ZA201001644B - Use of slit,nephrin,ephrin or semaphorin for treatment of cartilage diseases - Google Patents
Use of slit,nephrin,ephrin or semaphorin for treatment of cartilage diseasesInfo
- Publication number
- ZA201001644B ZA201001644B ZA2010/01644A ZA201001644A ZA201001644B ZA 201001644 B ZA201001644 B ZA 201001644B ZA 2010/01644 A ZA2010/01644 A ZA 2010/01644A ZA 201001644 A ZA201001644 A ZA 201001644A ZA 201001644 B ZA201001644 B ZA 201001644B
- Authority
- ZA
- South Africa
- Prior art keywords
- nephrin
- semaphorin
- ephrin
- slit
- treatment
- Prior art date
Links
- VYLJAYXZTOTZRR-BTPDVQIOSA-N CC(C)(O)[C@H]1CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2CC[C@@H]2[C@@]3(C)CCCC(C)(C)[C@@H]3[C@@H](O)[C@H](O)[C@@]12C Chemical compound CC(C)(O)[C@H]1CC[C@@]2(C)[C@H]1CC[C@]1(C)[C@@H]2CC[C@@H]2[C@@]3(C)CCCC(C)(C)[C@@H]3[C@@H](O)[C@H](O)[C@@]12C VYLJAYXZTOTZRR-BTPDVQIOSA-N 0.000 title 1
- 102100023195 Nephrin Human genes 0.000 title 1
- 102000014105 Semaphorin Human genes 0.000 title 1
- 108050003978 Semaphorin Proteins 0.000 title 1
- 208000015100 cartilage disease Diseases 0.000 title 1
- 108060002566 ephrin Proteins 0.000 title 1
- 102000012803 ephrin Human genes 0.000 title 1
- VYLJAYXZTOTZRR-UHFFFAOYSA-N hopane-6alpha,7beta,22-triol Natural products C12CCC3C4(C)CCCC(C)(C)C4C(O)C(O)C3(C)C1(C)CCC1C2(C)CCC1C(C)(O)C VYLJAYXZTOTZRR-UHFFFAOYSA-N 0.000 title 1
- 108010027531 nephrin Proteins 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Psychiatry (AREA)
- Dispersion Chemistry (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07018131A EP2036921A1 (en) | 2007-09-14 | 2007-09-14 | Use of Slit, nephrin, ephrin or semaphorin for treatment of cartilage diseases |
| EP08006810 | 2008-04-03 | ||
| PCT/EP2008/007579 WO2009033715A2 (en) | 2007-09-14 | 2008-09-12 | Neuroendocrine factors for treatment of degenerative diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA201001644B true ZA201001644B (en) | 2011-03-30 |
Family
ID=40452588
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA2010/01644A ZA201001644B (en) | 2007-09-14 | 2010-03-08 | Use of slit,nephrin,ephrin or semaphorin for treatment of cartilage diseases |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20110002972A1 (enExample) |
| EP (1) | EP2212344B1 (enExample) |
| JP (1) | JP2010539123A (enExample) |
| KR (1) | KR20100075493A (enExample) |
| CN (1) | CN101821283A (enExample) |
| AU (1) | AU2008297889A1 (enExample) |
| BR (1) | BRPI0816784A8 (enExample) |
| CA (1) | CA2699411A1 (enExample) |
| MX (1) | MX2010002716A (enExample) |
| NZ (1) | NZ583851A (enExample) |
| RU (1) | RU2496790C2 (enExample) |
| WO (1) | WO2009033715A2 (enExample) |
| ZA (1) | ZA201001644B (enExample) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1400024B1 (it) * | 2010-05-21 | 2013-05-17 | Uni Politecnica Delle Marche | Uso farmaceutico di semaforine. |
