CA2259031A1 - Androgen receptor modulator compounds and methods - Google Patents
Androgen receptor modulator compounds and methodsInfo
- Publication number
- CA2259031A1 CA2259031A1 CA002259031A CA2259031A CA2259031A1 CA 2259031 A1 CA2259031 A1 CA 2259031A1 CA 002259031 A CA002259031 A CA 002259031A CA 2259031 A CA2259031 A CA 2259031A CA 2259031 A1 CA2259031 A1 CA 2259031A1
- Authority
- CA
- Canada
- Prior art keywords
- compounds
- androgen receptor
- methods
- receptor modulator
- disclosed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 3
- 239000000849 selective androgen receptor modulator Substances 0.000 title abstract 2
- 229940124011 Androgen receptor agonist Drugs 0.000 abstract 1
- 102000001307 androgen receptors Human genes 0.000 abstract 1
- 108010080146 androgen receptors Proteins 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000004031 partial agonist Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Landscapes
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Non-steroidal compounds which are high affinity, high selectivity modulators for androgen receptors are disclosed, having the formula:
(see formula I, III, IV, V) (see formula VI) Also disclosed are pharmaceutical compositions incorporating such compounds, methods for employing the disclosed compounds and compositions for treating patients requiring androgen receptor agonist, partial agonist or antagonist therapy, intermediates usefully in the preparation of the compounds and processes for the preparation of the androgen receptor modulator compounds.
(see formula I, III, IV, V) (see formula VI) Also disclosed are pharmaceutical compositions incorporating such compounds, methods for employing the disclosed compounds and compositions for treating patients requiring androgen receptor agonist, partial agonist or antagonist therapy, intermediates usefully in the preparation of the compounds and processes for the preparation of the androgen receptor modulator compounds.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2199796P | 1996-06-27 | 1996-06-27 | |
US60/021,997 | 1996-06-27 | ||
PCT/US1997/011222 WO1997049709A1 (en) | 1996-06-27 | 1997-06-26 | Androgen receptor modulator compounds and methods |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2259031A1 true CA2259031A1 (en) | 1997-12-31 |
CA2259031C CA2259031C (en) | 2006-10-24 |
Family
ID=37388423
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA002259031A Expired - Fee Related CA2259031C (en) | 1996-06-27 | 1997-06-26 | Androgen receptor modulator compounds and methods |
Country Status (1)
Country | Link |
---|---|
CA (1) | CA2259031C (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7727980B2 (en) | 2001-02-23 | 2010-06-01 | Ligand Pharmaceuticals Incorporated | Tricyclic androgen receptor modulator compounds and methods |
-
1997
- 1997-06-26 CA CA002259031A patent/CA2259031C/en not_active Expired - Fee Related
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7727980B2 (en) | 2001-02-23 | 2010-06-01 | Ligand Pharmaceuticals Incorporated | Tricyclic androgen receptor modulator compounds and methods |
Also Published As
Publication number | Publication date |
---|---|
CA2259031C (en) | 2006-10-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |