MX9201916A - Derivados de 4-aril-3-hetero aril ureido quinolina como agentes antihipercolesterolemicos y antiaterosclerosicos. - Google Patents

Derivados de 4-aril-3-hetero aril ureido quinolina como agentes antihipercolesterolemicos y antiaterosclerosicos.

Info

Publication number
MX9201916A
MX9201916A MX9201916A MX9201916A MX9201916A MX 9201916 A MX9201916 A MX 9201916A MX 9201916 A MX9201916 A MX 9201916A MX 9201916 A MX9201916 A MX 9201916A MX 9201916 A MX9201916 A MX 9201916A
Authority
MX
Mexico
Prior art keywords
aryl
atherosclerosic
ureid
hypercholesterolemic
quinoline
Prior art date
Application number
MX9201916A
Other languages
English (en)
Spanish (es)
Inventor
Ernest S Hamanaka
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MX9201916A publication Critical patent/MX9201916A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D215/00Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
MX9201916A 1991-04-26 1992-04-24 Derivados de 4-aril-3-hetero aril ureido quinolina como agentes antihipercolesterolemicos y antiaterosclerosicos. MX9201916A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69232391A 1991-04-26 1991-04-26

Publications (1)

Publication Number Publication Date
MX9201916A true MX9201916A (es) 1992-11-01

Family

ID=24780107

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9201916A MX9201916A (es) 1991-04-26 1992-04-24 Derivados de 4-aril-3-hetero aril ureido quinolina como agentes antihipercolesterolemicos y antiaterosclerosicos.

Country Status (20)

Country Link
EP (1) EP0590094A1 (pt)
JP (1) JPH0776215B2 (pt)
CN (1) CN1066068A (pt)
AU (1) AU1879792A (pt)
BR (1) BR9205939A (pt)
CA (1) CA2108014A1 (pt)
CZ (1) CZ395592A3 (pt)
DE (1) DE9290049U1 (pt)
FI (1) FI934710A (pt)
HU (1) HUT65748A (pt)
IE (1) IE921330A1 (pt)
IL (1) IL101627A0 (pt)
MX (1) MX9201916A (pt)
NO (1) NO933837L (pt)
NZ (1) NZ242493A (pt)
PT (1) PT100426A (pt)
TW (1) TW197436B (pt)
WO (1) WO1992019614A1 (pt)
YU (1) YU44592A (pt)
ZA (1) ZA922976B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993015058A1 (en) * 1992-01-23 1993-08-05 Pfizer Inc. 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
US5565472A (en) * 1992-12-21 1996-10-15 Pfizer Inc. 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
NZ264063A (en) * 1993-08-13 1995-11-27 Nihon Nohyaku Co Ltd N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions
US5843957A (en) * 1995-05-19 1998-12-01 Sumitomo Pharmaceuticals Company, Ltd. Naphthyridine derivatives
KR100399798B1 (ko) * 1995-05-31 2004-05-31 스미또모 세이야꾸 가부시키가이샤 신규나프티리딘유도체
CN1245500A (zh) * 1996-11-26 2000-02-23 住友制药株式会社 新型萘啶衍生物
US6452008B2 (en) 1998-02-25 2002-09-17 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for preparing the same
EP1086948A4 (en) 1998-02-25 2004-03-10 Sumitomo Pharma PYRIDONE DERIVATIVES AND THEIR MANUFACTURING PROCESS
AU2004298486A1 (en) 2003-12-12 2005-06-30 Wyeth Quinolines useful in treating cardiovascular disease
CN103601677B (zh) * 2013-11-19 2015-11-18 清华大学 制备2-烷硫基喹啉衍生物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
WO1991004027A1 (en) * 1989-09-15 1991-04-04 Pfizer Inc. New n-aryl and n-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme a: cholesterol acyl transferase (acat)
TW205037B (pt) * 1989-10-06 1993-05-01 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
WO1992019614A1 (en) 1992-11-12
CZ395592A3 (en) 1994-02-16
AU1879792A (en) 1992-12-21
FI934710A0 (fi) 1993-10-25
DE9290049U1 (de) 1994-01-05
HUT65748A (en) 1994-07-28
NO933837L (no) 1993-10-25
NZ242493A (en) 1994-08-26
BR9205939A (pt) 1994-09-27
IL101627A0 (en) 1992-12-30
PT100426A (pt) 1993-08-31
CA2108014A1 (en) 1992-10-27
CN1066068A (zh) 1992-11-11
JPH0776215B2 (ja) 1995-08-16
EP0590094A1 (en) 1994-04-06
IE921330A1 (en) 1992-11-04
YU44592A (sh) 1994-12-28
HU9303025D0 (en) 1994-01-28
JPH06501025A (ja) 1994-01-27
TW197436B (pt) 1993-01-01
ZA922976B (en) 1993-10-25
FI934710A (fi) 1993-10-25

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees