NZ518057A - A substrate and a method for determining and/or monitoring electrophysiological properties of ion channels - Google Patents
A substrate and a method for determining and/or monitoring electrophysiological properties of ion channelsInfo
- Publication number
- NZ518057A NZ518057A NZ518057A NZ51805700A NZ518057A NZ 518057 A NZ518057 A NZ 518057A NZ 518057 A NZ518057 A NZ 518057A NZ 51805700 A NZ51805700 A NZ 51805700A NZ 518057 A NZ518057 A NZ 518057A
- Authority
- NZ
- New Zealand
- Prior art keywords
- substrate
- ion channel
- surface part
- electrodes
- containing structure
- Prior art date
Links
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- 238000000034 method Methods 0.000 title claims abstract description 54
- 238000012544 monitoring process Methods 0.000 title claims abstract description 16
- 102000004310 Ion Channels Human genes 0.000 title claims description 125
- 150000002500 ions Chemical class 0.000 claims abstract description 26
- 229910052709 silver Inorganic materials 0.000 claims abstract description 12
- 239000004332 silver Substances 0.000 claims abstract description 12
- 238000012545 processing Methods 0.000 claims abstract description 8
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- 239000007788 liquid Substances 0.000 claims description 43
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- XUIMIQQOPSSXEZ-UHFFFAOYSA-N Silicon Chemical compound [Si] XUIMIQQOPSSXEZ-UHFFFAOYSA-N 0.000 claims description 18
- 229910052710 silicon Inorganic materials 0.000 claims description 18
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means
- G01N33/48728—Investigating individual cells, e.g. by patch clamp, voltage clamp
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analyzing Materials By The Use Of Electric Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA199901407 | 1999-10-01 | ||
| PCT/DK2000/000548 WO2001025769A2 (en) | 1999-10-01 | 2000-10-02 | A substrate and a method for determining and/or monitoring electrophysiological properties of ion channels |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ518057A true NZ518057A (en) | 2004-01-30 |
Family
ID=8104506
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ518057A NZ518057A (en) | 1999-10-01 | 2000-10-02 | A substrate and a method for determining and/or monitoring electrophysiological properties of ion channels |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP1221046B1 (enExample) |
| JP (1) | JP4861584B2 (enExample) |
| CN (1) | CN1204404C (enExample) |
| AT (1) | ATE317545T1 (enExample) |
| AU (1) | AU780157B2 (enExample) |
| CA (1) | CA2385482C (enExample) |
| DE (1) | DE60025929T2 (enExample) |
| DK (1) | DK1221046T3 (enExample) |
| IL (1) | IL148650A0 (enExample) |
| NZ (1) | NZ518057A (enExample) |
| WO (1) | WO2001025769A2 (enExample) |
Families Citing this family (91)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20020144905A1 (en) | 1997-12-17 | 2002-10-10 | Christian Schmidt | Sample positioning and analysis system |
| US7244349B2 (en) | 1997-12-17 | 2007-07-17 | Molecular Devices Corporation | Multiaperture sample positioning and analysis system |
| DE19948473A1 (de) | 1999-10-08 | 2001-04-12 | Nmi Univ Tuebingen | Verfahren und Vorrichtung zum Messen an in einer flüssigen Umgebung befindlichen Zellen |
| FR2802078B1 (fr) * | 1999-12-14 | 2003-10-03 | Univ Joseph Fourier | Microelectrode support de cellules a membrane excitable |
