NO964485L - Fremgangsmåte for stabilisering av forbindelsen DX-52-1 og lyofilisert sammensetning derav - Google Patents

Fremgangsmåte for stabilisering av forbindelsen DX-52-1 og lyofilisert sammensetning derav

Info

Publication number
NO964485L
NO964485L NO964485A NO964485A NO964485L NO 964485 L NO964485 L NO 964485L NO 964485 A NO964485 A NO 964485A NO 964485 A NO964485 A NO 964485A NO 964485 L NO964485 L NO 964485L
Authority
NO
Norway
Prior art keywords
lyophilized composition
stabilizing compound
composition
stabilizing
compound
Prior art date
Application number
NO964485A
Other languages
English (en)
Other versions
NO964485D0 (no
Inventor
Masashi Nakakura
Eiji Hayakawa
Tokuyuki Kuroda
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Publication of NO964485D0 publication Critical patent/NO964485D0/no
Publication of NO964485L publication Critical patent/NO964485L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

En lagringsstabil dessikert sammensetning er dannet av et DX-52-1 derivat ifølge formel (I) og minst et sakkarid. Sammensetningen kan bli dannet ved lyofilisering av en sammensetning som fortrinnsvis har en pH på 7-12.
NO964485A 1994-04-25 1996-10-22 Fremgangsmåte for stabilisering av forbindelsen DX-52-1 og lyofilisert sammensetning derav NO964485L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP8633794 1994-04-25
PCT/JP1995/000792 WO1995029178A1 (en) 1994-04-25 1995-04-21 Method for stabilizing compound dx-52-1 and lyophilized composition thereof

Publications (2)

Publication Number Publication Date
NO964485D0 NO964485D0 (no) 1996-10-22
NO964485L true NO964485L (no) 1996-10-22

Family

ID=13884042

Family Applications (1)

Application Number Title Priority Date Filing Date
NO964485A NO964485L (no) 1994-04-25 1996-10-22 Fremgangsmåte for stabilisering av forbindelsen DX-52-1 og lyofilisert sammensetning derav

Country Status (12)

Country Link
US (1) US5977109A (no)
EP (1) EP0757688A1 (no)
JP (1) JPH10502616A (no)
CN (1) CN1046516C (no)
AU (1) AU685264B2 (no)
CA (1) CA2188682A1 (no)
FI (1) FI964271A (no)
HU (1) HUT75780A (no)
NO (1) NO964485L (no)
NZ (1) NZ284154A (no)
PL (1) PL316995A1 (no)
WO (1) WO1995029178A1 (no)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI334866B (en) * 2002-05-29 2010-12-21 Mercian Corp Novel physiologically active substances
KR101307999B1 (ko) 2004-12-01 2013-09-12 니폰 조키 세야쿠 가부시키가이샤 건조물 및 그 제조방법
JPWO2008020584A1 (ja) * 2006-08-14 2010-01-07 エーザイ・アール・アンド・ディー・マネジメント株式会社 安定な凍結乾燥製剤
US10004703B2 (en) 2006-10-12 2018-06-26 Biogen Chesapeake Llc Treatment of alzheimer's disease using compounds that reduce the activity of non-selective CA++ activated ATP-sensitive cation channels regulated by SUR1 channels
WO2008046014A1 (en) 2006-10-12 2008-04-17 Remedy Pharmaceuticals, Inc. Treatment of alzheimer's disease using compounds that reduce the activity of non-selective ca++- activated atp-sensitive cation channels regulated by sur1 receptors
JP2010006704A (ja) * 2006-11-07 2010-01-14 Nippon Kayaku Co Ltd フェナンスリジン誘導体の凍結乾燥製剤
KR20090104002A (ko) 2007-01-29 2009-10-05 에자이 알앤드디 매니지먼트 가부시키가이샤 매크롤라이드계 화합물의 고체, 그의 제조 방법 및 그의 의약 조성물
PT2868315T (pt) * 2007-12-04 2017-09-04 Remedy Pharmaceuticals Inc Formulações melhoradas e métodos para liofilização e liofilizados assim produzidos
US20110034560A1 (en) 2008-01-29 2011-02-10 Sven Jacobson Liquid formulations of compounds active at sulfonylurea receptors
CN102297962B (zh) * 2011-05-23 2014-01-08 董理 一种检测碱性磷酸酶的试剂盒
GB201804835D0 (en) * 2018-03-26 2018-05-09 Ge Healthcare As Formulation and method of preparation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0108817A1 (en) * 1982-11-06 1984-05-23 Kanegafuchi Chemical Industry Co., Ltd. Stable composition of S-adenosyl-L-methionine and process for preparation thereof
JPS59210086A (ja) * 1983-05-13 1984-11-28 Kyowa Hakko Kogyo Co Ltd Ｄｘ―５２―１類及びその塩類

Also Published As

Publication number Publication date
NZ284154A (en) 1997-11-24
CN1046516C (zh) 1999-11-17
EP0757688A1 (en) 1997-02-12
NO964485D0 (no) 1996-10-22
US5977109A (en) 1999-11-02
FI964271A0 (fi) 1996-10-23
CA2188682A1 (en) 1995-11-02
FI964271A (fi) 1996-10-23
AU685264B2 (en) 1998-01-15
CN1146769A (zh) 1997-04-02
HU9602935D0 (en) 1996-12-30
HUT75780A (en) 1997-05-28
PL316995A1 (en) 1997-03-03
AU2267595A (en) 1995-11-16
WO1995029178A1 (en) 1995-11-02
JPH10502616A (ja) 1998-03-10

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