NO982503L - FremgangsmÕte ved fremstilling av dioksoazabicykloheksaner - Google Patents

FremgangsmÕte ved fremstilling av dioksoazabicykloheksaner

Info

Publication number
NO982503L
NO982503L NO982503A NO982503A NO982503L NO 982503 L NO982503 L NO 982503L NO 982503 A NO982503 A NO 982503A NO 982503 A NO982503 A NO 982503A NO 982503 L NO982503 L NO 982503L
Authority
NO
Norway
Prior art keywords
formula
compound
organic solvent
base
preparation
Prior art date
Application number
NO982503A
Other languages
English (en)
Other versions
NO982503D0 (no
Inventor
Stephen James Ray
John Arthur Rumpus
Original Assignee
Pfizer Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Res & Dev filed Critical Pfizer Res & Dev
Publication of NO982503L publication Critical patent/NO982503L/no
Publication of NO982503D0 publication Critical patent/NO982503D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Fremgangsmåte ved fremstilling av en forbindelse med formel (I), hvor R betyr CVCs-alkyl, C3-C6-cykloalkyl eller benzyl, og hvor fenyldelen av benzylgruppen valg- fritt kan være substituert med en eller flere substitu- enter som hver uavhengig velges fra halogen, nitrogen, Ci-Cj-alkyl, Ci-C^alkoksy, amino og trifluormetyl, omfattende å tilsette en oppløsning som inneholder en forbindelse med formel (II), et halogerinitrometan og et organisk oppløsningsmiddel utvalgt fra aceton, dimetyl- formamid, dimetylacetamid, acetonitril, dimetylsulf- oksid, N-metylpyrrolidinon og dimetoksyetan. I formel (II), hvor R har den ovennevnte betydning, til en blan- ding omfattende en base og et organisk oppløsningsmid- del, idet det organiske oppløsningsmiddel er som beskrevet ovenfor, og basen velges fra kaliumkarbonat, natriumkarbonat, cesiumkarbonat, trinatriumfosfat og kaliumfluorid, således at det dannes en forbindelse med formel (I), idet et eventuelt overskudd av base fjernes fra reaksjonsblandingen før produktet (I) isoleres.
NO982503A 1995-11-30 1998-06-02 FremgangsmÕte ved fremstilling av dioksoazabicykloheksaner NO982503D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9524466.1A GB9524466D0 (en) 1995-11-30 1995-11-30 Process
PCT/EP1996/004782 WO1997019921A1 (en) 1995-11-30 1996-10-31 Process for preparing dioxoazabicyclohexanes

Publications (2)

Publication Number Publication Date
NO982503L true NO982503L (no) 1998-06-02
NO982503D0 NO982503D0 (no) 1998-06-02

Family

ID=10784676

Family Applications (1)

Application Number Title Priority Date Filing Date
NO982503A NO982503D0 (no) 1995-11-30 1998-06-02 FremgangsmÕte ved fremstilling av dioksoazabicykloheksaner

Country Status (40)

