|
US20020144905A1
(en)
|
1997-12-17 |
2002-10-10 |
Christian Schmidt |
Sample positioning and analysis system
|
|
US7244349B2
(en)
|
1997-12-17 |
2007-07-17 |
Molecular Devices Corporation |
Multiaperture sample positioning and analysis system
|
|
DE19948473A1
(de)
*
|
1999-10-08 |
2001-04-12 |
Nmi Univ Tuebingen |
Verfahren und Vorrichtung zum Messen an in einer flüssigen Umgebung befindlichen Zellen
|
|
FR2802078B1
(fr)
*
|
1999-12-14 |
2003-10-03 |
Univ Joseph Fourier |
Microelectrode support de cellules a membrane excitable
|
|
AU7189801A
(en)
*
|
2000-07-07 |
2002-01-21 |
Bristol Myers Squibb Co |
Electrophysiology configuration suitable for high throughput screening of compounds for drug discovery
|
|
US7067046B2
(en)
|
2000-08-04 |
2006-06-27 |
Essen Instruments, Inc. |
System for rapid chemical activation in high-throughput electrophysiological measurements
|
|
US7270730B2
(en)
|
2000-08-04 |
2007-09-18 |
Essen Instruments, Inc. |
High-throughput electrophysiological measurement system
|
|
WO2002024862A2
(en)
*
|
2000-09-19 |
2002-03-28 |
Cytion S.A. |
Sample positioning and analysis system
|
|
US6932893B2
(en)
|
2000-10-02 |
2005-08-23 |
Sophion Bioscience A/S |
System for electrophysiological measurements
|
|
AU2001293676B2
(en)
*
|
2000-10-02 |
2006-07-27 |
Sophion Bioscience A/S |
System for electrophysiological measurements
|
|
US6776896B1
(en)
|
2000-10-11 |
2004-08-17 |
Axon Instruments, Inc. |
Method of positioning cells for electrophysiological testing
|
|
JPWO2002055653A1
(ja)
*
|
2001-01-09 |
2004-05-20 |
松下電器産業株式会社 |
細胞外電位測定用デバイス、それを用いた細胞外電位測定方法およびそれを備えた高速薬品スクリーニング装置
|
|
US20060029955A1
(en)
|
2001-03-24 |
2006-02-09 |
Antonio Guia |
High-density ion transport measurement biochip devices and methods
|
|
EP1372828A4
(en)
|
2001-03-24 |
2008-10-29 |
Aviva Biosciences Corp |
BIOCHIPS WITH ION TRANSPORTATION STRUCTURES AND USE METHOD
|
|
WO2002103354A1
(en)
*
|
2001-06-20 |
2002-12-27 |
Sophion Bioscience A/S |
An apparatus and method for determining and/or monitoring electrophysiological properties of ion channels
|
|
US6899800B2
(en)
|
2001-06-20 |
2005-05-31 |
Axon Instruments, Inc. |
Polymeric electrode for electrophysiological testing
|
|
JP2003043009A
(ja)
*
|
2001-07-30 |
2003-02-13 |
Matsushita Electric Ind Co Ltd |
生体試料の発する物理化学的変化を検出するデバイスおよび装置
|
|
DE10142393C1
(de)
*
|
2001-08-30 |
2003-01-23 |
Fraunhofer Ges Forschung |
Vorrichtung und Verfahren zur Erfassung bioelektrischer Signale aus elektrophysiologisch aktiven Bereichen in Sphäroiden
|
|
DE10202887B4
(de)
*
|
2002-01-25 |
2004-05-06 |
Advalytix Ag |
Zellanalyseverfahren
|
|
EP1472538A2
(en)
|
2002-02-05 |
2004-11-03 |
The University of Glasgow, University Court |
Device for performing cell assays
|
|
US7470518B2
(en)
|
2002-02-12 |
2008-12-30 |
Cellectricon Ab |
Systems and method for rapidly changing the solution environment around sensors
|
|
JP4511189B2
(ja)
|
2002-02-12 |
2010-07-28 |
セレクトリコン アーベー |
センサーの周囲の溶液環境を迅速に変化させるシステム及び方法
|
|
GB0207845D0
(en)
*
|
2002-04-04 |
2002-05-15 |
Lgc Ltd |
Apparatus, methods and means for biochemical analysis
|
|
AU2003229926A1
(en)
*
|
2002-04-17 |
2003-11-03 |
Sophion Bioscience A/S |
Substrate and method for measuring the electrophysiological properties of cell membranes
|
|
GB2398635A
(en)
*
|
2003-02-21 |
2004-08-25 |
Sophion Bioscience As |
A substrate providing a cell gigaseal for a patch clamp
|
|
CA2485099C
(en)
|
2002-05-04 |
2017-09-26 |
Aviva Biosciences Corporation |
Apparatus including ion transport detecting structures and methods of use
|
|
CN100370247C
(zh)
*
|
2002-05-13 |
2008-02-20 |
松下电器产业株式会社 |
生物样本的活动信号测量装置和测量方法
|
|
ES2208082B1
(es)
*
|
2002-05-29 |
2005-09-16 |
Jose Luis Bardasano Rubio |
Dispositivo para la medida del potencial de la accion transmembrana en preparaciones celulares bajo la accion de campos electromagneticos de frecuencia e intensidad variables.
