NO986100D0 - Androgene reseptormodulerende forbindelser og fremgangsmÕter - Google Patents
Androgene reseptormodulerende forbindelser og fremgangsmÕterInfo
- Publication number
- NO986100D0 NO986100D0 NO986100A NO986100A NO986100D0 NO 986100 D0 NO986100 D0 NO 986100D0 NO 986100 A NO986100 A NO 986100A NO 986100 A NO986100 A NO 986100A NO 986100 D0 NO986100 D0 NO 986100D0
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- androgen receptor
- methods
- disclosed
- modulating compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Endocrinology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Electrotherapy Devices (AREA)
- Steroid Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2199796P | 1996-06-27 | 1996-06-27 | |
PCT/US1997/011222 WO1997049709A1 (en) | 1996-06-27 | 1997-06-26 | Androgen receptor modulator compounds and methods |
Publications (3)
Publication Number | Publication Date |
---|---|
NO986100L NO986100L (no) | 1998-12-23 |
NO986100D0 true NO986100D0 (no) | 1998-12-23 |
NO311645B1 NO311645B1 (no) | 2001-12-27 |
Family
ID=21807289
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19986100A NO311645B1 (no) | 1996-06-27 | 1998-12-23 | Androgene reseptormodulerende forbindelser |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0918774B9 (no) |
JP (1) | JP2000513362A (no) |
AT (1) | ATE209207T1 (no) |
AU (1) | AU728178B2 (no) |
BR (1) | BR9710988A (no) |
DE (1) | DE69709752T2 (no) |
DK (1) | DK0918774T3 (no) |
ES (1) | ES2168650T3 (no) |
NO (1) | NO311645B1 (no) |
PT (1) | PT918774E (no) |
RU (1) | RU2214412C2 (no) |
WO (1) | WO1997049709A1 (no) |
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6253061B1 (en) | 1997-09-19 | 2001-06-26 | Richard J. Helferich | Systems and methods for delivering information to a transmitting and receiving device |
US7003304B1 (en) | 1997-09-19 | 2006-02-21 | Thompson Investment Group, Llc | Paging transceivers and methods for selectively retrieving messages |
US6826407B1 (en) | 1999-03-29 | 2004-11-30 | Richard J. Helferich | System and method for integrating audio and visual messaging |
US6636733B1 (en) | 1997-09-19 | 2003-10-21 | Thompson Trust | Wireless messaging method |
US6983138B1 (en) | 1997-12-12 | 2006-01-03 | Richard J. Helferich | User interface for message access |
US6472415B1 (en) * | 1998-12-18 | 2002-10-29 | Biophysica, Inc. | Androgen receptor suppressors in the therapy and diagnosis of prostate cancer, alopecia and other hyper-androgenic syndromes |
JP2003508402A (ja) | 1999-08-27 | 2003-03-04 | リガンド・ファーマシューティカルズ・インコーポレイテッド | アンドロゲン受容体モジュレーター化合物および方法 |
US6566372B1 (en) | 1999-08-27 | 2003-05-20 | Ligand Pharmaceuticals Incorporated | Bicyclic androgen and progesterone receptor modulator compounds and methods |
EP1212322A2 (en) | 1999-08-27 | 2002-06-12 | Ligand Pharmaceuticals Incorporated | 8-substituted-6-trifluoromethyl-9-pyrido[3,2-g]quinoline compounds as androgen receptor modulators |
CO5200852A1 (es) | 1999-09-14 | 2002-09-27 | Lilly Co Eli | Moduladores rxr con mejorado perfil farmacologico ceptores x de los retinoides |
CA2670236C (en) | 1999-09-30 | 2012-06-05 | Hollis-Eden Pharmaceuticals, Inc. | Therapeutic treatment of androgen receptor driven conditions |
WO2001059448A1 (fr) * | 2000-02-10 | 2001-08-16 | Chugai Seiyaku Kabushiki Kaisha | Procede de criblage d'un agent antiandrogene |
AU2002215609A1 (en) * | 2000-06-28 | 2002-01-08 | Bristol-Myers Squibb Company | Fused cyclic compounds as modulators of nuclear hormone receptor function |
