ATE259652T1 - Neuronale verwendungen des bmp-11 - Google Patents
Neuronale verwendungen des bmp-11Info
- Publication number
- ATE259652T1 ATE259652T1 AT98957711T AT98957711T ATE259652T1 AT E259652 T1 ATE259652 T1 AT E259652T1 AT 98957711 T AT98957711 T AT 98957711T AT 98957711 T AT98957711 T AT 98957711T AT E259652 T1 ATE259652 T1 AT E259652T1
- Authority
- AT
- Austria
- Prior art keywords
- proteins
- bmp
- useful
- disclosed
- neural
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0619—Neurons
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/10—Growth factors
- C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US96629797A | 1997-11-07 | 1997-11-07 | |
PCT/US1998/023827 WO1999024058A2 (en) | 1997-11-07 | 1998-11-06 | Neuronal uses of bmp-11 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE259652T1 true ATE259652T1 (de) | 2004-03-15 |
Family
ID=25511184
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT98957711T ATE259652T1 (de) | 1997-11-07 | 1998-11-06 | Neuronale verwendungen des bmp-11 |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1028744B1 (de) |
JP (1) | JP2001522810A (de) |
AT (1) | ATE259652T1 (de) |
AU (2) | AU1276399A (de) |
CA (1) | CA2309538A1 (de) |
DE (1) | DE69821793T2 (de) |
DK (1) | DK1028744T3 (de) |
ES (1) | ES2213927T3 (de) |
PT (1) | PT1028744E (de) |
WO (2) | WO1999024057A2 (de) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030104977A1 (en) * | 2000-03-31 | 2003-06-05 | Ugo Ripamonti | Methods for inducing angiogenesis using morphogenic proteins and stimulatory factors |
TWI329129B (en) | 2001-02-08 | 2010-08-21 | Wyeth Corp | Modified and stabilized gdf propeptides and uses thereof |
EP1406926A2 (de) * | 2001-07-06 | 2004-04-14 | Nsgene A/S | Neue neurotrophe faktoren |
US7320789B2 (en) | 2001-09-26 | 2008-01-22 | Wyeth | Antibody inhibitors of GDF-8 and uses thereof |
JP4429729B2 (ja) | 2002-02-21 | 2010-03-10 | ワイス エルエルシー | Gasp1;フォリスタチンドメイン含有タンパク質 |
WO2003072714A2 (en) | 2002-02-21 | 2003-09-04 | Wyeth | Follistatin domain containing proteins |
US7261893B2 (en) | 2002-10-22 | 2007-08-28 | Wyeth | Neutralizing antibodies against GDF-8 and uses therefor |
US7591999B2 (en) | 2003-03-04 | 2009-09-22 | Mitsubishi Tanabe Pharma Corporation | Powdery preparation for nasal administration |
EP1635870A2 (de) | 2003-06-02 | 2006-03-22 | Wyeth | Verwendung von myostatin (gdf8) inhibitoren in kombination mit kortikosteroiden zur behandlung neuromuskulärer erkrankungen |
EP1951756B1 (de) | 2005-10-06 | 2015-01-07 | Eli Lilly And Company | Anti-myostatin-antikörper |
UA92504C2 (en) | 2005-10-12 | 2010-11-10 | Эли Лилли Энд Компани | Anti-myostatin monoclonal antibody |
PT2066695E (pt) | 2006-09-05 | 2013-05-23 | Lilly Co Eli | Anticorpos anti-miostatina |
EP4140497A1 (de) | 2013-04-08 | 2023-03-01 | President and Fellows of Harvard College | Zusammensetzungen zum verjüngen von stammzellen der skelettmuskulatur |
US20160220640A1 (en) * | 2013-06-11 | 2016-08-04 | The Brigham And Women's Hospital, Inc. | Methods and compositions for increasing neurogenesis and angiogenesis |
WO2015070076A2 (en) * | 2013-11-08 | 2015-05-14 | President And Fellows Of Harvard College | Methods and compositions for rejuvenating neuromuscular junctions |
IL301476A (en) | 2016-01-06 | 2023-05-01 | Harvard College | Treatment with GDF11 prevents weight gain, improves glucose loading and reduces hepatosteatosis |
WO2019144053A1 (en) * | 2018-01-19 | 2019-07-25 | President And Fellows Of Harward College | Gdf11 variants and uses thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2161808C (en) * | 1993-05-12 | 2008-08-05 | Anthony J. Celeste | Bmp-11 compositions |
