NZ523884A - Process for isolating PUFAs from microbial cells - Google Patents

Process for isolating PUFAs from microbial cells

Info

Publication number
NZ523884A
NZ523884A NZ523884A NZ52388401A NZ523884A NZ 523884 A NZ523884 A NZ 523884A NZ 523884 A NZ523884 A NZ 523884A NZ 52388401 A NZ52388401 A NZ 52388401A NZ 523884 A NZ523884 A NZ 523884A
Authority
NZ
New Zealand
Prior art keywords
oil
process according
pufa
microbial
cells
Prior art date
Application number
NZ523884A
Other languages
English (en)
Inventor
Hendrik Louis Bijl
Albert Schaap
Original Assignee
Dsm N
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8173160&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ523884(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dsm N filed Critical Dsm N
Publication of NZ523884A publication Critical patent/NZ523884A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6463—Glycerides obtained from glyceride producing microorganisms, e.g. single cell oil
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS OR COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings or cooking oils
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/02—Pretreatment
    • C11B1/025—Pretreatment by enzymes or microorganisms, living or dead
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B1/00—Production of fats or fatty oils from raw materials
    • C11B1/06—Production of fats or fatty oils from raw materials by pressing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Fats And Perfumes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
NZ523884A 2000-08-02 2001-08-01 Process for isolating PUFAs from microbial cells NZ523884A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00306601A EP1178118A1 (en) 2000-08-02 2000-08-02 Isolation of microbial oils
PCT/EP2001/008903 WO2002010423A2 (en) 2000-08-02 2001-08-01 Isolation of microbial oils

Publications (1)

Publication Number Publication Date
NZ523884A true NZ523884A (en) 2004-09-24

Family

ID=8173160

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ523884A NZ523884A (en) 2000-08-02 2001-08-01 Process for isolating PUFAs from microbial cells

Country Status (19)

Country Link
US (1) US7431952B2 (https=)
EP (2) EP1178118A1 (https=)
JP (4) JP2004504849A (https=)
KR (6) KR20110030661A (https=)
CN (1) CN1282745C (https=)
AT (1) ATE470719T1 (https=)
AU (2) AU2001293711B2 (https=)
BR (1) BR0112942A (https=)
CA (2) CA2742152C (https=)
DE (1) DE60142339D1 (https=)
DK (1) DK1305440T3 (https=)
EA (1) EA006979B1 (https=)
ES (1) ES2357614T3 (https=)
IL (2) IL154146A0 (https=)
MX (1) MXPA03000878A (https=)
NO (1) NO20030510L (https=)
NZ (1) NZ523884A (https=)
WO (1) WO2002010423A2 (https=)
ZA (1) ZA200300787B (https=)

