NO994266L - Hydrofile binære systemer for administrasjon av cyklosporin - Google Patents
Hydrofile binære systemer for administrasjon av cyklosporinInfo
- Publication number
- NO994266L NO994266L NO994266A NO994266A NO994266L NO 994266 L NO994266 L NO 994266L NO 994266 A NO994266 A NO 994266A NO 994266 A NO994266 A NO 994266A NO 994266 L NO994266 L NO 994266L
- Authority
- NO
- Norway
- Prior art keywords
- cyclosporin
- administration
- binary systems
- hydrophilic
- hydrophilic binary
- Prior art date
Links
- 108010036949 Cyclosporine Proteins 0.000 title abstract 2
- 229960001265 ciclosporin Drugs 0.000 title abstract 2
- 229930182912 cyclosporin Natural products 0.000 title abstract 2
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 title 1
- 229930105110 Cyclosporin A Natural products 0.000 title 1
- 229910002056 binary alloy Inorganic materials 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- -1 cyclosporine compound Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000004094 surface-active agent Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
- A61K38/13—Cyclosporins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Dispersion Chemistry (AREA)
- Virology (AREA)
- Transplantation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81637597A | 1997-03-12 | 1997-03-12 | |
| PCT/US1998/004927 WO1998040094A1 (en) | 1997-03-12 | 1998-03-12 | Hydrophilic binary systems for the administration of cyclosporine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO994266D0 NO994266D0 (no) | 1999-09-02 |
| NO994266L true NO994266L (no) | 1999-11-10 |
Family
ID=25220436
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO994266A NO994266L (no) | 1997-03-12 | 1999-09-02 | Hydrofile binære systemer for administrasjon av cyklosporin |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6008192A (cs) |
| EP (1) | EP0969856B1 (cs) |
| JP (2) | JP4718653B2 (cs) |
| KR (1) | KR100966245B1 (cs) |
| CN (1) | CN1309414C (cs) |
| AT (1) | ATE286403T1 (cs) |
| AU (1) | AU6461898A (cs) |
| BG (1) | BG64669B1 (cs) |
| BR (1) | BR9808656A (cs) |
| CA (1) | CA2284000C (cs) |
| CZ (1) | CZ301382B6 (cs) |
| DE (1) | DE69828496T2 (cs) |
| DK (1) | DK0969856T3 (cs) |
| ES (1) | ES2236891T3 (cs) |
| HU (1) | HU228855B1 (cs) |
| IL (2) | IL131609A0 (cs) |
| NO (1) | NO994266L (cs) |
| NZ (1) | NZ337316A (cs) |
| PL (1) | PL193414B1 (cs) |
| PT (1) | PT969856E (cs) |
| SI (1) | SI0969856T1 (cs) |
| SK (1) | SK282714B6 (cs) |
| TR (1) | TR199902199T2 (cs) |
| WO (1) | WO1998040094A1 (cs) |
Families Citing this family (70)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5766629A (en) | 1995-08-25 | 1998-06-16 | Sangstat Medical Corporation | Oral cyclosporin formulations |
| US5962019A (en) * | 1995-08-25 | 1999-10-05 | Sangstat Medical Corporation | Oral cyclosporin formulations |
| US6458373B1 (en) | 1997-01-07 | 2002-10-01 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
| JP2000516256A (ja) * | 1997-01-30 | 2000-12-05 | ノバルティス アクチエンゲゼルシャフト | サイクロスポリンａを含む無油医薬組成物 |
