NZ583851A - Use of slit, nephrin, ephrin or semaphorin for treatment of cartilage diseases - Google Patents

Use of slit, nephrin, ephrin or semaphorin for treatment of cartilage diseases

Info

Publication number
NZ583851A
NZ583851A NZ583851A NZ58385108A NZ583851A NZ 583851 A NZ583851 A NZ 583851A NZ 583851 A NZ583851 A NZ 583851A NZ 58385108 A NZ58385108 A NZ 58385108A NZ 583851 A NZ583851 A NZ 583851A
Authority
NZ
New Zealand
Prior art keywords
cartilage
cells
slit3
pharmaceutical composition
repellent
Prior art date
Application number
NZ583851A
Other languages
English (en)
Inventor
Anja Bosserhoff
Thomas Schubert
Elisabeth Hustert
Original Assignee
Formycon Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP07018131A external-priority patent/EP2036921A1/en
Application filed by Formycon Gmbh filed Critical Formycon Gmbh
Publication of NZ583851A publication Critical patent/NZ583851A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Rheumatology (AREA)
  • Neurology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Psychiatry (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NZ583851A 2007-09-14 2008-09-12 Use of slit, nephrin, ephrin or semaphorin for treatment of cartilage diseases NZ583851A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP07018131A EP2036921A1 (en) 2007-09-14 2007-09-14 Use of Slit, nephrin, ephrin or semaphorin for treatment of cartilage diseases
EP08006810 2008-04-03
PCT/EP2008/007579 WO2009033715A2 (en) 2007-09-14 2008-09-12 Neuroendocrine factors for treatment of degenerative diseases

Publications (1)

Publication Number Publication Date
NZ583851A true NZ583851A (en) 2012-06-29

Family

ID=40452588

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ583851A NZ583851A (en) 2007-09-14 2008-09-12 Use of slit, nephrin, ephrin or semaphorin for treatment of cartilage diseases

Country Status (13)

