NO970059L - Antrasyklinforbindelse og framgangsmåte for framstilling derav - Google Patents

Antrasyklinforbindelse og framgangsmåte for framstilling derav

Info

Publication number
NO970059L
NO970059L NO970059A NO970059A NO970059L NO 970059 L NO970059 L NO 970059L NO 970059 A NO970059 A NO 970059A NO 970059 A NO970059 A NO 970059A NO 970059 L NO970059 L NO 970059L
Authority
NO
Norway
Prior art keywords
chosen
group
pct
preparation
sec
Prior art date
Application number
NO970059A
Other languages
English (en)
Other versions
NO305561B1 (no
NO970059D0 (no
Inventor
Fabio Animati
Federico Arcamone
Guiseppe Giannini
Paolo Lombardi
Edith Monteagudo
Original Assignee
Menarini Farma Ind
Bristol Myers Squibb Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Farma Ind, Bristol Myers Squibb Spa filed Critical Menarini Farma Ind
Publication of NO970059D0 publication Critical patent/NO970059D0/no
Publication of NO970059L publication Critical patent/NO970059L/no
Publication of NO305561B1 publication Critical patent/NO305561B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/24—Condensed ring systems having three or more rings
    • C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C46/00—Preparation of quinones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/26—Quinones containing groups having oxygen atoms singly bound to carbon atoms
    • C07C50/36—Quinones containing groups having oxygen atoms singly bound to carbon atoms the quinoid structure being part of a condensed ring system having four or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C50/00—Quinones
    • C07C50/38—Quinones containing —CHO or non—quinoid keto groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO970059A 1994-08-04 1997-01-08 Antrasyklinforbindelse NO305561B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITMI941696A IT1271689B (it) 1994-08-04 1994-08-04 8-fluoro-antracicline, loro processi di preparazione e composizioni farmaceutiche che le contengono
PCT/EP1995/003061 WO1996004292A1 (en) 1994-08-04 1995-08-01 8-fluoro-anthracyclines, processes for their preparation and pharmaceutical compositions containing them

Publications (3)

Publication Number Publication Date
NO970059D0 NO970059D0 (no) 1997-01-08
NO970059L true NO970059L (no) 1997-01-08
NO305561B1 NO305561B1 (no) 1999-06-21

Family

ID=11369446

Family Applications (1)

Application Number Title Priority Date Filing Date
NO970059A NO305561B1 (no) 1994-08-04 1997-01-08 Antrasyklinforbindelse

Country Status (25)

Country Link
US (1) US5814608A (no)
EP (1) EP0776328B1 (no)
JP (1) JPH10503509A (no)
AT (1) ATE172980T1 (no)
AU (1) AU700929B2 (no)
BG (1) BG101163A (no)
BR (1) BR9508518A (no)
CA (1) CA2196752A1 (no)
CZ (1) CZ28097A3 (no)
DE (1) DE69505828T2 (no)
DK (1) DK0776328T3 (no)
ES (1) ES2126923T3 (no)
FI (1) FI970455A0 (no)
HR (1) HRP950436A2 (no)
HU (1) HUT76339A (no)
IL (1) IL114791A0 (no)
IT (1) IT1271689B (no)
NO (1) NO305561B1 (no)
NZ (1) NZ291426A (no)
PL (1) PL319630A1 (no)
RU (1) RU2146261C1 (no)
SK (1) SK13797A3 (no)
TJ (1) TJ245B (no)
WO (1) WO1996004292A1 (no)
ZA (1) ZA956480B (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999058543A1 (en) * 1998-05-13 1999-11-18 Instytut Farmaceutyczny New n-alkyloxycarbonyl derivatives of monosaccharides l-acosamine and l-daunosamine
RU2450013C2 (ru) * 2005-12-13 2012-05-10 Солюкс Корпорейшен Способ получения 4-деметилдаунорубицина
US8802830B2 (en) * 2005-12-20 2014-08-12 Solux Corporation Synthesis of epirubicin from 13-dihydrodaunorubicine
US8357785B2 (en) * 2008-01-08 2013-01-22 Solux Corporation Method of aralkylation of 4′-hydroxyl group of anthracylins
RU2642068C1 (ru) * 2017-04-26 2018-01-24 Федеральное государственное бюджетное учреждение науки Институт элементоорганических соединений им. А.Н. Несмеянова Российской академии наук (ИНЭОС РАН) N-пиперонильные производные даунорубицина, обладающие антипролиферативными свойствами

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA21995A1 (fr) * 1989-11-13 1991-07-01 Menarini Farma Ind Nouvelles fluoronaphthacenediones,leurs derives glycozyles et leurs procedes de fabrication .
IT1241927B (it) * 1990-05-14 1994-02-01 Menarini Farma Ind 3'-deamino-4'-deossi-4'-amino-8-fluoroantra- cicline processi per la loro preparazione e composizioni farmaceutiche che le contengono
JPH06504034A (ja) * 1990-06-11 1994-05-12 バイオケム　ファーマ　インコーポレイテッド 複素環式アントラサイクリオンならびにアントラサイクリン類似化合物
IT1262565B (it) * 1993-09-30 1996-07-04 Menarini Farma Ind Disaccaridi di antracicline, loro processi di preparazione e composizioni farmaceutiche che li contengono.

Also Published As

Publication number Publication date
TJ245B (en) 2001-08-06
SK13797A3 (en) 1997-07-09
NZ291426A (en) 1998-05-27
EP0776328A1 (en) 1997-06-04
ITMI941696A1 (it) 1996-02-04
HRP950436A2 (en) 1997-10-31
IT1271689B (it) 1997-06-04
ES2126923T3 (es) 1999-04-01
DE69505828T2 (de) 1999-05-20
FI970455A (fi) 1997-02-03
US5814608A (en) 1998-09-29
DE69505828D1 (de) 1998-12-10
NO305561B1 (no) 1999-06-21
EP0776328B1 (en) 1998-11-04
FI970455A0 (fi) 1997-02-03
NO970059D0 (no) 1997-01-08
AU3255395A (en) 1996-03-04
PL319630A1 (en) 1997-08-18
DK0776328T3 (da) 1999-07-19
ITMI941696A0 (it) 1994-08-04
JPH10503509A (ja) 1998-03-31
ATE172980T1 (de) 1998-11-15
WO1996004292A1 (en) 1996-02-15
CA2196752A1 (en) 1996-02-15
RU2146261C1 (ru) 2000-03-10
BR9508518A (pt) 1997-12-23
ZA956480B (en) 1996-03-14
BG101163A (en) 1997-09-30
AU700929B2 (en) 1999-01-14
IL114791A0 (en) 1995-11-27
CZ28097A3 (en) 1997-08-13
HUT76339A (en) 1997-08-28

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