NO982304L - 25-Hydroksy-16-ene-26,27-bishomo-cholecalciferoler - Google Patents

25-Hydroksy-16-ene-26,27-bishomo-cholecalciferoler

Info

Publication number
NO982304L
NO982304L NO982304A NO982304A NO982304L NO 982304 L NO982304 L NO 982304L NO 982304 A NO982304 A NO 982304A NO 982304 A NO982304 A NO 982304A NO 982304 L NO982304 L NO 982304L
Authority
NO
Norway
Prior art keywords
bishomo
cholecalciferol
ene
hydroxy
Prior art date
Application number
NO982304A
Other languages
English (en)
Norwegian (no)
Other versions
NO982304D0 (no
Inventor
Jerome Anthony Iacobelli
Milan Radoje Uskokovic
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO982304D0 publication Critical patent/NO982304D0/no
Publication of NO982304L publication Critical patent/NO982304L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
    • C07C35/32—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system being a (4.3.0) system, e.g. indenols
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/292—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with chromium derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/30—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation
    • C07C45/305—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with halogen containing compounds, e.g. hypohalogenation with halogenochromate reagents, e.g. pyridinium chlorochromate
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/487—Saturated compounds containing a keto group being part of a ring containing hydroxy groups
    • C07C49/507—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic
    • C07C49/513—Saturated compounds containing a keto group being part of a ring containing hydroxy groups polycyclic a keto group being part of a condensed ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
NO982304A 1995-11-22 1998-05-20 25-Hydroksy-16-ene-26,27-bishomo-cholecalciferoler NO982304L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US874495P 1995-11-22 1995-11-22
PCT/EP1996/004954 WO1997019058A1 (en) 1995-11-22 1996-11-13 25-hydroxy-16-ene-26,27-bishomo-cholecalciferols

Publications (2)

Publication Number Publication Date
NO982304D0 NO982304D0 (no) 1998-05-20
NO982304L true NO982304L (no) 1998-07-07

Family

ID=21733405

Family Applications (1)

Application Number Title Priority Date Filing Date
NO982304A NO982304L (no) 1995-11-22 1998-05-20 25-Hydroksy-16-ene-26,27-bishomo-cholecalciferoler

Country Status (27)

Country Link
US (1) US6030963A (cs)
EP (1) EP0874814B1 (cs)
JP (2) JP3917184B2 (cs)
KR (1) KR19990071535A (cs)
CN (1) CN1076347C (cs)
AR (1) AR004726A1 (cs)
AT (1) ATE241599T1 (cs)
AU (1) AU705942B2 (cs)
BR (1) BR9611741A (cs)
CA (1) CA2237897C (cs)
CZ (1) CZ293489B6 (cs)
DE (1) DE69628458T2 (cs)
DK (1) DK0874814T3 (cs)
EA (1) EA002772B1 (cs)
ES (1) ES2198501T3 (cs)
HU (1) HUP9903715A3 (cs)
IL (1) IL124290A (cs)
MX (1) MX9803966A (cs)
MY (1) MY116582A (cs)
NO (1) NO982304L (cs)
NZ (1) NZ322035A (cs)
PL (1) PL186845B1 (cs)
PT (1) PT874814E (cs)
TR (1) TR199800908T2 (cs)
TW (1) TW403735B (cs)
WO (1) WO1997019058A1 (cs)
ZA (1) ZA969625B (cs)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939408A (en) * 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
GB9625271D0 (en) * 1996-12-04 1997-01-22 Leo Pharm Prod Ltd Chemical compounds
US5919986A (en) * 1997-10-17 1999-07-06 Hoffmann-La Roche Inc. D-homo vitamin D3 derivatives
BRPI0414701A (pt) * 2003-09-24 2006-11-14 Bioxell Spa uso de um composto de vitamina d, método de prevenção ou tratamnento de disfunção de bexiga em um paciente, composto de vitamina d, e, kit
GB2407499B (en) * 2003-11-03 2008-02-27 Bioxell Spa Vitamin D3 analogue for use in the treatment of BPH
US7332482B2 (en) * 2003-09-24 2008-02-19 Bioxell S.P.A. Method for treating benign prostatic hyperplasia
CH698144B1 (fr) * 2003-09-24 2009-05-29 Bioxell Spa Analogue de la vitamine D3
WO2006036813A2 (en) * 2004-09-24 2006-04-06 Bioxell S.P.A. 20-cycloalkyl,26,27-alkyl/haloalkyl vitamin d3 compounds and methods of use thereof
US20100009949A1 (en) * 2006-03-24 2010-01-14 Bioxell S.P.A. Novel method
WO2012118154A1 (ja) * 2011-03-02 2012-09-07 学校法人日本大学 パーシャルアゴニスト活性を持つ新規ビタミンd受容体モジュレーター

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA8923B (en) * 1988-01-20 1989-09-27 Hoffmann La Roche 16-dehydro-vitamin d3-derivatives
US5145846A (en) * 1988-01-20 1992-09-08 Hoffmann-La Roche Inc. Vitamin D3 analogs
US5087619A (en) * 1988-01-20 1992-02-11 Hoffman-La Roche Inc. Vitamin D3 analogs
TW267161B (cs) * 1992-11-20 1996-01-01 Hoffmann La Roche

Also Published As

Publication number Publication date
JP2007126458A (ja) 2007-05-24
CN1202885A (zh) 1998-12-23
PT874814E (pt) 2003-09-30
DE69628458D1 (de) 2003-07-03
NO982304D0 (no) 1998-05-20
EP0874814A1 (en) 1998-11-04
CZ157298A3 (cs) 1998-09-16
ZA969625B (en) 1997-05-22
JP3917184B2 (ja) 2007-05-23
WO1997019058A1 (en) 1997-05-29
IL124290A (en) 2002-09-12
MY116582A (en) 2004-02-28
CN1076347C (zh) 2001-12-19
KR19990071535A (ko) 1999-09-27
EA199800468A1 (ru) 1998-12-24
PL186845B1 (pl) 2004-03-31
AU705942B2 (en) 1999-06-03
ES2198501T3 (es) 2004-02-01
EA002772B1 (ru) 2002-08-29
AU7570296A (en) 1997-06-11
DK0874814T3 (da) 2003-09-22
DE69628458T2 (de) 2004-03-18
HUP9903715A2 (hu) 2000-03-28
BR9611741A (pt) 1999-02-23
ATE241599T1 (de) 2003-06-15
TR199800908T2 (xx) 2001-05-21
JP2000500476A (ja) 2000-01-18
CZ293489B6 (cs) 2004-05-12
PL326837A1 (en) 1998-10-26
NZ322035A (en) 1998-11-25
EP0874814B1 (en) 2003-05-28
CA2237897A1 (en) 1997-05-29
HUP9903715A3 (en) 2000-09-28
US6030963A (en) 2000-02-29
CA2237897C (en) 2006-01-03
TW403735B (en) 2000-09-01
MX9803966A (es) 1998-09-30
AR004726A1 (es) 1999-03-10

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