AR077864A1 - Microgranulos flotantes - Google Patents
Microgranulos flotantesInfo
- Publication number
- AR077864A1 AR077864A1 ARP100102964A ARP100102964A AR077864A1 AR 077864 A1 AR077864 A1 AR 077864A1 AR P100102964 A ARP100102964 A AR P100102964A AR P100102964 A ARP100102964 A AR P100102964A AR 077864 A1 AR077864 A1 AR 077864A1
- Authority
- AR
- Argentina
- Prior art keywords
- carbonate
- sodium
- floating
- chosen
- group
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
Un granulado flotante que comprende un nucleo solido que da soporte a un principio activo como por ejemplo furosemida, nifedipina, metformina y que comprende también un compuesto susceptible de generar un desprendimiento gaseoso constituido por un agente alcalino, y procedimiento de preparacion del mismo. Reivindicacion 5: Granulado flotante de acuerdo con una cualquiera de las reivindicaciones 1 a 3, caracterizado porque el agente alcalino se elige entre el grupo constituido por carbonatos y bicarbonatos, y, en especial, se elige en el grupo constituido por bicarbonato de sodio, carbonato de sodio, carbonato de glicina de sodio, bicarbonato de potasio, carbonato de magnesio, carbonato de calcio.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR0955641A FR2949061B1 (fr) | 2009-08-12 | 2009-08-12 | Microgranules flottants |
Publications (1)
Publication Number | Publication Date |
---|---|
AR077864A1 true AR077864A1 (es) | 2011-09-28 |
Family
ID=42115979
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ARP100102964A AR077864A1 (es) | 2009-08-12 | 2010-08-12 | Microgranulos flotantes |
Country Status (35)
Country | Link |
---|---|
US (1) | US8916202B2 (es) |
EP (1) | EP2464333B1 (es) |
JP (1) | JP6068142B2 (es) |
KR (2) | KR20120050477A (es) |
CN (1) | CN102548541B (es) |
AR (1) | AR077864A1 (es) |
AU (1) | AU2010283608B9 (es) |
BR (1) | BR112012003289B1 (es) |
CA (1) | CA2771053C (es) |
CL (1) | CL2012000376A1 (es) |
CY (1) | CY1118119T1 (es) |
DK (1) | DK2464333T3 (es) |
EA (1) | EA023532B1 (es) |
ES (1) | ES2588430T3 (es) |
FR (1) | FR2949061B1 (es) |
HK (1) | HK1172824A1 (es) |
HR (1) | HRP20161149T1 (es) |
HU (1) | HUE030027T2 (es) |
IL (1) | IL218072A (es) |
IN (1) | IN2012DN01864A (es) |
LT (1) | LT2464333T (es) |
MA (1) | MA33523B1 (es) |
MX (1) | MX2012001878A (es) |
NZ (1) | NZ598468A (es) |
PE (1) | PE20120805A1 (es) |
PL (1) | PL2464333T3 (es) |
PT (1) | PT2464333T (es) |
SG (1) | SG180305A1 (es) |
SI (1) | SI2464333T1 (es) |
SM (1) | SMT201600347B (es) |
TN (1) | TN2012000068A1 (es) |
TW (1) | TWI478731B (es) |
UA (1) | UA107361C2 (es) |
WO (1) | WO2011018582A2 (es) |
ZA (1) | ZA201201711B (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8852638B2 (en) | 2005-09-30 | 2014-10-07 | Durect Corporation | Sustained release small molecule drug formulation |
NZ581862A (en) | 2007-05-25 | 2012-06-29 | Tolmar Therapeutics Inc | Injectable subcutaneous formulation comprising risperidone capable of forming a solid, microporous implant in a patient |
FR2938431B1 (fr) | 2008-11-14 | 2013-12-20 | Debregeas Et Associes Pharma | Nouvelle composition a base d'acide gamma-hydroxybutyrique |
FR2949062B1 (fr) | 2009-08-12 | 2011-09-02 | Debregeas Et Associes Pharma | Nouvelles formulations pharmaceutiques contre le mesusage des medicaments |
GB2481017B (en) | 2010-06-08 | 2015-01-07 | Rb Pharmaceuticals Ltd | Microparticle buprenorphine suspension |
US9272044B2 (en) | 2010-06-08 | 2016-03-01 | Indivior Uk Limited | Injectable flowable composition buprenorphine |
US9321956B2 (en) | 2012-11-28 | 2016-04-26 | Halliburton Energy Services, Inc. | Methods for hindering the settling of particulates in a subterranean formation |
US9790774B2 (en) | 2014-01-02 | 2017-10-17 | Halliburton Energy Services, Inc. | Generating and maintaining conductivity of microfractures in tight formations by generating gas and heat |
GB201404139D0 (en) | 2014-03-10 | 2014-04-23 | Rb Pharmaceuticals Ltd | Sustained release buprenorphine solution formulations |
