NO996097L - Lag-3 spleis varianter - Google Patents

Lag-3 spleis varianter

Info

Publication number
NO996097L
NO996097L NO19996097A NO996097A NO996097L NO 996097 L NO996097 L NO 996097L NO 19996097 A NO19996097 A NO 19996097A NO 996097 A NO996097 A NO 996097A NO 996097 L NO996097 L NO 996097L
Authority
NO
Norway
Prior art keywords
nucleotidic
seq
code
sequences
layer
Prior art date
Application number
NO19996097A
Other languages
English (en)
Norwegian (no)
Other versions
NO996097D0 (no
Inventor
Frederic Triebel
Renato Mastrangeli
Sergio Romagnani
Original Assignee
Inst Nat Sante Rech Med
Roussy Inst Gustave
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med, Roussy Inst Gustave, Applied Research Systems filed Critical Inst Nat Sante Rech Med
Publication of NO996097D0 publication Critical patent/NO996097D0/no
Publication of NO996097L publication Critical patent/NO996097L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Mechanical Coupling Of Light Guides (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Protection Of Transformers (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
NO19996097A 1997-06-18 1999-12-09 Lag-3 spleis varianter NO996097L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97401404A EP0900841A1 (en) 1997-06-18 1997-06-18 LAG-3 splice variants
PCT/EP1998/003307 WO1998058059A1 (en) 1997-06-18 1998-06-03 Lag-3 splice variants

Publications (2)

Publication Number Publication Date
NO996097D0 NO996097D0 (no) 1999-12-09
NO996097L true NO996097L (no) 2000-02-17

Family

ID=8229784

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19996097A NO996097L (no) 1997-06-18 1999-12-09 Lag-3 spleis varianter

Country Status (18)

Country Link
EP (2) EP0900841A1 (es)
JP (1) JP2002505582A (es)
KR (1) KR100552526B1 (es)
CN (1) CN1181201C (es)
AT (1) ATE274057T1 (es)
AU (1) AU740147B2 (es)
BR (1) BR9810925A (es)
CA (1) CA2293735A1 (es)
DE (1) DE69825741T2 (es)
DK (1) DK0977856T3 (es)
EA (1) EA003086B1 (es)
EE (1) EE04378B1 (es)
ES (1) ES2227862T3 (es)
HK (1) HK1027377A1 (es)
IL (2) IL133544A0 (es)
NO (1) NO996097L (es)
PT (1) PT977856E (es)
WO (1) WO1998058059A1 (es)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030100359A1 (en) * 2000-10-04 2003-05-29 Loose Timothy C. Audio network for gaming machines
EP1295895B1 (en) * 2001-09-19 2011-08-10 Institut Gustave Roussy Peptides and proteins binding to glu-pro motifs, therapeutical compositions containing the same and applications thereof
SE0103423D0 (sv) * 2001-10-12 2001-10-12 Astrazeneca Ab Polymorphism
EP2388265A1 (en) * 2002-02-22 2011-11-23 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
US7867085B2 (en) 2003-01-16 2011-01-11 Wms Gaming Inc. Gaming machine environment having controlled audio and visual media presentation
US7367886B2 (en) 2003-01-16 2008-05-06 Wms Gaming Inc. Gaming system with surround sound
US7364508B2 (en) 2003-01-16 2008-04-29 Wms Gaming, Inc. Gaming machine environment having controlled audio and visual media presentation
US8313374B2 (en) 2003-02-14 2012-11-20 Wms Gaming Inc. Gaming machine having improved audio control architecture
EP1897548B2 (en) * 2003-02-28 2024-05-22 The Johns Hopkins University T cell regulation
FR2902101B1 (fr) * 2006-06-12 2012-12-28 Scras Peptides a activite anti-proliferative
WO2008063391A2 (en) 2006-11-10 2008-05-29 Wms Gaming Inc. Wagering games using multi-level gaming structure
AR072999A1 (es) 2008-08-11 2010-10-06 Medarex Inc Anticuerpos humanos que se unen al gen 3 de activacion linfocitaria (lag-3) y los usos de estos
AR091649A1 (es) 2012-07-02 2015-02-18 Bristol Myers Squibb Co Optimizacion de anticuerpos que se fijan al gen de activacion de linfocitos 3 (lag-3) y sus usos
US9412222B2 (en) 2013-09-20 2016-08-09 Igt Coordinated gaming machine attract via gaming machine cameras
EP3508502B1 (en) 2013-09-20 2023-04-26 Bristol-Myers Squibb Company Combination of anti-lag-3 antibodies and anti-pd-1 antibodies to treat tumors
JOP20200094A1 (ar) 2014-01-24 2017-06-16 Dana Farber Cancer Inst Inc جزيئات جسم مضاد لـ pd-1 واستخداماتها
AU2015229103C9 (en) 2014-03-14 2020-11-26 Immutep S.A.S Antibody molecules to LAG-3 and uses thereof
TWI693232B (zh) 2014-06-26 2020-05-11 美商宏觀基因股份有限公司 與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
JO3663B1 (ar) 2014-08-19 2020-08-27 Merck Sharp & Dohme الأجسام المضادة لمضاد lag3 وأجزاء ربط الأنتيجين
TWI773646B (zh) 2015-06-08 2022-08-11 美商宏觀基因股份有限公司 結合lag-3的分子和其使用方法
SI3456346T1 (sl) 2015-07-30 2021-11-30 Macrogenics, Inc. Molekule za vezavo PD-1 in LAG-3 in postopki za uporabo le-teh
TWI756187B (zh) 2015-10-09 2022-03-01 美商再生元醫藥公司 抗ｌａｇ３抗體及其用途
GEP20217328B (en) 2015-12-14 2021-12-10 Macrogenics Inc Bispecific molecules having immunoreactivity with pd-1 and ctla-4, and methods of use thereof
EP3399989B1 (en) 2015-12-16 2023-08-09 Merck Sharp & Dohme LLC Anti-lag3 antibodies and antigen-binding fragments
SG11201907208XA (en) 2017-02-10 2019-09-27 Regeneron Pharma Radiolabeled anti-lag3 antibodies for immuno-pet imaging
CN110720039A (zh) 2017-05-30 2020-01-21 百时美施贵宝公司 Lag-3阳性肿瘤的治疗
JP7301002B2 (ja) 2017-05-30 2023-06-30 ブリストル－マイヤーズ スクイブ カンパニー 抗ｌａｇ－３抗体または抗ｌａｇ－３抗体および抗ｐｄ－１もしくは抗ｐｄ－ｌ１抗体を含む組成物
MA55965A (fr) 2019-05-13 2022-03-23 Regeneron Pharma Combinaison d'inhibiteurs pd-1 et d'inhibiteurs lag-3 pour une efficacité améliorée dans le traitement du cancer

