NZ594370A - Carba-nucleoside analogs for antiviral treatment - Google Patents

Carba-nucleoside analogs for antiviral treatment

Info

Publication number
NZ594370A
NZ594370A NZ594370A NZ59437010A NZ594370A NZ 594370 A NZ594370 A NZ 594370A NZ 594370 A NZ594370 A NZ 594370A NZ 59437010 A NZ59437010 A NZ 59437010A NZ 594370 A NZ594370 A NZ 594370A
Authority
NZ
New Zealand
Prior art keywords
virus
formula
compound
disclosed
medicament
Prior art date
Application number
NZ594370A
Other languages
English (en)
Inventor
Aesop Cho
Choung U Kim
Jie Xu
Thomas Butler
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42333309&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ594370(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of NZ594370A publication Critical patent/NZ594370A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/24—Heterocyclic radicals containing oxygen or sulfur as ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/048—Pyridine radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NZ594370A 2009-02-10 2010-02-09 Carba-nucleoside analogs for antiviral treatment NZ594370A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15124809P 2009-02-10 2009-02-10
PCT/US2010/023586 WO2010093608A1 (en) 2009-02-10 2010-02-09 Carba-nucleoside analogs for antiviral treatment

Publications (1)

Publication Number Publication Date
NZ594370A true NZ594370A (en) 2014-01-31

Family

ID=42333309

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ594370A NZ594370A (en) 2009-02-10 2010-02-09 Carba-nucleoside analogs for antiviral treatment

Country Status (26)

Country Link
US (1) US8012942B2 (https=)
EP (2) EP2396340B1 (https=)
JP (2) JP5746638B2 (https=)
KR (2) KR101724759B1 (https=)
CN (1) CN102348713B (https=)
AP (1) AP2922A (https=)
AU (3) AU2010213873B2 (https=)
BR (1) BRPI1013643A2 (https=)
CA (1) CA2751277C (https=)
CL (1) CL2011001906A1 (https=)
CO (1) CO6420354A2 (https=)
DK (1) DK2396340T3 (https=)
EA (1) EA025085B1 (https=)
ES (2) ES2453078T3 (https=)
HR (1) HRP20140219T1 (https=)
IL (1) IL214396A (https=)
MX (2) MX2011008409A (https=)
NZ (1) NZ594370A (https=)
PE (3) PE20160858A1 (https=)
PL (1) PL2396340T3 (https=)
PT (2) PT2719701T (https=)
SG (1) SG173186A1 (https=)
SI (1) SI2396340T1 (https=)
SM (1) SMT201400056B (https=)
UA (2) UA112140C2 (https=)
WO (1) WO2010093608A1 (https=)

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Also Published As

Publication number Publication date
KR20110116046A (ko) 2011-10-24
WO2010093608A1 (en) 2010-08-19
UA112140C2 (uk) 2016-07-25
IL214396A0 (en) 2011-09-27
JP2014185183A (ja) 2014-10-02
PL2396340T3 (pl) 2014-05-30
CO6420354A2 (es) 2012-04-16
CL2011001906A1 (es) 2012-03-30
AP2011005818A0 (en) 2011-08-31
JP5746638B2 (ja) 2015-07-08
MX2011008409A (es) 2011-10-21
JP2012517444A (ja) 2012-08-02
AU2017202413A1 (en) 2017-05-04
AP2922A (en) 2014-05-31
EA201190110A1 (ru) 2012-02-28
PE20120257A1 (es) 2012-03-29
AU2010213873A1 (en) 2011-09-01
KR101834707B1 (ko) 2018-03-05
CA2751277C (en) 2018-10-30
MX345562B (es) 2017-02-03
JP5951690B2 (ja) 2016-07-13
EP2396340B1 (en) 2013-12-18
EP2719701B1 (en) 2017-04-05
IL214396A (en) 2014-07-31
KR20170039759A (ko) 2017-04-11
CN102348713A (zh) 2012-02-08
PT2719701T (pt) 2017-06-29
EA025085B1 (ru) 2016-11-30
HRP20140219T1 (hr) 2014-04-11
AU2015238785A1 (en) 2015-10-29
PT2396340E (pt) 2014-03-26
AU2010213873B2 (en) 2015-07-09
AU2015238785B2 (en) 2017-02-16
KR101724759B1 (ko) 2017-04-07
SMT201400056B (it) 2014-07-07
ES2628842T3 (es) 2017-08-04
HK1163108A1 (en) 2012-09-07
UA110093C2 (uk) 2015-11-25
PE20160858A1 (es) 2016-09-03
SI2396340T1 (sl) 2014-04-30
SG173186A1 (en) 2011-09-29
PE20161067A1 (es) 2016-10-23
DK2396340T3 (en) 2014-03-10
US20100203015A1 (en) 2010-08-12
AU2017202413B2 (en) 2018-09-13
EP2719701A1 (en) 2014-04-16
BRPI1013643A2 (pt) 2016-04-19
ES2453078T3 (es) 2014-04-03
US8012942B2 (en) 2011-09-06
EP2396340A1 (en) 2011-12-21
CA2751277A1 (en) 2010-08-19
CN102348713B (zh) 2015-12-02

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