|
|
JP3925439B2
(ja)
*
|
2003-03-07 |
2007-06-06 |
松下電器産業株式会社 |
細胞外電位測定デバイスおよびその製造方法
|
|
US8257962B2
(en)
|
2003-03-07 |
2012-09-04 |
Panasonic Corporation |
Extracellular potential measuring device and its manufacturing method
|
|
US8202439B2
(en)
|
2002-06-05 |
2012-06-19 |
Panasonic Corporation |
Diaphragm and device for measuring cellular potential using the same, manufacturing method of the diaphragm
|
|
JP4552423B2
(ja)
|
2003-11-21 |
2010-09-29 |
パナソニック株式会社 |
細胞外電位測定デバイスおよびこれを用いた細胞外電位の測定方法
|
|
EP1411351A4
(en)
*
|
2002-06-05 |
2010-07-07 |
Panasonic Corp |
DEVICE FOR MEASURING THE EXTRACELLULAR POTENTIAL AND METHOD FOR PRODUCING THE DEVICE
|
|
WO2009034697A1
(ja)
|
2007-09-11 |
2009-03-19 |
Panasonic Corporation |
シリコン構造体およびその製造方法並びにセンサチップ
|
|
JP3945338B2
(ja)
*
|
2002-08-01 |
2007-07-18 |
松下電器産業株式会社 |
細胞外電位測定デバイスおよびその製造方法
|
|
JP3861831B2
(ja)
*
|
2003-03-07 |
2006-12-27 |
松下電器産業株式会社 |
細胞外電位測定デバイスおよびその製造方法
|
|
JP3945317B2
(ja)
*
|
2002-06-05 |
2007-07-18 |
松下電器産業株式会社 |
細胞外電位測定デバイスおよびその製造方法
|
|
CA2488449A1
(en)
*
|
2002-06-07 |
2003-12-18 |
Sophion Bioscience A/S |
Screening methods
|
|
US8206903B2
(en)
|
2002-12-20 |
2012-06-26 |
Acea Biosciences |
Device and method for electroporation-based delivery of molecules into cells and dynamic monitoring of cell responses
|
|
US7732127B2
(en)
|
2002-12-20 |
2010-06-08 |
Acea Biosciences, Inc. |
Dynamic monitoring of cell adhesion and spreading using the RT-CES system
|
|
US7560269B2
(en)
|
2002-12-20 |
2009-07-14 |
Acea Biosciences, Inc. |
Real time electronic cell sensing system and applications for cytotoxicity profiling and compound assays
|
|
CA2493108C
(en)
|
2002-07-20 |
2011-08-30 |
Xiaobo Wang |
Impedance based devices and methods for use in assays
|
|
US7468255B2
(en)
|
2002-12-20 |
2008-12-23 |
Acea Biosciences |
Method for assaying for natural killer, cytotoxic T-lymphocyte and neutrophil-mediated killing of target cells using real-time microelectronic cell sensing technology
|
|
US7470533B2
(en)
|
2002-12-20 |
2008-12-30 |
Acea Biosciences |
Impedance based devices and methods for use in assays
|
|
US8263375B2
(en)
|
2002-12-20 |
2012-09-11 |
Acea Biosciences |
Dynamic monitoring of activation of G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK) in living cells using real-time microelectronic cell sensing technology
|
|
US7810380B2
(en)
|
2003-03-25 |
2010-10-12 |
Tearlab Research, Inc. |
Systems and methods for collecting tear film and measuring tear film osmolarity
|
|
AU2003269975A1
(en)
*
|
2002-08-21 |
2004-03-11 |
Cellectricon Ab |
System and method for obtaining and maintaining high resistance seals in patch clamp recordings
|
|
EP1801586B1
(en)
*
|
2002-08-21 |
2010-10-13 |
Cellectricon Ab |
System for obtaining and maintaining high-resistance seals in patch clamp recordings
|
|
FR2844052B1
(fr)
|
2002-08-28 |
2005-07-01 |
Commissariat Energie Atomique |
Dispositif de mesure de l'activite electrique d'elements biologiques et ses applications
