NZ538703A - Modified saccharides, having a linker moiety and a masked aldehyde group, to prevent and treat diseases caused by capsulate bacteria - Google Patents
Modified saccharides, having a linker moiety and a masked aldehyde group, to prevent and treat diseases caused by capsulate bacteriaInfo
- Publication number
- NZ538703A NZ538703A NZ538703A NZ53870303A NZ538703A NZ 538703 A NZ538703 A NZ 538703A NZ 538703 A NZ538703 A NZ 538703A NZ 53870303 A NZ53870303 A NZ 53870303A NZ 538703 A NZ538703 A NZ 538703A
- Authority
- NZ
- New Zealand
- Prior art keywords
- saccharide
- formula
- modified
- group
- alkyl
- Prior art date
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
- C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
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- Epidemiology (AREA)
- Virology (AREA)
- Neurosurgery (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Saccharide Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0220198.6A GB0220198D0 (en) | 2002-08-30 | 2002-08-30 | Modified saccharides,conjugates thereof and their manufacture |
| PCT/IB2003/004194 WO2004019992A1 (en) | 2002-08-30 | 2003-09-01 | Modified saccharides, conjugates thereof, and their manufacture |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ538703A true NZ538703A (en) | 2006-09-29 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ538703A NZ538703A (en) | 2002-08-30 | 2003-09-01 | Modified saccharides, having a linker moiety and a masked aldehyde group, to prevent and treat diseases caused by capsulate bacteria |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8895516B2 (enExample) |
| EP (1) | EP1534342B1 (enExample) |
| JP (2) | JP5268222B2 (enExample) |
| CN (2) | CN101863998B (enExample) |
| AT (1) | ATE319481T1 (enExample) |
| AU (1) | AU2003260921B2 (enExample) |
| BR (1) | BR0314089A (enExample) |
| CA (1) | CA2497167C (enExample) |
| DE (1) | DE60303961T2 (enExample) |
| DK (1) | DK1534342T3 (enExample) |
| ES (1) | ES2260682T3 (enExample) |
| GB (1) | GB0220198D0 (enExample) |
| MX (1) | MXPA05002315A (enExample) |
| NZ (1) | NZ538703A (enExample) |
| RU (2) | RU2005108992A (enExample) |
| WO (1) | WO2004019992A1 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| GB0220198D0 (en) * | 2002-08-30 | 2002-10-09 | Chiron Spa | Modified saccharides,conjugates thereof and their manufacture |
| JP4827726B2 (ja) | 2003-01-30 | 2011-11-30 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | 複数の髄膜炎菌血清群に対する注射可能ワクチン |
| WO2005051429A2 (en) * | 2003-11-19 | 2005-06-09 | Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Targeted conjugates with a modified saccharide linker |
| AU2006245440B2 (en) * | 2005-05-06 | 2012-04-19 | Novartis Vaccines And Diagnostics Srl | Immunogens for meningitidis-A vaccines |
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| US5952454A (en) * | 1997-12-12 | 1999-09-14 | The United States Of America As Represented By The Department Of Health And Human Services | Linking compounds useful for coupling carbohydrates to amine-containing carriers |
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| GB0220198D0 (en) * | 2002-08-30 | 2002-10-09 | Chiron Spa | Modified saccharides,conjugates thereof and their manufacture |
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2002
- 2002-08-30 GB GBGB0220198.6A patent/GB0220198D0/en not_active Ceased
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2003
- 2003-09-01 CA CA2497167A patent/CA2497167C/en not_active Expired - Fee Related
- 2003-09-01 AU AU2003260921A patent/AU2003260921B2/en not_active Ceased
- 2003-09-01 BR BR0314089-0A patent/BR0314089A/pt not_active Application Discontinuation
- 2003-09-01 NZ NZ538703A patent/NZ538703A/en not_active IP Right Cessation
- 2003-09-01 RU RU2005108992/04A patent/RU2005108992A/ru unknown
- 2003-09-01 AT AT03791149T patent/ATE319481T1/de active
- 2003-09-01 DK DK03791149T patent/DK1534342T3/da active
- 2003-09-01 JP JP2004532625A patent/JP5268222B2/ja not_active Expired - Fee Related
- 2003-09-01 CN CN2010101825535A patent/CN101863998B/zh not_active Expired - Fee Related
- 2003-09-01 DE DE60303961T patent/DE60303961T2/de not_active Expired - Lifetime
- 2003-09-01 MX MXPA05002315A patent/MXPA05002315A/es active IP Right Grant
- 2003-09-01 US US10/526,124 patent/US8895516B2/en not_active Expired - Fee Related
- 2003-09-01 WO PCT/IB2003/004194 patent/WO2004019992A1/en not_active Ceased
- 2003-09-01 EP EP03791149A patent/EP1534342B1/en not_active Expired - Lifetime
- 2003-09-01 ES ES03791149T patent/ES2260682T3/es not_active Expired - Lifetime
- 2003-09-01 CN CN038237245A patent/CN1688343B/zh not_active Expired - Fee Related
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|---|---|
| AU2003260921A1 (en) | 2004-03-19 |
| US20060263390A1 (en) | 2006-11-23 |
| EP1534342A1 (en) | 2005-06-01 |
| CA2497167A1 (en) | 2004-03-11 |
| RU2008150551A (ru) | 2010-06-27 |
| BR0314089A (pt) | 2005-11-16 |
| JP2006511465A (ja) | 2006-04-06 |
| DE60303961T2 (de) | 2006-10-26 |
| DK1534342T3 (da) | 2006-07-10 |
| DE60303961D1 (de) | 2006-05-04 |
| MXPA05002315A (es) | 2005-06-08 |
| AU2003260921B2 (en) | 2008-03-06 |
| US8895516B2 (en) | 2014-11-25 |
| RU2531909C2 (ru) | 2014-10-27 |
| CN101863998B (zh) | 2012-08-29 |
| ATE319481T1 (de) | 2006-03-15 |
| CA2497167C (en) | 2011-07-12 |
| US20150166593A1 (en) | 2015-06-18 |
| JP2012017342A (ja) | 2012-01-26 |
| WO2004019992A1 (en) | 2004-03-11 |
| ES2260682T3 (es) | 2006-11-01 |
| GB0220198D0 (en) | 2002-10-09 |
| JP5314745B2 (ja) | 2013-10-16 |
| EP1534342B1 (en) | 2006-03-08 |
| RU2005108992A (ru) | 2005-11-10 |
| CN1688343B (zh) | 2010-09-08 |
| CN1688343A (zh) | 2005-10-26 |
| JP5268222B2 (ja) | 2013-08-21 |
| CN101863998A (zh) | 2010-10-20 |
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