2014-01-23
CA2879270C (en) 2017-09-05
TWI643860B (zh) 2018-12-11
BR112015000944A2 (pt) 2019-10-15
CO7180188A2 (es) 2015-02-09
EA028092B1 (ru) 2017-10-31
CN104470928A (zh) 2015-03-25
AR092858A1 (es) 2015-05-06
CN104470928B (zh) 2017-08-11
KR20150029752A (ko) 2015-03-18
CA2974010A1 (en) 2014-01-23
NZ628699A (en) 2016-05-27
US20190367526A1 (en) 2019-12-05
AU2013291725B2 (en) 2016-07-28
PH12015500089A1 (en) 2015-03-02
MX2015000879A (es) 2017-02-14
SG11201407988UA (en) 2015-01-29
US10316042B2 (en) 2019-06-11

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