| AR084541A1 (es) * | 2010-12-23 | 2013-05-22 | Sanofi Sa | PROTEINA DE FUSION ROBO1-Fc PARA SU USO EN EL TRATAMIENTO DEL HEPATOCARCINOMA |
| EP3653218B1 (en) * | 2011-07-04 | 2024-12-18 | Mesoblast, Inc. | Treating or preventing rheumatic disease |
| WO2013187730A1 (ko) * | 2012-06-15 | 2013-12-19 | 재단법인 아산사회복지재단 | Ｓｌｉｔ-Ｒｏｂｏ 시스템을 이용한 골절 또는 골다공증의 예방 또는 치료용 조성물 |
| ES2442242B1 (es) * | 2012-08-09 | 2014-11-25 | Biotechnology Institute, I Mas D, S.L. | Composición con factores de crecimiento destinada al tratamiento intranasal de una enfermedad neurodegenerativa u otra patología del sistema nervioso central, y su método de fabricación. |
| CN104119445A (zh) * | 2013-04-26 | 2014-10-29 | 李华顺 | 含有富含亮氨酸重复序列的融合蛋白及其制法和应用 |
| CN104119446A (zh) * | 2013-04-26 | 2014-10-29 | 李华顺 | 含有富含亮氨酸重复序列的融合蛋白及其制法和应用 |
| CN104119447A (zh) * | 2013-04-26 | 2014-10-29 | 李华顺 | 含有富含亮氨酸重复序列的融合蛋白及其制法和应用 |
| CN104119448A (zh) * | 2013-04-26 | 2014-10-29 | 李华顺 | 含有富含亮氨酸重复序列的融合蛋白及其制法和应用 |
| JPWO2015072527A1 (ja) * | 2013-11-13 | 2017-03-16 | 国立大学法人大阪大学 | ネトリン１含有破骨細胞形成抑制剤 |
| PL3116521T3 (pl) | 2014-03-14 | 2024-12-16 | The Research Foundation For The State University Of New York | Neurogeniczna regulacja wzrostu i degradacji kości |
| US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
| US20200397860A1 (en) * | 2018-02-14 | 2020-12-24 | Cornell University | Slit and bone growth modulation |
| BR112021016948A2 (pt) * | 2019-02-27 | 2021-11-03 | Daewoong Pharmaceutical Co Ltd | Composição que compreende lrrd2 ligado à albumina de proteína slit3 para prevenção ou tratamento de doenças relacionadas a ossos e uso de lrrd2 ligado à albumina da proteína slit3 |
| KR20220079857A (ko) * | 2019-09-13 | 2022-06-14 | 루트거스, 더 스테이트 유니버시티 오브 뉴 저지 | Aav-상용성 라미닌-링커 중합 단백질 |
| CN110841057B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 一种神经导向因子Sema在制备治疗骨关节炎巴布膏剂中的应用 |
| CN110772632B (zh) * | 2019-11-19 | 2023-08-11 | 四川大学华西医院 | 神经导向因子semaphorin 3a在制备治疗骨关节炎药物中的用途 |
| CN110711244B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 一种神经导向因子Sema在制备治疗骨关节炎搽剂中的应用 |
| CN110684805B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 神经导向因子Sema基因重组慢病毒载体在制备治疗骨关节炎药物中的应用 |
| CN110721308B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 一种用于治疗骨关节炎的药物复方制剂及其制备方法 |
| CN110694051B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 一种神经导向因子Sema在制备治疗骨关节炎注射剂中的应用 |
| US20240277861A1 (en) * | 2021-07-26 | 2024-08-22 | Purotech Bio, Inc. | Anti-hepatitis b virus agent targeting host factor lipg |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2700117B1 (fr) * | 1993-01-07 | 1995-02-03 | Rhone Poulenc Rorer Sa | Application d'anticonvulsivants dans le traitement de la maladie de Parkinson et des syndromes parkinsoniens. |
| JPH1116490A (ja) * | 1997-06-26 | 1999-01-22 | Kyocera Corp | プラズマディスプレイパネル用隔壁の製造方法及びプラズマディスプレイパネル用基板 |
| US20030032057A1 (en) * | 1997-08-26 | 2003-02-13 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
