MX362186B - Proceso de sintesis de opioides mejorado. - Google Patents

Proceso de sintesis de opioides mejorado.

Info

Publication number
MX362186B
MX362186B MX2015000880A MX2015000880A MX362186B MX 362186 B MX362186 B MX 362186B MX 2015000880 A MX2015000880 A MX 2015000880A MX 2015000880 A MX2015000880 A MX 2015000880A MX 362186 B MX362186 B MX 362186B
Authority
MX
Mexico
Prior art keywords
compositions
compounds
apis
preparation
improved opioid
Prior art date
Application number
MX2015000880A
Other languages
English (en)
Other versions
MX2015000880A (es
Inventor
Mccarthy Keith
R Giguere Joshua
James Gebbie Stuart
S Rider Lonn
Original Assignee
Rhodes Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhodes Tech filed Critical Rhodes Tech
Publication of MX2015000880A publication Critical patent/MX2015000880A/es
Publication of MX362186B publication Critical patent/MX362186B/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
    • C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
    • C07D489/08—Oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

Compuestos y composiciones para el uso como materiales de partida o materiales intermediarios en la preparación de opioides incluyendo, por ejemplo, base de oxicodona y/o una sal de oxicodona; procesos para preparar estos compuestos y composiciones; usos de estos compuestos y composiciones en la preparación de APIs y formas de dosis farmacéuticas; y usos de dichas APIs y formas de dosis farmacéuticas en el tratamiento de condiciones médicas.
MX2015000880A 2012-07-16 2013-07-15 Proceso de sintesis de opioides mejorado. MX362186B (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261672265P 2012-07-16 2012-07-16
US201361762657P 2013-02-08 2013-02-08
PCT/IB2013/001538 WO2014013311A1 (en) 2012-07-16 2013-07-15 Process for improved opioid synthesis

Publications (2)

Publication Number Publication Date
MX2015000880A MX2015000880A (es) 2016-09-07
MX362186B true MX362186B (es) 2019-01-08

Family

ID=48916126

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2015000880A MX362186B (es) 2012-07-16 2013-07-15 Proceso de sintesis de opioides mejorado.

Country Status (22)

Country Link
US (4) US20150259355A1 (es)
EP (1) EP2877473B1 (es)
JP (1) JP6236446B2 (es)
KR (1) KR101946104B1 (es)
CN (1) CN104507947B (es)
AR (1) AR091779A1 (es)
AU (2) AU2013291723B2 (es)
BR (1) BR112015000867A2 (es)
CA (1) CA2879268C (es)
CO (1) CO7180189A2 (es)
EA (1) EA029925B1 (es)
ES (1) ES2638178T3 (es)
HK (1) HK1210171A1 (es)
IL (1) IL236711B (es)
IN (1) IN2015DN01164A (es)
MX (1) MX362186B (es)
NZ (2) NZ628695A (es)
PH (1) PH12015500088B1 (es)
SG (1) SG11201407986QA (es)
TW (2) TW201639855A (es)
UA (1) UA117226C2 (es)
WO (1) WO2014013311A1 (es)

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AU2013291723B2 (en) 2012-07-16 2016-07-28 Rhodes Technologies Process for improved opioid synthesis
CA2879270C (en) * 2012-07-16 2017-09-05 Rhodes Technologies Process for improved opioid synthesis
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AU2015207733A1 (en) 2014-01-15 2016-07-14 Rhodes Technologies Process for improved oxycodone synthesis
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EP3642207B1 (en) 2017-06-20 2022-08-31 Johnson Matthey Public Limited Company Hydrogenation process for preparing oxycodone hydrochloride from 14-hydroxycodeinone
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Also Published As

Publication number Publication date
MX2015000880A (es) 2016-09-07
CN104507947B (zh) 2017-06-27
US20180111946A1 (en) 2018-04-26
US20190308986A1 (en) 2019-10-10
JP2015524406A (ja) 2015-08-24
IL236711A0 (en) 2015-02-26
IN2015DN01164A (es) 2015-06-26
SG11201407986QA (en) 2015-02-27
IL236711B (en) 2018-04-30
KR101946104B1 (ko) 2019-02-08
US20210094964A1 (en) 2021-04-01
CN104507947A (zh) 2015-04-08
NZ715111A (en) 2016-12-23
TW201416368A (zh) 2014-05-01
JP6236446B2 (ja) 2017-11-22
EA029925B1 (ru) 2018-05-31
CA2879268A1 (en) 2014-01-23
AU2016204929A1 (en) 2016-08-04
ES2638178T3 (es) 2017-10-19
AR091779A1 (es) 2015-02-25
CA2879268C (en) 2018-05-08
AU2013291723A1 (en) 2014-12-18
EP2877473A1 (en) 2015-06-03
TW201639855A (zh) 2016-11-16
TWI588147B (zh) 2017-06-21
PH12015500088A1 (en) 2015-03-02
NZ628695A (en) 2016-02-26
US11390627B2 (en) 2022-07-19
PH12015500088B1 (en) 2015-03-02
US20150259355A1 (en) 2015-09-17
UA117226C2 (uk) 2018-07-10
BR112015000867A2 (pt) 2019-10-15
WO2014013311A1 (en) 2014-01-23
HK1210171A1 (en) 2016-04-15
EA201590221A1 (ru) 2016-05-31
KR20150029753A (ko) 2015-03-18
CO7180189A2 (es) 2015-02-09
EP2877473B1 (en) 2017-06-14
AU2013291723B2 (en) 2016-07-28
US10202396B2 (en) 2019-02-12

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