SE9302550D0 (sv) * | 1993-07-30 | 1993-07-30 | Ernst Hoerlin | Powder inhaler |
PT716610E (pt) * | 1993-08-26 | 2006-08-31 | Genetics Inst Llc | Proteinas morfogeneticas dos ossos de seres humanos para utilizacao em regeneracao neural |
ES2251721T3 (es) * | 1994-07-08 | 2006-05-01 | The Johns Hopkins University School Of Medicine | Factor-11 de diferenciacion del crecimiento. |
-
1998
- 1998-10-23 AU AU12763/99A patent/AU1276399A/en not_active Withdrawn
- 1998-10-23 WO PCT/US1998/022574 patent/WO1999024057A2/en not_active Application Discontinuation
- 1998-11-06 DK DK98957711T patent/DK1028744T3/da active
- 1998-11-06 ES ES98957711T patent/ES2213927T3/es not_active Expired - Lifetime
- 1998-11-06 CA CA002309538A patent/CA2309538A1/en not_active Abandoned
- 1998-11-06 PT PT98957711T patent/PT1028744E/pt unknown
- 1998-11-06 JP JP2000520146A patent/JP2001522810A/ja active Pending
- 1998-11-06 WO PCT/US1998/023827 patent/WO1999024058A2/en active IP Right Grant
- 1998-11-06 AU AU13900/99A patent/AU761940B2/en not_active Ceased
- 1998-11-06 DE DE69821793T patent/DE69821793T2/de not_active Expired - Lifetime
- 1998-11-06 AT AT98957711T patent/ATE259652T1/de active
- 1998-11-06 EP EP98957711A patent/EP1028744B1/de not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69821793T2 (de) | 2004-12-30 |
DE69821793D1 (de) | 2004-03-25 |
ES2213927T3 (es) | 2004-09-01 |
AU761940B2 (en) | 2003-06-12 |
DK1028744T3 (da) | 2004-06-21 |
EP1028744B1 (de) | 2004-02-18 |
AU1390099A (en) | 1999-05-31 |
EP1028744A2 (de) | 2000-08-23 |
WO1999024057A2 (en) | 1999-05-20 |
WO1999024058A3 (en) | 1999-08-19 |
AU1276399A (en) | 1999-05-31 |
CA2309538A1 (en) | 1999-05-20 |
WO1999024058A2 (en) | 1999-05-20 |
JP2001522810A (ja) | 2001-11-20 |
PT1028744E (pt) | 2004-06-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE69434875D1 (de) | BMP-11 Zusammenstellungen | |
ATE259652T1 (de) | Neuronale verwendungen des bmp-11 | |
ATE265529T1 (de) | Bmp-10 zusammensetzungen | |
DK0429570T3 (da) | Osteoinducerende præparater | |
ATE328896T1 (de) | Faktor viii vom schwein und hybriden | |
CA2265508A1 (en) | Bone morphogenetic protein-16 (bmp-16) compositions | |
EE04221B1 (et) | Östrogeeni kasutamine ravimi valmistamiseks füüsiliste seisundite raviks menopausijärgsetel isikutel | |
IL192078A0 (en) | Recombinant ??-l-iduronidase,methods for producing and purifying the same and methods for treating diseases caused by deficiencies thereof | |
DE69726884D1 (de) | Menschliches sdf-5 protein und diesbezügliche zusammensetzungen | |
EP1420031A3 (de) | Morphogenetisches Protein der Knochen, BMP-18, und deren Zusammensetzungen | |
DE69728415D1 (de) | Produkte des keratinocyten-wachstumsfaktors 2 (kgf-2) | |
GR3033698T3 (en) | Use of a hymenoptera venom for the manufacture of a medicament for treating dna virus infections. | |
NZ334762A (en) | Human DNase I variants having binding affinity to actin | |
ATE349521T1 (de) | Mit cd40 und traf interagierende proteine | |
MXPA02000801A (es) | Homologo humano de polinucleotidos, nesp55 de proteina secretora de neuroendocrino bovino y usos el mismo relacionado con la obesidad. | |
ATE245438T1 (de) | Verwendung von oligomerem matrixprotein aus knorpel zur behandlung von rheumatoider arthritis | |
DE69910608D1 (de) | Neue therapeutische verwendung von 1,6-dimethyl-8beta-hydroxymethyl-10alpha-methoxyergolin | |
MX9800507A (es) | Ctla-8 humana y usos de proteinas relacionadas con la ctla-8. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1028744 Country of ref document: EP |