NO881253D0 - 1,4-disubstituerte piperazinforbindelser og fremgangsmaate for deres fremstilling. - Google Patents

1,4-disubstituerte piperazinforbindelser og fremgangsmaate for deres fremstilling.

Info

Publication number
NO881253D0
NO881253D0 NO881253A NO881253A NO881253D0 NO 881253 D0 NO881253 D0 NO 881253D0 NO 881253 A NO881253 A NO 881253A NO 881253 A NO881253 A NO 881253A NO 881253 D0 NO881253 D0 NO 881253D0
Authority
NO
Norway
Prior art keywords
group
piperazine compounds
procedures
preparation
disubstituted piperazine
Prior art date
Application number
NO881253A
Other languages
English (en)
Other versions
NO881253L (no
Inventor
Hirosada Sugihara
Katsumi Itoh
Kohei Nishikawa
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO881253D0 publication Critical patent/NO881253D0/no
Publication of NO881253L publication Critical patent/NO881253L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO881253A 1987-03-24 1988-03-22 1,4-disubstituerte piperazinforbindelser og fremgangsmaatefor deres fremstilling. NO881253L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6980487 1987-03-24

Publications (2)

Publication Number Publication Date
NO881253D0 true NO881253D0 (no) 1988-03-22
NO881253L NO881253L (no) 1988-09-26

Family

ID=13413302

Family Applications (1)

Application Number Title Priority Date Filing Date
NO881253A NO881253L (no) 1987-03-24 1988-03-22 1,4-disubstituerte piperazinforbindelser og fremgangsmaatefor deres fremstilling.

Country Status (13)

Country Link
US (1) US4880809A (no)
EP (1) EP0284359B1 (no)
CN (1) CN88101588A (no)
AT (1) ATE71373T1 (no)
AU (1) AU608580B2 (no)
DE (1) DE3867512D1 (no)
DK (1) DK155088A (no)
FI (1) FI881380A (no)
HU (1) HU202509B (no)
IL (1) IL85700A0 (no)
NO (1) NO881253L (no)
PT (1) PT87056B (no)
ZA (1) ZA882073B (no)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY102447A (en) * 1986-06-16 1992-06-30 Ciba Geigy Ag Disubtituted piperazines
EP0318235A3 (en) * 1987-11-25 1991-05-02 Takeda Chemical Industries, Ltd. Paf antagonist, 1,4-disubstituted piperazine compounds and production thereof
FI892468A (fi) * 1988-05-23 1989-11-24 Glaxo Group Ltd Piperazinderivat.
GB8823776D0 (en) * 1988-10-11 1988-11-16 Scras New 2-methoxycarbonyl sustituted n n'-di-(trimethoxybenzoyl)piperazines
GB8823775D0 (en) * 1988-10-11 1988-11-16 Scras New 2-carbonyl substituted n n'-di-(trimethoxybenzoyl)piperazines
US4997836A (en) * 1988-11-11 1991-03-05 Takeda Chemical Industries, Ltd. Trisubstituted piperazine compounds, their production and use
EP0369810A3 (en) * 1988-11-18 1991-05-02 Takeda Chemical Industries, Ltd. Paf antagonists as anti-hyperendothelinemia agents
GB8908587D0 (en) * 1989-04-15 1989-06-01 Scras Societe De Conseils De R New 2-substituted n,n'-ditrimethoxybenzoyl piperazines
US5192766A (en) * 1989-04-28 1993-03-09 Sankyo Company, Limited N-acryloylpiperazine derivatives, their preparation and their use as PAF antagonists
US5369106A (en) * 1989-04-28 1994-11-29 Sankyo Company, Limited N-acryloylpiperazine derivatives, their preparation and their use of PAF antagonists
EP0489690A1 (de) * 1990-12-05 1992-06-10 Ciba-Geigy Ag Substituierte N-Benzoyl-N'-(2-phenylethyl)-piperazine
ES2036926B1 (es) * 1991-08-08 1994-01-16 Uriach & Cia Sa J "procedimiento para la obtencion de derivados de la (2-alquil-3-piridil)metilpiperazina".
ES2062943B1 (es) * 1993-03-23 1995-11-16 Uriach & Cia Sa J Nuevos derivados de la (2-metil-3-piridil) cianometilpiperazinas.
US5716944A (en) * 1994-07-04 1998-02-10 Takeda Chemical Industries, Ltd. Phosphonic acid compounds, their production and use
ES2087038B1 (es) * 1994-11-07 1997-03-16 Uriach & Cia Sa J Nuevas piperidinas con actividad antagonista del paf.
US5859295A (en) * 1994-12-05 1999-01-12 University Of Kentucky Research Foundation Canavanine analogs and their use as chemotherapeutic agents
IL117149A0 (en) * 1995-02-23 1996-06-18 Schering Corp Muscarinic antagonists
US5889006A (en) * 1995-02-23 1999-03-30 Schering Corporation Muscarinic antagonists
US6001835A (en) * 1996-04-03 1999-12-14 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
DE19754490A1 (de) * 1997-12-09 1999-06-10 Boehringer Ingelheim Pharma Durch einen Aminocarbonylrest substituierte Bicyclen, ihre Herstellung und ihre Verwendung als Arzneimittel
CN1181065C (zh) * 2002-05-08 2004-12-22 上海医药工业研究院 芳烷甲酰烷基哌嗪衍生物及其作为脑神经保护剂的应用
CN1675154A (zh) * 2002-06-07 2005-09-28 科蒂科股份有限公司 抑制巨噬细胞移动抑制因子(mif)的细胞因子或生物活性的萘衍生物
CN1867336B (zh) 2002-06-12 2010-05-12 凯莫森特里克斯股份有限公司 1-芳基-4-取代的哌嗪衍生物及其制药用途
US7589199B2 (en) * 2002-06-12 2009-09-15 Chemocentryx, Inc. Substituted piperazines
US7842693B2 (en) * 2002-06-12 2010-11-30 Chemocentryx, Inc. Substituted piperazines
US20050256130A1 (en) * 2002-06-12 2005-11-17 Chemocentryx, Inc. Substituted piperazines
EP1720545B1 (en) * 2004-03-03 2014-10-29 ChemoCentryx, Inc. Bicyclic and bridged nitrogen heterocycles
US7435831B2 (en) * 2004-03-03 2008-10-14 Chemocentryx, Inc. Bicyclic and bridged nitrogen heterocycles