WO2017018998A1 (en) | 2015-07-24 | 2017-02-02 | Halliburton Energy Services, Inc. | Microbubbles for treatment chemical delivery in subterranean formations |
WO2017018996A1 (en) | 2015-07-24 | 2017-02-02 | Halliburton Energy Services, Inc. | Microbubbles for heat and/or gas generation in subterranean formations |
US11602513B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
UY37341A (es) | 2016-07-22 | 2017-11-30 | Flamel Ireland Ltd | Formulaciones de gamma-hidroxibutirato de liberación modificada con farmacocinética mejorada |
US11504347B1 (en) | 2016-07-22 | 2022-11-22 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US11602512B1 (en) | 2016-07-22 | 2023-03-14 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
WO2019126218A1 (en) * | 2017-12-18 | 2019-06-27 | Tris Pharma, Inc. | Modified release drug powder composition comprising gastro-retentive raft forming systems having trigger pulse drug release |
WO2019126215A1 (en) | 2017-12-18 | 2019-06-27 | Tris Pharma, Inc. | Ghb pharmaceutical compositions comprising a floating interpenetrating polymer network forming system |
US11400065B2 (en) | 2019-03-01 | 2022-08-02 | Flamel Ireland Limited | Gamma-hydroxybutyrate compositions having improved pharmacokinetics in the fed state |
NL2024652B1 (en) * | 2020-01-10 | 2021-09-07 | Stabican B V | Process for preparing cannabinoid-containing particles |
US11779557B1 (en) | 2022-02-07 | 2023-10-10 | Flamel Ireland Limited | Modified release gamma-hydroxybutyrate formulations having improved pharmacokinetics |
US11583510B1 (en) | 2022-02-07 | 2023-02-21 | Flamel Ireland Limited | Methods of administering gamma hydroxybutyrate formulations after a high-fat meal |
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JPS5276418A (en) * | 1975-12-19 | 1977-06-27 | Microbial Chem Res Found | Method of preparing foamable micro-capsule preparations |
US4101650A (en) * | 1977-04-06 | 1978-07-18 | Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai | Pepstatin floating minicapsules |
US4424235A (en) | 1981-09-14 | 1984-01-03 | Hoffmann-La Roche Inc. | Hydrodynamically balanced controlled release compositions containing L-dopa and a decarboxylase inhibitor |
JPS62195323A (ja) * | 1986-02-24 | 1987-08-28 | Eisai Co Ltd | 胃内滞留型粒子 |
IT1217783B (it) | 1988-06-03 | 1990-03-30 | Farmaceutico Ct S R L Lab | Impiego di salo dell,acido gamma idrossi butirrico per la preparazione di composizioni farmaceutiche adatta ad essereimpiegate nella terapia dell,alcolismo e composizioni relative |
IT1248588B (it) | 1991-06-28 | 1995-01-19 | Gaetano Crepaldi | Composizioni farmaceutiche per la terapia dell'astinenza, del " craving", della dipendenza da sostanze stupefacenti, da sostanze psicoattive, da nicotina e dei disturbi alimentari. |
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FR2762213B1 (fr) * | 1997-04-18 | 1999-05-14 | Synthelabo | Composition pharmaceutique a retention gastrique |
SE9702533D0 (sv) * | 1997-07-01 | 1997-07-01 | Astra Ab | New oral formulation |
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FR2797185B1 (fr) * | 1999-08-06 | 2001-10-26 | Galenix Dev | Composition pharmaceutique flottante comprenant une phase active et une phase non active |
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KR20040060917A (ko) | 2001-08-06 | 2004-07-06 | 유로-셀티크 소시에떼 아노뉨 | 오피오이드 남용을 방지하기 위한 조성물 및 방법 |
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FR2829932B1 (fr) | 2001-09-21 | 2006-11-24 | Ellipse Pharmaceuticals | Procede de fabrication d'un produit pharmaceutique administrable par voie orale avec des agents detrompeurs et produit obtenu |
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TWI350762B (en) | 2004-02-12 | 2011-10-21 | Euro Celtique Sa | Particulates |
US20050214371A1 (en) | 2004-03-03 | 2005-09-29 | Simona Di Capua | Stable pharmaceutical composition comprising an acid labile drug |
TW200533391A (en) * | 2004-03-25 | 2005-10-16 | Sun Pharmaceutical Ind Ltd | Gastric retention drug delivery system |