| CA2413663A1 (en) * | 2000-07-07 | 2002-01-17 | Charles D. Weaver | Electrophysiology configuration suitable for high throughput screening of compounds for drug discovery |
| US7270730B2 (en) | 2000-08-04 | 2007-09-18 | Essen Instruments, Inc. | High-throughput electrophysiological measurement system |
| US7067046B2 (en) | 2000-08-04 | 2006-06-27 | Essen Instruments, Inc. | System for rapid chemical activation in high-throughput electrophysiological measurements |
| WO2002024862A2 (en) * | 2000-09-19 | 2002-03-28 | Cytion S.A. | Sample positioning and analysis system |
| US6932893B2 (en) | 2000-10-02 | 2005-08-23 | Sophion Bioscience A/S | System for electrophysiological measurements |
| AU2001293676B2 (en) * | 2000-10-02 | 2006-07-27 | Sophion Bioscience A/S | System for electrophysiological measurements |
| US6776896B1 (en) | 2000-10-11 | 2004-08-17 | Axon Instruments, Inc. | Method of positioning cells for electrophysiological testing |
| EP1352952A1 (en) * | 2001-01-09 | 2003-10-15 | Matsushita Electric Industrial Co., Ltd. | Device for measuring extracellular potential, method of measuring extracellular potential by using the same and apparatus for quickly screening drug provided therewith |
| CA2441366A1 (en) | 2001-03-24 | 2002-10-03 | Aviva Biosciences Corporation | Biochips including ion transport detecting structures and methods of use |
| US20060029955A1 (en) | 2001-03-24 | 2006-02-09 | Antonio Guia | High-density ion transport measurement biochip devices and methods |
| US6899800B2 (en) | 2001-06-20 | 2005-05-31 | Axon Instruments, Inc. | Polymeric electrode for electrophysiological testing |
| CN1529814A (zh) * | 2001-06-20 | 2004-09-15 | 索菲昂生物科学有限公司 | 一种用于确定和/或监控离子通道电生理学性质的装置和方法 |
| JP2003043009A (ja) | 2001-07-30 | 2003-02-13 | Matsushita Electric Ind Co Ltd | 生体試料の発する物理化学的変化を検出するデバイスおよび装置 |
| DE10142393C1 (de) * | 2001-08-30 | 2003-01-23 | Fraunhofer Ges Forschung | Vorrichtung und Verfahren zur Erfassung bioelektrischer Signale aus elektrophysiologisch aktiven Bereichen in Sphäroiden |
| DE10202887B4 (de) * | 2002-01-25 | 2004-05-06 | Advalytix Ag | Zellanalyseverfahren |
| JP2005517180A (ja) * | 2002-02-05 | 2005-06-09 | ザ ユニヴァーシティー コート オブ ザ ユニヴァーシティー オブ グラスゴー | 細胞検定を実施するための装置 |
| WO2003068906A1 (en) | 2002-02-12 | 2003-08-21 | Cellectricon Ab | Systems and methods for rapidly changing the solution environment around sensors |
| US7470518B2 (en) | 2002-02-12 | 2008-12-30 | Cellectricon Ab | Systems and method for rapidly changing the solution environment around sensors |
| GB0207845D0 (en) * | 2002-04-04 | 2002-05-15 | Lgc Ltd | Apparatus, methods and means for biochemical analysis |
| GB2398635A (en) * | 2003-02-21 | 2004-08-25 | Sophion Bioscience As | A substrate providing a cell gigaseal for a patch clamp |
| EP1495105B1 (en) * | 2002-04-17 | 2007-02-21 | Sophion Bioscience A/S | Substrate and method for measuring the electrophysiological properties of cell membranes |
| AU2003231300A1 (en) * | 2002-05-04 | 2003-11-17 | Aviva Biosciences Corporation | Apparatus including ion transport detecting structures and methods of use |
| CN100370247C (zh) * | 2002-05-13 | 2008-02-20 | 松下电器产业株式会社 | 生物样本的活动信号测量装置和测量方法 |
| ES2208082B1 (es) * | 2002-05-29 | 2005-09-16 | Jose Luis Bardasano Rubio | Dispositivo para la medida del potencial de la accion transmembrana en preparaciones celulares bajo la accion de campos electromagneticos de frecuencia e intensidad variables. |
| US8202439B2 (en) | 2002-06-05 | 2012-06-19 | Panasonic Corporation | Diaphragm and device for measuring cellular potential using the same, manufacturing method of the diaphragm |
