MX2010002716A - Uso de slit, nefrina, efrina o semaforina para el tratamiento de enfermedades de cartilago. - Google Patents
Uso de slit, nefrina, efrina o semaforina para el tratamiento de enfermedades de cartilago.Info
- Publication number
- MX2010002716A MX2010002716A MX2010002716A MX2010002716A MX2010002716A MX 2010002716 A MX2010002716 A MX 2010002716A MX 2010002716 A MX2010002716 A MX 2010002716A MX 2010002716 A MX2010002716 A MX 2010002716A MX 2010002716 A MX2010002716 A MX 2010002716A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- degenerative diseases
- neuroendocrine factors
- polypeptide
- neuroendocrine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Neurosurgery (AREA)
- Epidemiology (AREA)
- Toxicology (AREA)
- Physical Education & Sports Medicine (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Immunology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Dispersion Chemistry (AREA)
- Dermatology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
La presente invención está relacionada con el uso de un factor repelente y/o polipéptido en la elaboración de una composición farmacéutica para tratar una enfermedad tal como una enfermedad degenerativa, en particular al uso de una proteína SLIT3 o NETRINA1 para la misma. La invención está relacionada además con un fragmento de polipéptido de SLIT3, una composición farmacéutica que comprende el polipéptido y el uso de la misma.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07018131A EP2036921A1 (en) | 2007-09-14 | 2007-09-14 | Use of Slit, nephrin, ephrin or semaphorin for treatment of cartilage diseases |
EP08006810 | 2008-04-03 | ||
PCT/EP2008/007579 WO2009033715A2 (en) | 2007-09-14 | 2008-09-12 | Neuroendocrine factors for treatment of degenerative diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010002716A true MX2010002716A (es) | 2010-07-05 |
Family
ID=40452588
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010002716A MX2010002716A (es) | 2007-09-14 | 2008-09-12 | Uso de slit, nefrina, efrina o semaforina para el tratamiento de enfermedades de cartilago. |
Country Status (13)
Country | Link |
---|---|
US (1) | US20110002972A1 (es) |
EP (1) | EP2212344B1 (es) |
JP (1) | JP2010539123A (es) |
KR (1) | KR20100075493A (es) |
CN (1) | CN101821283A (es) |
AU (1) | AU2008297889A1 (es) |
BR (1) | BRPI0816784A8 (es) |
CA (1) | CA2699411A1 (es) |
MX (1) | MX2010002716A (es) |
NZ (1) | NZ583851A (es) |
RU (1) | RU2496790C2 (es) |
WO (1) | WO2009033715A2 (es) |
ZA (1) | ZA201001644B (es) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1400024B1 (it) * | 2010-05-21 | 2013-05-17 | Uni Politecnica Delle Marche | Uso farmaceutico di semaforine. |
AR084541A1 (es) * | 2010-12-23 | 2013-05-22 | Sanofi Sa | PROTEINA DE FUSION ROBO1-Fc PARA SU USO EN EL TRATAMIENTO DEL HEPATOCARCINOMA |
AU2012278925B2 (en) * | 2011-07-04 | 2016-05-19 | Mesoblast, Inc. | Methods of treating or preventing rheumatic disease |
EP2862580A4 (en) * | 2012-06-15 | 2016-06-01 | Asan Foundation | COMPOSITION FOR THE PREVENTION OR TREATMENT OF CRUISES OR OSTEOPOROSIS BY MEANS OF A SLIT-ROBO-SYSTEM |
ES2442242B1 (es) * | 2012-08-09 | 2014-11-25 | Biotechnology Institute, I Mas D, S.L. | Composición con factores de crecimiento destinada al tratamiento intranasal de una enfermedad neurodegenerativa u otra patología del sistema nervioso central, y su método de fabricación. |
CN104119447A (zh) * | 2013-04-26 | 2014-10-29 | 李华顺 | 含有富含亮氨酸重复序列的融合蛋白及其制法和应用 |
CN104119448A (zh) * | 2013-04-26 | 2014-10-29 | 李华顺 | 含有富含亮氨酸重复序列的融合蛋白及其制法和应用 |
CN104119446A (zh) * | 2013-04-26 | 2014-10-29 | 李华顺 | 含有富含亮氨酸重复序列的融合蛋白及其制法和应用 |
CN104119445A (zh) * | 2013-04-26 | 2014-10-29 | 李华顺 | 含有富含亮氨酸重复序列的融合蛋白及其制法和应用 |
JPWO2015072527A1 (ja) * | 2013-11-13 | 2017-03-16 | 国立大学法人大阪大学 | ネトリン1含有破骨細胞形成抑制剤 |