Country Link
US (1) US20110002972A1 (enExample)
EP (1) EP2212344B1 (enExample)
JP (1) JP2010539123A (enExample)
KR (1) KR20100075493A (enExample)
CN (1) CN101821283A (enExample)
AU (1) AU2008297889A1 (enExample)
BR (1) BRPI0816784A8 (enExample)
CA (1) CA2699411A1 (enExample)
MX (1) MX2010002716A (enExample)
NZ (1) NZ583851A (enExample)
RU (1) RU2496790C2 (enExample)
WO (1) WO2009033715A2 (enExample)
ZA (1) ZA201001644B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1400024B1 (it) * 2010-05-21 2013-05-17 Uni Politecnica Delle Marche Uso farmaceutico di semaforine.
AR084541A1 (es) * 2010-12-23 2013-05-22 Sanofi Sa PROTEINA DE FUSION ROBO1-Fc PARA SU USO EN EL TRATAMIENTO DEL HEPATOCARCINOMA
EP3653218B1 (en) * 2011-07-04 2024-12-18 Mesoblast, Inc. Treating or preventing rheumatic disease
WO2013187730A1 (ko) * 2012-06-15 2013-12-19 재단법인 아산사회복지재단 Slit-Robo 시스템을 이용한 골절 또는 골다공증의 예방 또는 치료용 조성물
ES2442242B1 (es) * 2012-08-09 2014-11-25 Biotechnology Institute, I Mas D, S.L. Composición con factores de crecimiento destinada al tratamiento intranasal de una enfermedad neurodegenerativa u otra patología del sistema nervioso central, y su método de fabricación.
CN104119445A (zh) * 2013-04-26 2014-10-29 李华顺 含有富含亮氨酸重复序列的融合蛋白及其制法和应用
CN104119446A (zh) * 2013-04-26 2014-10-29 李华顺 含有富含亮氨酸重复序列的融合蛋白及其制法和应用
CN104119447A (zh) * 2013-04-26 2014-10-29 李华顺 含有富含亮氨酸重复序列的融合蛋白及其制法和应用
CN104119448A (zh) * 2013-04-26 2014-10-29 李华顺 含有富含亮氨酸重复序列的融合蛋白及其制法和应用
JPWO2015072527A1 (ja) * 2013-11-13 2017-03-16 国立大学法人大阪大学 ネトリン1含有破骨細胞形成抑制剤
PL3116521T3 (pl) 2014-03-14 2024-12-16 The Research Foundation For The State University Of New York Neurogeniczna regulacja wzrostu i degradacji kości
US11052175B2 (en) 2015-08-19 2021-07-06 Musculoskeletal Transplant Foundation Cartilage-derived implants and methods of making and using same
US20200397860A1 (en) * 2018-02-14 2020-12-24 Cornell University Slit and bone growth modulation
BR112021016948A2 (pt) * 2019-02-27 2021-11-03 Daewoong Pharmaceutical Co Ltd Composição que compreende lrrd2 ligado à albumina de proteína slit3 para prevenção ou tratamento de doenças relacionadas a ossos e uso de lrrd2 ligado à albumina da proteína slit3
KR20220079857A (ko) * 2019-09-13 2022-06-14 루트거스, 더 스테이트 유니버시티 오브 뉴 저지 Aav-상용성 라미닌-링커 중합 단백질
CN110841057B (zh) * 2019-11-19 2023-08-01 四川大学华西医院 一种神经导向因子Sema在制备治疗骨关节炎巴布膏剂中的应用
CN110772632B (zh) * 2019-11-19 2023-08-11 四川大学华西医院 神经导向因子semaphorin 3a在制备治疗骨关节炎药物中的用途
CN110711244B (zh) * 2019-11-19 2023-08-01 四川大学华西医院 一种神经导向因子Sema在制备治疗骨关节炎搽剂中的应用
CN110684805B (zh) * 2019-11-19 2023-08-01 四川大学华西医院 神经导向因子Sema基因重组慢病毒载体在制备治疗骨关节炎药物中的应用
CN110721308B (zh) * 2019-11-19 2023-08-01 四川大学华西医院 一种用于治疗骨关节炎的药物复方制剂及其制备方法
CN110694051B (zh) * 2019-11-19 2023-08-01 四川大学华西医院 一种神经导向因子Sema在制备治疗骨关节炎注射剂中的应用
US20240277861A1 (en) * 2021-07-26 2024-08-22 Purotech Bio, Inc. Anti-hepatitis b virus agent targeting host factor lipg

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2700117B1 (fr) * 1993-01-07 1995-02-03 Rhone Poulenc Rorer Sa Application d'anticonvulsivants dans le traitement de la maladie de Parkinson et des syndromes parkinsoniens.
JPH1116490A (ja) * 1997-06-26 1999-01-22 Kyocera Corp プラズマディスプレイパネル用隔壁の製造方法及びプラズマディスプレイパネル用基板
US20030032057A1 (en) * 1997-08-26 2003-02-13 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US6342370B1 (en) * 1997-10-31 2002-01-29 Osiris Therapeutics, Inc. Human slit polypeptide and polynucleotides encoding same
JPH11164690A (ja) * 1997-12-05 1999-06-22 Asahi Chem Ind Co Ltd 脊椎動物スリット蛋白質
US6924355B2 (en) * 1998-09-01 2005-08-02 Genentech, Inc. PRO1343 polypeptides
AU3755100A (en) * 1999-03-17 2000-10-04 Washington University Vertebrate slit dna sequence, protein and uses thereof
AU2001278655A1 (en) * 2000-07-18 2002-01-30 Compugen Ltd. Novel nucleic acid and amino acid sequences
EP1307557A2 (en) * 2000-08-02 2003-05-07 The Johns Hopkins University Endothelial cell expression patterns
CA2423519A1 (en) * 2000-08-10 2002-02-14 Pharmacia Corporation A new slit-like protein obtained from a cdna library from hs-5 stromal cell line
WO2002081745A2 (en) * 2001-04-05 2002-10-17 Proskelia Pharmaceuticals Genes involved in osteogenesis, and methods of use
US20050014680A1 (en) * 2003-04-15 2005-01-20 Crabtree Gerald R. Methods and compositions for enhancing neuron growth and survival
US20060025335A1 (en) * 2004-01-30 2006-02-02 Kinane Thomas B Netrin compositions and methods of using the same
CN101600451A (zh) * 2006-12-11 2009-12-09 犹他大学研究基金会 用于治疗病理性血管生成和血管通透性的组合物和方法

Also Published As

Publication number Publication date
BRPI0816784A2 (pt) 2015-03-24
BRPI0816784A8 (pt) 2016-01-19
WO2009033715A2 (en) 2009-03-19
AU2008297889A1 (en) 2009-03-19
MX2010002716A (es) 2010-07-05
RU2010114713A (ru) 2011-10-20
RU2496790C2 (ru) 2013-10-27
ZA201001644B (en) 2011-03-30
EP2212344B1 (en) 2014-03-26
EP2212344A2 (en) 2010-08-04
KR20100075493A (ko) 2010-07-02
WO2009033715A3 (en) 2010-03-18
US20110002972A1 (en) 2011-01-06
CN101821283A (zh) 2010-09-01
JP2010539123A (ja) 2010-12-16
CA2699411A1 (en) 2009-03-19

Similar Documents

Publication Publication Date Title
EP2212344B1 (en) Use of slit, nephrin, ephrin or semaphorin for treatment of cartilage diseases
Cucchiarini et al. Gene therapy for cartilage defects
KR100898765B1 (ko) 성장인자 복합체
KR100688871B1 (ko) 연골세포 및 TGF-β를 사용한 연골 재생
Song et al. Hyaline cartilage regeneration using mixed human chondrocytes and transforming growth factor-β1-producing chondrocytes
Madry et al. Clinical potential and challenges of using genetically modified cells for articular cartilage repair
US20250345393A1 (en) Isoform nell-1 peptide
US8691944B2 (en) Fibronectin polypeptides and methods of use
US20140057842A1 (en) Compositions and methods for cell homing and adipogenesis
EP2036921A1 (en) Use of Slit, nephrin, ephrin or semaphorin for treatment of cartilage diseases
KR100702725B1 (ko) Tgf-베타를 사용하는 유전자 요법
AU2006235200A1 (en) Use of Neuropeptide Y (NPY) and agonists and antagonists thereof for tissue regeneration
WO2012094511A2 (en) Compositions and methods for the treatment of orthopedic disease or injury
Aihaiti et al. The role of thrombospondins in osteoarthritis: from molecular mechanisms to therapeutic potential
WO2010135915A1 (zh) 中期因子蛋白的用途及含该蛋白的医用装置
US20140073765A1 (en) Regeneration and repair of mesenchymal tissue using amelogenin
US20120208753A1 (en) Composition and Method for the Treatment or Prevention of Spinal Disorders III
US11034753B2 (en) Regeneration and repair of mesenchymal tissue using amelogenin
AU2012216342A1 (en) Use of neuropeptide Y (NPY) and agonists and antagonists thereof for tissue regeneration

Legal Events

Date Code Title Description
ASS Change of ownership

Owner name: FORMYCON GMBH, DE

Free format text: OLD OWNER(S): SCIL TECHNOLOGY GMBH

S883 Correction of error according to section 88(3) (mistake in register caused on part of patentee or applicant)

Free format text: CORRECTION TO TITLE (54)

PSEA Patent sealed
ASS Change of ownership

Owner name: FORMYCON AG, DE

Free format text: OLD OWNER(S): FORMYCON GMBH

RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 3 YEARS UNTIL 12 SEP 2015 BY AJ PARK

Effective date: 20130424

LAPS Patent lapsed