Families Citing this family (112)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2397655C (en) * 2000-01-19 2012-06-05 Craig M. Ruecker Solventless extraction process
ES2324640T3 (es) * 2001-03-09 2009-08-12 Societe Des Produits Nestle S.A. Aceite que contiene un o unos acido(s) graso(s) poliin-saturado(s) de cadena larga resultante de una biomasa, procedimiento de preparacion, alimento, composicion nutricional, cosmetica o farmaceutica que lo contiene.
US9101151B2 (en) 2002-05-03 2015-08-11 Dsm Ip Assets B.V. High-quality lipids produced by enzymatic liberation from biomass
EP2255667A1 (en) 2002-06-19 2010-12-01 DSM IP Assets B.V. Pasteurisation process for microbial cells and microbial oil
ES2312513T3 (es) * 2002-09-04 2009-03-01 Nestec S.A. Procedimiento para la preparacion de un aceite conteniendo uno o unos acidos grasos poliinsaturados de cadena larga proviniendo de biomasa, alimento, composicion nutricional, cosmetica o farmaceutica conteniendo dicho aceite.
US7601858B2 (en) 2004-08-17 2009-10-13 Gs Cleantech Corporation Method of processing ethanol byproducts and related subsystems
WO2006046943A2 (en) * 2004-10-22 2006-05-04 Martek Biosciences Corporation Methods for producing lipids by liberation from biomass
DE102005003624A1 (de) * 2005-01-26 2006-07-27 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Herstellung und Anwendung eines antioxidativ wirksamen Extraktes aus Crypthecodinium sp.
US9108140B2 (en) 2005-03-16 2015-08-18 Gs Cleantech Corporation Method and systems for washing ethanol production byproducts to improve oil recovery
AU2006325040B2 (en) 2005-06-07 2012-04-19 Dsm Nutritional Products Ag Eukaryotic microorganisms for producing lipids and antioxidants
EA200800225A1 (ru) * 2005-07-01 2008-06-30 Мартек Байосайенсиз Корпорейшн Содержащий полиненасыщенные жирные кислоты маслопродукт и его применения и получение
US8003369B2 (en) * 2005-11-29 2011-08-23 Sanyo Chemical Industries, Ltd. Bacteriolytic agent
CA2659603C (en) 2006-08-01 2017-03-07 Ocean Nutrition Canada Limited Oil producing microbes and methods of modification thereof
US8404004B2 (en) 2006-12-29 2013-03-26 Genifuel Corporation Process of producing oil from algae using biological rupturing
US20090004715A1 (en) 2007-06-01 2009-01-01 Solazyme, Inc. Glycerol Feedstock Utilization for Oil-Based Fuel Manufacturing
US8343753B2 (en) * 2007-11-01 2013-01-01 Wake Forest University School Of Medicine Compositions, methods, and kits for polyunsaturated fatty acids from microalgae
US8043496B1 (en) 2008-03-18 2011-10-25 Peter Allen Schuh System for extracting oil from algae
EP2145942A1 (de) * 2008-07-15 2010-01-20 Lonza Ltd. Verfahren zur Isolierung von Ölen aus Zellen und Biomasse
DK3196313T3 (da) * 2008-10-02 2021-04-06 Ramon Nieves Gonzalez Mikroalgeekstrakt indeholdende polyumættede omega3-fedtsyrer og fremgangsmåde til ekstrahering af olie fra mikroorganismer
US20100303989A1 (en) 2008-10-14 2010-12-02 Solazyme, Inc. Microalgal Flour
US20160324167A1 (en) 2008-10-14 2016-11-10 Terravia Holdings, Inc. Novel microalgal food compositions
MY182693A (en) 2008-11-28 2021-01-29 Terravia Holdings Inc Production of tailored oils in heterotrophic microorganisms
US8207363B2 (en) 2009-03-19 2012-06-26 Martek Biosciences Corporation Thraustochytrids, fatty acid compositions, and methods of making and uses thereof
CN101817738B (zh) * 2009-11-13 2013-08-14 厦门汇盛生物有限公司 一种从藻类和真菌细胞中破壁提取dha的方法
