ATE169023T1 - 2-spirocyclopropyl 4-acylcephalosporine und verfahren zu ihrer herstellung - Google Patents
2-spirocyclopropyl 4-acylcephalosporine und verfahren zu ihrer herstellungInfo
- Publication number
- ATE169023T1 ATE169023T1 AT92907957T AT92907957T ATE169023T1 AT E169023 T1 ATE169023 T1 AT E169023T1 AT 92907957 T AT92907957 T AT 92907957T AT 92907957 T AT92907957 T AT 92907957T AT E169023 T1 ATE169023 T1 AT E169023T1
- Authority
- AT
- Austria
- Prior art keywords
- spirocyclopropyl
- acylcephalosporins
- production
- useful
- acylcephem
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Detergent Compositions (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/681,680 US5258377A (en) | 1991-04-08 | 1991-04-08 | 2-spirocyclopropyl 4-acylcephems |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE169023T1 true ATE169023T1 (de) | 1998-08-15 |
Family
ID=24736298
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT92907957T ATE169023T1 (de) | 1991-04-08 | 1992-04-07 | 2-spirocyclopropyl 4-acylcephalosporine und verfahren zu ihrer herstellung |
Country Status (10)
Country | Link |
---|---|
US (1) | US5258377A (de) |
EP (1) | EP0580650B1 (de) |
JP (1) | JPH06506207A (de) |
AT (1) | ATE169023T1 (de) |
CA (1) | CA2107892A1 (de) |
DE (1) | DE69226432D1 (de) |
FI (1) | FI934395A (de) |
HU (1) | HUT66046A (de) |
WO (1) | WO1992017482A1 (de) |
ZA (1) | ZA922504B (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8811388D0 (en) * | 1988-05-13 | 1988-06-15 | Erba Carlo Spa | 1,1-dioxo-cephem-4-carbothiolic acid derivatives |
GB8928373D0 (en) * | 1989-12-15 | 1990-02-21 | Erba Carlo Spa | Beta-lactam derivatives |
US5439904A (en) * | 1993-12-07 | 1995-08-08 | Synphar Laboratories, Inc. | 2-spiro(2'-spirocycloalkyl)cyclopropyl cephalosporin sulfones as antiinflammatory and antigenerative agents |
US5597817A (en) * | 1994-12-09 | 1997-01-28 | Southern Methodist University | 7-vinylidene cephalosporins and methods of using the same |
US5629306A (en) | 1994-12-09 | 1997-05-13 | Research Corporation Technologies, Inc. | 7-alkylidene cephalosporanic acid derivatives and methods of using the same |
US5760027A (en) * | 1996-12-06 | 1998-06-02 | Research Corporation Technologies, Inc. | Use of 7-alkylidene cephalosporins to inhibit elastase activity |
US6407091B1 (en) * | 1999-04-15 | 2002-06-18 | Research Corporation Technologies, Inc. | β-lactamase inhibiting compounds |
EP1660506A4 (de) * | 2003-08-25 | 2009-02-25 | Revaax Pharmaceuticals Llc | Orale neurotherapeutische cefazolinzusammensetzungen |
AR112480A1 (es) | 2017-08-24 | 2019-10-30 | Novo Nordisk As | Composiciones de glp-1 y sus usos |
US20230093542A1 (en) | 2020-02-18 | 2023-03-23 | Novo Nordisk A/S | Glp-1 compositions and uses thereof |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH563396A5 (de) * | 1970-06-05 | 1975-06-30 | Ciba Geigy Ag | |
US4547371A (en) * | 1983-04-18 | 1985-10-15 | Merck & Co., Inc. | Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents |
EP0124081A3 (de) * | 1983-05-02 | 1986-11-26 | Merck & Co. Inc. | Substituierte Cephalosporinsulfone mit Antientzündungs- und Antidegenerativwirkung, sie enthaltende Zusammensetzungen und Verfahren zur Herstellung |
US4717722A (en) * | 1984-05-07 | 1988-01-05 | Merck & Co., Inc. | Substituted 1-oxa-dethiacephalosporins as anti-inflammatory and antidegenerative agents |
DE3751700D1 (de) * | 1986-11-12 | 1996-03-21 | Merck & Co Inc | Substituierte Cephalosporinsulfone als anti-entzündliche und anti-degenerative Mittel |
JPH01226887A (ja) * | 1988-03-07 | 1989-09-11 | Takeda Chem Ind Ltd | 3環性セファムまたはイソセファム化合物,その製造法およびエラスターゼ阻害剤 |
GB8808701D0 (en) * | 1988-04-13 | 1988-05-18 | Erba Carlo Spa | Beta-lactam derivatives |
GB8811388D0 (en) * | 1988-05-13 | 1988-06-15 | Erba Carlo Spa | 1,1-dioxo-cephem-4-carbothiolic acid derivatives |
KR927003605A (ko) * | 1989-10-06 | 1992-12-18 | 산파아 레버러토리즈, 인크. | 신규한 2-스피로사이클로프로필세파로스포린설폰유도체 및 이의 제조방법 |
-
1991
- 1991-04-08 US US07/681,680 patent/US5258377A/en not_active Expired - Fee Related
-
1992
- 1992-04-07 HU HU9302717A patent/HUT66046A/hu unknown
- 1992-04-07 ZA ZA922504A patent/ZA922504B/xx unknown
- 1992-04-07 JP JP4507471A patent/JPH06506207A/ja active Pending
- 1992-04-07 CA CA002107892A patent/CA2107892A1/en not_active Abandoned
- 1992-04-07 EP EP92907957A patent/EP0580650B1/de not_active Expired - Lifetime
- 1992-04-07 DE DE69226432T patent/DE69226432D1/de not_active Expired - Lifetime
- 1992-04-07 WO PCT/CA1992/000145 patent/WO1992017482A1/en active IP Right Grant
- 1992-04-07 AT AT92907957T patent/ATE169023T1/de not_active IP Right Cessation
-
1993
- 1993-10-06 FI FI934395A patent/FI934395A/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
ZA922504B (en) | 1993-12-07 |
WO1992017482A1 (en) | 1992-10-15 |
US5258377A (en) | 1993-11-02 |
CA2107892A1 (en) | 1992-10-09 |
FI934395A0 (fi) | 1993-10-06 |
JPH06506207A (ja) | 1994-07-14 |
DE69226432D1 (de) | 1998-09-03 |
AU668503B2 (en) | 1996-05-09 |
HU9302717D0 (en) | 1993-12-28 |
EP0580650A1 (de) | 1994-02-02 |
FI934395A (fi) | 1993-10-21 |
EP0580650B1 (de) | 1998-07-29 |
AU1556092A (en) | 1992-11-02 |
HUT66046A (en) | 1994-09-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |