NZ242493A - Quinoline derivatives and pharmaceutical compositions - Google Patents

Quinoline derivatives and pharmaceutical compositions

Info

Publication number
NZ242493A
NZ242493A NZ242493A NZ24249392A NZ242493A NZ 242493 A NZ242493 A NZ 242493A NZ 242493 A NZ242493 A NZ 242493A NZ 24249392 A NZ24249392 A NZ 24249392A NZ 242493 A NZ242493 A NZ 242493A
Authority
NZ
New Zealand
Prior art keywords
ureido
bis
chlorophenyl
methylthio
quinoline
Prior art date
Application number
NZ242493A
Other languages
English (en)
Inventor
Ernest S Hamanaka
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NZ242493A publication Critical patent/NZ242493A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
NZ242493A 1991-04-26 1992-04-24 Quinoline derivatives and pharmaceutical compositions NZ242493A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69232391A 1991-04-26 1991-04-26

Publications (1)

Publication Number Publication Date
NZ242493A true NZ242493A (en) 1994-08-26

Family

ID=24780107

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ242493A NZ242493A (en) 1991-04-26 1992-04-24 Quinoline derivatives and pharmaceutical compositions

Country Status (20)

Country Link
EP (1) EP0590094A1 (pt)
JP (1) JPH0776215B2 (pt)
CN (1) CN1066068A (pt)
AU (1) AU1879792A (pt)
BR (1) BR9205939A (pt)
CA (1) CA2108014A1 (pt)
CZ (1) CZ395592A3 (pt)
DE (1) DE9290049U1 (pt)
FI (1) FI934710A0 (pt)
HU (1) HUT65748A (pt)
IE (1) IE921330A1 (pt)
IL (1) IL101627A0 (pt)
MX (1) MX9201916A (pt)
NO (1) NO933837L (pt)
NZ (1) NZ242493A (pt)
PT (1) PT100426A (pt)
TW (1) TW197436B (pt)
WO (1) WO1992019614A1 (pt)
YU (1) YU44592A (pt)
ZA (1) ZA922976B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3323393A (en) * 1992-01-23 1993-09-01 Pfizer Inc. 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
US5565472A (en) * 1992-12-21 1996-10-15 Pfizer Inc. 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
NZ264063A (en) * 1993-08-13 1995-11-27 Nihon Nohyaku Co Ltd N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions
US5843957A (en) * 1995-05-19 1998-12-01 Sumitomo Pharmaceuticals Company, Ltd. Naphthyridine derivatives
NZ308228A (en) * 1995-05-31 1999-11-29 Sumitomo Pharma Substituted 1,8-naphthyridine derivatives
KR20000057268A (ko) * 1996-11-26 2000-09-15 다께우찌 마사야쓰 나프티리딘 유도체
US6452008B2 (en) 1998-02-25 2002-09-17 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for preparing the same
AU2547399A (en) 1998-02-25 1999-09-15 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for producing the same
KR20070001922A (ko) * 2003-12-12 2007-01-04 와이어쓰 심장혈관질환 치료에 유용한 퀴놀린
CN103601677B (zh) * 2013-11-19 2015-11-18 清华大学 制备2-烷硫基喹啉衍生物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
MX22406A (es) * 1989-09-15 1994-01-31 Pfizer Nuevos derivados de n-aril y n-heteroarilamidas y urea como inhibidores de acil coenzima a: acil transferasa del colesterol (acat).
TW205037B (pt) * 1989-10-06 1993-05-01 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
FI934710A (fi) 1993-10-25
CA2108014A1 (en) 1992-10-27
CN1066068A (zh) 1992-11-11
BR9205939A (pt) 1994-09-27
AU1879792A (en) 1992-12-21
WO1992019614A1 (en) 1992-11-12
IE921330A1 (en) 1992-11-04
ZA922976B (en) 1993-10-25
HU9303025D0 (en) 1994-01-28
YU44592A (sh) 1994-12-28
FI934710A0 (fi) 1993-10-25
CZ395592A3 (en) 1994-02-16
EP0590094A1 (en) 1994-04-06
MX9201916A (es) 1992-11-01
IL101627A0 (en) 1992-12-30
HUT65748A (en) 1994-07-28
DE9290049U1 (de) 1994-01-05
PT100426A (pt) 1993-08-31
JPH06501025A (ja) 1994-01-27
JPH0776215B2 (ja) 1995-08-16
TW197436B (pt) 1993-01-01
NO933837L (no) 1993-10-25

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