US9924733B2 (en) 2010-01-19 2018-03-27 Dsm Ip Assets B.V. Eicosapentaenoic acid-producing microorganisms, fatty acid compositions, and methods of making and uses thereof
US8187861B1 (en) 2010-01-26 2012-05-29 Allen John Schuh Phosphate removal-recovery and biofuel feedstock system
CN101805670A (zh) * 2010-04-09 2010-08-18 上海中器环保科技有限公司 一种微生物柴油的制备方法
SG10201504187YA (en) 2010-05-28 2015-06-29 Solazyme Inc Tailored oils produced from recombinant heterotrophic microorganisms
EP2576801B1 (en) 2010-06-01 2019-10-02 DSM IP Assets B.V. Extraction of lipid from cells and products therefrom
NL2004832C2 (en) * 2010-06-07 2011-12-08 Evodos B V Separating biomass from an aqueous medium.
US9028696B2 (en) 2010-07-26 2015-05-12 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds from biomass
MX2013000892A (es) 2010-07-26 2013-04-03 Sapphire Energy Inc Proceso para la recuperacion de compuestos oleaginosos a partir de biomasa.
US8906236B2 (en) 2010-07-26 2014-12-09 Sapphire Energy, Inc. Process for the recovery of oleaginous compounds and nutrients from biomass
WO2012038332A1 (en) 2010-09-21 2012-03-29 Shell Internationale Research Maatschappij B.V. Process for separation of a mixture containing a microbial oil and a microbial substance
US9085745B2 (en) * 2010-10-18 2015-07-21 Originoil, Inc. Systems and methods for extracting non-polar lipids from an aqueous algae slurry and lipids produced therefrom
CN108823254A (zh) 2010-11-03 2018-11-16 柯碧恩生物技术公司 具有降低倾点的微生物油、从其中产生的介电流体、以及相关方法
US20120329138A1 (en) 2010-12-23 2012-12-27 Shell Oil Company Process for separation of a mixture containing a microbial substance and a liquid
MX344012B (es) 2011-02-02 2016-12-02 Terravia Holdings Inc Aceites adaptados producidos a partir de microorganismos oleaginosos recombinantes.
WO2012109545A2 (en) * 2011-02-11 2012-08-16 E. I. Du Pont De Nemours And Company Method for obtaining a lipid-containing composition from microbial biomass
AU2012214264A1 (en) * 2011-02-11 2013-07-18 E. I. Du Pont De Nemours And Company Method for forming and extracting solid pellets comprising oil-containing microbes
US8846352B2 (en) 2011-05-06 2014-09-30 Solazyme, Inc. Genetically engineered microorganisms that metabolize xylose
FR2975705B1 (fr) 2011-05-27 2014-12-26 Roquette Freres Procede d'extraction du squalene a partir de microalgues
AU2012285806B2 (en) 2011-07-21 2017-09-14 Dsm Ip Assets B.V. Fatty acid compositions
US8986977B2 (en) * 2011-12-30 2015-03-24 Alliance For Sustainable Energy, Llc Disruption of cell walls for enhanced lipid recovery
SG11201402650RA (en) 2012-01-16 2014-06-27 Elizabeth Mckenna Compositions and methods for the treatment of hepatic diseases and disorders
US12268718B2 (en) * 2012-01-16 2025-04-08 Labyrinth Holdings Llc Control of cellular redox levels
JP6222963B2 (ja) 2012-04-10 2017-11-01 花王株式会社 脂肪酸エステルの製造方法
KR20150001830A (ko) 2012-04-18 2015-01-06 솔라짐, 인코포레이티드 맞춤 오일
KR101432277B1 (ko) * 2012-05-22 2014-08-21 한국과학기술원 양이온성 고분자를 이용한 미세조류로부터 지질의 추출방법 및 추출된 지질을 이용한 바이오디젤 제조방법
CN102702777B (zh) * 2012-06-07 2014-03-19 北京林业大学 一种酶法水解从植物原料中提取水溶性类胡萝卜素的方法
WO2014041985A1 (ja) * 2012-09-11 2014-03-20 Dic株式会社 液晶表示装置
BR112015006264A2 (pt) 2012-09-21 2017-07-04 Mckenna Elizabeth composições de oligonucleotídeos cpg ocorrendo naturalmente e suas aplicações terapêuticas
EP2935544B1 (en) * 2012-12-19 2017-11-08 Buckman Laboratories International, Inc Methods and systems for bio-oil recovery and separation aids therefor