US8193211B2 (en) | 2004-09-30 | 2012-06-05 | Supernus Pharmaceuticals, Inc. | Controlled release compositions of gamma-hydroxybutyrate |
JP5095615B2 (ja) | 2005-06-27 | 2012-12-12 | バリアント・インターナショナル・(バルバドス)・ソサイアティーズ・ウィズ・リストリクティッド・ライアビリティ | ブプロピオン塩の放出調整製剤 |
PT1931315E (pt) * | 2005-08-24 | 2014-01-03 | Endo Pharmaceuticals Inc | Formulações de libertação sustentada de nalbufina |
US20070092565A1 (en) * | 2005-10-25 | 2007-04-26 | Pharmascience Inc. | Gastric retention drug delivery system |
WO2008134071A1 (en) | 2007-04-26 | 2008-11-06 | Theraquest Biosciences, Inc. | Multimodal abuse resistant extended release formulations |
EP1962844A2 (en) * | 2005-12-20 | 2008-09-03 | Teva Pharmaceutical Industries Ltd | Lansoprazole orally disintegrating tablets |
ZA200807571B (en) | 2006-03-01 | 2009-08-26 | Ethypharm Sa | Crush-resistant tablets intended to prevent accidental misuse and unlawful diversion |
US20090028941A1 (en) * | 2007-07-27 | 2009-01-29 | Depomed, Inc. | Pulsatile gastric retentive dosage forms |
EP2240022B1 (en) | 2008-01-09 | 2016-12-28 | Charleston Laboratories, Inc. | Bilayered tablets comprising oxycodone and promethazine |
FR2938431B1 (fr) | 2008-11-14 | 2013-12-20 | Debregeas Et Associes Pharma | Nouvelle composition a base d'acide gamma-hydroxybutyrique |
FR2949062B1 (fr) | 2009-08-12 | 2011-09-02 | Debregeas Et Associes Pharma | Nouvelles formulations pharmaceutiques contre le mesusage des medicaments |
-
2009
- 2009-08-12 FR FR0955641A patent/FR2949061B1/fr not_active Expired - Fee Related
-
2010
- 2010-08-11 SI SI201031271A patent/SI2464333T1/sl unknown
- 2010-08-11 AU AU2010283608A patent/AU2010283608B9/en active Active
- 2010-08-11 NZ NZ598468A patent/NZ598468A/en unknown
- 2010-08-11 ES ES10761038.8T patent/ES2588430T3/es active Active
- 2010-08-11 HU HUE10761038A patent/HUE030027T2/en unknown
- 2010-08-11 US US13/390,217 patent/US8916202B2/en active Active
- 2010-08-11 PL PL10761038.8T patent/PL2464333T3/pl unknown
- 2010-08-11 KR KR1020127006333A patent/KR20120050477A/ko active Application Filing
- 2010-08-11 LT LTEP10761038.8T patent/LT2464333T/lt unknown
- 2010-08-11 EP EP10761038.8A patent/EP2464333B1/fr active Active
- 2010-08-11 IN IN1864DEN2012 patent/IN2012DN01864A/en unknown
- 2010-08-11 PE PE2012000216A patent/PE20120805A1/es not_active Application Discontinuation
- 2010-08-11 JP JP2012524262A patent/JP6068142B2/ja active Active
- 2010-08-11 KR KR1020177030037A patent/KR20170119743A/ko not_active Application Discontinuation
- 2010-08-11 EA EA201200269A patent/EA023532B1/ru not_active IP Right Cessation
- 2010-08-11 CN CN201080044056.7A patent/CN102548541B/zh active Active
- 2010-08-11 CA CA2771053A patent/CA2771053C/fr active Active
- 2010-08-11 SG SG2012009965A patent/SG180305A1/en unknown
- 2010-08-11 DK DK10761038.8T patent/DK2464333T3/en active
- 2010-08-11 MX MX2012001878A patent/MX2012001878A/es active IP Right Grant
- 2010-08-11 PT PT107610388T patent/PT2464333T/pt unknown
- 2010-08-11 WO PCT/FR2010/051691 patent/WO2011018582A2/fr active Application Filing
- 2010-08-11 SM SM201600347T patent/SMT201600347B/it unknown
- 2010-08-11 BR BR112012003289-5A patent/BR112012003289B1/pt active IP Right Grant
- 2010-08-11 TW TW099126758A patent/TWI478731B/zh active
- 2010-08-12 AR ARP100102964A patent/AR077864A1/es unknown
- 2010-11-08 UA UAA201202667A patent/UA107361C2/ru unknown
-
2012
- 2012-02-13 MA MA34624A patent/MA33523B1/fr unknown
- 2012-02-13 CL CL2012000376A patent/CL2012000376A1/es unknown
- 2012-02-13 TN TNP2012000068A patent/TN2012000068A1/fr unknown
- 2012-02-13 IL IL218072A patent/IL218072A/en active IP Right Grant
- 2012-03-08 ZA ZA2012/01711A patent/ZA201201711B/en unknown
- 2012-12-31 HK HK12113624.3A patent/HK1172824A1/xx unknown
-
2016
- 2016-09-06 HR HRP20161149TT patent/HRP20161149T1/hr unknown
- 2016-09-26 CY CY20161100954T patent/CY1118119T1/el unknown
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