| IT1294205B1 (it) * | 1997-07-23 | 1999-03-24 | Farmigea Spa | Procedimento per la solubilizzazione in acqua e in veicoli acquosi di sostanze farmacologicamente attive |
| FR2771292B1 (fr) * | 1997-11-21 | 2000-02-18 | Ethypharm Lab Prod Ethiques | Spheroides contenant de la tiagabine, procede de preparation et compositions pharmaceutiques |
| US7030155B2 (en) | 1998-06-05 | 2006-04-18 | Sonus Pharmaceuticals, Inc. | Emulsion vehicle for poorly soluble drugs |
| JP2002531515A (ja) | 1998-12-11 | 2002-09-24 | ファーマソリューションズ・インコーポレイテッド | 水に難溶性の薬剤のための自己乳化組成物 |
| DE19859910C2 (de) * | 1998-12-23 | 2001-03-22 | Ratiopharm Gmbh | Orales Arzneimittel |
| DE69939335D1 (de) | 1998-12-30 | 2008-09-25 | Dexcel Ltd | Dispergierbares konzentrat zur verabreichung von cyclosporin |
| US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
| US6616942B1 (en) | 1999-03-29 | 2003-09-09 | Soft Gel Technologies, Inc. | Coenzyme Q10 formulation and process methodology for soft gel capsules manufacturing |
| US6057289A (en) * | 1999-04-30 | 2000-05-02 | Pharmasolutions, Inc. | Pharmaceutical composition comprising cyclosporin in association with a carrier in a self-emulsifying drug delivery system |
| GB9912476D0 (en) * | 1999-05-28 | 1999-07-28 | Novartis Ag | Organic compounds |
| US6309663B1 (en) * | 1999-08-17 | 2001-10-30 | Lipocine Inc. | Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents |
| GB2355656B (en) * | 1999-08-17 | 2004-04-07 | Galena As | Pharmaceutical compositions for oral and topical administration |
| US7732404B2 (en) | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
| AU2001247244B2 (en) * | 2000-02-28 | 2005-06-02 | Genesegues, Inc. | Nanocapsule encapsulation system and method |
| US6623734B2 (en) * | 2000-06-22 | 2003-09-23 | Soft Gel Technologies, Inc. | Super absorption coenzyme Q10 |
| ATE355854T1 (de) | 2000-08-03 | 2007-03-15 | Antares Pharma Ipl Ag | Neue zusammensetzung zur transdermalen und/oder transmukosalen wirkstoffanwendung mit geeignetem therapeutischen spiegel |
| US7198801B2 (en) | 2000-08-03 | 2007-04-03 | Antares Pharma Ipl Ag | Formulations for transdermal or transmucosal application |
| US8980290B2 (en) | 2000-08-03 | 2015-03-17 | Antares Pharma Ipl Ag | Transdermal compositions for anticholinergic agents |
| US6960563B2 (en) * | 2001-08-31 | 2005-11-01 | Morton Grove Pharmaceuticals, Inc. | Spontaneous emulsions containing cyclosporine |
| CA2461730C (en) * | 2001-10-19 | 2012-05-15 | Isotechnika Inc. | Novel cyclosporin analog microemulsion preconcentrates |
| EP1455753A1 (en) * | 2001-12-20 | 2004-09-15 | Bernard Charles Sherman | Pharmaceutical compositions comprising a cyclosporin, a hydrophilic surfactant and a lipophilic surfactant |
| EP1344523A1 (en) * | 2002-03-11 | 2003-09-17 | Warner-Lambert Company | Ibuprofen solution for hard gelatin capsules |
| US20050059583A1 (en) | 2003-09-15 | 2005-03-17 | Allergan, Inc. | Methods of providing therapeutic effects using cyclosporin components |
| EP1670325A1 (en) | 2003-09-29 | 2006-06-21 | Soft Gel Technologies, Inc. | SOLUBILIZED CoQ-10 |
