FI884087A - Foerfarande foer framstaellning av metylenderivat av androsta-1,4-dien-3,17-dion. - Google Patents

Foerfarande foer framstaellning av metylenderivat av androsta-1,4-dien-3,17-dion. Download PDF

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Publication number
FI884087A
FI884087A FI884087A FI884087A FI884087A FI 884087 A FI884087 A FI 884087A FI 884087 A FI884087 A FI 884087A FI 884087 A FI884087 A FI 884087A FI 884087 A FI884087 A FI 884087A
Authority
FI
Finland
Prior art keywords
methylendering
androsta
dion
dien
formulation
Prior art date
Application number
FI884087A
Other languages
English (en)
Other versions
FI884087A0 (fi
Inventor
Antonio Longo
Paolo Lombardi
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of FI884087A0 publication Critical patent/FI884087A0/fi
Publication of FI884087A publication Critical patent/FI884087A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
FI884087A 1987-09-11 1988-09-06 Foerfarande foer framstaellning av metylenderivat av androsta-1,4-dien-3,17-dion. FI884087A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878721383A GB8721383D0 (en) 1987-09-11 1987-09-11 Preparation of methylene derivatives

Publications (2)

Publication Number Publication Date
FI884087A0 FI884087A0 (fi) 1988-09-06
FI884087A true FI884087A (fi) 1989-03-12

Family

ID=10623618

Family Applications (1)

Application Number Title Priority Date Filing Date
FI884087A FI884087A (fi) 1987-09-11 1988-09-06 Foerfarande foer framstaellning av metylenderivat av androsta-1,4-dien-3,17-dion.

Country Status (16)

Country Link
US (1) US4876045A (fi)
EP (1) EP0307134B1 (fi)
JP (1) JP2791046B2 (fi)
KR (1) KR970005315B1 (fi)
AT (1) ATE78488T1 (fi)
AU (1) AU602608B2 (fi)
CA (1) CA1316914C (fi)
DE (1) DE3872995T2 (fi)
ES (1) ES2051858T3 (fi)
FI (1) FI884087A (fi)
GB (1) GB8721383D0 (fi)
GR (1) GR3005296T3 (fi)
HU (1) HU199156B (fi)
IL (1) IL87657A (fi)
SU (1) SU1681731A3 (fi)
UA (1) UA6044A1 (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9201224D0 (en) * 1992-01-21 1992-03-11 Erba Carlo Spa Difluoromethylenandrostenone derivatives and process for their preparation
WO2001004342A1 (en) * 1999-07-07 2001-01-18 Pharmacia & Upjohn Company Process to prepare exemestane
CN1304413C (zh) * 2002-10-24 2007-03-14 上海华拓医药科技发展有限公司 一种抗癌药物依西美坦制备方法
US8183401B2 (en) * 2004-01-16 2012-05-22 Cedarburg Pharmaceuticals, Inc. Exemestane and its intermediates and methods of making the same
US10174070B2 (en) 2005-09-30 2019-01-08 Endece Llc 6-substituted estradiol derivatives and methods of use
US20070225354A1 (en) * 2006-03-21 2007-09-27 Eric Marchewitz Use of dihydrolipoamide for enhancing physical performance
US7569719B1 (en) * 2006-10-25 2009-08-04 Loctite (R&D) Limited Method of preparing electron deficient olefins
US20080275259A1 (en) * 2007-05-04 2008-11-06 Scinopharm Taiwan, Ltd Process for preparing aromatase inhibitors
SI2170329T1 (sl) * 2007-06-25 2015-03-31 Scinopharm Taiwan Ltd. Postopek za izdelavo kristaliničnega polimorfa 7-etil-10-hidroksikamptotecina
CN101686969A (zh) * 2007-06-25 2010-03-31 台湾神隆股份有限公司 依西美坦的多晶型物
CA2703596A1 (en) * 2007-10-24 2009-04-30 Loctite (R&D) Limited Activated methylene reagents and curable compositions prepared therefrom
US8686105B2 (en) 2007-10-24 2014-04-01 Henkel IP & Holding GmbH Adhesive systems using imines and salts thereof, precursors to electron deficient olefins and coreactants therefor
US7973119B1 (en) 2007-10-24 2011-07-05 Loctite (R&D) Limited Adhesive systems using imines and salts thereof and precursurs to electron deficient olefins
US8053589B1 (en) * 2007-10-24 2011-11-08 Henkel Ireland Limited Imines and methods of preparing electron deficient olefins using such novel imines
JP5639892B2 (ja) 2007-10-24 2014-12-10 ヘンケル アイルランド リミテッド 電子欠損オレフィン
US10196471B1 (en) 2008-10-24 2019-02-05 Henkel IP & Holding GmbH Curable composition having an electron deficient olefin
US8399698B1 (en) 2008-10-24 2013-03-19 Henkel Ireland Limited Substituted activated methylene reagents and methods of using such reagents to form electron deficient olefins
EP2429299B1 (en) 2009-05-01 2016-06-01 Celloxess Llc Treating male infertility secondary to sperm oxidative stress
ES2605960T3 (es) 2010-09-14 2017-03-17 Endece, Llc Derivados de desmetil-estradiol 6-sustituido como agonistas del RE-beta
CN105085599A (zh) * 2014-05-16 2015-11-25 绍兴文理学院 一种依西美坦中间体17,17-乙二氧基-6-亚甲基雄甾-1,4-二烯-3-酮及其制备方法和应用
CN105294807A (zh) * 2014-06-26 2016-02-03 浙江医药股份有限公司新昌制药厂 一种依西美坦中间体肟化合物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3004508C2 (de) * 1980-02-05 1981-12-10 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur Herstellung von 6-Methylensteroiden
GB8517360D0 (en) * 1985-07-09 1985-08-14 Erba Farmitalia Substituted androsta-1,4-diene-3,17-diones

Also Published As

Publication number Publication date
EP0307134B1 (en) 1992-07-22
GB8721383D0 (en) 1987-10-21
DE3872995D1 (de) 1992-08-27
ATE78488T1 (de) 1992-08-15
SU1681731A3 (ru) 1991-09-30
AU2198088A (en) 1989-03-16
KR890005141A (ko) 1989-05-13
JPH01104095A (ja) 1989-04-21
UA6044A1 (uk) 1994-12-29
GR3005296T3 (fi) 1993-05-24
JP2791046B2 (ja) 1998-08-27
IL87657A0 (en) 1989-02-28
IL87657A (en) 1993-02-21
DE3872995T2 (de) 1992-12-10
AU602608B2 (en) 1990-10-18
ES2051858T3 (es) 1994-07-01
CA1316914C (en) 1993-04-27
HUT48273A (en) 1989-05-29
KR970005315B1 (ko) 1997-04-15
EP0307134A1 (en) 1989-03-15
HU199156B (en) 1990-01-29
US4876045A (en) 1989-10-24
FI884087A0 (fi) 1988-09-06

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Owner name: FARMITALIA CARLO ERBA S.R.L