PE20120805A1 - Microgranulos flotantes - Google Patents

Microgranulos flotantes

Info

Publication number
PE20120805A1
PE20120805A1 PE2012000216A PE2012000216A PE20120805A1 PE 20120805 A1 PE20120805 A1 PE 20120805A1 PE 2012000216 A PE2012000216 A PE 2012000216A PE 2012000216 A PE2012000216 A PE 2012000216A PE 20120805 A1 PE20120805 A1 PE 20120805A1
Authority
PE
Peru
Prior art keywords
composition
total weight
amount
gum
agent
Prior art date
Application number
PE2012000216A
Other languages
English (en)
Inventor
Christophe Lebon
Pascal Suplie
Original Assignee
Debregeas Et Associes Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Debregeas Et Associes Pharma filed Critical Debregeas Et Associes Pharma
Publication of PE20120805A1 publication Critical patent/PE20120805A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0065—Forms with gastric retention, e.g. floating on gastric juice, adhering to gastric mucosa, expanding to prevent passage through the pylorus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

SE REFIERE A UN GRANULO FLOTANTE QUE COMPRENDE: A) UN NUCLEO SOLIDO SELECCIONADO ENTRE SOPORTES INSOLUBLES TALES COMO POLIOLES, GOMAS, FOSFATOS DICALCICOS, CELULOSA MONOCRISTALINA, ENTRE OTROS, EN UNA CANTIDAD DE 20% A 80% DEL PESO TOTAL DE LA COMPOSICION; B) UN INGREDIENTE ACTIVO QUE SE SOSTIENE EN EL NUCLEO SOLIDO TAL COMO ANALGESICOS Y ANTIALGICOS, EN UNA CANTIDAD DE 0.5% A 60% DEL PESO TOTAL DE LA COMPOSICION; C) UN AGENTE ALCALINO TAL COMO BICARBONATO DE SODIO, CARBONATO DE GLICINA SODICO, CARBONATO DE MAGNESIO, ENTRE OTROS, EN UNA CANTIDAD DE 15% A 70% DEL PESO TOTAL DE LA COMPOSICION; D) UN AGLOMERANTE TAL COMO MALTODEXTRINAS, ALMIDON, SACAROSA, GOMA ARABIGA, ENTRE OTROS; Y E) UN AGENTE DE RECUBRIMIENTO TAL COMO GOMA LACA, POLIVINILPIRROLIDONA, POLIETILENGLICOL, DERIVADOS DE CELULOSA, ENTRE OTROS. DICHA COMPOSICION NO COMPRENDE UN AGENTE ACIDO
PE2012000216A 2009-08-12 2010-08-11 Microgranulos flotantes PE20120805A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0955641A FR2949061B1 (fr) 2009-08-12 2009-08-12 Microgranules flottants

Publications (1)

Publication Number Publication Date
PE20120805A1 true PE20120805A1 (es) 2012-07-25

Family

ID=42115979

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2012000216A PE20120805A1 (es) 2009-08-12 2010-08-11 Microgranulos flotantes

Country Status (35)

Country Link
US (1) US8916202B2 (es)
EP (1) EP2464333B1 (es)
JP (1) JP6068142B2 (es)
KR (2) KR20120050477A (es)
CN (1) CN102548541B (es)
AR (1) AR077864A1 (es)
AU (1) AU2010283608B9 (es)
BR (1) BR112012003289B1 (es)
CA (1) CA2771053C (es)
CL (1) CL2012000376A1 (es)
CY (1) CY1118119T1 (es)
DK (1) DK2464333T3 (es)
EA (1) EA023532B1 (es)
ES (1) ES2588430T3 (es)
FR (1) FR2949061B1 (es)
HK (1) HK1172824A1 (es)
HR (1) HRP20161149T1 (es)
HU (1) HUE030027T2 (es)
IL (1) IL218072A (es)
IN (1) IN2012DN01864A (es)
LT (1) LT2464333T (es)
MA (1) MA33523B1 (es)
MX (1) MX2012001878A (es)
NZ (1) NZ598468A (es)
PE (1) PE20120805A1 (es)
PL (1) PL2464333T3 (es)
PT (1) PT2464333T (es)
SG (1) SG180305A1 (es)
SI (1) SI2464333T1 (es)
SM (1) SMT201600347B (es)
TN (1) TN2012000068A1 (es)
TW (1) TWI478731B (es)
UA (1) UA107361C2 (es)
WO (1) WO2011018582A2 (es)
ZA (1) ZA201201711B (es)

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Also Published As

Publication number Publication date
TN2012000068A1 (fr) 2013-09-19
IL218072A (en) 2016-08-31
PT2464333T (pt) 2016-10-03
CA2771053A1 (fr) 2011-02-17
CY1118119T1 (el) 2017-06-28
FR2949061A1 (fr) 2011-02-18
ZA201201711B (en) 2012-11-28
EA023532B1 (ru) 2016-06-30
AU2010283608B2 (en) 2015-07-30
CL2012000376A1 (es) 2013-01-04
UA107361C2 (en) 2014-12-25
EP2464333A2 (fr) 2012-06-20
AU2010283608B9 (en) 2015-08-27
JP6068142B2 (ja) 2017-01-25
IN2012DN01864A (es) 2015-08-21
HUE030027T2 (en) 2017-04-28
EP2464333B1 (fr) 2016-06-29
CN102548541B (zh) 2015-03-11
KR20120050477A (ko) 2012-05-18
WO2011018582A3 (fr) 2011-05-19
MA33523B1 (fr) 2012-08-01
WO2011018582A2 (fr) 2011-02-17
TWI478731B (zh) 2015-04-01
KR20170119743A (ko) 2017-10-27
CN102548541A (zh) 2012-07-04
JP2013501762A (ja) 2013-01-17
AR077864A1 (es) 2011-09-28
TW201127419A (en) 2011-08-16
HK1172824A1 (en) 2013-05-03
PL2464333T3 (pl) 2016-12-30
AU2010283608A1 (en) 2012-03-29
IL218072A0 (en) 2012-04-30
NZ598468A (en) 2015-05-29
LT2464333T (lt) 2016-09-12
SG180305A1 (en) 2012-06-28
CA2771053C (fr) 2017-05-02
SI2464333T1 (sl) 2016-10-28
HRP20161149T1 (hr) 2016-11-18
ES2588430T3 (es) 2016-11-02
EA201200269A1 (ru) 2012-11-30
FR2949061B1 (fr) 2013-04-19
BR112012003289B1 (pt) 2021-07-13
SMT201600347B (it) 2016-11-10
US8916202B2 (en) 2014-12-23
BR112012003289A2 (pt) 2020-08-11
DK2464333T3 (en) 2016-10-03
MX2012001878A (es) 2012-06-01
US20120207843A1 (en) 2012-08-16

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