WO2015138874A1 (en) | 2014-03-14 | 2015-09-17 | The Research Foundation For The State University Of New York | Neurogenic regulation of bone growth and bone degradation |
US11052175B2 (en) | 2015-08-19 | 2021-07-06 | Musculoskeletal Transplant Foundation | Cartilage-derived implants and methods of making and using same |
US20200397860A1 (en) * | 2018-02-14 | 2020-12-24 | Cornell University | Slit and bone growth modulation |
BR112021016948A2 (pt) * | 2019-02-27 | 2021-11-03 | Daewoong Pharmaceutical Co Ltd | Composição que compreende lrrd2 ligado à albumina de proteína slit3 para prevenção ou tratamento de doenças relacionadas a ossos e uso de lrrd2 ligado à albumina da proteína slit3 |
JP2022547305A (ja) * | 2019-09-13 | 2022-11-11 | ラトガース,ザ ステート ユニバーシティ オブ ニュー ジャージー | Aav適合性ラミニン-リンカー重合タンパク質 |
CN110684805B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 神经导向因子Sema基因重组慢病毒载体在制备治疗骨关节炎药物中的应用 |
CN110772632B (zh) * | 2019-11-19 | 2023-08-11 | 四川大学华西医院 | 神经导向因子semaphorin 3a在制备治疗骨关节炎药物中的用途 |
CN110694051B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 一种神经导向因子Sema在制备治疗骨关节炎注射剂中的应用 |
CN110841057B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 一种神经导向因子Sema在制备治疗骨关节炎巴布膏剂中的应用 |
CN110721308B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 一种用于治疗骨关节炎的药物复方制剂及其制备方法 |
CN110711244B (zh) * | 2019-11-19 | 2023-08-01 | 四川大学华西医院 | 一种神经导向因子Sema在制备治疗骨关节炎搽剂中的应用 |
EP4378480A1 (en) * | 2021-07-26 | 2024-06-05 | Purotech Bio, Inc. | Anti-hepatitis b virus agent targeting host factor lipg |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2700117B1 (fr) * | 1993-01-07 | 1995-02-03 | Rhone Poulenc Rorer Sa | Application d'anticonvulsivants dans le traitement de la maladie de Parkinson et des syndromes parkinsoniens. |
JPH1116490A (ja) * | 1997-06-26 | 1999-01-22 | Kyocera Corp | プラズマディスプレイパネル用隔壁の製造方法及びプラズマディスプレイパネル用基板 |
US20030032057A1 (en) * | 1997-08-26 | 2003-02-13 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
WO1999023219A1 (en) * | 1997-10-31 | 1999-05-14 | Osiris Therapeutics, Inc. | Human slit polypeptide and polynucleotides encoding same |
JPH11164690A (ja) * | 1997-12-05 | 1999-06-22 | Asahi Chem Ind Co Ltd | 脊椎動物スリット蛋白質 |
US20030096955A1 (en) * | 1998-09-01 | 2003-05-22 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
WO2000055321A2 (en) * | 1999-03-17 | 2000-09-21 | Washington University | Vertebrate protein slit, dna sequence encoding it and uses thereof |
AU2001278655A1 (en) * | 2000-07-18 | 2002-01-30 | Compugen Ltd. | Novel nucleic acid and amino acid sequences |
WO2002010217A2 (en) * | 2000-08-02 | 2002-02-07 | The Johns Hopkins University | Endothelial cell expression patterns |
CA2423519A1 (en) * | 2000-08-10 | 2002-02-14 | Pharmacia Corporation | A new slit-like protein obtained from a cdna library from hs-5 stromal cell line |
US20040265808A1 (en) * | 2001-04-05 | 2004-12-30 | Teresa Garcia | Genes involved in osteogenesis, and methods of use |
US20050014680A1 (en) * | 2003-04-15 | 2005-01-20 | Crabtree Gerald R. | Methods and compositions for enhancing neuron growth and survival |
WO2005074556A2 (en) * | 2004-01-30 | 2005-08-18 | The General Hospital Corporation | Netrin compositions and methods of use thereof |
CA2672297A1 (en) * | 2006-12-11 | 2008-06-19 | University Of Utah Research Foundation | Compositions and methods for treating pathologic angiogenesis and vascular permeability |
-
2008
- 2008-09-12 US US12/677,830 patent/US20110002972A1/en not_active Abandoned
- 2008-09-12 KR KR1020107007806A patent/KR20100075493A/ko not_active Application Discontinuation
- 2008-09-12 JP JP2010524408A patent/JP2010539123A/ja active Pending
- 2008-09-12 NZ NZ583851A patent/NZ583851A/en not_active IP Right Cessation
- 2008-09-12 BR BRPI0816784A patent/BRPI0816784A8/pt not_active IP Right Cessation
- 2008-09-12 EP EP08802131.6A patent/EP2212344B1/en active Active
- 2008-09-12 RU RU2010114713/10A patent/RU2496790C2/ru not_active IP Right Cessation
