NO960270D0 - Nye 1,4-(difenylalkyl)piperazin derivater - Google Patents

Nye 1,4-(difenylalkyl)piperazin derivater

Info

Publication number
NO960270D0
NO960270D0 NO960270A NO960270A NO960270D0 NO 960270 D0 NO960270 D0 NO 960270D0 NO 960270 A NO960270 A NO 960270A NO 960270 A NO960270 A NO 960270A NO 960270 D0 NO960270 D0 NO 960270D0
Authority
NO
Norway
Prior art keywords
diphenylalkyl
new
different
same
piperazine derivatives
Prior art date
Application number
NO960270A
Other languages
English (en)
Norwegian (no)
Other versions
NO960270L (no
Inventor
Yoichi Kawashima
Junzo Matsumoto
Kiyoshi Matsuno
Toshihiko Senda
Keiko Hirano
Original Assignee
Santen Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Santen Pharmaceutical Co Ltd filed Critical Santen Pharmaceutical Co Ltd
Publication of NO960270D0 publication Critical patent/NO960270D0/no
Publication of NO960270L publication Critical patent/NO960270L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO960270A 1993-07-28 1996-01-23 Nye 1,4-(difenylalkyl)piperazin derivater NO960270L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP18583993 1993-07-28
PCT/JP1994/001220 WO1995004050A1 (en) 1993-07-28 1994-07-25 Novel 1,4-di(phenylalkyl)piperazine derivative

Publications (2)

Publication Number Publication Date
NO960270D0 true NO960270D0 (no) 1996-01-23
NO960270L NO960270L (no) 1996-01-23

Family

ID=16177784

Family Applications (1)

Application Number Title Priority Date Filing Date
NO960270A NO960270L (no) 1993-07-28 1996-01-23 Nye 1,4-(difenylalkyl)piperazin derivater

Country Status (11)

Country Link
US (1) US5736546A (Direct)
EP (1) EP0711763B1 (Direct)
KR (1) KR100299734B1 (Direct)
CN (1) CN1042029C (Direct)
AT (1) ATE197047T1 (Direct)
CA (1) CA2168264A1 (Direct)
DE (1) DE69426157T2 (Direct)
ES (1) ES2151930T3 (Direct)
FI (1) FI960364A0 (Direct)
NO (1) NO960270L (Direct)
WO (1) WO1995004050A1 (Direct)

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US5859295A (en) * 1994-12-05 1999-01-12 University Of Kentucky Research Foundation Canavanine analogs and their use as chemotherapeutic agents
IL117149A0 (en) * 1995-02-23 1996-06-18 Schering Corp Muscarinic antagonists
US5889006A (en) * 1995-02-23 1999-03-30 Schering Corporation Muscarinic antagonists
HUP9601331A3 (en) * 1996-05-17 2000-06-28 Egyt Gyogyszervegyeszeti Gyar Piperazine- and homopiperazine-derivatives, process for producing them and pharmaceutical compositions containing them
DK0912515T3 (da) * 1996-07-10 2003-03-10 Schering Corp 1,4-Disubstituerede piperidiner som muscarinantagonister
US5952349A (en) * 1996-07-10 1999-09-14 Schering Corporation Muscarinic antagonists for treating memory loss
US5860391A (en) * 1996-08-06 1999-01-19 First Brands Corporation Absorbents containing activated carbons
US6713651B1 (en) * 1999-06-07 2004-03-30 Theravance, Inc. β2-adrenergic receptor agonists
KR100700347B1 (ko) 1998-11-09 2007-03-29 산텐 세이야꾸 가부시키가이샤 약물 의존증 치료제
AU5569800A (en) * 1999-06-30 2001-01-31 Santen Pharmaceutical Co. Ltd. Brain sigma-1 receptor-binding ligand
DE10050236A1 (de) * 2000-10-11 2002-04-25 Merck Patent Gmbh Verwendung bestimmter Substanzen, die an den Sigma-Rezeptor binden, zur Behandlung von Sarkomen und Karzinomen
CN1181065C (zh) * 2002-05-08 2004-12-22 上海医药工业研究院 芳烷甲酰烷基哌嗪衍生物及其作为脑神经保护剂的应用
CN1172919C (zh) 2002-06-03 2004-10-27 上海医药工业研究院 芳烷醇哌嗪衍生物及其在制备抗抑郁症药物中的应用
EP1635805A4 (en) * 2003-06-12 2007-08-08 Ms Science Corp SIGMA RECEPTOR LIGANDS FOR NEURONAL REGENERATION AND FUNCTIONAL RE-ESTABLISHMENT
WO2005028457A1 (en) * 2003-09-23 2005-03-31 Fermion Oy Preparation of quetiapine
DE102004061593A1 (de) * 2004-12-21 2006-06-22 Abbott Gmbh & Co. Kg Substituierte N-heterocyclische Verbindungen und ihre therapeutische Verwendung
CN101263127A (zh) * 2005-08-09 2008-09-10 株式会社爱慕知科学 哌嗪衍生物
CN101511187B (zh) * 2005-09-23 2012-07-04 株式会社爱慕知科学 哌啶和哌嗪衍生物
AU2006304787A1 (en) 2005-10-21 2007-04-26 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
EP2314289A1 (en) 2005-10-31 2011-04-27 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
WO2007089462A2 (en) * 2006-01-27 2007-08-09 M's Science Corporation Piperidine and piperazine derivatives
EP1988902B1 (en) * 2006-02-15 2011-11-23 M's Science Corporation Piperazine derivatives
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2021000A2 (en) 2006-05-09 2009-02-11 Braincells, Inc. Neurogenesis by modulating angiotensin
JP2009536667A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド ５ｈｔ受容体介在性の神経新生
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
WO2008060271A1 (en) * 2006-11-13 2008-05-22 M's Science Corporation Sigma ligands for neuronal regeneration and functional recovery
WO2009128057A2 (en) * 2008-04-18 2009-10-22 UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN et al Psycho-pharmaceuticals
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
US8673920B2 (en) * 2009-05-06 2014-03-18 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9073882B2 (en) 2010-10-27 2015-07-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9056859B2 (en) 2010-10-29 2015-06-16 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
RU2014110401A (ru) 2011-08-19 2015-09-27 Мерк Шарп И Доум Корп. Ингибиторы внешнего медуллярного калиевого канала почек
US9527830B2 (en) 2011-09-16 2016-12-27 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP2771005B1 (en) 2011-10-25 2016-05-18 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2013062900A1 (en) 2011-10-25 2013-05-02 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP2773206B1 (en) 2011-10-31 2018-02-21 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9139585B2 (en) 2011-10-31 2015-09-22 Merck Sharp & Dohme Corp. Inhibitors of the Renal Outer Medullary Potassium channel
US9493474B2 (en) 2011-10-31 2016-11-15 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP2790511B1 (en) 2011-12-16 2016-09-14 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
AR092031A1 (es) 2012-07-26 2015-03-18 Merck Sharp & Dohme Inhibidores del canal de potasio medular externo renal
EP2925322B1 (en) 2012-11-29 2018-10-24 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9573961B2 (en) 2012-12-19 2017-02-21 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2014126944A2 (en) 2013-02-18 2014-08-21 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
US9765074B2 (en) 2013-03-15 2017-09-19 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
EP3027625B1 (en) 2013-07-31 2018-05-30 Merck Sharp & Dohme Corp. Spiro-fused derivatives of piperidine useful for the treatment of inter alia hypertension and acute or chronic heart failure
WO2015065866A1 (en) 2013-10-31 2015-05-07 Merck Sharp & Dohme Corp. Inhibitors of the renal outer medullary potassium channel
WO2016127358A1 (en) 2015-02-12 2016-08-18 Merck Sharp & Dohme Corp. Inhibitors of renal outer medullary potassium channel

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Publication number Priority date Publication date Assignee Title
JPS5583771A (en) * 1978-12-20 1980-06-24 Kanebo Ltd N-substituted trimethoxybenzylpiperazine derivative and its acid addition salt
JPS60155171A (ja) * 1983-12-10 1985-08-15 Wako Pure Chem Ind Ltd ポリメトキシベンジルピペラジン誘導体
JPS6133827A (ja) * 1984-07-27 1986-02-17 Mitsubishi Electric Corp 放電加工装置
JP2722250B2 (ja) * 1989-05-30 1998-03-04 興和株式会社 新規なジアミン化合物及びこれを含有する脳機能障害改善剤
JPH05503517A (ja) * 1989-12-18 1993-06-10 バージニア・コモンウェルス・ユニバーシティ シグマレセプターリガンド及びその用途
EP0566189A1 (en) * 1992-04-13 1993-10-20 Akzo N.V. Psychotropic piperazine derivative
US5428037A (en) * 1993-04-09 1995-06-27 Syntex Pharmaceuticals, Ltd. Heterocyclic derivatives in the treatment of Ischaemia and related diseases

Also Published As

Publication number Publication date
WO1995004050A1 (en) 1995-02-09
ATE197047T1 (de) 2000-11-15
ES2151930T3 (es) 2001-01-16
FI960364A7 (fi) 1996-01-26
CN1042029C (zh) 1999-02-10
NO960270L (no) 1996-01-23
DE69426157D1 (de) 2000-11-23
FI960364L (fi) 1996-01-26
CN1128026A (zh) 1996-07-31
KR100299734B1 (ko) 2002-01-09
CA2168264A1 (en) 1995-02-09
US5736546A (en) 1998-04-07
DE69426157T2 (de) 2001-05-17
FI960364A0 (fi) 1996-01-26
EP0711763A1 (en) 1996-05-15
EP0711763A4 (Direct) 1996-06-12
EP0711763B1 (en) 2000-10-18

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