NZ240247A - Purified monoclonal antibodies against cd 52 lymphocyte antigen - Google Patents

Purified monoclonal antibodies against cd 52 lymphocyte antigen

Info

Publication number
NZ240247A
NZ240247A NZ240247A NZ24024791A NZ240247A NZ 240247 A NZ240247 A NZ 240247A NZ 240247 A NZ240247 A NZ 240247A NZ 24024791 A NZ24024791 A NZ 24024791A NZ 240247 A NZ240247 A NZ 240247A
Authority
NZ
New Zealand
Prior art keywords
antibody
column
purified preparation
protein
cdw52
Prior art date
Application number
NZ240247A
Other languages
English (en)
Inventor
Paul Ian Nicholas Ramage
Geoffrey Allen
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10683866&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ240247(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Priority to NZ244114A priority Critical patent/NZ244114A/en
Publication of NZ240247A publication Critical patent/NZ240247A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065Purification, fragmentation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2893Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD52
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NZ240247A 1990-10-17 1991-10-16 Purified monoclonal antibodies against cd 52 lymphocyte antigen NZ240247A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
NZ244114A NZ244114A (en) 1990-10-17 1991-10-16 Recombinant antibody, process for purifying it, and pharmaceutical compositions

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909022547A GB9022547D0 (en) 1990-10-17 1990-10-17 Purified immunoglobulin

Publications (1)

Publication Number Publication Date
NZ240247A true NZ240247A (en) 1994-03-25

Family

ID=10683866

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ244114A NZ244114A (en) 1990-10-17 1991-10-16 Recombinant antibody, process for purifying it, and pharmaceutical compositions
NZ240247A NZ240247A (en) 1990-10-17 1991-10-16 Purified monoclonal antibodies against cd 52 lymphocyte antigen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NZ244114A NZ244114A (en) 1990-10-17 1991-10-16 Recombinant antibody, process for purifying it, and pharmaceutical compositions

Country Status (29)