|
|
US8232074B2
(en)
|
2002-10-16 |
2012-07-31 |
Cellectricon Ab |
Nanoelectrodes and nanotips for recording transmembrane currents in a plurality of cells
|
|
US10551371B2
(en)
|
2003-11-10 |
2020-02-04 |
Acea Biosciences, Inc. |
System and method for monitoring cardiomyocyte beating, viability and morphology and for screening for pharmacological agents which may induce cardiotoxicity or modulate cardiomyocyte function
|
|
US10215748B2
(en)
|
2002-12-20 |
2019-02-26 |
Acea Biosciences, Inc. |
Using impedance-based cell response profiling to identify putative inhibitors for oncogene addicted targets or pathways
|
|
US11346797B2
(en)
|
2002-12-20 |
2022-05-31 |
Agilent Technologies, Inc. |
System and method for monitoring cardiomyocyte beating, viability, morphology and electrophysiological properties
|
|
US10539523B2
(en)
|
2002-12-20 |
2020-01-21 |
Acea Biosciences, Inc. |
System and method for monitoring cardiomyocyte beating, viability, morphology, and electrophysiological properties
|
|
GB0303920D0
(en)
*
|
2003-02-21 |
2003-03-26 |
Sophion Bioscience As |
Capillary stop
|
|
JP4728956B2
(ja)
|
2003-06-10 |
2011-07-20 |
イサム リサーチ デベロップメント カンパニー オブ ザ ヘブルー ユニバーシティ オブ エルサレム |
生体細胞との通信のための電子装置
|
|
EP1692258A4
(en)
|
2003-11-12 |
2007-03-21 |
Xiao Xu |
REAL-TIME ELECTRONIC CELL DETECTION SYSTEMS FOR CELL-BASED TESTS
|
|
CA2556219A1
(en)
*
|
2004-02-09 |
2005-08-25 |
Acea Biosciences, Inc. |
Methods for assaying cells using cell-substrate impedance monitoring
|
|
FR2866958B1
(fr)
|
2004-02-26 |
2006-08-04 |
Commissariat Energie Atomique |
Procede et dispositif de controle du positionnement d'un element biologique sur un support
|
|
WO2006012571A1
(en)
*
|
2004-07-23 |
2006-02-02 |
Electronic Bio Sciences, Llc |
Method and apparatus for sensing a time varying current passing through an ion channel
|
|
US7736477B2
(en)
|
2004-08-25 |
2010-06-15 |
Panasonic Corporation |
Probe for measuring electric potential of cell
|
|
JP2006184207A
(ja)
*
|
2004-12-28 |
2006-07-13 |
Matsushita Electric Ind Co Ltd |
細胞膜の特性および状態の少なくとも一方の電気的測定方法および電気的測定装置
|
|
US20060216203A1
(en)
*
|
2005-03-28 |
2006-09-28 |
Mds Sciex (Us) A Division Of Mds Pharma Services (Us) Inc. |
Multiwell sample plate with integrated impedance electrodes and connection scheme
|
|
EP1767929B1
(en)
|
2005-06-07 |
2014-03-05 |
Panasonic Corporation |
Apparatus for measuring the electrical physiology of cells
|
|
JP4661539B2
(ja)
*
|
2005-11-11 |
2011-03-30 |
パナソニック株式会社 |
細胞電気生理センサおよびその製造方法
|
|
US7608417B2
(en)
*
|
2005-11-14 |
2009-10-27 |
Panasonic Corporation |
Cell electro-physiological sensor and method of manufacturing the same
|
|
JP4470999B2
(ja)
|
2005-12-20 |
2010-06-02 |
パナソニック株式会社 |
細胞電気生理センサ
|
|
JP2009156572A
(ja)
*
|
2006-04-06 |
2009-07-16 |
National Institutes Of Natural Sciences |
イオンチャンネルタンパク質バイオセンサー
|
|
JP4596009B2
(ja)
|
2006-05-25 |
2010-12-08 |
パナソニック株式会社 |
細胞電気生理センサ用チップとこれを用いた細胞電気生理センサおよび細胞電気生理センサ用チップの製造方法
|
|
EP2037258A4
(en)