- 2008-09-12 AU AU2008297889A patent/AU2008297889A1/en not_active Abandoned
- 2008-09-12 CA CA2699411A patent/CA2699411A1/en not_active Abandoned
- 2008-09-12 CN CN200880111279A patent/CN101821283A/zh active Pending
- 2008-09-12 MX MX2010002716A patent/MX2010002716A/es not_active Application Discontinuation
- 2008-09-12 WO PCT/EP2008/007579 patent/WO2009033715A2/en active Application Filing
-
2010
- 2010-03-08 ZA ZA2010/01644A patent/ZA201001644B/en unknown
Also Published As
Publication number | Publication date |
---|---|
JP2010539123A (ja) | 2010-12-16 |
CN101821283A (zh) | 2010-09-01 |
US20110002972A1 (en) | 2011-01-06 |
AU2008297889A1 (en) | 2009-03-19 |
CA2699411A1 (en) | 2009-03-19 |
NZ583851A (en) | 2012-06-29 |
WO2009033715A2 (en) | 2009-03-19 |
ZA201001644B (en) | 2011-03-30 |
EP2212344A2 (en) | 2010-08-04 |
EP2212344B1 (en) | 2014-03-26 |
RU2010114713A (ru) | 2011-10-20 |
BRPI0816784A8 (pt) | 2016-01-19 |
RU2496790C2 (ru) | 2013-10-27 |
WO2009033715A3 (en) | 2010-03-18 |
KR20100075493A (ko) | 2010-07-02 |
BRPI0816784A2 (pt) | 2015-03-24 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
MX2010002716A (es) | Uso de slit, nefrina, efrina o semaforina para el tratamiento de enfermedades de cartilago. | |
WO2009086539A3 (en) | Treatment and prophylaxis of amyloidosis | |
MX358013B (es) | Materiales y metodos para el tratamiento o prevencion de enfermedades asociadas al her-3. | |
JO2576B1 (en) | Antibodies | |
EA201070636A1 (ru) | Ингибирование рецептора белка, стимулирующего макрофаги (ron), и способы его лечения | |
MX2010008206A (es) | Metodos y composiciones que utilizan polipeptidos de fusion de klotho-fgf. | |
TW200744642A (en) | Novel peptides for use in the treatment of obesity | |
MX2008009886A (es) | Anticuerpos que enlazan par-2. | |
CR20110470A (es) | Proteínas de union a il-17 | |
EA201071126A1 (ru) | Антагонисты рецепторов глюкагона | |
AR113422A2 (es) | Agentes tensioactivos reconstituidos que tienen propiedades mejoradas | |
CL2008000021A1 (es) | Compuestos derivados de 2,4-dianilinopirimidinas, inhibidores de proteinas cinasas; procedimiento de preparacion; composicion farmaceutica; y uso para el tratamiento o prevencion de enfermedades inflamatorias, diabetes y cancer. | |
UA96279C2 (ru) | Изолированное антитело или его фрагмент, способное к связыванию с человеческим nogo | |
MX2009006327A (es) | Compuestos heterociclicos y metodos de uso de los mismos. | |
TN2009000194A1 (en) | Novel antiproliferation antibodies | |
ATE464045T1 (de) | Zusammensetzung aus milchsäure und lactoferrin | |
WO2009010968A3 (en) | Disease treatment via antimicrobial peptides or their inhibitors | |
MX2009003039A (es) | Utilizacion de un anticuerpo anti-cd151 para el tratamiento del cancer. | |
WO2008103378A3 (en) | Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist | |
WO2009047513A3 (en) | Antagonists of kisspeptin and uses thereof | |
ATE443722T1 (de) | Peptide und peptidderivate, ihre herstellung sowie ihre verwendung zur herstellung einer therapeutisch und/oder prophylaktisch wirksamen pharmazeutischen zusammensetzung | |
MX337358B (es) | Conjugados de disorazoles y sus derivados con moleculas de union con celulas, nuevos derivados de disorazol, procesos de fabricacion y usos de los mismos. | |
WO2009138494A3 (en) | Amino acid sequences directed against toll-like receptors and their use for the treatment of diseases related to toll-like receptors | |
CL2008001719A1 (es) | Compuestos derivados de [1,10]-fenantrolina; procedimiento de preparacion; composicion farmaceutica; y uso en el tratamiento de enfermedades neurodegenerativas o hematologicas. | |
DE602004029016D1 (de) | Stq-peptide |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB | Transfer or rights |
Owner name: FORMYCON GMBH |
|
FA | Abandonment or withdrawal |