US10098371B2 (en) 2013-01-28 2018-10-16 Solazyme Roquette Nutritionals, LLC Microalgal flour
EP2762008A1 (de) * 2013-02-05 2014-08-06 Evonik Industries AG Verbesserung der Bioverfügbarkeit von Wertstoffen aus Mikroorganismen durch Verwendung eines Rotor-Stator Systems für den Zellaufschluss
EP2970926B1 (en) 2013-03-13 2018-01-31 DSM Nutritional Products AG Engineering microorganisms
KR102023756B1 (ko) * 2013-05-14 2019-09-23 에스케이이노베이션 주식회사 신규 트라우스토키트리드〔Ｔｈｒａｕｓｔｏｃｈｙｔｒｉｄ〕 계 미세조류 트라우스토키트리움〔Ｔｈｒａｕｓｔｏｃｈｙｔｒｉｕｍ〕ｓｐ．ＬＡ６〔ＫＣＴＣ１２３８９ＢＰ〕및 이를 이용한 바이오오일의 생산방법
CN104293475B (zh) * 2013-07-19 2017-07-25 中国石油化工股份有限公司 一种从产油微生物中提取油脂的方法
FR3009619B1 (fr) 2013-08-07 2017-12-29 Roquette Freres Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee
SG11201602638SA (en) 2013-10-04 2016-05-30 Solazyme Inc Tailored oils
PL3077489T3 (pl) 2013-12-04 2021-11-08 Nippon Suisan Kaisha, Ltd. Olej drobnoustrojowy zawierający kwas dihomo-gamma-linolenowy i biomasa drobnoustrojowa zawierająca kwas dihomo-gamma-linolenowy
FI3626806T3 (fi) * 2013-12-20 2024-08-22 Mara Renewables Corp Menetelmiä öljyn talteenottamiseksi mikro-organismeista
PL3083546T3 (pl) * 2013-12-20 2022-05-16 Dsm Ip Assets B.V. Sposoby wytwarzania oleju mikrobiologicznego z komórek mikrobiologicznych
NZ721413A (en) * 2013-12-20 2022-05-27 Dsm Ip Assets Bv Processes for obtaining microbial oil from microbial cells
CN105829539B (zh) 2013-12-20 2023-11-10 帝斯曼营养品股份公司 从微生物中回收油的方法
AU2014369040B2 (en) * 2013-12-20 2019-12-05 Dsm Ip Assets B.V. Processes for obtaining microbial oil from microbial cells
CN105939710B (zh) 2013-12-20 2020-05-08 帝斯曼知识产权资产管理有限公司 用于从微生物细胞获得微生物油的方法
AR098895A1 (es) * 2013-12-20 2016-06-22 Dsm Ip Assets Bv Proceso para obtener aceite microbiano a partir de células microbianas
KR20160101990A (ko) * 2013-12-20 2016-08-26 디에스엠 아이피 어셋츠 비.브이. 바이오연료의 생산에 사용하기 위한 지질 추출 방법
CN103789083B (zh) * 2014-02-17 2016-01-20 南京工业大学大丰海洋产业研究院 一种真菌油脂提取方法
CN106574255A (zh) 2014-07-10 2017-04-19 泰拉瑞亚控股公司 酮脂酰acp合酶基因及其用途
CN104356097B (zh) * 2014-10-20 2016-06-29 中国科学院广州能源研究所 一种微生物油脂基环氧化物的制备方法
CN104513704B (zh) * 2014-12-11 2018-01-12 湖北福星生物科技有限公司 一种无腥味dha油脂的提取方法
CN104479862A (zh) * 2014-12-31 2015-04-01 嘉必优生物工程（武汉）有限公司 一种提取微生物油脂的方法
AR104042A1 (es) 2015-03-26 2017-06-21 Mara Renewables Corp Producción de alta densidad de biomasa y aceite utilizando glicerol en bruto
EP3303552A4 (en) 2015-05-29 2019-01-16 Cargill, Incorporated FERMENTATION METHOD FOR THE PRODUCTION OF STEVIOL GLYCOSIDES WITH MULTIPHASE SUPPLY
EP3303553B1 (en) 2015-05-29 2022-07-27 Cargill, Incorporated Fermentation methods for producing steviol glycosides using high ph
US10612065B2 (en) 2015-05-29 2020-04-07 Cargill, Incorporated Heat treatment to produce glycosides
EP3322796A4 (en) 2015-07-13 2019-03-27 Mara Renewables Corporation IMPROVEMENT OF MICROGENONAL FLUID CHANGES OF XYLOSE
US10844414B2 (en) 2015-08-06 2020-11-24 Cargill, Incorporated Methods for producing steviol glycosides in engineered yeast
US10377792B2 (en) 2016-03-16 2019-08-13 The Texas A&M University System Moisture displacement and simultaneous migration of surface-functionalized algae from water to an extraction solvent using ionic polyelectrolytes
US10851395B2 (en) 2016-06-10 2020-12-01 MARA Renewables Corporation Method of making lipids with improved cold flow properties
US11419350B2 (en) 2016-07-01 2022-08-23 Corbion Biotech, Inc. Feed ingredients comprising lysed microbial cells