| US8124072B2 (en) | 2003-09-29 | 2012-02-28 | Soft Gel Technologies, Inc. | Solubilized CoQ-10 |
| ES2377932T3 (es) | 2003-10-10 | 2012-04-03 | Ferring Bv | Formulación farmacéutica transdérmica para minimizar los residuos sobre la piel |
| JP2005255677A (ja) * | 2004-02-12 | 2005-09-22 | Nof Corp | シクロスポリン製剤 |
| US7425340B2 (en) | 2004-05-07 | 2008-09-16 | Antares Pharma Ipl Ag | Permeation enhancing compositions for anticholinergic agents |
| ITMI20041245A1 (it) * | 2004-06-22 | 2004-09-22 | Ibsa Inst Biochimique Sa | Composizioni farmaceutiche iniettabnili comprendenti diclofenac sodico e b-ciclodestrina |
| MX2007005124A (es) * | 2004-10-29 | 2007-06-22 | Novartis Ag | Composiciones farmaceuticas espontaneamente dispersables. |
| US7135455B2 (en) * | 2004-11-15 | 2006-11-14 | Allergan, Inc | Methods for the therapeutic use of cyclosporine components |
| US7151085B2 (en) * | 2004-11-15 | 2006-12-19 | Allergan, Inc. | Therapeutic methods using cyclosporine components |
| WO2007124250A2 (en) | 2006-04-21 | 2007-11-01 | Antares Pharma Ipl Ag | Methods of treating hot flashes with formulations for transdermal or transmucosal application |
| US8067399B2 (en) | 2005-05-27 | 2011-11-29 | Antares Pharma Ipl Ag | Method and apparatus for transdermal or transmucosal application of testosterone |
| US20070207107A1 (en) * | 2006-03-03 | 2007-09-06 | Gareth Winckle | Silicone based emulsions for topical drug delivery |
| US9561178B2 (en) * | 2006-07-25 | 2017-02-07 | Allergan, Inc. | Cyclosporin compositions |
| US8343541B2 (en) | 2007-03-15 | 2013-01-01 | Soft Gel Technologies, Inc. | Ubiquinol and alpha lipoic acid compositions |
| JP5135852B2 (ja) * | 2007-03-30 | 2013-02-06 | 日油株式会社 | 可溶化用組成物 |
| US20090130198A1 (en) * | 2007-11-21 | 2009-05-21 | Innopharmax Inc. | Pharmaceutical composition with enhanced bioavailability |
| US11304960B2 (en) | 2009-01-08 | 2022-04-19 | Chandrashekar Giliyar | Steroidal compositions |
| US8332007B2 (en) * | 2009-01-12 | 2012-12-11 | The Board Of Trustees Of The University Of Illinois | Quantitative three-dimensional mapping of oxygen tension |
| TWI474830B (en) * | 2010-02-04 | 2015-03-01 | Ophthalmic pharmaceutical composition in the dosage form of a low-irritating and translucent emulsion for the treatment of topical immunomodulator with anti-inflammatory effect of the eye or the surrounding or associated tissues thereof | |
| CN101897949B (zh) * | 2010-02-24 | 2016-07-06 | 温士顿医药股份有限公司 | 低刺激性透明乳化液剂型以供眼睛或眼睛周围有关组织表面免疫调节及消炎的眼用药物组合物 |
| US20120003162A1 (en) | 2010-06-30 | 2012-01-05 | Mcneil-Ppc, Inc. | Methods of Preparing Non-Alcohol Bioactive Esential Oil Mouth Rinses |
| US9084902B2 (en) | 2010-06-30 | 2015-07-21 | Mcneil-Ppc, Inc. | Non-alchohol bioactive essential oil mouth rinses |
| US9034858B2 (en) | 2010-11-30 | 2015-05-19 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US20180153904A1 (en) | 2010-11-30 | 2018-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US9358241B2 (en) | 2010-11-30 | 2016-06-07 | Lipocine Inc. | High-strength testosterone undecanoate compositions |