Country Link
EP (1) EP0863874B1 (no)
JP (1) JP2000507919A (no)
KR (1) KR100286157B1 (no)
CN (1) CN1203588A (no)
AP (1) AP746A (no)
AR (1) AR004766A1 (no)
AT (1) ATE198325T1 (no)
AU (1) AU707221B2 (no)
BG (1) BG102484A (no)
BR (1) BR9611833A (no)
CA (1) CA2231590A1 (no)
CO (1) CO4480102A1 (no)
CZ (1) CZ162298A3 (no)
DE (1) DE69611380T2 (no)
DK (1) DK0863874T3 (no)
ES (1) ES2152571T3 (no)
GB (1) GB9524466D0 (no)
GR (1) GR3035341T3 (no)
HR (1) HRP960555A2 (no)
HU (1) HUP9903571A3 (no)
IL (1) IL123561A0 (no)
IS (1) IS4707A (no)
MA (1) MA24015A1 (no)
MX (1) MX9804311A (no)
MY (1) MY132595A (no)
NO (1) NO982503D0 (no)
NZ (1) NZ321968A (no)
OA (1) OA10692A (no)
PE (1) PE24898A1 (no)
PL (1) PL326978A1 (no)
PT (1) PT863874E (no)
RU (1) RU2156238C2 (no)
SK (1) SK70798A3 (no)
TN (1) TNSN96145A1 (no)
TR (1) TR199800957T2 (no)
TW (1) TW401397B (no)
UY (1) UY24379A1 (no)
WO (1) WO1997019921A1 (no)
YU (1) YU63196A (no)
ZA (1) ZA9610053B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1087617A (ja) * 1996-07-09 1998-04-07 Pfizer Inc キノリン系抗生物質の合成に有用な中間体の製法
HN1998000106A (es) 1997-08-01 1999-01-08 Pfizer Prod Inc Composiciones parenterales de alatroflaxacino
US7019142B2 (en) 1998-01-16 2006-03-28 Pfizer Inc. Process for preparing naphthyridones and intermediates
AU2002246295A1 (en) * 2002-03-25 2003-10-08 Council Of Scientific And Industrial Research Protein profiling of hyper acidic plants
NL2000192C2 (nl) * 2006-08-23 2008-02-26 Veenvoort B V De Stabiel bitumenschuim en de bereiding en het gebruik ervan.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256791A (en) * 1992-03-02 1993-10-26 Pfizer Inc. Preparation of intermediates in the synthesis of quinoline antibiotics
CN1141634A (zh) * 1994-01-18 1997-01-29 辉瑞大药厂 萘啶酮羧酸盐的制备方法和中间体

Also Published As

Publication number Publication date
PT863874E (pt) 2001-04-30
DK0863874T3 (da) 2001-01-29
KR19990071616A (ko) 1999-09-27
WO1997019921A1 (en) 1997-06-05
AU7562996A (en) 1997-06-19
OA10692A (en) 2000-11-06
CZ162298A3 (cs) 1999-03-17
PL326978A1 (en) 1998-11-09
HUP9903571A3 (en) 2001-01-29
JP2000507919A (ja) 2000-06-27
TR199800957T2 (xx) 1998-09-21
BG102484A (en) 1999-03-31
YU63196A (sh) 1998-11-05
RU2156238C2 (ru) 2000-09-20
BR9611833A (pt) 1999-03-09
NO982503D0 (no) 1998-06-02
DE69611380D1 (de) 2001-02-01
ZA9610053B (en) 1998-05-29
CN1203588A (zh) 1998-12-30
EP0863874A1 (en) 1998-09-16
GB9524466D0 (en) 1996-01-31
MA24015A1 (fr) 1997-07-01
HRP960555A2 (en) 1998-02-28
CO4480102A1 (es) 1997-07-09
PE24898A1 (es) 1998-06-02
MX9804311A (es) 1998-09-30
AU707221B2 (en) 1999-07-08
AP9600885A0 (en) 1997-01-31
AP746A (en) 1999-04-29
HUP9903571A2 (hu) 2000-03-28
ATE198325T1 (de) 2001-01-15
GR3035341T3 (en) 2001-05-31
KR100286157B1 (ko) 2001-04-16
CA2231590A1 (en) 1997-06-05
MY132595A (en) 2007-10-31
EP0863874B1 (en) 2000-12-27
SK70798A3 (en) 1999-06-11
UY24379A1 (es) 1997-05-20
TNSN96145A1 (fr) 2005-03-15
ES2152571T3 (es) 2001-02-01
NZ321968A (en) 1999-05-28
AR004766A1 (es) 1999-03-10
IS4707A (is) 1998-03-31
TW401397B (en) 2000-08-11
IL123561A0 (en) 1998-10-30
DE69611380T2 (de) 2001-04-26

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