NZ598468A - Floating microgranules - Google Patents

Floating microgranules

Info

Publication number
NZ598468A
NZ598468A NZ598468A NZ59846810A NZ598468A NZ 598468 A NZ598468 A NZ 598468A NZ 598468 A NZ598468 A NZ 598468A NZ 59846810 A NZ59846810 A NZ 59846810A NZ 598468 A NZ598468 A NZ 598468A
Authority
NZ
New Zealand
Prior art keywords
active ingredient
alkaline agent
group
core
carbonate
Prior art date
Application number
NZ598468A
Other languages
English (en)
Inventor
Pascal Suplie
Christophe Lebon
Original Assignee
Debregeas Et Associes Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debregeas Et Associes Pharma filed Critical Debregeas Et Associes Pharma
Publication of NZ598468A publication Critical patent/NZ598468A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/155Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/63Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005Wall or coating material
    • A61K9/5021Organic macromolecular compounds
    • A61K9/5026Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Physiology (AREA)
  • Nutrition Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Obesity (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Manufacture Of Metal Powder And Suspensions Thereof (AREA)
  • Glanulating (AREA)
NZ598468A 2009-08-12 2010-08-11 Floating microgranules NZ598468A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0955641A FR2949061B1 (fr) 2009-08-12 2009-08-12 Microgranules flottants
PCT/FR2010/051691 WO2011018582A2 (fr) 2009-08-12 2010-08-11 Microgranulés flottants

Publications (1)

Publication Number Publication Date
NZ598468A true NZ598468A (en) 2015-05-29

Family

ID=42115979

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ598468A NZ598468A (en) 2009-08-12 2010-08-11 Floating microgranules

Country Status (34)

Country Link
US (1) US8916202B2 (https=)
EP (1) EP2464333B1 (https=)
JP (1) JP6068142B2 (https=)
KR (2) KR20170119743A (https=)
CN (1) CN102548541B (https=)
AR (1) AR077864A1 (https=)
AU (1) AU2010283608B9 (https=)
BR (1) BR112012003289B1 (https=)
CA (1) CA2771053C (https=)
CL (1) CL2012000376A1 (https=)
CY (1) CY1118119T1 (https=)
DK (1) DK2464333T3 (https=)
EA (1) EA023532B1 (https=)
ES (1) ES2588430T3 (https=)
FR (1) FR2949061B1 (https=)
HR (1) HRP20161149T1 (https=)
HU (1) HUE030027T2 (https=)
IL (1) IL218072A (https=)
IN (1) IN2012DN01864A (https=)
LT (1) LT2464333T (https=)
MA (1) MA33523B1 (https=)
MX (1) MX2012001878A (https=)
NZ (1) NZ598468A (https=)
PE (1) PE20120805A1 (https=)
PL (1) PL2464333T3 (https=)
PT (1) PT2464333T (https=)
SG (1) SG180305A1 (https=)
SI (1) SI2464333T1 (https=)
SM (1) SMT201600347B (https=)
TN (1) TN2012000068A1 (https=)
TW (1) TWI478731B (https=)
UA (1) UA107361C2 (https=)
WO (1) WO2011018582A2 (https=)
ZA (1) ZA201201711B (https=)

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FR2938431B1 (fr) 2008-11-14 2013-12-20 Debregeas Et Associes Pharma Nouvelle composition a base d'acide gamma-hydroxybutyrique
FR2949062B1 (fr) 2009-08-12 2011-09-02 Debregeas Et Associes Pharma Nouvelles formulations pharmaceutiques contre le mesusage des medicaments
US9272044B2 (en) 2010-06-08 2016-03-01 Indivior Uk Limited Injectable flowable composition buprenorphine
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UY37341A (es) 2016-07-22 2017-11-30 Flamel Ireland Ltd Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada
US12478604B1 (en) 2016-07-22 2025-11-25 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics
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WO2019126216A1 (en) 2017-12-18 2019-06-27 Tris Phama, Inc. Pharmaceutical compositions comprising a floating interpenetrating polymer network forming system
US11337919B2 (en) 2017-12-18 2022-05-24 Tris Pharma, Inc. Modified release drug powder composition comprising gastro-retentive RAFT forming systems having trigger pulse drug release
WO2019126214A1 (en) 2017-12-18 2019-06-27 Tris Pharma, Inc. Pharmaceutical composition comprising ghb gastro-retentive raft forming systems having trigger pulse drug release
CN113473980A (zh) 2019-03-01 2021-10-01 弗拉梅尔爱尔兰有限公司 在进食状态下具有改善的药代动力学的γ-羟基丁酸酯组合物
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US11583510B1 (en) 2022-02-07 2023-02-21 Flamel Ireland Limited Methods of administering gamma hydroxybutyrate formulations after a high-fat meal
US11779557B1 (en) 2022-02-07 2023-10-10 Flamel Ireland Limited Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics

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Also Published As

Publication number Publication date
HRP20161149T1 (hr) 2016-11-18
IN2012DN01864A (https=) 2015-08-21
AU2010283608B2 (en) 2015-07-30
MX2012001878A (es) 2012-06-01
US8916202B2 (en) 2014-12-23
CL2012000376A1 (es) 2013-01-04
JP6068142B2 (ja) 2017-01-25
PL2464333T3 (pl) 2016-12-30
CA2771053A1 (fr) 2011-02-17
WO2011018582A2 (fr) 2011-02-17
ZA201201711B (en) 2012-11-28
UA107361C2 (en) 2014-12-25
WO2011018582A3 (fr) 2011-05-19
PT2464333T (pt) 2016-10-03
MA33523B1 (fr) 2012-08-01
SMT201600347B (it) 2016-11-10
CY1118119T1 (el) 2017-06-28
IL218072A (en) 2016-08-31
SG180305A1 (en) 2012-06-28
BR112012003289A2 (pt) 2020-08-11
BR112012003289B1 (pt) 2021-07-13
EA023532B1 (ru) 2016-06-30
TW201127419A (en) 2011-08-16
CN102548541A (zh) 2012-07-04
CA2771053C (fr) 2017-05-02
KR20170119743A (ko) 2017-10-27
TN2012000068A1 (fr) 2013-09-19
KR20120050477A (ko) 2012-05-18
FR2949061A1 (fr) 2011-02-18
EP2464333A2 (fr) 2012-06-20
AR077864A1 (es) 2011-09-28
SI2464333T1 (sl) 2016-10-28
IL218072A0 (en) 2012-04-30
DK2464333T3 (en) 2016-10-03
JP2013501762A (ja) 2013-01-17
US20120207843A1 (en) 2012-08-16
ES2588430T3 (es) 2016-11-02
LT2464333T (lt) 2016-09-12
HK1172824A1 (en) 2013-05-03
EA201200269A1 (ru) 2012-11-30
CN102548541B (zh) 2015-03-11
HUE030027T2 (en) 2017-04-28
AU2010283608B9 (en) 2015-08-27
TWI478731B (zh) 2015-04-01
PE20120805A1 (es) 2012-07-25
FR2949061B1 (fr) 2013-04-19
AU2010283608A1 (en) 2012-03-29
EP2464333B1 (fr) 2016-06-29

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