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0280710B1 (en) * 1986-08-21 1996-03-20 The Trustees Of Columbia University In The City Of New York Dna encoding the t cell surface protein t4 and use of fragments of t4 in the treatment of aids
FR2656800B1 (fr) * 1990-01-08 1992-05-15 Roussy Inst Gustave Nouvelles proteines produits par les lymphocytes humains, sequence d'adn codant pour ces proteines et applications pharmaceutiques et biologiques.
KR100257466B1 (ko) * 1994-05-06 2000-07-01 레지날드 쇼트버그 에스. 안토니우스-소도 Lag-3의 가용성 폴리펩타이드 절편 및 생산 방법 치료 조성물, 항-이디오타입 항체

Also Published As

Publication number Publication date
KR20010013539A (ko) 2001-02-26
EA003086B1 (ru) 2002-12-26
PT977856E (pt) 2005-01-31
CN1260833A (zh) 2000-07-19
WO1998058059A1 (en) 1998-12-23
HK1027377A1 (en) 2001-01-12
ES2227862T3 (es) 2005-04-01
EE9900581A (xx) 2000-08-15
KR100552526B1 (ko) 2006-02-14
CA2293735A1 (en) 1998-12-23
AU740147B2 (en) 2001-11-01
NO996097D0 (no) 1999-12-09
EE04378B1 (xx) 2004-10-15
IL133544A (en) 2006-12-31
DE69825741D1 (de) 2004-09-23
JP2002505582A (ja) 2002-02-19
EP0900841A1 (en) 1999-03-10
BR9810925A (pt) 2000-08-15
ATE274057T1 (de) 2004-09-15
DK0977856T3 (da) 2004-12-20
IL133544A0 (en) 2001-04-30
EA200000038A1 (ru) 2000-06-26
DE69825741T2 (de) 2005-09-01
AU8435598A (en) 1999-01-04
EP0977856B1 (en) 2004-08-18
EP0977856A1 (en) 2000-02-09
CN1181201C (zh) 2004-12-22

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