Country Link
US (1) US5644036A (OSRAM)
EP (1) EP0504363B2 (OSRAM)
JP (1) JP2638680B2 (OSRAM)
KR (2) KR960015399B1 (OSRAM)
AT (2) ATE162552T1 (OSRAM)
AU (3) AU658926B2 (OSRAM)
BE (1) BE1004226A5 (OSRAM)
BR (1) BR1100358A (OSRAM)
CA (1) CA2069481C (OSRAM)
CH (2) CH681455A5 (OSRAM)
DE (1) DE69128774T3 (OSRAM)
DK (1) DK0504363T4 (OSRAM)
ES (2) ES2081742B1 (OSRAM)
FI (2) FI110003B (OSRAM)
FR (2) FR2668164A1 (OSRAM)
GB (2) GB9022547D0 (OSRAM)
GR (3) GR910100425A (OSRAM)
HU (1) HUT64601A (OSRAM)
IE (1) IE913560A1 (OSRAM)
IL (3) IL99761A0 (OSRAM)
IT (1) IT1250064B (OSRAM)
LU (1) LU88122A1 (OSRAM)
MX (1) MX9203794A (OSRAM)
MY (2) MY136210A (OSRAM)
NZ (2) NZ244114A (OSRAM)
PT (2) PT99248B (OSRAM)
TW (1) TW283710B (OSRAM)
WO (1) WO1992007084A1 (OSRAM)
ZA (2) ZA918259B (OSRAM)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
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GB9022545D0 (en) 1990-10-17 1990-11-28 Wellcome Found Culture medium
JP3535155B2 (ja) * 1991-10-15 2004-06-07 ビー・ティー・ジー・インターナショナル・リミテッド 関節のT細胞介在炎症の治療のためのCDw52特異抗体
GB9125768D0 (en) * 1991-12-04 1992-02-05 Hale Geoffrey Therapeutic method
GB9300501D0 (en) * 1993-01-09 1993-03-03 Wellcome Found Purification of immunoglobulin
US6149917A (en) 1995-08-01 2000-11-21 Pasteur Merieux Serums Et Vaccins Industrial production process for a vaccine against Japanese encephalitis virus and vaccine produced
US6090382A (en) * 1996-02-09 2000-07-18 Basf Aktiengesellschaft Human antibodies that bind human TNFα
DK0929578T3 (da) * 1996-02-09 2003-08-25 Abbott Lab Bermuda Ltd Humane antistoffer, der binder human TNFalfa
GB9603256D0 (en) * 1996-02-16 1996-04-17 Wellcome Found Antibodies
US20030023043A1 (en) * 2000-03-02 2003-01-30 Kazuhisa Uchida Method of separating and purifying protein
EP2336149A1 (en) 2001-03-09 2011-06-22 Chugai Seiyaku Kabushiki Kaisha Protein purification method
NZ530025A (en) * 2001-06-05 2005-06-24 Inst Genetics Llc Methods for purifying highly anionic proteins
GB0220894D0 (en) * 2002-09-09 2002-10-16 Millipore Uk Ltd Method of separation
ES2558303T3 (es) 2002-09-11 2016-02-03 Chugai Seiyaku Kabushiki Kaisha Método de purificación de proteínas
WO2004035618A2 (en) 2002-10-15 2004-04-29 Intercell Ag Nucleic acids coding for adhesion factor of group b streptococcus, adhesion factors of group b streptococcus and further uses thereof
GB0304576D0 (en) * 2003-02-28 2003-04-02 Lonza Biologics Plc Protein a chromatography
US20070286857A1 (en) * 2003-12-22 2007-12-13 Genzyme Corporation Anti-Cd52 Antibody Treatment for Diabetes
ES2797480T3 (es) * 2005-03-11 2020-12-02 Wyeth Llc Un procedimiento de cromatografía de reparto débil
CA2647846C (en) 2006-03-31 2016-06-21 Chugai Seiyaku Kabushiki Kaisha Methods for controlling blood pharmacokinetics of antibodies
CN106519025B (zh) 2007-09-26 2021-04-23 中外制药株式会社 利用cdr的氨基酸取代来改变抗体等电点的方法
CA2721052C (en) 2008-04-11 2023-02-21 Chugai Seiyaku Kabushiki Kaisha Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
CN102438654A (zh) 2009-05-13 2012-05-02 基酶有限公司 治疗狼疮的方法和组合物
NZ621170A (en) 2009-05-13 2015-08-28 Genzyme Corp Anti-human cd52 immunoglobulins
EP2695889A1 (en) * 2009-12-29 2014-02-12 Dr. Reddy's Laboratories Limited Protein purification by ion exchange
WO2011162210A1 (ja) 2010-06-21 2011-12-29 協和発酵キリン株式会社 アミノ酸を利用したタンパク質の精製方法
RU2467783C2 (ru) * 2010-07-30 2012-11-27 Закрытое акционерное общество "БиоХимМак СТ" Способ хроматографического выделения иммуноглобулина
BR112013013354A2 (pt) 2010-11-30 2020-10-06 Chugai Seiyaku Kabushiki Kaisha molécula de ligação ao antígeno capaz de se ligar a uma pluralidade de moléculas de antígeno repetidamente
US9062106B2 (en) 2011-04-27 2015-06-23 Abbvie Inc. Methods for controlling the galactosylation profile of recombinantly-expressed proteins
GB201109238D0 (en) * 2011-06-01 2011-07-13 Antitope Ltd Antibodies
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US9150645B2 (en) 2012-04-20 2015-10-06 Abbvie, Inc. Cell culture methods to reduce acidic species
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
US9249182B2 (en) 2012-05-24 2016-02-02 Abbvie, Inc. Purification of antibodies using hydrophobic interaction chromatography
US9650411B2 (en) 2012-08-07 2017-05-16 Kyowa Hakko Kirin Co., Ltd. Method of purifying protein
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
EP2890782A1 (en) 2012-09-02 2015-07-08 AbbVie Inc. Methods to control protein heterogeneity
HK1207960A1 (en) 2013-03-12 2016-02-19 Abbvie Inc. Human antibodies that bind human tnf-alpha and methods of preparing the same
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2014151878A2 (en) 2013-03-14 2014-09-25 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
WO2014159579A1 (en) 2013-03-14 2014-10-02 Abbvie Inc. MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
AU2013203043B2 (en) 2013-03-15 2016-10-06 Takeda Pharmaceutical Company Limited Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs
AR095199A1 (es) 2013-03-15 2015-09-30 Genzyme Corp Anticuerpos anti-cd52
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
IL296754A (en) 2013-12-27 2022-11-01 Chugai Pharmaceutical Co Ltd A method for isolating an antibody with a low isoelectric point
MY181199A (en) 2014-12-19 2020-12-21 Chugai Pharmaceutical Co Ltd Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use
US10858391B2 (en) 2015-07-31 2020-12-08 Chugai Seiyaku Kabushiki Kaisha Method for purifying composition comprising antibodies with anionic polymer
WO2017110981A1 (en) 2015-12-25 2017-06-29 Chugai Seiyaku Kabushiki Kaisha Anti-myostatin antibodies and methods of use
US10688412B2 (en) 2016-07-25 2020-06-23 Cehpalon, Inc. Affinity chromatography wash buffer
JP6527643B2 (ja) 2016-08-05 2019-06-05 中外製薬株式会社 Il−8関連疾患の治療用又は予防用組成物
EP3950099A4 (en) 2019-03-29 2022-05-18 Asahi Kasei Medical Co., Ltd. Method for purifying protein
US12383884B2 (en) 2019-04-08 2025-08-12 Asahi Kasei Medical Co., Ltd. Polyamide medium for purifying protein-containing solution and method for producing polyamide medium
CA3136398A1 (en) 2019-04-10 2020-10-15 Chugai Seiyaku Kabushiki Kaisha Method for purifying fc region-modified antibody
CN117241881A (zh) 2021-06-10 2023-12-15 三菱化学株式会社 合成吸附剂、抗体的纯化方法和抗体的制造方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5118796A (en) * 1987-12-09 1992-06-02 Centocor, Incorporated Efficient large-scale purification of immunoglobulins and derivatives
DE68909441T2 (de) * 1988-02-12 1994-02-10 British Tech Group Modifizierte Antikörper.