JP6998935B2 (ja) * 2016-07-13 2022-01-18 エボニック オペレーションズ ゲーエムベーハー 溶解された脂質含有バイオマスから脂質を分離する方法
WO2018122057A1 (en) * 2016-12-27 2018-07-05 Evonik Degussa Gmbh Method of isolating lipids from a lipids containing biomass
RU2744913C2 (ru) * 2016-12-27 2021-03-17 Эвоник Оперейшенс ГмбХ Способ выделения липидов из липидсодержащей биомассы
CN108570484A (zh) * 2017-03-07 2018-09-25 武汉普赛特膜技术循环利用有限公司 一种使用三次发酵法由藻发酵液中纯化富集dha油脂的方法
US10787625B2 (en) * 2017-07-12 2020-09-29 Bunge Global Innovation Llc Process for extraction of oil from algal biomass
RU2769461C2 (ru) * 2017-08-10 2022-03-31 ДСМ АйПи АССЕТС Б.В. Способ двойного центрифугирования для очистки питательного масла
US11814665B2 (en) 2017-08-17 2023-11-14 Evonik Operations Gmbh Enhanced production of lipids by limitation of at least two limiting nutrient sources
EP3470502A1 (en) 2017-10-13 2019-04-17 Evonik Degussa GmbH Method of separating lipids from a lysed lipids containing biomass
EA202090440A1 (ru) 2017-09-21 2020-07-17 Эвоник Оперейшенс ГмбХ Улучшенное получение липидов путем ограничения по меньшей мере двух источников лимитирующих питательных веществ
CN107904016B (zh) * 2017-11-10 2021-04-20 海南华研胶原科技股份有限公司 一种红藻精油及其制备方法
EP3527664A1 (en) 2018-02-15 2019-08-21 Evonik Degussa GmbH Method of isolating lipids from a lipids containing biomass
WO2019122030A1 (en) * 2017-12-22 2019-06-27 Dsm Ip Assets B.V. Method of separating lipids from a lysed lipids containing biomass
DE202018000893U1 (de) * 2018-02-19 2019-05-22 Dorothea Jürgens Vorrichtung zur umwelt-und energieschonenden Veraschung von Leichen und Leichenteilen unter vorheriger Separierung der flüssigen Anteile und Verwendung der brennbaren Fraktion zur energetischen Weiterverwendung in und auch ausserhalb der Vorrichtung
DK3536800T3 (da) 2018-03-09 2021-11-01 Univ Muenchen Tech Ekstrahering af fornyelige triglycerider fra olieholdige mikroorganismer
BR112020019920A2 (pt) * 2018-03-30 2021-01-05 Dsm Ip Assets B.V. Método de redução de emulsão por lavagem de caldo
EP3794097B1 (en) 2018-05-15 2024-10-23 Evonik Operations GmbH Method of isolating lipids from a lipids containing biomass with aid of hydrophobic silica
WO2019219396A1 (en) 2018-05-15 2019-11-21 Evonik Operations Gmbh Method of isolating lipids from a lysed lipids containing biomass by emulsion inversion
CN108753457A (zh) * 2018-08-03 2018-11-06 梁云 提高微生物油脂稳定性和安全性的方法
CN108753458A (zh) * 2018-08-03 2018-11-06 梁云 提高微生物油脂稳定性和安全性的精炼工艺
FR3085825B1 (fr) 2018-09-14 2021-07-16 Fermentalg Huile de microorganismes riche en acide docosahexaenoique
CN113574045A (zh) * 2019-03-14 2021-10-29 帝斯曼知识产权资产管理有限公司 从微生物细胞组合物中获得脂质的方法
CN111363614A (zh) * 2019-10-10 2020-07-03 润科生物工程（福建）有限公司 一种非溶剂式提取花生四烯酸油脂的方法
CN110760369A (zh) * 2019-11-08 2020-02-07 润科生物工程（福建）有限公司 一种纯物理提取花生四烯酸油脂的方法
MX2022012322A (es) 2020-04-03 2022-11-10 Mara Renewables Corp Aceites microbianos con niveles altos de ácidos grasos omega-3.
CN111518611A (zh) * 2020-04-28 2020-08-11 上海容邦企业集团有限公司 沙棘果油复合物及制备方法
CN113684087B (zh) * 2020-05-18 2024-04-19 嘉必优生物技术（武汉）股份有限公司 一种微生物油脂无溶剂提取方法及所得微生物油脂
EP3933016A1 (en) * 2020-06-30 2022-01-05 Evonik Operations GmbH Method of isolating lipids from a lipids containing biomass
FR3111912B1 (fr) 2020-06-24 2025-10-03 Fermentalg Procédé de culture de microorganismes pour l’accumulation de lipides
KR102795205B1 (ko) * 2022-01-27 2025-04-10 씨제이제일제당 (주) 냉각 공정을 이용한 오일 회수율이 향상된 바이오오일 추출 방법

