UA6044A1 - Спосіб одержання метіленових похідних андроста-1,4 -діен-3,17-діона - Google Patents

Спосіб одержання метіленових похідних андроста-1,4 -діен-3,17-діона

Info

Publication number
UA6044A1
UA6044A1 UA4356486A UA4356486A UA6044A1 UA 6044 A1 UA6044 A1 UA 6044A1 UA 4356486 A UA4356486 A UA 4356486A UA 4356486 A UA4356486 A UA 4356486A UA 6044 A1 UA6044 A1 UA 6044A1
Authority
UA
Ukraine
Prior art keywords
androsta
dion
dien
methylene derivatives
producing methylene
Prior art date
Application number
UA4356486A
Other languages
English (en)
Russian (ru)
Inventor
Лонго Антоніо
Ломбарді Паоло
Original Assignee
Фарміталіа Карло Ерба С.Р.Л.
Фармиталиа Карло Эрба С.Р.Л.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фарміталіа Карло Ерба С.Р.Л., Фармиталиа Карло Эрба С.Р.Л. filed Critical Фарміталіа Карло Ерба С.Р.Л.
Publication of UA6044A1 publication Critical patent/UA6044A1/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)

Abstract

Спосіб одержання метиленових похідних андроста-1,4-дієн-3,17-діону загальної формули
UA4356486A 1987-09-11 1988-09-09 Спосіб одержання метіленових похідних андроста-1,4 -діен-3,17-діона UA6044A1 (uk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878721383A GB8721383D0 (en) 1987-09-11 1987-09-11 Preparation of methylene derivatives

Publications (1)

Publication Number Publication Date
UA6044A1 true UA6044A1 (uk) 1994-12-29

Family

ID=10623618

Family Applications (1)

Application Number Title Priority Date Filing Date
UA4356486A UA6044A1 (uk) 1987-09-11 1988-09-09 Спосіб одержання метіленових похідних андроста-1,4 -діен-3,17-діона

Country Status (16)

Country Link
US (1) US4876045A (uk)
EP (1) EP0307134B1 (uk)
JP (1) JP2791046B2 (uk)
KR (1) KR970005315B1 (uk)
AT (1) ATE78488T1 (uk)
AU (1) AU602608B2 (uk)
CA (1) CA1316914C (uk)
DE (1) DE3872995T2 (uk)
ES (1) ES2051858T3 (uk)
FI (1) FI884087A (uk)
GB (1) GB8721383D0 (uk)
GR (1) GR3005296T3 (uk)
HU (1) HU199156B (uk)
IL (1) IL87657A (uk)
SU (1) SU1681731A3 (uk)
UA (1) UA6044A1 (uk)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9201224D0 (en) * 1992-01-21 1992-03-11 Erba Carlo Spa Difluoromethylenandrostenone derivatives and process for their preparation
AU5873300A (en) * 1999-07-07 2001-01-30 Pharmacia & Upjohn Company Process to prepare exemestane
CN1304413C (zh) * 2002-10-24 2007-03-14 上海华拓医药科技发展有限公司 一种抗癌药物依西美坦制备方法
WO2005070951A1 (en) 2004-01-16 2005-08-04 Cedarburg Pharmaceuticals, Inc. Exemestane and its intermediates and methods of making the same
US10174070B2 (en) 2005-09-30 2019-01-08 Endece Llc 6-substituted estradiol derivatives and methods of use
US20070225354A1 (en) * 2006-03-21 2007-09-27 Eric Marchewitz Use of dihydrolipoamide for enhancing physical performance
US7569719B1 (en) * 2006-10-25 2009-08-04 Loctite (R&D) Limited Method of preparing electron deficient olefins
US20080275259A1 (en) * 2007-05-04 2008-11-06 Scinopharm Taiwan, Ltd Process for preparing aromatase inhibitors
CN101686969A (zh) * 2007-06-25 2010-03-31 台湾神隆股份有限公司 依西美坦的多晶型物
CN101686968B (zh) * 2007-06-25 2012-05-30 台湾神隆股份有限公司 7-乙基-10-羟基喜树碱的多晶型物
US8686105B2 (en) 2007-10-24 2014-04-01 Henkel IP & Holding GmbH Adhesive systems using imines and salts thereof, precursors to electron deficient olefins and coreactants therefor
CA2703603A1 (en) * 2007-10-24 2009-04-30 Loctite (R&D) Limited Electron deficient olefins
WO2009053482A2 (en) * 2007-10-24 2009-04-30 Loctite (R & D) Limited Activated methylene reagents and curable compositions prepared therefrom
US8053589B1 (en) * 2007-10-24 2011-11-08 Henkel Ireland Limited Imines and methods of preparing electron deficient olefins using such novel imines
US7973119B1 (en) 2007-10-24 2011-07-05 Loctite (R&D) Limited Adhesive systems using imines and salts thereof and precursurs to electron deficient olefins
US8399698B1 (en) 2008-10-24 2013-03-19 Henkel Ireland Limited Substituted activated methylene reagents and methods of using such reagents to form electron deficient olefins
US10196471B1 (en) 2008-10-24 2019-02-05 Henkel IP & Holding GmbH Curable composition having an electron deficient olefin
WO2010127297A1 (en) 2009-05-01 2010-11-04 Parviz Gharagozloo Treating male infertility secondary to sperm oxidative stress
AU2011302065B2 (en) 2010-09-14 2016-12-01 Endece, Llc 6-substituted demethyl-estradiol derivatives as ER-beta agonists
CN105085599A (zh) * 2014-05-16 2015-11-25 绍兴文理学院 一种依西美坦中间体17,17-乙二氧基-6-亚甲基雄甾-1,4-二烯-3-酮及其制备方法和应用
CN105294807A (zh) * 2014-06-26 2016-02-03 浙江医药股份有限公司新昌制药厂 一种依西美坦中间体肟化合物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3004508C2 (de) * 1980-02-05 1981-12-10 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur Herstellung von 6-Methylensteroiden
GB8517360D0 (en) * 1985-07-09 1985-08-14 Erba Farmitalia Substituted androsta-1,4-diene-3,17-diones

Also Published As

Publication number Publication date
SU1681731A3 (ru) 1991-09-30
AU2198088A (en) 1989-03-16
DE3872995D1 (de) 1992-08-27
ES2051858T3 (es) 1994-07-01
CA1316914C (en) 1993-04-27
GB8721383D0 (en) 1987-10-21
DE3872995T2 (de) 1992-12-10
EP0307134A1 (en) 1989-03-15
IL87657A0 (en) 1989-02-28
EP0307134B1 (en) 1992-07-22
KR970005315B1 (ko) 1997-04-15
US4876045A (en) 1989-10-24
GR3005296T3 (uk) 1993-05-24
FI884087A (fi) 1989-03-12
JPH01104095A (ja) 1989-04-21
AU602608B2 (en) 1990-10-18
HU199156B (en) 1990-01-29
IL87657A (en) 1993-02-21
ATE78488T1 (de) 1992-08-15
HUT48273A (en) 1989-05-29
KR890005141A (ko) 1989-05-13
JP2791046B2 (ja) 1998-08-27
FI884087A0 (fi) 1988-09-06

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