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4130646A (en) * 1975-07-25 1978-12-19 E. R. Squibb & Sons, Inc. 1,2,3,4-Tetrahydro-2-((4-(phenyl)-1-piperazinyl)methyl)-1-naphthalenols and derivatives and analogs thereof
JPS52133993A (en) * 1976-04-29 1977-11-09 Takeda Chem Ind Ltd 1.2-dihydronaphthalene derivatives and method of preparing the same
GB1574019A (en) * 1977-01-14 1980-09-03 Joullie International Sa Therapeutically useful 3,4,5-trimethoxybenzene derivatives
DK309678A (da) * 1977-07-18 1979-01-19 Sandoz Ag Fremgangsmaade til fremstilling af tetralinderivater
US4173998A (en) * 1978-02-16 1979-11-13 Carrier Corporation Formed coil assembly
CH643549A5 (de) * 1979-08-25 1984-06-15 Merz & Co N-(trimethoxybenzyl)-n'-phenylpiperazine.
IT1176613B (it) * 1984-08-14 1987-08-18 Ravizza Spa Derivati piperazinici farmacologicamente attivi e processo per la loro preparazione
AU584668B2 (en) * 1985-02-04 1989-06-01 G.D. Searle & Co. Novel heterocyclic amides useful as anti-inflammatory and anti-allergy agents
MY102447A (en) * 1986-06-16 1992-06-30 Ciba Geigy Ag Disubtituted piperazines
KR910006138B1 (ko) * 1986-09-30 1991-08-16 에자이 가부시끼가이샤 환상아민 유도체

Also Published As

Publication number Publication date
PT87056A (pt) 1988-04-01
DK155088D0 (da) 1988-03-22
HUT46899A (en) 1988-12-28
FI881380A0 (fi) 1988-03-23
IL85700A0 (en) 1988-08-31
HU202509B (en) 1991-03-28
PT87056B (pt) 1992-07-31
NO881253L (no) 1988-09-26
ATE71373T1 (de) 1992-01-15
EP0284359A1 (en) 1988-09-28
EP0284359B1 (en) 1992-01-08
AU1353988A (en) 1988-09-22
AU608580B2 (en) 1991-04-11
CN88101588A (zh) 1988-11-23
ZA882073B (en) 1989-11-29
DK155088A (da) 1988-09-25
US4880809A (en) 1989-11-14
DE3867512D1 (de) 1992-02-20
FI881380A (fi) 1988-09-25

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