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB808128A (en) * 1955-12-01 1959-01-28 Nat Res Dev A method of increasing the fatty contents of such micro-organisms as yeasts, bacteria and moulds
DE3248167A1 (de) * 1982-12-27 1984-06-28 Wintershall Ag, 3100 Celle Trehaloselipidtetraester
JPS61170397A (ja) * 1985-01-22 1986-08-01 Agency Of Ind Science & Technol モルテイエレラ属糸状菌体の多段抽出処理方法
JPS62278987A (ja) * 1986-05-26 1987-12-03 Kanegafuchi Chem Ind Co Ltd 酵素反応生成物の回収方法
DK199887D0 (da) * 1987-04-15 1987-04-15 Danisco Bioteknologi As Gaerstamme
JPS63304990A (ja) * 1987-06-04 1988-12-13 Meiji Seika Kaisha Ltd 菌体内有効成分の抽出方法
JPH0198494A (ja) * 1987-10-09 1989-04-17 Agency Of Ind Science & Technol バイオリアクター
KR900004067A (ko) * 1988-08-02 1990-03-27 김용원 100v/220v 겸용 코넥터, 콘센트 및 전압선택 플러그
US5130242A (en) * 1988-09-07 1992-07-14 Phycotech, Inc. Process for the heterotrophic production of microbial products with high concentrations of omega-3 highly unsaturated fatty acids
FR2656874B1 (fr) * 1990-01-11 1992-04-03 Commissariat Energie Atomique Procede de production et d'extraction d'anti-oxydants a partir d'une culture de micro-organismes et photobioreacteur pour la mise en óoeuvre de ce procede.
US5658767A (en) * 1991-01-24 1997-08-19 Martek Corporation Arachidonic acid and methods for the production and use thereof
FR2686619B1 (fr) * 1992-01-28 1995-07-13 Commissariat Energie Atomique Procede de production selective de lipides poly-insatures a partir d'une culture de micro-algues du type porphyridium et cuve utilisee dans ce procede.
DE4219360C2 (de) * 1992-06-12 1994-07-28 Milupa Ag Verfahren zur Gewinnung von Lipiden mit einem hohen Anteil von langkettig-hochungesättigten Fettsäuren
EP0776356B1 (de) * 1994-08-16 1999-06-30 Dr. Frische GmbH Verfahren zur gewinnung von nicht wasserlöslichen, nativen produkten aus nativen stoffgemengen mit hilfe der zentrifugalkraft
KR100212644B1 (ko) * 1994-10-29 1999-08-02 토니헬샴 유압식 건설기계의 엔진회전수 제어장치 및 제어방법
US5583019A (en) * 1995-01-24 1996-12-10 Omegatech Inc. Method for production of arachidonic acid
ATE178087T1 (de) * 1995-05-04 1999-04-15 Nestle Sa Verfahren zur fraktionierung von fettsäuren
JPH099981A (ja) * 1995-06-28 1997-01-14 Sekiyu Sangyo Kasseika Center 油水二相系微生物反応における油水分離方法
GB9514649D0 (en) * 1995-07-18 1995-09-13 Zeneca Ltd Extraction of triglycerides from microorganisms
CN1217029A (zh) * 1996-03-28 1999-05-19 吉斯特-布罗卡迪斯股份有限公司 从用巴氏法灭菌的生物量中制备含有微生物多不饱和脂肪酸的油的方法
JP4545235B2 (ja) * 1996-03-28 2010-09-15 ディーエスエム アイピー アセッツ ビー．ブイ． 顆粒状微生物バイオマスの製造法とそのバイオマスからの貴重化合物の単離法
US6509178B1 (en) 1996-07-23 2003-01-21 Suntory Ltd. Process for preparing docosahexaenoic acid and docosapentaenoic acid with ulkenia
JP4346692B2 (ja) 1997-05-02 2009-10-21 コニンクリーケ デーエスエム ナムローゼ フェンノートシャップ 微生物バイオマスからのカロテノイド結晶の単離
JP3836231B2 (ja) * 1997-10-17 2006-10-25 日本化学飼料株式会社 ホタテガイ中腸腺から得られる高度不飽和脂肪酸含有油及びその製造方法
AU2015099A (en) * 1997-12-23 1999-07-12 Dcv, Inc. Doing Business As Bio-Technical Resources Linoleate isomerase
JP2000041684A (ja) * 1998-07-29 2000-02-15 Daicel Chem Ind Ltd 新規なｄ−アミノアシラーゼおよびその製造方法、並びに該ｄ−アミノアシラーゼを利用したｄ−アミノ酸の製造方法
JP2000135096A (ja) * 1998-08-28 2000-05-16 Tadayuki Imanaka 界面活性剤、その生産方法およびその利用方法
CA2397655C (en) * 2000-01-19 2012-06-05 Craig M. Ruecker Solventless extraction process