| US6342370B1 (en) * | 1997-10-31 | 2002-01-29 | Osiris Therapeutics, Inc. | Human slit polypeptide and polynucleotides encoding same |
| JPH11164690A (ja) * | 1997-12-05 | 1999-06-22 | Asahi Chem Ind Co Ltd | 脊椎動物スリット蛋白質 |
| US6924355B2 (en) * | 1998-09-01 | 2005-08-02 | Genentech, Inc. | PRO1343 polypeptides |
| AU3755100A (en) * | 1999-03-17 | 2000-10-04 | Washington University | Vertebrate slit dna sequence, protein and uses thereof |
| AU2001278655A1 (en) * | 2000-07-18 | 2002-01-30 | Compugen Ltd. | Novel nucleic acid and amino acid sequences |
| EP1307557A2 (en) * | 2000-08-02 | 2003-05-07 | The Johns Hopkins University | Endothelial cell expression patterns |
| CA2423519A1 (en) * | 2000-08-10 | 2002-02-14 | Pharmacia Corporation | A new slit-like protein obtained from a cdna library from hs-5 stromal cell line |
| WO2002081745A2 (en) * | 2001-04-05 | 2002-10-17 | Proskelia Pharmaceuticals | Genes involved in osteogenesis, and methods of use |
| US20050014680A1 (en) * | 2003-04-15 | 2005-01-20 | Crabtree Gerald R. | Methods and compositions for enhancing neuron growth and survival |
| US20060025335A1 (en) * | 2004-01-30 | 2006-02-02 | Kinane Thomas B | Netrin compositions and methods of using the same |
| CN101600451A (zh) * | 2006-12-11 | 2009-12-09 | 犹他大学研究基金会 | 用于治疗病理性血管生成和血管通透性的组合物和方法 |
-
2008
- 2008-09-12 US US12/677,830 patent/US20110002972A1/en not_active Abandoned
- 2008-09-12 JP JP2010524408A patent/JP2010539123A/ja active Pending
- 2008-09-12 EP EP08802131.6A patent/EP2212344B1/en active Active
- 2008-09-12 AU AU2008297889A patent/AU2008297889A1/en not_active Abandoned
- 2008-09-12 MX MX2010002716A patent/MX2010002716A/es not_active Application Discontinuation
- 2008-09-12 KR KR1020107007806A patent/KR20100075493A/ko not_active Withdrawn
- 2008-09-12 CN CN200880111279A patent/CN101821283A/zh active Pending
- 2008-09-12 BR BRPI0816784A patent/BRPI0816784A8/pt not_active IP Right Cessation
- 2008-09-12 RU RU2010114713/10A patent/RU2496790C2/ru not_active IP Right Cessation
- 2008-09-12 WO PCT/EP2008/007579 patent/WO2009033715A2/en not_active Ceased
- 2008-09-12 NZ NZ583851A patent/NZ583851A/en not_active IP Right Cessation
- 2008-09-12 CA CA2699411A patent/CA2699411A1/en not_active Abandoned
-
2010
- 2010-03-08 ZA ZA2010/01644A patent/ZA201001644B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0816784A2 (pt) | 2015-03-24 |
| BRPI0816784A8 (pt) | 2016-01-19 |
| WO2009033715A2 (en) | 2009-03-19 |
| AU2008297889A1 (en) | 2009-03-19 |
| MX2010002716A (es) | 2010-07-05 |
| RU2010114713A (ru) | 2011-10-20 |
| RU2496790C2 (ru) | 2013-10-27 |
| EP2212344B1 (en) | 2014-03-26 |
| EP2212344A2 (en) | 2010-08-04 |
| KR20100075493A (ko) | 2010-07-02 |
| WO2009033715A3 (en) | 2010-03-18 |
| US20110002972A1 (en) | 2011-01-06 |
| CN101821283A (zh) | 2010-09-01 |
| JP2010539123A (ja) | 2010-12-16 |
| NZ583851A (en) | 2012-06-29 |
| CA2699411A1 (en) | 2009-03-19 |
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