| JP4552423B2 (ja) * | 2003-11-21 | 2010-09-29 | パナソニック株式会社 | 細胞外電位測定デバイスおよびこれを用いた細胞外電位の測定方法 |
| JP3861831B2 (ja) * | 2003-03-07 | 2006-12-27 | 松下電器産業株式会社 | 細胞外電位測定デバイスおよびその製造方法 |
| JP3945317B2 (ja) * | 2002-06-05 | 2007-07-18 | 松下電器産業株式会社 | 細胞外電位測定デバイスおよびその製造方法 |
| WO2004079354A1 (ja) * | 2003-03-07 | 2004-09-16 | Matsushita Electric Industrial Co., Ltd. | 細胞外電位測定デバイスおよびその製造方法 |
| EP1411351A4 (en) | 2002-06-05 | 2010-07-07 | Panasonic Corp | DEVICE FOR MEASURING THE EXTRACELLULAR POTENTIAL AND METHOD FOR PRODUCING THE DEVICE |
| JP3925439B2 (ja) * | 2003-03-07 | 2007-06-06 | 松下電器産業株式会社 | 細胞外電位測定デバイスおよびその製造方法 |
| JP3945338B2 (ja) * | 2002-08-01 | 2007-07-18 | 松下電器産業株式会社 | 細胞外電位測定デバイスおよびその製造方法 |
| WO2006022092A1 (ja) | 2004-08-25 | 2006-03-02 | Matsushita Electric Industrial Co., Ltd. | 細胞電位測定プローブ |
| WO2003104455A1 (en) * | 2002-06-07 | 2003-12-18 | Sophion Bioscience A/S | Screening methods |
| US7470533B2 (en) | 2002-12-20 | 2008-12-30 | Acea Biosciences | Impedance based devices and methods for use in assays |
| US7468255B2 (en) | 2002-12-20 | 2008-12-23 | Acea Biosciences | Method for assaying for natural killer, cytotoxic T-lymphocyte and neutrophil-mediated killing of target cells using real-time microelectronic cell sensing technology |
| AU2003269911A1 (en) | 2002-07-20 | 2004-02-09 | Acea Biosciences, Inc. | Impedance based apparatuses and methods for analyzing cells and particles |
| US8206903B2 (en) | 2002-12-20 | 2012-06-26 | Acea Biosciences | Device and method for electroporation-based delivery of molecules into cells and dynamic monitoring of cell responses |
| US8263375B2 (en) | 2002-12-20 | 2012-09-11 | Acea Biosciences | Dynamic monitoring of activation of G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK) in living cells using real-time microelectronic cell sensing technology |
| US7732127B2 (en) | 2002-12-20 | 2010-06-08 | Acea Biosciences, Inc. | Dynamic monitoring of cell adhesion and spreading using the RT-CES system |
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2000
- 2000-10-02 DK DK00962271T patent/DK1221046T3/da active
- 2000-10-02 WO PCT/DK2000/000548 patent/WO2001025769A2/en not_active Ceased
- 2000-10-02 NZ NZ518057A patent/NZ518057A/en not_active IP Right Cessation
- 2000-10-02 AT AT00962271T patent/ATE317545T1/de not_active IP Right Cessation
- 2000-10-02 CA CA2385482A patent/CA2385482C/en not_active Expired - Fee Related
- 2000-10-02 CN CNB008136157A patent/CN1204404C/zh not_active Expired - Fee Related
- 2000-10-02 IL IL14865000A patent/IL148650A0/xx unknown
- 2000-10-02 AU AU74065/00A patent/AU780157B2/en not_active Ceased
- 2000-10-02 JP JP2001528683A patent/JP4861584B2/ja not_active Expired - Lifetime
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Also Published As
| Publication number | Publication date |
|---|---|
| EP1221046A2 (en) | 2002-07-10 |
| CA2385482C (en) | 2011-01-18 |
| CN1204404C (zh) | 2005-06-01 |
| IL148650A0 (en) | 2002-09-12 |
| DE60025929T2 (de) | 2006-11-09 |
| WO2001025769A2 (en) | 2001-04-12 |
| CN1377464A (zh) | 2002-10-30 |
| JP2003511668A (ja) | 2003-03-25 |
| AU780157B2 (en) | 2005-03-03 |
| ATE317545T1 (de) | 2006-02-15 |
| AU7406500A (en) | 2001-05-10 |
| WO2001025769A3 (en) | 2001-08-30 |
| DK1221046T3 (da) | 2006-06-12 |
| JP4861584B2 (ja) | 2012-01-25 |
| CA2385482A1 (en) | 2001-04-12 |
| EP1221046B1 (en) | 2006-02-08 |
| DE60025929D1 (de) | 2006-04-20 |
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