| US20120148675A1 (en) | 2010-12-10 | 2012-06-14 | Basawaraj Chickmath | Testosterone undecanoate compositions |
| WO2013082299A1 (en) | 2011-11-29 | 2013-06-06 | Als Therapy Development Institute | Targeting of t-lymphocytes to treat amyotrophic lateral sclerosis |
| KR101211902B1 (ko) * | 2012-04-30 | 2012-12-13 | 주식회사 휴온스 | 사이클로스포린 함유 무자극성 나노에멀젼 안약 조성물 |
| TW201536347A (zh) * | 2013-07-11 | 2015-10-01 | 參天製藥股份有限公司 | 含有環孢素ａ之水性眼科用組成物 |
| US20150352176A1 (en) * | 2014-06-06 | 2015-12-10 | Newport Research, Inc. | Oil-free and fat-free aqueous suspensions of cyclosporin |
| WO2016033556A1 (en) | 2014-08-28 | 2016-03-03 | Lipocine Inc. | BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS |
| US20170246187A1 (en) | 2014-08-28 | 2017-08-31 | Lipocine Inc. | (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE |
| CN107072963B (zh) | 2014-09-03 | 2020-07-07 | 吉倪塞思公司 | 治疗性纳米粒子和相关的组合物、方法和系统 |
| US20200237859A1 (en) * | 2019-01-25 | 2020-07-30 | Newport Research, Inc. | Aqueous suspensions of cyclosporin |
| US11324800B2 (en) * | 2015-01-15 | 2022-05-10 | Wellspring Ophthalmics, Inc. | Aqueous suspensions of cyclosporin |
| CN107969132B (zh) * | 2015-04-24 | 2020-08-25 | 日本帕卡濑精株式会社 | 水系表面处理剂、覆膜的制造方法和经表面处理的材料 |
| US20160361322A1 (en) | 2015-06-15 | 2016-12-15 | Lipocine Inc. | Composition and method for oral delivery of androgen prodrugs |
| CA3078723A1 (en) | 2016-11-28 | 2018-05-31 | Nachiappan Chidambaram | Oral testosterone undecanoate therapy |
| WO2019002362A1 (en) * | 2017-06-28 | 2019-01-03 | Spherium Biomed, S.L. | TOPICAL COMPOSITIONS OF CYCLOSPORIN A |
| CA3107214A1 (en) | 2018-07-20 | 2020-01-23 | Lipocine Inc. | Liver disease |
| JP2023548965A (ja) * | 2020-11-09 | 2023-11-21 | スカイ・セラピューティクス・カンパニー・リミテッド | 固相の物質及びこれを含む分散組成物 |
| JP2023548966A (ja) * | 2020-11-09 | 2023-11-21 | スカイ・セラピューティクス・カンパニー・リミテッド | 固相のシクロスポリンａ及びこれを含む分散組成物 |
| KR102665670B1 (ko) * | 2020-11-09 | 2024-05-13 | 주식회사 스카이테라퓨틱스 | 고상의 사이클로스포린 a 및 이를 포함하는 분산 조성물 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4117118A (en) * | 1976-04-09 | 1978-09-26 | Sandoz Ltd. | Organic compounds |
| FI65914C (fi) * | 1978-03-07 | 1984-08-10 | Sandoz Ag | Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a |
| GB8903804D0 (en) * | 1989-02-20 | 1989-04-05 | Sandoz Ltd | Improvements in or relating to organic compounds |
| HU201567B (en) * | 1988-07-21 | 1990-11-28 | Gyogyszerkutato Intezet | Process for production of intravenous medical compositions containing cyclosphorin |
| US5342625A (en) * | 1988-09-16 | 1994-08-30 | Sandoz Ltd. | Pharmaceutical compositions comprising cyclosporins |
| GB2230440B (en) * | 1989-02-09 | 1993-05-19 | Sandoz Ltd | Novel cyclosporin galenic forms |
| JPH037237A (ja) * | 1989-03-14 | 1991-01-14 | Sandoz Ag | シクロスポリン類投与の新規用途および治療手段 |
| HU208491B (en) * | 1990-11-27 | 1993-11-29 | Gyogyszerkutato Intezet | Process for producing oral pharmaceutical composition containing cyclosporin |
| GB9113872D0 (en) * | 1991-06-27 | 1991-08-14 | Sandoz Ag | Improvements in or relating to organic compounds |