US7018993B2 (en) | 2000-06-30 | 2006-03-28 | Chugai Seiyaku Kabushiki Kaisha | Antiandrogenic agent |
GEP20074144B (en) * | 2000-09-19 | 2007-07-10 | Bristol Myers Squibb Co | Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function |
US7026484B2 (en) | 2001-02-23 | 2006-04-11 | Ligand Pharmaceuticals Incorporated | Tricyclic androgen receptor modulator compounds and methods |
US7214690B2 (en) | 2001-02-23 | 2007-05-08 | Ligand Pharmaceuticals Incorporated | Tricyclic quinolinone and tricyclic quinoline androgen receptor modulator compounds and methods |
CA2463311A1 (en) * | 2001-10-19 | 2003-05-01 | Paul J. Coleman | Androgen receptor modulators and methods of use thereof |
AU2002367424A1 (en) * | 2001-12-28 | 2003-07-24 | Takeda Chemical Industries, Ltd. | Androgen receptor antagonists |
US7705182B2 (en) | 2002-02-28 | 2010-04-27 | University Of Tennessee Research Foundation | Multi-substituted selective androgen receptor modulators and methods of use thereof |
CA2484340C (en) * | 2002-04-26 | 2011-05-03 | Ortho-Mcneil Pharmaceutical, Inc. | 2-(quinolonyl)-fused heterocycles as androgen receptor modulators |
US7405234B2 (en) | 2002-05-17 | 2008-07-29 | Bristol-Myers Squibb Company | Bicyclic modulators of androgen receptor function |
DE20301728U1 (de) | 2002-10-11 | 2004-03-11 | Ligand Pharmaceuticals, Inc., San Diego | 5-substituierte 7,9-Difluor-5H-Chromeno(3,4-f) -Chinolin-Verbindungen als selektive Progesteronrezeptormodulator-Verbindungen |
EP1567487A4 (en) | 2002-11-15 | 2005-11-16 | Bristol Myers Squibb Co | OPEN-CHAINED, PROLYL-FROSTED MODULATORS OF ANDROGEN RECEPTOR FUNCTION |
BRPI0406778A (pt) * | 2003-01-17 | 2006-01-17 | Warner Lambert Co | Antagonistas de receptores de androgênio |
MXPA06001751A (es) | 2003-08-22 | 2006-05-12 | Ligand Pharm Inc | Derivados de 6-cicloamino-2-quinolinona como compuestos moduladores de receptor de androgeno. |
US7256208B2 (en) | 2003-11-13 | 2007-08-14 | Bristol-Myers Squibb Company | Monocyclic N-Aryl hydantoin modulators of androgen receptor function |
US7820702B2 (en) | 2004-02-04 | 2010-10-26 | Bristol-Myers Squibb Company | Sulfonylpyrrolidine modulators of androgen receptor function and method |
US7696241B2 (en) | 2004-03-04 | 2010-04-13 | Bristol-Myers Squibb Company | Bicyclic compounds as modulators of androgen receptor function and method |
US7388027B2 (en) | 2004-03-04 | 2008-06-17 | Bristol-Myers Squibb Company | Bicyclic compounds as modulators of androgen receptor function and method |
US7625923B2 (en) | 2004-03-04 | 2009-12-01 | Bristol-Myers Squibb Company | Bicyclic modulators of androgen receptor function |
US8519158B2 (en) | 2004-03-12 | 2013-08-27 | Ligand Pharmaceuticals Incorporated | Androgen receptor modulator compounds and methods |
AU2007212191B2 (en) * | 2006-02-10 | 2011-12-22 | Janssen Pharmaceutica N.V. | Novel imidazolopyrazole derivatives useful as selective androgen receptor modulators |
US8268872B2 (en) | 2008-02-22 | 2012-09-18 | Radius Health, Inc. | Selective androgen receptor modulators |
MX2010009162A (es) | 2008-02-22 | 2010-12-21 | Radius Health Inc | Moduladores selectivos del receptor de androgeno. |
EP2130831A1 (en) | 2008-06-06 | 2009-12-09 | InterMed Discovery GmbH | CDC25 inhibitors |
CN102414213B (zh) * | 2009-04-30 | 2014-12-24 | 日产化学工业株式会社 | 三环苯并吡喃化合物的新的晶形及其制造方法 |
