WO2011041713A3 - Piperazinyl antiviral agents - Google Patents

Piperazinyl antiviral agents Download PDF

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Publication number
WO2011041713A3
WO2011041713A3 PCT/US2010/051175 US2010051175W WO2011041713A3 WO 2011041713 A3 WO2011041713 A3 WO 2011041713A3 US 2010051175 W US2010051175 W US 2010051175W WO 2011041713 A3 WO2011041713 A3 WO 2011041713A3
Authority
WO
WIPO (PCT)
Prior art keywords
antiviral agents
piperazinyl
piperazinyl antiviral
hcv
hepatitis
Prior art date
Application number
PCT/US2010/051175
Other languages
French (fr)
Other versions
WO2011041713A2 (en
Inventor
Anna Banka
John G. Catalano
Pek Yoke Chong
Jing Fang
Dulce Maria Garrido
Andrew James Peat
Daniel J. Price
John Brad Shotwell
Vincent Tai
Huichang Zhang
Original Assignee
Glaxosmithkline Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxosmithkline Llc filed Critical Glaxosmithkline Llc
Publication of WO2011041713A2 publication Critical patent/WO2011041713A2/en
Publication of WO2011041713A3 publication Critical patent/WO2011041713A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Abstract

Provided are compounds of Formula (I) and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and their use for treating viral infections mediated by a member of the Flaviviridae family of viruses such as hepatitis C virus (HCV).
PCT/US2010/051175 2009-10-02 2010-10-01 Piperazinyl antiviral agents WO2011041713A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24806309P 2009-10-02 2009-10-02
US61/248,063 2009-10-02

Publications (2)

Publication Number Publication Date
WO2011041713A2 WO2011041713A2 (en) 2011-04-07
WO2011041713A3 true WO2011041713A3 (en) 2012-04-05

Family

ID=43826913

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/051175 WO2011041713A2 (en) 2009-10-02 2010-10-01 Piperazinyl antiviral agents

Country Status (1)

Country Link
WO (1) WO2011041713A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013130703A2 (en) 2012-02-29 2013-09-06 Institute For Hepatitis And Virus Research Binhibitors of hepatitis b virus convalently closed circular dna formation and their method of use
CN102633657B (en) * 2012-03-30 2014-05-14 甘肃科瑞生物科技有限公司 Preparation method of cis-3-amino-cyclopentanol hydrochloride
CN103664639B (en) * 2013-11-19 2015-05-20 中国科学院广州生物医药与健康研究院 Amine compound, preparation method thereof and application of amine compound in preparation of anti-influenza virus medicine
WO2015099196A1 (en) 2013-12-26 2015-07-02 Takeda Pharmaceutical Company Limited 4-(piperrazin-1-yl)-pyrrolidin-2-one compounds as monoacylglycerol lipase (magl) inhibitors
BR112017006117A2 (en) 2014-09-26 2017-12-19 Changzhou Yinsheng Pharmaceutical Co Ltd benzofuran analog as ns4b inhibitor
WO2016160677A1 (en) * 2015-04-01 2016-10-06 Arisan Therapeutics Inc. Compounds for the treatment of arenavirus infection
WO2016162318A1 (en) 2015-04-08 2016-10-13 Bayer Cropscience Aktiengesellschaft Condensed bicyclic heterocycle derivatives as pest control agents and intermediate product
CN105732602B (en) * 2015-09-23 2017-04-19 常州寅盛药业有限公司 Benzofuran analogue used as NS4B inhibitor
JP6916175B2 (en) 2015-10-26 2021-08-11 バイエル・クロップサイエンス・アクチェンゲゼルシャフト Condensed bicyclic heterocyclic derivative as a pest control agent
WO2017093180A1 (en) 2015-12-01 2017-06-08 Bayer Cropscience Aktiengesellschaft Condensed bicyclic heterocycle derivatives as pest control agents
WO2017144341A1 (en) 2016-02-23 2017-08-31 Bayer Cropscience Aktiengesellschaft Condensed bicyclic heterocycle derivatives as pest control agents
EP3241830A1 (en) 2016-05-04 2017-11-08 Bayer CropScience Aktiengesellschaft Condensed bicyclic heterocyclic derivatives as pesticides
US11352328B2 (en) 2016-07-12 2022-06-07 Arisan Therapeutics Inc. Heterocyclic compounds for the treatment of arenavirus
ES2938615T3 (en) 2016-08-15 2023-04-13 Bayer Cropscience Ag Condensed bicyclic heterocycle derivatives as pest control agents
WO2018138050A1 (en) 2017-01-26 2018-08-02 Bayer Aktiengesellschaft Condensed bicyclic heterocyclene derivatives as pest control agents
US10981935B2 (en) 2017-10-04 2021-04-20 Bayer Aktiengesellschaft Heterocycle derivatives as pesticides
EP3755700B1 (en) 2018-02-21 2021-11-24 Bayer Aktiengesellschaft Condensed bicyclic heterocycle derivatives as pesticides
JP2021517148A (en) 2018-03-12 2021-07-15 バイエル・アクチエンゲゼルシヤフト Condensation bicyclic heterocyclic derivative as a pest control agent
US20210169080A1 (en) 2018-04-20 2021-06-10 Bayer Aktiengesellschaft Heterocycle derivatives as pesticides
US11512088B2 (en) 2019-01-30 2022-11-29 Avista Pharma Solutions, Inc. Synthetic process and intermediates

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005054247A1 (en) * 2003-11-26 2005-06-16 Bristol-Myers Squibb Company Diazaindole-dicarbonyl-piperazinyl antiviral agents
US20070043074A1 (en) * 2003-10-28 2007-02-22 Sepracor Inc. Imidazo[1,2-a] pyridine anxiolytics
US20070135451A1 (en) * 2001-06-21 2007-06-14 Gudmundsson Kristjan S Imidazo[1,2-a]Pyridine Derivatives for Treatment Of Herpes Viral Infections
US20080188515A1 (en) * 2005-04-25 2008-08-07 Michael Thormann Imidazo [1,2-A] Pyridine Derivatives Useful As Peptide Deformylase (Pdf) Inhibitors
WO2009023179A2 (en) * 2007-08-10 2009-02-19 Genelabs Technologies, Inc. Nitrogen containing bicyclic chemical entities for treating viral infections

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070135451A1 (en) * 2001-06-21 2007-06-14 Gudmundsson Kristjan S Imidazo[1,2-a]Pyridine Derivatives for Treatment Of Herpes Viral Infections
US20070043074A1 (en) * 2003-10-28 2007-02-22 Sepracor Inc. Imidazo[1,2-a] pyridine anxiolytics
WO2005054247A1 (en) * 2003-11-26 2005-06-16 Bristol-Myers Squibb Company Diazaindole-dicarbonyl-piperazinyl antiviral agents
US20080188515A1 (en) * 2005-04-25 2008-08-07 Michael Thormann Imidazo [1,2-A] Pyridine Derivatives Useful As Peptide Deformylase (Pdf) Inhibitors
WO2009023179A2 (en) * 2007-08-10 2009-02-19 Genelabs Technologies, Inc. Nitrogen containing bicyclic chemical entities for treating viral infections

Also Published As

Publication number Publication date
WO2011041713A2 (en) 2011-04-07

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