|
2006-07-06 |
2013-12-04 |
Panasonic Corp |
APPARATUS FOR CELL ELECTROPHYSIOLOGY SENSOR, CELL ELECTROPHYSIOLOGY SENSOR USING THE DEVICE AND METHOD FOR PRODUCING THE CELL ELECTROPHYSIOLOGY SENSOR DEVICE
|
|
US8041515B2
(en)
|
2006-09-20 |
2011-10-18 |
Acea Biosciences, Inc. |
Use of impedance-based cytological profiling to classify cellular response profiles upon exposure to biologically active agents
|
|
US8163527B2
(en)
*
|
2007-05-04 |
2012-04-24 |
Tecella Llc |
Subsystems and methods for use in patch clamp systems
|
|
EP2291645B1
(en)
|
2008-05-05 |
2015-09-09 |
Acea Biosciences, Inc. |
Label-free monitoring of excitation-contraction coupling and excitable cells using impedance based systems with millisecond time resolution
|
|
WO2011146531A1
(en)
|
2010-05-18 |
2011-11-24 |
Acea Biosciences, Inc |
Data analysis of impedance-based cardiomyocyte-beating signals as detected on real-time cell analysis (rtca) cardio instruments
|
|
DK2590743T3
(en)
|
2010-07-09 |
2016-09-12 |
Sophion Bioscience As |
Chip unit for use in a mikrofluidanalysesystem
|
|
JP5575623B2
(ja)
*
|
2010-12-03 |
2014-08-20 |
マルボシ酢株式会社 |
誘電特性測定用耐圧容器センサーに用いる絶縁体
|
|
JP6037717B2
(ja)
*
|
2011-12-20 |
2016-12-07 |
国立研究開発法人科学技術振興機構 |
プレーナーパッチクランプ装置、該装置用電極部及び細胞イオンチャンネル電流計測方法
|
|
EP2802416B1
(en)
|
2012-01-09 |
2016-04-06 |
Sophion Bioscience A/S |
Improved patch area cell adhesion
|
|
DE102013007295B4
(de)
*
|
2013-04-26 |
2015-06-25 |
Universität Rostock |
Elektrophysiologische Messanordnung und elektrophysiologisches Messverfahren
|
|
TW201536915A
(zh)
|
2013-08-30 |
2015-10-01 |
Japan Science & Tech Agency |
平面膜片箝制裝置及平面膜片箝制系統
|
|
AU2015320685B2
(en)
|
2014-09-23 |
2021-01-28 |
Tearlab Research, Inc. |
Systems and methods for integration of microfluidic tear collection and lateral flow analysis of analytes of interest
|
|
US12066428B2
(en)
|
2015-11-20 |
2024-08-20 |
Agilent Technologies, Inc. |
Cell-substrate impedance monitoring of cancer cells
|
|
WO2017175879A1
(ja)
*
|
2016-04-05 |
2017-10-12 |
シャープ株式会社 |
センサ装置、検出方法、及びセンサユニット
|
|
JP6676486B2
(ja)
|
2016-04-05 |
2020-04-08 |
シャープ株式会社 |
検出方法
|
|
US11746328B2
(en)
|
2017-03-03 |
2023-09-05 |
Agilent Technologies, Inc. |
Methods and systems for functional maturation of iPSC and ESC derived cardiomyocytes
|
|
TWI695166B
(zh)
*
|
2017-11-03 |
2020-06-01 |
國立臺灣大學 |
一種多離子感測電極陣列試片及其感測裝置
|
|
JP7229110B2
(ja)
|
2019-06-25 |
2023-02-27 |
株式会社Screenホールディングス |
細胞電位測定装置
|
|
JP7469092B2
(ja)
*
|
2020-03-23 |
2024-04-16 |
株式会社Screenホールディングス |
細胞保持容器
|
|
US20210301245A1
(en)
|
2020-03-29 |
2021-09-30 |
Agilent Technologies, Inc. |
Systems and methods for electronically and optically monitoring biological samples
|
|
EP4460695B1
(en)
|
2022-01-07 |
2025-12-24 |
Sophion Bioscience A/S |
Semi-automated patch-clamp apparatus and a method for carrying out a patch-clamp procedure
|
|
WO2023131694A1
(en)
|
2022-01-07 |
2023-07-13 |
Sophion Bioscience A/S |
Pipette guidance in multiple-well plate patch-clamp
|