EP2531029B1 (en) | 2010-02-04 | 2016-10-19 | Radius Health, Inc. | Selective androgen receptor modulators |
ME02474B (me) | 2010-05-12 | 2017-02-20 | Radius Health Inc | Terapijski režimi |
US8642632B2 (en) | 2010-07-02 | 2014-02-04 | Radius Health, Inc. | Selective androgen receptor modulators |
BR112013007685B1 (pt) | 2010-09-28 | 2021-11-09 | Radius Pharmaceuticals, Inc | Compostos moduladores de receptor andrógeno seletivos, composição farmacêutica compreendendo os referidos compostos, método de identificação de um composto capaz de modular um receptor andrógeno, usos de um composto ou da composição e processo para a preparação de um composto |
EP2665493B1 (en) | 2011-01-20 | 2018-03-21 | Board Of Regents, The University Of Texas System | Mri markers, delivery and extraction systems, and methods of manufacture and use thereof |
US9421264B2 (en) | 2014-03-28 | 2016-08-23 | Duke University | Method of treating cancer using selective estrogen receptor modulators |
EP4035664A3 (en) | 2014-03-28 | 2022-11-30 | Duke University | Treating cancer using selective estrogen receptor modulators |
RU2769527C2 (ru) | 2016-06-22 | 2022-04-01 | Эллипсес Фарма Лтд | Способы лечения ar+ рака молочной железы |
CN106397317B (zh) * | 2016-09-26 | 2019-03-22 | 天津师范大学 | 1,2,3,4-四氢喹啉化合物及其合成方法与应用 |
CN106565723B (zh) * | 2016-11-04 | 2019-08-27 | 江苏师范大学 | 一种呋喃并吡啶、苯并吡啶类衍生化合物的制备方法 |
KR102322802B1 (ko) | 2017-01-05 | 2021-11-04 | 래디어스 파마슈티컬스, 인코포레이티드 | Rad1901-2hcl의 다형 형태 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2959839B2 (ja) * | 1989-07-07 | 1999-10-06 | アンドルシェルシュ・インコーポレイテッド | 性ステロイド活性の抑制における使用のためのアンドロゲン誘導体 |
US5677336A (en) * | 1993-10-21 | 1997-10-14 | Ligand Pharmaceuticals Incorporated | Non-steroid androgen receptor antagonist compounds and methods |
NZ300739A (en) * | 1994-12-22 | 2000-05-26 | Ligand Pharm Inc | Steroid receptor modulator compounds |
-
1997
- 1997-06-26 DE DE69709752T patent/DE69709752T2/de not_active Expired - Fee Related
- 1997-06-26 BR BR9710988-6A patent/BR9710988A/pt not_active IP Right Cessation
- 1997-06-26 WO PCT/US1997/011222 patent/WO1997049709A1/en active IP Right Grant
- 1997-06-26 ES ES97931460T patent/ES2168650T3/es not_active Expired - Lifetime
- 1997-06-26 AU AU35084/97A patent/AU728178B2/en not_active Ceased
- 1997-06-26 EP EP97931460A patent/EP0918774B9/en not_active Expired - Lifetime
- 1997-06-26 DK DK97931460T patent/DK0918774T3/da active
- 1997-06-26 JP JP10503562A patent/JP2000513362A/ja not_active Ceased
- 1997-06-26 RU RU99101057/04A patent/RU2214412C2/ru not_active IP Right Cessation
- 1997-06-26 PT PT97931460T patent/PT918774E/pt unknown
- 1997-06-26 AT AT97931460T patent/ATE209207T1/de not_active IP Right Cessation
-
1998
- 1998-12-23 NO NO19986100A patent/NO311645B1/no unknown
Also Published As
Publication number | Publication date |
---|---|
BR9710988A (pt) | 2002-01-15 |
PT918774E (pt) | 2002-05-31 |
AU3508497A (en) | 1998-01-14 |
ES2168650T3 (es) | 2002-06-16 |
EP0918774B1 (en) | 2001-11-21 |
NO311645B1 (no) | 2001-12-27 |
RU2214412C2 (ru) | 2003-10-20 |
EP0918774A1 (en) | 1999-06-02 |
WO1997049709A1 (en) | 1997-12-31 |
DK0918774T3 (da) | 2002-05-21 |
EP0918774B9 (en) | 2002-04-10 |
ATE209207T1 (de) | 2001-12-15 |
DE69709752T2 (de) | 2002-07-18 |
NO986100L (no) | 1998-12-23 |
AU728178B2 (en) | 2001-01-04 |
DE69709752D1 (de) | 2002-02-21 |
JP2000513362A (ja) | 2000-10-10 |
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