NZ202708A - N-(vinblastinoyl-23)derivatives of amino acids,their preparation and pharmaceutical compositions - Google Patents

N-(vinblastinoyl-23)derivatives of amino acids,their preparation and pharmaceutical compositions

Info

Publication number
NZ202708A
NZ202708A NZ202708A NZ20270882A NZ202708A NZ 202708 A NZ202708 A NZ 202708A NZ 202708 A NZ202708 A NZ 202708A NZ 20270882 A NZ20270882 A NZ 20270882A NZ 202708 A NZ202708 A NZ 202708A
Authority
NZ
New Zealand
Prior art keywords
group
ethyl
alkyl
oyl
deacetyl
Prior art date
Application number
NZ202708A
Other languages
English (en)
Inventor
A B L Trouet
K S B Rao
J A A Hannart
Original Assignee
Omnichem Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Omnichem Sa filed Critical Omnichem Sa
Publication of NZ202708A publication Critical patent/NZ202708A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NZ202708A 1981-12-08 1982-12-03 N-(vinblastinoyl-23)derivatives of amino acids,their preparation and pharmaceutical compositions NZ202708A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
LU83822A LU83822A1 (fr) 1981-12-08 1981-12-08 Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique

Publications (1)

Publication Number Publication Date
NZ202708A true NZ202708A (en) 1986-01-24

Family

ID=19729780

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ202708A NZ202708A (en) 1981-12-08 1982-12-03 N-(vinblastinoyl-23)derivatives of amino acids,their preparation and pharmaceutical compositions

Country Status (24)

Country Link
JP (1) JPS58116491A (nl)
AT (1) AT390958B (nl)
AU (1) AU564951B2 (nl)
BE (1) BE895262A (nl)
CA (1) CA1198422A (nl)
CH (1) CH655727A5 (nl)
DD (1) DD205906A5 (nl)
DE (1) DE3245269A1 (nl)
DK (1) DK161833C (nl)
ES (1) ES517942A0 (nl)
FR (1) FR2517680B1 (nl)
GB (1) GB2111055B (nl)
GR (1) GR77280B (nl)
HU (1) HU187803B (nl)
IE (1) IE55283B1 (nl)
IL (1) IL67366A (nl)
IT (1) IT1157126B (nl)
LU (1) LU83822A1 (nl)
NL (1) NL8204711A (nl)
NZ (1) NZ202708A (nl)
OA (1) OA07270A (nl)
PT (1) PT75949B (nl)
SE (1) SE452622B (nl)
ZA (1) ZA828823B (nl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE64396T1 (de) * 1983-04-29 1991-06-15 Omnichem Sa Konjugierte vinblastin-verbindungen und ihre derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
US4675400A (en) * 1985-06-17 1987-06-23 Eli Lilly And Company Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids
US4667030A (en) * 1985-06-17 1987-05-19 Eli Lilly And Company Hydrazide succinimide derivatives of antineoplastic indole-dihydroindole alkaloids
CA1335686C (fr) * 1986-01-13 1995-05-23 Rao K. S. P. Bhushana Vinblastine et composition pharmaceutique les contenant
US4906086A (en) * 1987-06-19 1990-03-06 Honda Giken Kogyo Kabushiki Kaisha Rearview mirror device for motorcycles
FR2626882B1 (fr) * 1988-02-08 1991-11-08 Ire Celltarg Sa Conjugues de derives de vinca comportant une chaine detergente en position c-3
AU2014253584B2 (en) * 2013-04-19 2017-02-02 Jinan University Vinca Alkaloid Derivatives, Preparation Method therefor and Application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
US3848234A (en) * 1973-04-04 1974-11-12 Sperry Rand Corp Multi-processor system with multiple cache memories
IL48685A (en) * 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
OA06421A (fr) * 1980-06-10 1981-09-30 Omnium Chimique Sa Procédé de préparation de dérivés N-(vinblastinoyl-23) d'acides aminés et de peptides.

Also Published As

Publication number Publication date
GB2111055B (en) 1985-07-10
DK161833C (da) 1992-01-20
DE3245269A1 (de) 1983-07-21
SE452622B (sv) 1987-12-07
CH655727A5 (fr) 1986-05-15
ES8401768A1 (es) 1984-01-01
BE895262A (fr) 1983-06-07
IL67366A0 (en) 1983-03-31
GB2111055A (en) 1983-06-29
DD205906A5 (de) 1984-01-11
ES517942A0 (es) 1984-01-01
AU9084782A (en) 1983-06-16
LU83822A1 (fr) 1983-09-01
DK161833B (da) 1991-08-19
ZA828823B (en) 1983-09-28
OA07270A (fr) 1984-04-30
AT390958B (de) 1990-07-25
SE8206981D0 (sv) 1982-12-07
IL67366A (en) 1987-01-30
IT1157126B (it) 1987-02-11
IE55283B1 (en) 1990-08-01
CA1198422A (en) 1985-12-24
DK541882A (da) 1983-06-09
FR2517680B1 (fr) 1990-05-25
JPS58116491A (ja) 1983-07-11
AU564951B2 (en) 1987-09-03
SE8206981L (sv) 1983-06-09
PT75949B (fr) 1985-10-04
PT75949A (fr) 1983-01-01
NL8204711A (nl) 1983-07-01
HU187803B (en) 1986-02-28
ATA444982A (de) 1990-01-15
JPH0449557B2 (nl) 1992-08-11
FR2517680A1 (fr) 1983-06-10
GR77280B (nl) 1984-09-11
IE822906L (en) 1983-06-08
IT8268431A0 (it) 1982-12-07

Similar Documents

Publication Publication Date Title
US4388305A (en) Vinblastin-23-oyl amino acid derivatives for use as antitumor agents
US4639456A (en) Vinblastin-23-oyl amino acid derivatives
US4203898A (en) Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
DK141511B (da) Analogifremgangsmåde til fremstilling af derivater af vindblastin, leurosidin eller leurocristin.
NZ202708A (en) N-(vinblastinoyl-23)derivatives of amino acids,their preparation and pharmaceutical compositions
EP0077460A2 (en) Purine compounds endowed with immunomodulating activity
CA1067073A (en) Amide derivatives of vlb, leurosidine, leurocristine and related dimeric alkaloid
US4831038A (en) Vinblastine derivatives and pharmaceutical composition containing them
US4191688A (en) Amides of leurosine, leuroformine, desacetylleurosine and desacetylleuroformine
IE45558B1 (en) C3-carboxamido derivatives of vinblastine and related alkaloids
JP2952829B2 (ja) プラジミシンアミド誘導体
EP0428132B1 (en) Pradimicin derivatives
KR840002164B1 (ko) 빈카로이코블라스틴 유도체의 제조방법
JPH0210836B2 (nl)
KR850001919B1 (ko) 20'-하이드록시 빈블라스틴 및 유사화합물의 제조방법
EP0033981A2 (en) Preparation of bridged catharanthus alkaloid dimers
Atherton et al. Syntheses of actinomycin and analogs. 9. Synthesis of acetinomycin D lactam,[1', 1'-bis (L-threo-. alpha.,. beta.-diaminobutyric acid)] actinomycin D
KR810001453B1 (ko) 인돌-디하이드로인돌 카복스 아마이드 이량체의 제조방법
KR790000810B1 (ko) 빈브라스틴 유도체의 제조방법
LU83034A1 (fr) Derives n-(vinblastinoyl-23) d'acides amines et de peptides, leur preparation et leur application therapeutique