FI934395A - 2-spirocyklopropyl 4-acylcephemi samt foerfarande foer framstaellning daerav - Google Patents

2-spirocyklopropyl 4-acylcephemi samt foerfarande foer framstaellning daerav Download PDF

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Publication number
FI934395A
FI934395A FI934395A FI934395A FI934395A FI 934395 A FI934395 A FI 934395A FI 934395 A FI934395 A FI 934395A FI 934395 A FI934395 A FI 934395A FI 934395 A FI934395 A FI 934395A
Authority
FI
Finland
Prior art keywords
spyrocyklopropyl
acylcephemi
foerfarande foer
foer framstaellning
samt foerfarande
Prior art date
Application number
FI934395A
Other languages
English (en)
Other versions
FI934395A0 (fi
Inventor
Samarendra N Maiti
Narender A V Reddy
David Czajowski
Paul Spevak
Charles Fiakpui
Roland G Micetich
Original Assignee
Synphar Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synphar Lab Inc filed Critical Synphar Lab Inc
Publication of FI934395A0 publication Critical patent/FI934395A0/fi
Publication of FI934395A publication Critical patent/FI934395A/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/06Antigout agents, e.g. antihyperuricemic or uricosuric agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Detergent Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI934395A 1991-04-08 1993-10-06 2-spirocyklopropyl 4-acylcephemi samt foerfarande foer framstaellning daerav FI934395A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/681,680 US5258377A (en) 1991-04-08 1991-04-08 2-spirocyclopropyl 4-acylcephems
PCT/CA1992/000145 WO1992017482A1 (en) 1991-04-08 1992-04-07 Novel 2-spirocyclopropyl 4-acylcephems and processes for the preparation thereof

Publications (2)

Publication Number Publication Date
FI934395A0 FI934395A0 (fi) 1993-10-06
FI934395A true FI934395A (fi) 1993-10-21

Family

ID=24736298

Family Applications (1)

Application Number Title Priority Date Filing Date
FI934395A FI934395A (fi) 1991-04-08 1993-10-06 2-spirocyklopropyl 4-acylcephemi samt foerfarande foer framstaellning daerav

Country Status (10)

Country Link
US (1) US5258377A (fi)
EP (1) EP0580650B1 (fi)
JP (1) JPH06506207A (fi)
AT (1) ATE169023T1 (fi)
CA (1) CA2107892A1 (fi)
DE (1) DE69226432D1 (fi)
FI (1) FI934395A (fi)
HU (1) HUT66046A (fi)
WO (1) WO1992017482A1 (fi)
ZA (1) ZA922504B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8811388D0 (en) * 1988-05-13 1988-06-15 Erba Carlo Spa 1,1-dioxo-cephem-4-carbothiolic acid derivatives
GB8928373D0 (en) * 1989-12-15 1990-02-21 Erba Carlo Spa Beta-lactam derivatives
US5439904A (en) * 1993-12-07 1995-08-08 Synphar Laboratories, Inc. 2-spiro(2'-spirocycloalkyl)cyclopropyl cephalosporin sulfones as antiinflammatory and antigenerative agents
US5629306A (en) 1994-12-09 1997-05-13 Research Corporation Technologies, Inc. 7-alkylidene cephalosporanic acid derivatives and methods of using the same
US5597817A (en) * 1994-12-09 1997-01-28 Southern Methodist University 7-vinylidene cephalosporins and methods of using the same
US5760027A (en) * 1996-12-06 1998-06-02 Research Corporation Technologies, Inc. Use of 7-alkylidene cephalosporins to inhibit elastase activity
US6407091B1 (en) * 1999-04-15 2002-06-18 Research Corporation Technologies, Inc. β-lactamase inhibiting compounds
BRPI0413908A (pt) * 2003-08-25 2006-10-24 Revaax Pharmaceuticals Llc formulação farmacêutica neuroterapêutica em forma de dosagem oral, composto, e, método de tratamento de um distúrbio comportamental ou um distúrbio cognitivo
PL3474820T3 (pl) 2017-08-24 2024-05-13 Novo Nordisk A/S Kompozycje glp-1 i ich zastosowania
CA3165359A1 (en) 2020-02-18 2021-07-22 Dorthe Kot Engelund Glp-1 compositions and uses thereof

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH563396A5 (fi) * 1970-06-05 1975-06-30 Ciba Geigy Ag
US4547371A (en) * 1983-04-18 1985-10-15 Merck & Co., Inc. Substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents
EP0124081A3 (en) * 1983-05-02 1986-11-26 Merck & Co. Inc. New substituted cephalosporin sulfones as antiinflammatory and antidegenerative agents, pharmaceutical compositions containing the same and processes for making them
US4717722A (en) * 1984-05-07 1988-01-05 Merck & Co., Inc. Substituted 1-oxa-dethiacephalosporins as anti-inflammatory and antidegenerative agents
EP0267723B1 (en) * 1986-11-12 1996-02-07 Merck & Co. Inc. New substituted cephalosporin sulfones as anti-inflammatory and anti-degenerative agents
JPH01226887A (ja) * 1988-03-07 1989-09-11 Takeda Chem Ind Ltd 3環性セファムまたはイソセファム化合物,その製造法およびエラスターゼ阻害剤
GB8808701D0 (en) * 1988-04-13 1988-05-18 Erba Carlo Spa Beta-lactam derivatives
GB8811388D0 (en) * 1988-05-13 1988-06-15 Erba Carlo Spa 1,1-dioxo-cephem-4-carbothiolic acid derivatives
DE69032857T2 (de) * 1989-10-06 1999-08-05 Synphar Laboratories Inc., Edmonton, Alberta 2-spirocyclopropylcephalosporinderivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
ATE169023T1 (de) 1998-08-15
AU1556092A (en) 1992-11-02
WO1992017482A1 (en) 1992-10-15
HUT66046A (en) 1994-09-28
EP0580650A1 (en) 1994-02-02
CA2107892A1 (en) 1992-10-09
JPH06506207A (ja) 1994-07-14
ZA922504B (en) 1993-12-07
FI934395A0 (fi) 1993-10-06
US5258377A (en) 1993-11-02
AU668503B2 (en) 1996-05-09
HU9302717D0 (en) 1993-12-28
DE69226432D1 (de) 1998-09-03
EP0580650B1 (en) 1998-07-29

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