Also Published As

Publication number Publication date
BR1100358A (pt) 2000-03-28
US5644036A (en) 1997-07-01
IL102726A0 (en) 1993-01-31
HU9202000D0 (en) 1992-10-28
FI110002B (fi) 2002-11-15
PT100988A (pt) 1994-02-28
LU88122A1 (fr) 1993-03-15
NZ244114A (en) 1995-06-27
JP2638680B2 (ja) 1997-08-06
ES2112865T3 (es) 1998-04-16
KR100193314B1 (ko) 1999-06-15
KR920703108A (ko) 1992-12-17
ATE162552T1 (de) 1998-02-15
AU2532192A (en) 1993-02-11
GR920100471A (el) 1994-06-30
CH681305A5 (OSRAM) 1993-02-26
MY119030A (en) 2005-03-31
FI922380L (fi) 1992-05-25
FI922824L (fi) 1992-06-17
DE69128774D1 (de) 1998-02-26
DE69128774T3 (de) 2007-08-16
FR2677997A1 (fr) 1992-12-24
DE69128774T2 (de) 1998-06-04
GB2253397A (en) 1992-09-09
GB9022547D0 (en) 1990-11-28
JPH05504579A (ja) 1993-07-15
AU4521897A (en) 1998-02-12
TW283710B (OSRAM) 1996-08-21
AU8729491A (en) 1992-05-20
MX9203794A (es) 1992-07-01
EP0504363B1 (en) 1998-01-21
EP0504363A1 (en) 1992-09-23
ITRM910788A1 (it) 1993-04-16
MY136210A (en) 2008-08-29
FI922824A0 (fi) 1992-06-17
FI110003B (fi) 2002-11-15
ES2112865T5 (es) 2007-09-16
ATA900791A (de) 1996-06-15
BE1004226A5 (fr) 1992-10-13
WO1992007084A1 (en) 1992-04-30
ES2081742B1 (es) 1996-10-01
PT99248A (pt) 1993-06-30
IL102726A (en) 2002-08-14
DK0504363T3 (da) 1998-09-21
ZA918259B (en) 1993-04-16
GB9209529D0 (en) 1992-07-01
PT100988B (pt) 1999-08-31
CA2069481A1 (en) 1992-04-18
IE913560A1 (en) 1992-04-22
FR2668164A1 (fr) 1992-04-24
CA2069481C (en) 2003-07-29
AU7024294A (en) 1995-01-05
ITRM910788A0 (it) 1991-10-16
GR910100425A (el) 1992-09-25
FI922380A0 (fi) 1992-05-25
EP0504363B2 (en) 2007-02-07
CH681455A5 (OSRAM) 1993-03-31
ES2081742A1 (es) 1996-03-01
GR3026588T3 (en) 1998-07-31
AU716402B2 (en) 2000-02-24
IT1250064B (it) 1995-03-30
IL99761A0 (en) 1992-08-18
AU658926B2 (en) 1995-05-04
ZA926191B (en) 1993-04-16
FR2668164B1 (OSRAM) 1995-04-14
KR960015399B1 (ko) 1996-11-13
DK0504363T4 (da) 2007-05-29
PT99248B (pt) 1999-04-30
HUT64601A (en) 1994-01-28
AU649078B2 (en) 1994-05-12

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