| JPH0558906A (ja) * | 1991-09-06 | 1993-03-09 | Sankyo Co Ltd | シクロスポリン点眼製剤 |
| SK283442B6 (sk) * | 1993-04-20 | 2003-07-01 | Novartis Ag | Farmaceutický prípravok na orálne podanie |
| NZ247516A (en) * | 1993-04-28 | 1995-02-24 | Bernard Charles Sherman | Water dispersible pharmaceutical compositions comprising drug dissolved in solvent system comprising at least one alcohol and at least one surfactant |
| CN1077800C (zh) * | 1993-07-01 | 2002-01-16 | 韩美药品工业株式会社 | 环孢菌素软胶囊组合物 |
| DE4340781C3 (de) * | 1993-11-30 | 2000-01-27 | Novartis Ag | Cyclosporin enthaltende flüssige Zubereitungen und Verfahren zu ihrer Herstellung |
| US5766629A (en) * | 1995-08-25 | 1998-06-16 | Sangstat Medical Corporation | Oral cyclosporin formulations |
| MX9702809A (es) * | 1995-08-25 | 1998-02-28 | Sangstat Medical Corp | Formulaciones orales de ciclosporina. |
| JP2000516256A (ja) * | 1997-01-30 | 2000-12-05 | ノバルティス アクチエンゲゼルシャフト | サイクロスポリンａを含む無油医薬組成物 |
-
1998
- 1998-03-12 CZ CZ0312999A patent/CZ301382B6/cs not_active IP Right Cessation
- 1998-03-12 SK SK1199-99A patent/SK282714B6/sk not_active IP Right Cessation
- 1998-03-12 AU AU64618/98A patent/AU6461898A/en not_active Abandoned
- 1998-03-12 CA CA2284000A patent/CA2284000C/en not_active Expired - Fee Related
- 1998-03-12 BR BR9808656-1A patent/BR9808656A/pt not_active Application Discontinuation
- 1998-03-12 HU HU0001782A patent/HU228855B1/hu not_active IP Right Cessation
- 1998-03-12 EP EP98910361A patent/EP0969856B1/en not_active Expired - Lifetime
- 1998-03-12 ES ES98910361T patent/ES2236891T3/es not_active Expired - Lifetime
- 1998-03-12 AT AT98910361T patent/ATE286403T1/de active
- 1998-03-12 JP JP53982898A patent/JP4718653B2/ja not_active Expired - Fee Related
- 1998-03-12 KR KR1019997008610A patent/KR100966245B1/ko not_active Expired - Fee Related
- 1998-03-12 TR TR1999/02199T patent/TR199902199T2/xx unknown
- 1998-03-12 SI SI9830753T patent/SI0969856T1/xx unknown
- 1998-03-12 PT PT98910361T patent/PT969856E/pt unknown
- 1998-03-12 NZ NZ337316A patent/NZ337316A/en not_active IP Right Cessation
- 1998-03-12 DE DE69828496T patent/DE69828496T2/de not_active Expired - Lifetime
- 1998-03-12 WO PCT/US1998/004927 patent/WO1998040094A1/en active IP Right Grant
- 1998-03-12 US US09/041,881 patent/US6008192A/en not_active Expired - Lifetime
- 1998-03-12 IL IL13160998A patent/IL131609A0/xx unknown
- 1998-03-12 CN CNB988032651A patent/CN1309414C/zh not_active Expired - Fee Related
- 1998-03-12 DK DK98910361T patent/DK0969856T3/da active
- 1998-03-12 PL PL98335575A patent/PL193414B1/pl not_active IP Right Cessation
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1999
- 1999-08-26 IL IL131609A patent/IL131609A/en not_active IP Right Cessation
- 1999-09-02 NO NO994266A patent/NO994266L/no not_active Application Discontinuation
- 1999-10-08 BG BG103790A patent/BG64669B1/bg unknown
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2011
- 2011-02-01 JP JP2011019503A patent/JP2011105754A/ja active Pending
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