NO962303D0 - Mutanter av benmorfogene proteiner - Google Patents

Mutanter av benmorfogene proteiner

Info

Publication number
NO962303D0
NO962303D0 NO962303A NO962303A NO962303D0 NO 962303 D0 NO962303 D0 NO 962303D0 NO 962303 A NO962303 A NO 962303A NO 962303 A NO962303 A NO 962303A NO 962303 D0 NO962303 D0 NO 962303D0
Authority
NO
Norway
Prior art keywords
mutants
bmp
bone morphogenic
morphogenic proteins
disclosed
Prior art date
Application number
NO962303A
Other languages
English (en)
Other versions
NO317800B1 (no
NO962303L (no
Inventor
Neil M Wolfman
John Mccoy
Original Assignee
Genetics Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst filed Critical Genetics Inst
Publication of NO962303D0 publication Critical patent/NO962303D0/no
Publication of NO962303L publication Critical patent/NO962303L/no
Publication of NO317800B1 publication Critical patent/NO317800B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO19962303A 1993-12-07 1996-06-04 Rekombinante DNA-molekyler som koder for benmorfogene proteiner og rensede sammensetninger og fremgangsmater derav. NO317800B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/163,877 US5399677A (en) 1993-12-07 1993-12-07 Mutants of bone morphogenetic proteins
PCT/US1994/013181 WO1995016034A1 (en) 1993-12-07 1994-11-15 Mutants of bone morphogenetic proteins

Publications (3)

Publication Number Publication Date
NO962303D0 true NO962303D0 (no) 1996-06-04
NO962303L NO962303L (no) 1996-06-04
NO317800B1 NO317800B1 (no) 2004-12-13

Family

ID=22591964

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19962303A NO317800B1 (no) 1993-12-07 1996-06-04 Rekombinante DNA-molekyler som koder for benmorfogene proteiner og rensede sammensetninger og fremgangsmater derav.

Country Status (16)

Country Link
US (3) US5399677A (no)
EP (1) EP0733108B1 (no)
JP (1) JP3704350B2 (no)
KR (1) KR100361058B1 (no)
AT (1) ATE200515T1 (no)
AU (1) AU682238B2 (no)
CA (1) CA2176943C (no)
DE (1) DE69427093T2 (no)
DK (1) DK0733108T3 (no)
ES (1) ES2157313T3 (no)
FI (1) FI118428B (no)
GR (1) GR3035769T3 (no)
NO (1) NO317800B1 (no)
OA (1) OA10294A (no)
PT (1) PT733108E (no)
WO (1) WO1995016034A1 (no)

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US7235527B2 (en) 1995-04-19 2007-06-26 Biopharm Gesellschaft Zur Biotechnologieschen Entwicklung Von Pharmaka Mbh Protein and process for producing the same
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CA2531969C (en) * 2003-07-09 2011-04-26 National Institute Of Advanced Industrial Science And Technology Protein-refolding material
PL1675608T3 (pl) * 2003-09-12 2007-11-30 Wyeth Corp Stałe fosforanowo wapniowe pałeczki do wstrzyknięć dla dostarczania białek osteogennych
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US20070066525A1 (en) * 2004-02-04 2007-03-22 Lee John C Compositions and therapeutic methods using morphogenic proteins
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JP2008534607A (ja) * 2005-03-30 2008-08-28 ワイス Ｂｍｐを投与することによって毛髪の成長を刺激するための方法
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EP1885751B1 (en) 2005-05-27 2011-11-16 BBS - Bioactive Bone Substitutes Oy Bone morphogenetic protein 6 containing a heparin binding site and osteogenic devices and pharmaceutical products containing thereof
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CL2008000883A1 (es) * 2007-03-28 2008-10-03 Wyeth6 3 Metodo de deteccion de compuestos capaces de antagonizar la senalizacion de il-17f/il-17a; compuesto identificado por dicho metodo; uso de una cantidad de un antagonista de senalizacion de il-17f/il-17a, composicion farmaceutica que comprende dicho a
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EP2019117A1 (en) * 2007-07-27 2009-01-28 BIOPHARM GESELLSCHAFT ZUR BIOTECHNOLOGISCHEN ENTWICKLUNG VON PHARMAKA mbH Optimized purification process of recombinant growth factor protein
EP2188371B1 (en) * 2007-08-09 2017-12-20 Wyeth LLC Use of perfusion to enhance production of fed-batch cell culture in bioreactors
EP2350130B1 (en) * 2008-10-31 2018-10-03 Wyeth LLC Purification of acidic proteins using ceramic hydroxyapatite chromatography
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Also Published As

Publication number Publication date
PT733108E (pt) 2001-08-30
FI962349A (fi) 1996-07-16
GR3035769T3 (en) 2001-07-31
EP0733108A1 (en) 1996-09-25
NO317800B1 (no) 2004-12-13
JPH09506259A (ja) 1997-06-24
US5804416A (en) 1998-09-08
AU682238B2 (en) 1997-09-25
OA10294A (en) 1997-10-07
US5399677A (en) 1995-03-21
AU1209395A (en) 1995-06-27
JP3704350B2 (ja) 2005-10-12
US5756308A (en) 1998-05-26
WO1995016034A1 (en) 1995-06-15
CA2176943C (en) 2007-04-03
DE69427093D1 (de) 2001-05-17
ATE200515T1 (de) 2001-04-15
KR100361058B1 (ko) 2003-04-10
DK0733108T3 (da) 2001-06-18
FI962349A0 (fi) 1996-06-06
DE69427093T2 (de) 2001-11-15
FI118428B (fi) 2007-11-15
EP0733108B1 (en) 2001-04-11
NO962303L (no) 1996-06-04
CA2176943A1 (en) 1995-06-15
ES2157313T3 (es) 2001-08-16
KR960706558A (ko) 1996-12-09

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