Also Published As

Publication number Publication date
US7431952B2 (en) 2008-10-07
AU9371101A (en) 2002-02-13
JP2014138598A (ja) 2014-07-31
ATE470719T1 (de) 2010-06-15
NO20030510D0 (no) 2003-01-31
EP1305440B2 (en) 2022-03-30
NO20030510L (no) 2003-03-31
JP2016208974A (ja) 2016-12-15
CA2742152A1 (en) 2002-02-07
IL154146A (en) 2015-06-30
CN1447860A (zh) 2003-10-08
WO2002010423A8 (en) 2004-05-13
JP2012019794A (ja) 2012-02-02
EP1178118A1 (en) 2002-02-06
MXPA03000878A (es) 2003-06-06
KR20130109249A (ko) 2013-10-07
CA2417571C (en) 2011-09-27
EA200300212A1 (ru) 2003-06-26
EA006979B1 (ru) 2006-06-30
CN1282745C (zh) 2006-11-01
IL154146A0 (en) 2003-07-31
KR20110030661A (ko) 2011-03-23
EP1305440B1 (en) 2010-06-09
US20040067574A1 (en) 2004-04-08
KR20100019579A (ko) 2010-02-18
WO2002010423A3 (en) 2002-10-03
ZA200300787B (en) 2004-02-19
AU2001293711B2 (en) 2006-08-24
ES2357614T3 (es) 2011-04-28
EP1305440A2 (en) 2003-05-02
BR0112942A (pt) 2003-07-08
KR101515317B1 (ko) 2015-04-24
KR101447912B1 (ko) 2014-11-11
KR20030059086A (ko) 2003-07-07
DK1305440T3 (da) 2010-09-13
CA2417571A1 (en) 2002-02-07
KR101648277B1 (ko) 2016-08-12
DE60142339D1 (de) 2010-07-22
KR20120135322A (ko) 2012-12-12
KR20140087054A (ko) 2014-07-08
JP2004504849A (ja) 2004-02-19
CA2742152C (en) 2016-04-19
WO2002010423A2 (en) 2002-02-07

Similar Documents

Publication Publication Date Title
CA2742152C (en) Isolation of microbial oils
AU2001293711A1 (en) Isolation of microbial oils
US9408404B2 (en) Method for producing lipids by liberation from biomass
AU2014203384B2 (en) Solventless extraction process
WO2006046943A2 (en) Methods for producing lipids by liberation from biomass
HK1152490A (en) High quality lipids and methods for producing by enzymatic liberation from biomass
HK1154906B (en) Solventless extraction process

Legal Events

Date Code Title Description
PSEA Patent sealed
RENW Renewal (renewal fees accepted)
ASS Change of ownership

Owner name: DSM IP ASSETS B.V., NL

Free format text: OLD OWNER(S): DSM IP ASSETS B.V.; DSM N.V.

RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)
RENW Renewal (renewal fees accepted)

Free format text: PATENT RENEWED FOR 7 YEARS UNTIL 01 AUG 2021 BY CPA GLOBAL

Effective date: 20140620

EXPY Patent expired